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Dr J Prabhakar Patro
Professor of medicine,
The Oxford Medical College Hospital, Bengaluru
drpatrojp@gmail.com
 Dietary fibre
 BMI
 Parenteral Nutrition
 Macro-nutrition metabolism
 Severe malnutrition
 Diseases of over-nourished societies and the
need for dietary change
 Obesity
 Artificial nutrition support
 = Energy yielding nutrients
 Hemicellulose of wheat
 Increase water holding capacity of colonic
content  bulk of stool
 So relieve simple constipation
 Prevent diverticulosis
 Reduces Risk of cancer
 Pectin
 Guar gum
 Slow gastric emptying
 Contribute to satiety
 Reduce bile salt absorption plasma
cholesterol concentration
 Highest energy density of macronutrients
 37 kJ/g
 Excess  obesity
 PUFA in seeds is linoleic acid omega 6
 Alpha linolenic acid omega 3
 Are essential fatty acids.
 Precursors of prostaglandins
 Fish oils are rich in omega 3 FA
 Obesity
 A Pandemic
 Disastrous consequences
BMI > 30 kg/ m2
 25% of women in Urban India are
Obese
 Discrepancy between energy consumption
and energy expenditure
 Weight reduction
 Decreased CV risk factors
 Decreased incidence of Diabetes
 Orlistat:
 Inhibits pancreatic and gastric lipases
 Reduces hydrolysis of ingested triglycerides
 Reducing dietary fat absorption by 30%
 Not absorbed.
 Side effects are of fat malabsorption
 BMI < 18.5 kg/m2
 Under-nutrition is poorly recognised in
hospital and has serious consequences.
 Poor appetite
 Poor dental health,
 concurrent illness
 Kept ‘nil by mouth’ for investigations
 Normal diet
 Dietary supplements: protein supplements
 Enteral tube feeding: when unable to
swallow.
 Parenteral nutrition: Not for less than 1
week.
 1. Peripheral venous cannula
 2.Peripherally inserted cannula
 Weight loss + muscle wasting
 in chronic illness such as
 HIV –AIDS
 End stage organ failure
 Malignancy
Macronutrition MBBS lecture

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Macronutrition MBBS lecture

  • 1. Dr J Prabhakar Patro Professor of medicine, The Oxford Medical College Hospital, Bengaluru drpatrojp@gmail.com
  • 2.  Dietary fibre  BMI  Parenteral Nutrition
  • 3.  Macro-nutrition metabolism  Severe malnutrition  Diseases of over-nourished societies and the need for dietary change  Obesity  Artificial nutrition support
  • 4.  = Energy yielding nutrients
  • 5.
  • 6.
  • 7.  Hemicellulose of wheat  Increase water holding capacity of colonic content  bulk of stool  So relieve simple constipation  Prevent diverticulosis  Reduces Risk of cancer
  • 8.  Pectin  Guar gum  Slow gastric emptying  Contribute to satiety  Reduce bile salt absorption plasma cholesterol concentration
  • 9.  Highest energy density of macronutrients  37 kJ/g  Excess  obesity
  • 10.  PUFA in seeds is linoleic acid omega 6  Alpha linolenic acid omega 3  Are essential fatty acids.  Precursors of prostaglandins  Fish oils are rich in omega 3 FA
  • 11.
  • 12.
  • 13.
  • 14.  Obesity  A Pandemic  Disastrous consequences BMI > 30 kg/ m2  25% of women in Urban India are Obese
  • 15.  Discrepancy between energy consumption and energy expenditure
  • 16.
  • 17.
  • 18.
  • 19.
  • 20.  Weight reduction  Decreased CV risk factors  Decreased incidence of Diabetes
  • 21.
  • 22.  Orlistat:  Inhibits pancreatic and gastric lipases  Reduces hydrolysis of ingested triglycerides  Reducing dietary fat absorption by 30%  Not absorbed.  Side effects are of fat malabsorption
  • 23.
  • 24.
  • 25.  BMI < 18.5 kg/m2
  • 26.
  • 27.  Under-nutrition is poorly recognised in hospital and has serious consequences.  Poor appetite  Poor dental health,  concurrent illness  Kept ‘nil by mouth’ for investigations
  • 28.  Normal diet  Dietary supplements: protein supplements  Enteral tube feeding: when unable to swallow.  Parenteral nutrition: Not for less than 1 week.  1. Peripheral venous cannula  2.Peripherally inserted cannula
  • 29.
  • 30.  Weight loss + muscle wasting  in chronic illness such as  HIV –AIDS  End stage organ failure  Malignancy