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the observable Features of an organism
Physical charcteristics
the genetic make-up of an organism in
terms of the alleles present
BB bb
Homozygous
Dominant
Homozygous
Recessive
Bb
Always
expressed
CAPITAL
LETTER
Only expressed
if 2 copies
lowercase letter
1. Widow’s Peak
The gene contains 2 alleles: one for
straight hairline, which is recessive
and the other for widow’s peak,
which is dominant.
2. Bent Pinkie
If you are able to bend your
5th finger (pinkie) inwards
towards the 4th finger, it
means you have the
dominant version of the gene
responsible for the distal
segment of the finger to bend.
Naturally clasp your hands
interlocking your fingers and
thumbs .........
3. Crossing of Thumbs
When you are interlocking your fingers, observe your
thumbs. If your left thumb crosses your right thumb, this
means you have inherited one or two of the dominant
allele. If your right thumb crosses your left thumb, then
you have a pair of the recessive genes.
4. Earlobe Attachment
People have their ear lobes either attached to the
sides of their heads or hanging free. Those with
unattached earlobes have the unattached earlobe
gene as the dominant gene and the attached
earlobe as the recessive gene.
5. Tongue Rolling
If you are able to raise the sides of your tongue
together, then you have inherited the dominant gene.
Those who are unable to do this have the recessive
tongue rolling gene.
Variation
Task 4: Write down 5 physical differences you have with
someone on your table. Write down what you think causes the
difference.
Variation
Living organisms differ in several ways, even when they are
offspring of the same parents. These differences are called
variation.
Variation can be determined by genes,
the environment
or both.
Variation Variation can be determined by genes, the
environment or both.
Task 5: Copy this table and complete it with examples.
Genetic Environmental Both
The Punnet Square
Male
female
T t
T
t
Some people can roll their tongue. This is a
dominant trait (T) Let’s imagine that we cross
two people who are heterozygous. We can show
the phenotypic ratio of traits in the offspring
(F1 generation) using a punnet square.
Gametes
contain half
the genes, so
at the
top/sides of
the punnet
square, we
show the
possible
gametes we
can produce
The Punnet Square
T t
T TT
t
Some people can roll their tongue. This is a
dominant trait (T) Let’s imagine that we cross
two people who are heterozygous. We can show
the phenotypic ratio of traits in the offspring
(F1 generation) using a punnet square.
The Punnet Square
T t
T TT Tt
t
Some people can roll their tongue. This is a
dominant trait (T) Let’s imagine that we cross
two people who are heterozygous. We can show
the phenotypic ratio of traits in the offspring
(F1 generation) using a punnet square.
The Punnet Square
T t
T TT Tt
t Tt
Some people can roll their tongue. This is a
dominant trait (T) Let’s imagine that we cross
two people who are heterozygous. We can show
the phenotypic ratio of traits in the offspring
(F1 generation) using a punnet square.
The Punnet Square
T t
T TT Tt
t Tt tt
Some people can roll their tongue. This is a
dominant trait (T) Let’s imagine that we cross
two people who are heterozygous. We can show
the phenotypic ratio of traits in the offspring
(F1 generation) using a punnet square.
The Punnet Square
T t
T TT Tt
t Tt tt
Genotypic ratio:
25% TT
50% Tt
25% tt
Phenotypic ratio:
75% roller
25% non-roller
Some people can roll their tongue. This is a
dominant trait (T) Let’s imagine that we cross
two people who are heterozygous. We can show
the phenotypic ratio of traits in the offspring
(F1 generation) using a punnet square.
Remember that
you might not
always get
what you
predict – NOT
because of
mutations, but
because it is
purely due to
chance which
gametes fuse!
Looking at whole chromosomes
instead of single genes
X X
X
Y
Some genetic diseases like red-green colour
blindness are due to a faulty allele on the x-
chromosome. Why might this disorder be
more common in men than in women?
Chromosome pair 23 are
known as the sex
chromosomes. Men have
and X and Y chromosome,
and women have two X
chromosomes. What is the
phenotypic ratio of offspring
for a cross between a man
& woman?
1. The ability to tongue roll is a
dominant trait. What are the
phenotypes for a cross
between someone Tt
(tongue roller) and someone
TT (also a tongue roller)
2. Brown eye colour (B) is
dominant to having blue eye
colour (b). What are the
possible genotypes of
someone with brown eyes?
3. Give the % of each
phenotype possible if a
homozygous dominant with
brown eyes mated with a
blue-eyed person?
Monohybrid inheritance
Monohybrid inheritance is the inheritance of a single gene.
Genetic diagrams and punnett squares can be used to
describe patterns and predict probabilities of outcomes of
monohybrid crosses.
Many recessive diseases are
carried by the X chromosome and
are called sex-linked
This is a cute little black guinea pig. I want to know the genotype and
phenotype. Why can you only tell me one of them confidently?
Test Cross
Cross an organism with an unknown dominant
genotype (parent 1) with an organism that is
homozygous recessive for that trait (parent 2).
Reveals if unknown individual tested
is homozygous dominant (pure bred)
or heterozygous dominant (hybrid).
If any offspring show the recessive phenotype,
then they must have inherited one recessive
allele from parent 2, but more importantly, parent
1 MUST have had a recessive allele to pass on,
therefore making it heterozygous
What's the
chance of the
offspring having
cystic fibrosis?
What's the
chance of the
offspring having
polydactyly?
Albinism
a albino trait
A normal allele
Task 10:
1. What are the genotypes of parents A (3 & 4)? Explain how you know...
1. What are the genotypes of 15,16 and 17? Explain how you know....
Try and solve as
many of these
pedigree problems
as you can

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Lesson-3---Monohybrid-Crosses.ppt

  • 1.
  • 2.
  • 3.
  • 4.
  • 5. the observable Features of an organism Physical charcteristics the genetic make-up of an organism in terms of the alleles present
  • 7. 1. Widow’s Peak The gene contains 2 alleles: one for straight hairline, which is recessive and the other for widow’s peak, which is dominant.
  • 8. 2. Bent Pinkie If you are able to bend your 5th finger (pinkie) inwards towards the 4th finger, it means you have the dominant version of the gene responsible for the distal segment of the finger to bend.
  • 9. Naturally clasp your hands interlocking your fingers and thumbs .........
  • 10. 3. Crossing of Thumbs When you are interlocking your fingers, observe your thumbs. If your left thumb crosses your right thumb, this means you have inherited one or two of the dominant allele. If your right thumb crosses your left thumb, then you have a pair of the recessive genes.
  • 11. 4. Earlobe Attachment People have their ear lobes either attached to the sides of their heads or hanging free. Those with unattached earlobes have the unattached earlobe gene as the dominant gene and the attached earlobe as the recessive gene.
  • 12. 5. Tongue Rolling If you are able to raise the sides of your tongue together, then you have inherited the dominant gene. Those who are unable to do this have the recessive tongue rolling gene.
  • 13.
  • 14. Variation Task 4: Write down 5 physical differences you have with someone on your table. Write down what you think causes the difference.
  • 15. Variation Living organisms differ in several ways, even when they are offspring of the same parents. These differences are called variation. Variation can be determined by genes, the environment or both.
  • 16. Variation Variation can be determined by genes, the environment or both. Task 5: Copy this table and complete it with examples. Genetic Environmental Both
  • 17. The Punnet Square Male female T t T t Some people can roll their tongue. This is a dominant trait (T) Let’s imagine that we cross two people who are heterozygous. We can show the phenotypic ratio of traits in the offspring (F1 generation) using a punnet square. Gametes contain half the genes, so at the top/sides of the punnet square, we show the possible gametes we can produce
  • 18. The Punnet Square T t T TT t Some people can roll their tongue. This is a dominant trait (T) Let’s imagine that we cross two people who are heterozygous. We can show the phenotypic ratio of traits in the offspring (F1 generation) using a punnet square.
  • 19. The Punnet Square T t T TT Tt t Some people can roll their tongue. This is a dominant trait (T) Let’s imagine that we cross two people who are heterozygous. We can show the phenotypic ratio of traits in the offspring (F1 generation) using a punnet square.
  • 20. The Punnet Square T t T TT Tt t Tt Some people can roll their tongue. This is a dominant trait (T) Let’s imagine that we cross two people who are heterozygous. We can show the phenotypic ratio of traits in the offspring (F1 generation) using a punnet square.
  • 21. The Punnet Square T t T TT Tt t Tt tt Some people can roll their tongue. This is a dominant trait (T) Let’s imagine that we cross two people who are heterozygous. We can show the phenotypic ratio of traits in the offspring (F1 generation) using a punnet square.
  • 22. The Punnet Square T t T TT Tt t Tt tt Genotypic ratio: 25% TT 50% Tt 25% tt Phenotypic ratio: 75% roller 25% non-roller Some people can roll their tongue. This is a dominant trait (T) Let’s imagine that we cross two people who are heterozygous. We can show the phenotypic ratio of traits in the offspring (F1 generation) using a punnet square. Remember that you might not always get what you predict – NOT because of mutations, but because it is purely due to chance which gametes fuse!
  • 23. Looking at whole chromosomes instead of single genes X X X Y Some genetic diseases like red-green colour blindness are due to a faulty allele on the x- chromosome. Why might this disorder be more common in men than in women? Chromosome pair 23 are known as the sex chromosomes. Men have and X and Y chromosome, and women have two X chromosomes. What is the phenotypic ratio of offspring for a cross between a man & woman?
  • 24. 1. The ability to tongue roll is a dominant trait. What are the phenotypes for a cross between someone Tt (tongue roller) and someone TT (also a tongue roller) 2. Brown eye colour (B) is dominant to having blue eye colour (b). What are the possible genotypes of someone with brown eyes? 3. Give the % of each phenotype possible if a homozygous dominant with brown eyes mated with a blue-eyed person?
  • 25. Monohybrid inheritance Monohybrid inheritance is the inheritance of a single gene. Genetic diagrams and punnett squares can be used to describe patterns and predict probabilities of outcomes of monohybrid crosses.
  • 26. Many recessive diseases are carried by the X chromosome and are called sex-linked
  • 27. This is a cute little black guinea pig. I want to know the genotype and phenotype. Why can you only tell me one of them confidently? Test Cross Cross an organism with an unknown dominant genotype (parent 1) with an organism that is homozygous recessive for that trait (parent 2). Reveals if unknown individual tested is homozygous dominant (pure bred) or heterozygous dominant (hybrid). If any offspring show the recessive phenotype, then they must have inherited one recessive allele from parent 2, but more importantly, parent 1 MUST have had a recessive allele to pass on, therefore making it heterozygous
  • 28.
  • 29. What's the chance of the offspring having cystic fibrosis?
  • 30.
  • 31.
  • 32. What's the chance of the offspring having polydactyly?
  • 33.
  • 34. Albinism a albino trait A normal allele Task 10: 1. What are the genotypes of parents A (3 & 4)? Explain how you know... 1. What are the genotypes of 15,16 and 17? Explain how you know....
  • 35. Try and solve as many of these pedigree problems as you can