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Continence Problems:
Assessment and
management
Shuli Levy
Consultant Geriatrician, Hammersmith hospital,
ICHNHST
Why Continence?
• Not part of normal ageing
• Morbidity burden
• Up to 55% of women
• Up to 30% men
• 30-50% adjusted increase in hospitalisation
• Up to 70% in nursing home residents
• 2-3 x increased institutionlisation rate
• Strong association with functional decline
• Higher mortality post stroke
Overview
• How continence normally functions
• Common continence failures
• Red flags
• Assessment and management
• Who to ask
Normal continence (complex!)
• Neurological function
• Bladder function
• Sphincter function
• Cognition
• Mobility
• Dexterity
• Environment
Normal continence
Brain
• Frontal cortex
external sphincter
• Pons – learned
behaviour
• Bladder motor
cortex
Spinal cord
• Sympathetic chain
(L2)
• Parasympathetic
(S2-S4)
• Somatic supply to
external sphincter
(pudendal)
As we age …
• Bladder functional capacity decreases, residual capacity increases
• Reduced detrusor contractility
• Reduced urine flow rate
• Loss of vaginal oestrogen post menopausally
• Dryness and irritation
• Less hostile environment to bacteria (? Increased pH)
• Pelvic floor muscle atrophy
• Enlargement of prostate in men
• Increased gut transit time and colonic diverticulae  constipation
• Loss of circadian ADH / reduced RAA activity – increased nocturnal urine production
• Cerebral white matter changes
• Drugs drugs drugs
Common problems with continence
• Urinary retention
• Urinary incontinence
• Asymptomatic bacteriuria and UTI
• Medications
Urinary retention
1. Constipation
• BNO or overflow, faecal impaction on PR, dehydration, drugs
2. Infection
• pain, frequency, offensive smell, systemic illness, delirium
3. BPH
• prostatism history / medications, big prostate on PR, PSA
4. Medications / medication changes
5. Cord compression
Urinary incontinence
Neurological
Functional/
iatrogenic
Urological
Urological
• Stress incontinence
• OAB / urge
• Mixed UI
• Infection
• Atrophic vaginitis
Bladder outlet obstruction
• Constipation
• BPH
Functional /iatrogenic
• Mobility / dexterity
• Delirium & dementia
• Medications
• Metabolic (DM,
Ca++)
Neurological
• Stroke
• Cerebrovascular disease
• Autonomic neuropathy
• Demyelination
• Cord compression
Don’t forget overflow
If you like acronyms
Asymptomatic bacteriuria (ASB)
• Bacteriuria without symptoms
• Up to 10% men and 20% women over 75y
• Up to 40% men and 50% women in care homes
• Associated with dementia, incontinence and immobility
• ALL catheters become colonised
• Causes localised inflammation – 90% have white cells
• Do NOT treat
• No morbidity or mortality improvement
• Increase in resistant organisms
• No proven effect on symptoms in chronic incontinence
• High re-infection rates
Medications affecting continence
Red flags: cord compression
• Vertebral collapse
• traumatic, osteoporotic
• Known or new cancer - myeloma, solid organ metastases (look at Ca++, ALP
and FBC),
• Disc prolapse - sudden or subacute back pain
Cord compression
Urinary retention / incontinence / overflow
Faecal incontinence
Saddle anaesthesia
Lower limb weakness and sensory impairment
Loss of anal sphincter on PR
Upgoing plantars
Red flags
Haematuria
• Send for cytology
• Rule out infection / calculi
• Feel the prostate
• Imaging
Acute kidney injury
• Overflow with obstruction
Recurrent symptomatic infection
• Diabetes
• Neoplasm
Assessment
• Very history based diagnosis
• Timing of symptoms – acute / subacute / chronic
• Retention / urge / stress / neurogenic / BOO
• Trauma
• Other features
• Parity
• Drug history and medication changes
• Functional history
• Cognitive assessment
Examination
• Well or unwell
• Hydration
• Mental state – delirium
• Feel for bladder
• Dip urine for glucose, blood
• PR for faecal impaction, prostate size, anal tone, perianal anaesthesia
• Spinal tenderness
• Limited neurological examination – lower limb power, tone, sensation,
reflexes
Tests
• Renal profile
• PSA
• Calcium and ALP if worried about bony infiltration
• Inflammatory markers if worried about infection
• Spinal x-rays +/- CT if worried about fracture
• MRI if ? Cord compression
• Urine cytology
• Bladder scan / renal tract US
Who and when to ask
• Urogynaecology multidisciplinary assessment
• For urge, stress or mixed UI in females
• Stress symptoms - pelvic floor exercises, bladder training, surgery
• Drugs for OAB (fesoterodine, mirabegron)
• Topical agents / pessaries for atrophic vaginitis
• Urologists
• PSA elevated beyond BPH range
• BPH not controlled by drugs (Tamsulosin, finasteride)
• Persistent haematuria
Who and when to ask
• Neurosurgeons / spinal surgeons
• Cord compromise on imaging and symptoms
• If appears malignant may require radiotherapy rather than surgery
• If acute, likely to need decompression
• Vertebral collapse sometimes treated by kypho / vertebroplasty
• Neurologists
• Neurogenic bladder may respond to botox injections e.g. MS, spinal cord
injury
• Autonomic syndromes – diabetes, Parkinson’s disease
• Geriatrician – if in doubt, ask us
Thank you
Shuli.levy@nhs.net

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Shuli Levy Continence

  • 1. Continence Problems: Assessment and management Shuli Levy Consultant Geriatrician, Hammersmith hospital, ICHNHST
  • 2.
  • 3. Why Continence? • Not part of normal ageing • Morbidity burden • Up to 55% of women • Up to 30% men • 30-50% adjusted increase in hospitalisation • Up to 70% in nursing home residents • 2-3 x increased institutionlisation rate • Strong association with functional decline • Higher mortality post stroke
  • 4. Overview • How continence normally functions • Common continence failures • Red flags • Assessment and management • Who to ask
  • 5. Normal continence (complex!) • Neurological function • Bladder function • Sphincter function • Cognition • Mobility • Dexterity • Environment
  • 6. Normal continence Brain • Frontal cortex external sphincter • Pons – learned behaviour • Bladder motor cortex Spinal cord • Sympathetic chain (L2) • Parasympathetic (S2-S4) • Somatic supply to external sphincter (pudendal)
  • 7. As we age … • Bladder functional capacity decreases, residual capacity increases • Reduced detrusor contractility • Reduced urine flow rate • Loss of vaginal oestrogen post menopausally • Dryness and irritation • Less hostile environment to bacteria (? Increased pH) • Pelvic floor muscle atrophy • Enlargement of prostate in men • Increased gut transit time and colonic diverticulae  constipation • Loss of circadian ADH / reduced RAA activity – increased nocturnal urine production • Cerebral white matter changes • Drugs drugs drugs
  • 8. Common problems with continence • Urinary retention • Urinary incontinence • Asymptomatic bacteriuria and UTI • Medications
  • 9. Urinary retention 1. Constipation • BNO or overflow, faecal impaction on PR, dehydration, drugs 2. Infection • pain, frequency, offensive smell, systemic illness, delirium 3. BPH • prostatism history / medications, big prostate on PR, PSA 4. Medications / medication changes 5. Cord compression
  • 10. Urinary incontinence Neurological Functional/ iatrogenic Urological Urological • Stress incontinence • OAB / urge • Mixed UI • Infection • Atrophic vaginitis Bladder outlet obstruction • Constipation • BPH Functional /iatrogenic • Mobility / dexterity • Delirium & dementia • Medications • Metabolic (DM, Ca++) Neurological • Stroke • Cerebrovascular disease • Autonomic neuropathy • Demyelination • Cord compression
  • 12. If you like acronyms
  • 13. Asymptomatic bacteriuria (ASB) • Bacteriuria without symptoms • Up to 10% men and 20% women over 75y • Up to 40% men and 50% women in care homes • Associated with dementia, incontinence and immobility • ALL catheters become colonised • Causes localised inflammation – 90% have white cells • Do NOT treat • No morbidity or mortality improvement • Increase in resistant organisms • No proven effect on symptoms in chronic incontinence • High re-infection rates
  • 15. Red flags: cord compression • Vertebral collapse • traumatic, osteoporotic • Known or new cancer - myeloma, solid organ metastases (look at Ca++, ALP and FBC), • Disc prolapse - sudden or subacute back pain
  • 16. Cord compression Urinary retention / incontinence / overflow Faecal incontinence Saddle anaesthesia Lower limb weakness and sensory impairment Loss of anal sphincter on PR Upgoing plantars
  • 17. Red flags Haematuria • Send for cytology • Rule out infection / calculi • Feel the prostate • Imaging Acute kidney injury • Overflow with obstruction Recurrent symptomatic infection • Diabetes • Neoplasm
  • 18. Assessment • Very history based diagnosis • Timing of symptoms – acute / subacute / chronic • Retention / urge / stress / neurogenic / BOO • Trauma • Other features • Parity • Drug history and medication changes • Functional history • Cognitive assessment
  • 19. Examination • Well or unwell • Hydration • Mental state – delirium • Feel for bladder • Dip urine for glucose, blood • PR for faecal impaction, prostate size, anal tone, perianal anaesthesia • Spinal tenderness • Limited neurological examination – lower limb power, tone, sensation, reflexes
  • 20. Tests • Renal profile • PSA • Calcium and ALP if worried about bony infiltration • Inflammatory markers if worried about infection • Spinal x-rays +/- CT if worried about fracture • MRI if ? Cord compression • Urine cytology • Bladder scan / renal tract US
  • 21. Who and when to ask • Urogynaecology multidisciplinary assessment • For urge, stress or mixed UI in females • Stress symptoms - pelvic floor exercises, bladder training, surgery • Drugs for OAB (fesoterodine, mirabegron) • Topical agents / pessaries for atrophic vaginitis • Urologists • PSA elevated beyond BPH range • BPH not controlled by drugs (Tamsulosin, finasteride) • Persistent haematuria
  • 22. Who and when to ask • Neurosurgeons / spinal surgeons • Cord compromise on imaging and symptoms • If appears malignant may require radiotherapy rather than surgery • If acute, likely to need decompression • Vertebral collapse sometimes treated by kypho / vertebroplasty • Neurologists • Neurogenic bladder may respond to botox injections e.g. MS, spinal cord injury • Autonomic syndromes – diabetes, Parkinson’s disease • Geriatrician – if in doubt, ask us