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Galani Thabo
200901724
Anemia in pregnancy
Why anemia in pregnancy
• Plasma volume increase by 50%
• Red cell mass increase by 25%
• Progressive hemodilation till 35th
week
• Hemoconcetration starts @ 4 days postpartum
• Hemological changes disappear from 6-8 weeks
History
• Pica
• Hemorrhage
• Drugs (NSAIDs)
• Worm ingestion
• Diet
Hemoglobin (Diagnosis in DGMH)
• <10g/dl
Types
Iron deficiency anemia
Characteristics
• Low MCV, Low MCH
• Low ferritin
• Low saturation for iron
Effects on anemia on pregnancy
 Miscarriage
 Congenital abnormalities
 Preterm labour
 Infection
 Cardiac failure and Pulmonary edema
 Poor progress due to poor oxygen
 PPH
 Puerperal sepsis
Causes of anemia in pregnancy
 Hemorrhage (stools and epistaxis)
 Diet (low in meat)
 HIV
 Drugs (AZT, NSAIDS)
 Worms
Work up
 Iron studies
 Vitamin b12
 Folate
Treatment
• Hb <10g/dl but >2g/dl, 2 tabs, <8g/dl 3 tabs
• Oral treatment=Ferrous sulphate and Folic acid
• <6g/dl=transfuse
• After 36 weeks=Transfuse when HB is <8g/dl (no time for build up)
Megaloblastic anemia
Causes
• Folic acid deficiency
• Vitamin B12 deficiency (give vitamin B12 100micro grams)
Risk factors
• Menorrhagia
• Small interval of pregnancy
• Poor absorption
Symptomatic
• Weakness
• Tachycardia
• Fatigue
• Pallor
Treatment of anemia
Iron supplements (tablets, injection or syrup)
• Ferrous sulphate (Not in the 1st
3 months)
• Folic acid
Roles of folic acid
• Development of RBC (7-10 days for development)
• Prevent thrombosis
• Prevent neural tube defects
Two forms
• Fefol (Ferrous sulfate and folic acid)
• Hematinic (Fefol plus vitamin C(enhance absorption of folic acid))

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Anemia.pptx

  • 2. Anemia in pregnancy Why anemia in pregnancy • Plasma volume increase by 50% • Red cell mass increase by 25% • Progressive hemodilation till 35th week • Hemoconcetration starts @ 4 days postpartum • Hemological changes disappear from 6-8 weeks History • Pica • Hemorrhage • Drugs (NSAIDs) • Worm ingestion • Diet Hemoglobin (Diagnosis in DGMH) • <10g/dl Types Iron deficiency anemia Characteristics • Low MCV, Low MCH • Low ferritin • Low saturation for iron
  • 3. Effects on anemia on pregnancy  Miscarriage  Congenital abnormalities  Preterm labour  Infection  Cardiac failure and Pulmonary edema  Poor progress due to poor oxygen  PPH  Puerperal sepsis
  • 4. Causes of anemia in pregnancy  Hemorrhage (stools and epistaxis)  Diet (low in meat)  HIV  Drugs (AZT, NSAIDS)  Worms
  • 5. Work up  Iron studies  Vitamin b12  Folate
  • 6. Treatment • Hb <10g/dl but >2g/dl, 2 tabs, <8g/dl 3 tabs • Oral treatment=Ferrous sulphate and Folic acid • <6g/dl=transfuse • After 36 weeks=Transfuse when HB is <8g/dl (no time for build up) Megaloblastic anemia Causes • Folic acid deficiency • Vitamin B12 deficiency (give vitamin B12 100micro grams) Risk factors • Menorrhagia • Small interval of pregnancy • Poor absorption Symptomatic • Weakness • Tachycardia • Fatigue • Pallor
  • 7. Treatment of anemia Iron supplements (tablets, injection or syrup) • Ferrous sulphate (Not in the 1st 3 months) • Folic acid Roles of folic acid • Development of RBC (7-10 days for development) • Prevent thrombosis • Prevent neural tube defects Two forms • Fefol (Ferrous sulfate and folic acid) • Hematinic (Fefol plus vitamin C(enhance absorption of folic acid))