extended diploma synthesis report of asperin organic chemistry

1. 1
ORGANIC CHEMISTRY LABORATORY REPORT
LEARNER NAME: Hazrat Billal Group AN, AM , PM
Date 19-03-18 Experiment Number e.g 030
Title the preparation of Aspirin
Criteria covered by this practical Unit 28 P6, M4, D4
Reaction (Use Accelrys Draw or Chem Draw)
Materials
Reactants RMM
(g/mol)
Mass (g) Moles COSHH
Salicylic Acid (-
2)
Hydrozybenzoic
acid
138 2.00 0.014 R22-41
S26-39
Ethanoic acid
anhydride
102 5.00 0.048 R10-34
S26-45
Phosphoric acid 98 2.00 0.020 R34
S26-45

2. 2
ORGANIC CHEMISTRY LABORATORY REPORT
Method
Salicylic acids (2g) was added in a pear shape flask together with ethanoic
anhydride (5cm3) and 5 drop of phosphoric acids were also added. Then
the mixture was heated for 10 minutes then the ice was added and the
mixture putted to water white solid was collected. The flask was placed in
cold water bath to cool down and was left therefore, the crystal was able to
form the crude crystals was poured through a Buckner funnel so it can be
filtered, the dry aspirin was putted with (20ml) of boiling ethanol to dissolve
the crystals 10ml of ethanol was added then the filtration process was done
the precipitate was filtered to remove the impurities.
Then it was putted into a beaker and a half of the volume of the filtered
distilled water was added. It was then measured and recorded and left to
be cooled down.
Results
One mole of SA gives 1 mole of ASA
2/138 moles of SA gives 2/138 moles
Therefore, theoretical yield of ASA= 0.014 moles
Mass/ RMM= Moles
Mass = 0.0014×180= 2.6
Percentage yield A/T×100
2.14/2.16×100= 82%
Percentage yield = 82 %