The document compares and contrasts the circulatory systems of fish, reptiles, and mammals. It notes that all three have at least one atrium and one ventricle, and valves to prevent backflow. However, fish have a single loop circulation with mixed blood, reptiles have a double loop circulation with some mixing of oxygenated and deoxygenated blood, and mammals have a complete separation of blood types with a double loop circulation. The document also provides an overview of the main types of blood cells and their functions.