Suitable for Biologicals

1. CHEMPRO PHARMA
PRIVATE LIMITED
Superior Quality
Higher Affordability
Reliable Service

2. Introduction
2
Infrastructure - Chemistry
Infrastructure - Analytical
F acilities
Production
Utilities
Quality Control
Lab -2 Suitable for B iologicals

3. 3
SR.NO EQUIPMENT MAKE QTY
1 Rotary evaporators KNF, Buchi, Heidolph 10
2 Circulating chillers Julabo 05
3 Vacuum Oven Shell Lab 01
4 Magnetic stirrers IKA, DLab 25
5 Jacketed reactors Murthy Lab,Goel 02
6 Overhead stirrers Ika Akhil instruments 10
7 Benchtop Autoclave (250 ml and 5 Lit ) Amar Equipment 02
8 Ozone generator (model:OZSD-3000A) Ebara Jitsugyo Co., LTD 01
9 Continuous flow reactor Corning 02
10 Immersion chiller (upto -900C) Julabo 03
Infrastructure - Chemistry

4. Infrastructure - Analytical
4
SR.NO EQUIPMENT MAKE QTY
1 HPLC Analytical Shimadzu 02
2 HPLC Analytical Waters 06
3 HPLC Preparative (Reverse Phase) Shimadzu 04
4 HPLC Preparative (Normal Phase) Waters 01
5 Super critical fluid Chromatography (SFC) Waters 01
6 HPLC-MS (Aquity QDA detector) Waters 02
7 HPLC-MS (Mass directed auto purification system) Waters 01
8 Lyophillizer LSI 02
9 Rotary evaporators Buchi, Heidolph 02
10 Water Purification System Millipore 01

5. F acilities
5

6. F acilities
6

7. Production
7
Equipments MOC Numbers Capacity
Stainless Steel Reactors SS 316 10 1.5 KL to 8.0 KL
Glass lined Reactors MSGL 4 4.0 KL to 6.3 KL
Centrifuge SS 316 5 “ 48 “
Tray Dryer SS 316 5 48 Trays to 96 Trays
Multi Mill SS 316 1 50Kg/ Hr
Sifter SS 316 1 30”
Microniser SS 316 1 10 to 20 Kg/Hour
Total Capacity Installed About 65.0 KL
KEY EQUIPMENTS IN MANUFACTURING

8. Quality Control
8
Name of the Instrument Quantity Make
HPLC 3 Shimadzu
Gas Chromatograph 2 Shimadzu & Agilant
Analytical Balance 2 Milton & RAWAG - LCGC
UV Spectrophotometer 2 Shimadzu & Analytic Jena
Polarimeter 1 Rudolph
KF Apparatus 1 Metrohm
pH Meter 1 Polomon & Datla
Millipore Water system 2 Milli-Q
Cold Chamber 4 Elanpro
Stability Chambers 1 Newtronic/Ria Analytical
Tapped density 1 Electrolab
KF Autotitrator 1 Metrohm
Photo stability chamber 1 Newtronic
MAJOR INSTRUMENTS IN QUALITY CONTROL

9. Utilities
9
Services Capacity
Electricity 360 KVA
Power Backup 380 KVA
Compressed AIR 15 CFM
Cooling system Cooling Water : 800 TR/Chilling Plant : 25 TR
Steam 1000 Kg / Hr
Purified Water 500L / Hr
Air Handling Units (Class l00K) 3 Units (11500CFM)

10. Intermediate Product List
10
SR NO INTERMEDIATES FOR API’s CAS NO END USE
1 2-Methyl Benzophenone 131-58-8 Orphenadrine Citrate
2 2-Chloro-1,3-bis(dma)trimethiniumhexafluorophosphate 249561-98-6 &
291756-76-8
Etoricoxib
3 Ketosulfone 221615-75-4 Etoricoxib
4 Methyl 6-methylnicotinate 5470-70-2 Etoricoxib
5 4-Methyl thiobenzylcyanide 38746-92-8 Etoricoxib
6 2-Butyl-1,3-Diazaspiro[4,4]non-1-en-4-OneHcl ( Spiro) 151257-01-1 Irbesartan
7 CyanoIrbesartan 138401-24-8 Irbesartan
8 Ethyl-3-(Pyridin-2yl-Amino) propionate 103041-38-9 Dabigatran
9 4-Cyano phenyl Glycine 42288-26-6 Dabigatran
10 3-[(3-A-4-MAB pyridine-2-ylamino]propionicacid ethyl ester 212322-56-0 Dabigatran
11 4-Amino Benzonitrile 873-74-5 Dabigatran

11. 1
SR NO INTERMEDIATES FOR API’s CAS NO END USE
12 Ethyl 3-(2-(Chloromethyl)-1-methyl-N-(pyridin-2-yl)-
1Hbenzo[d]imidazole-5 carboxamido)propanoate
1307233-94-8
Dabigatran
13 4-Amino-N-Hydroxy Benzimidamide 277319-62-7 Dabigatran
14 Hexyl Amino-4-Amino Phenyl Methylene carbamate 1307233-93-7 Dabigatran
15 Dabigatran etexilate 211915-06-9 Dabigatran
16 Dabigatran etexilate Mesylate 872728-81-9 Dabigatran
17 2-Aminobenzonitrile 1885-29-6 Lapatinib, Metyrosine
18 2-Acetyl benzothiophene 22720-75-8 Zileuton
19 2 Amino Thiophenol 137-07-5 Diltiazem
20 2-Amino-5-Bromopyridine 1072-97-5 Pexidartinib
21 2-Amino-5-Iodo pyridine 20511-12-0 Decoglurant
22 2-amino-5-chloro pyridine 1072-98-6 Eszopiclone, Edoxaban,
Betrixaban
23 2-Amino-3-Methyl-5-bromo pyridine 3430-21-5 Ozenoxacin
24 2-Bromo-3-Methylpyridine 3430-17-9 Lumacaftor
25 2-Bromo-5-Methylpyridine 3510-66-5 Abametapir
26 2-chloro-5-nitro pyridine 548-45-2 Netupitant
27 2-Hydroxypyridine – N-oxide 13161-30-3 Pirfenidone

12. 1
SR NO INTERMEDIATES FOR API’s CAS NO END USE
28 2-Hydroxypyridine – N-oxide 13161-30-3 Nirmatrevir,,Relebactam,Ubrogepan
29 2-Hydroxypyridine 142-08-5 Aliskiren, cabergoline, Brivaraceta
30 2-Methoxy-5-Bromopyridine 13472-85-0 Perampanel
31 2-Nitro-5-Bromo Pyridine 39856-50-3 Palbociclib
32 2-Nitro-5-Chloro Pyridine 52092-47-4 Ribociclib, Ribociclib, Succinate
33 2,5 Dibromo Pyridine 624-28-2 Abiraterone Acetate, Perampanel
34 2,5-Diphenyl oxazole 92-71-7 Lab chemicals
35 2,3-Di Amino Pyridine 452-58-4 Rimegepant, Salidroside
36 2,6-Diacetyl Pyridine 1129-30-2 Pyridinol Carbamate Plastics
37 2,6-Dibromo Pyridine 626-05-1 Lasmiditan
38 2,6-Dichloro-3-Nitro Pyridine 16013-85-7 Flupirtine
39 2,3-Dibromo-5-Chloro Pyridine 137628-17-2 Ubrogepat
40 2,5-Di Bromo-3-Methyl Pyridine 3430-18-0 Ozenoxacin
41 3,5-Dichloro-4-Amino Pyridine 22889-78-7 Roflumilast,Ronomilast
42 4-Chloro picolinamide 99586-65-9 Golvatinib
43 4-Acetyl Pyridine 1122-54-9 Cosmetic Pharmaceuticals
44 4-Hydroxy Pyridine 626-64-2 Amifampridine

13. 13
SR NO INTERMEDIATES FOR API’s CAS NO END USE
45 4-Hydroxy Coumarin 1076-38-6 Zonisamide, Warfarin, Agrochemicals
46 5,6-DI CHLORO NICOTINIC ACID 41667-95-2 Avatromboag maleate
47 5-Bromo-2-Methoxy Pyridine 13472-85-0 Perampanel
48 5-Bromo-2-Nitropyridine 39856-50-3 Ribociclib succinate
49 5-Bromo Nicotinic Acid 20826-04-4 Nicergoline
50 5,6-Dihloro nicotinamide 98-92-0 Pyridostigmine Bromide
51 5-Amino-2-Methyl Pyridine 3430-14-6 Ritlecitinib
52 5-Bromo-2-Methylpyridine 3430-13-5 Latrepirdine
53 6-Chloro Nicotinic Acid 5326-23-8 Imidacloprid
54 6-Chloro Nicotinic Acid Ethyl Ester 49608-01-7 Tazarotene
55 6-Chloro Nicotinic Acid Methyl Ester 73781-91-6 Imidacloprid, Thiacloprid
56 Amino Indian Hydrochloride 70146-15-5 Rasagiline
57 Methyl-5-Bromo nicotinate 498-94-2 Pharmaceutical Intermediate
58 Methyl Coumalate 6018-41-3 Tazarotene
59 Methyl-6-Bromo-2-Naphthoate 33626-98-1 Adapalene
60 Methyl-4-Chloropicolinate 24484-93-3 Sorafenib

14. 14
SR NO INTERMEDIATES FOR API’s CAS NO END USE
61 Methyl Picolinate 2459-07-6 Bentazon
62 Pyridine-3-Sulfonic Acid 636-73-7 pyridostigmine
63 Sodium Cyano Borohydride 25895-60-7 Reducing Agent
64 (−)-O,O′-Dibenzoyl-L-tartaric acid monohydrate 62708-56-9 Resolution Agent
New Products
SR .NO INTERMEDIATES FOR API’s CAS NO END USE
1 2-Nitro-5-Bromo Pyridine 39856-50-3
Palbociclib
2 Tert-butyl 4-(6-nitropyridin-3-yl)piperazine-1-carboxylate 571189-16-
7
3 1-Boc-4-(6-aminopyridin-3-yl)piperazine 571188-59-
5
4 5-Bromo-2,4-dichloropyrimidine 36082-50-5

15. THANK YOU!
Superior Quality
Higher Affordability
Reliable Service