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2014-2015
FELLOWS
1
CONGESTIVE HEART FAILURE
NICK AZPIROZ
MEGAN CALDWELL
SANDRA HWANG
ELLEN KOURAKOS


2
30%
90-day
readmission rate
50%
Rate of death
within 5 years of
diagnosis
$32B
Annual medical
cost of CHF in US
$13K
Average cost of
CHF readmission
#1
Cause of
hospitalizations
for those 65+
6M
People in the
US with CHF
Response: body
compensates by
retaining fluid. Fluid
builds up in limbs and
lungs
Symptoms: edema or
swelling, shortness of
breath, difficulty
breathing, fatigue,
weakness, dizziness
Systolic heart failure:
left ventricle is
unable to contract
normally - heart is too
weak to pump blood
Diastolic heart failure:
left ventricle is
unable to relax
normally - heart is too
stiff to fill with blood
DISEASE OVERVIEW
Congestive heart failure (CHF): a chronic
condition in which the heart does not pump
blood to meet the body’s needs for oxygen
1
http://www.heart.org/idc/groups/heart-public/@wcm/@hcm/documents/downloadable/ucm_300315.pdf
2
http://circ.ahajournals.org/content/123/8/933.long


3
Stakeholder
interviews
patients, family
caregivers, nurses,
cardiologists, heart
failure specialists,
policymakers, hospital
administrators,
dietitians, pharmacists,
clinical psychologists
Shadowing
clinical rounds in heart
failure unit with heart
failure specialists
entered patient homes
during 30-day follow
up period with visiting
nurses
NEEDFINDING
Simulation
mimicked a CHF
patient’s disease
management regimen
for 2 weeks: monitor
daily weight, track
symptoms, adopt a
low-sodium diet, limit
liquid intake, increase
physical activity, and
take 10-12 (placebo)
medications
|—————————— 4 months ——————————|


4
INSIGHTS
3
http://kff.org/medicare/issue-brief/aiming-for-fewer-hospital-u-turns-the-medicare-hospital-readmission-reduction-program/
Patients are often overwhelmed by a complex disease
management regimen and prescribed lifestyle changes.
Their condition may worsen, leading to hospitalization.
22.7% of CHF patients in the US are readmitted to the
hospital within 30 days of discharge.3
patients often struggle to build new
habits, and their condition may worsen
rapid weight gain is the most
reliable objective indicator of an
upcoming readmission
When notified early, a provider can increase dosage of
diuretic by phone, keeping symptoms at bay. Patients are
told to call at 2-3 lbs weight gain in 24 hours or 5 lbs
across one week.
Even if patients have mastered tracking weight, they
often struggle to interpret and act upon this data.
health data is often not actionable
5
DESIGN PRINCIPLES
1. No new habits - for patients or providers
2. Homes are not hospitals
3. Patients are people, with lives beyond diagnosis


6
SOLUTION
Meerkat
a hardware-software solution
designed to ease the burden of chronic disease
management for patients and providers alike
Hardware: a thin scale that slips under a bathmat, fitting
seamlessly into a patient’s daily routine; takes daily weight
Software: an algorithm based on best practices from heart
failure specialists; alerts patients only when they need to
contact their provider due to rapid weight gain


7
HARDWARE


8
SOFTWARE


9
BUSINESS MODEL
Model: B2B
Customer: hospital systems
Point of distribution: during or after point of discharge
Rationale:
CHF disproportionately occurs in those who are underserved. Our selection
of a B2B model insists upon providing our solution to patients across
socioeconomic conditions.
In 2010, the Patient Protection and Affordable Care Act (ACA) established
the Hospital Readmissions Reduction Program, in which hospitals with the
highest 30-day readmission rate relative to the country’s average are
financially penalized. At this time, many hospitals use a suite of remote
monitoring tools to reduce readmissions in the 30-day follow-up period;
the equipment is returned after these 30 days.
As the ACA’s penalty will soon be extended to 90-day readmission rates,
hospitals will be pressured to seek more cost-effective, longer-term
methods of preventing readmissions post-discharge.
10
TEAM
Workspace: the Loft, Wilmington, DE
Clinical Partner: Christiana Care Health System
Sponsors & Partners: Start It Up Delaware, Delaware Community Foundation,
Discover Bank, Verizon
Nick Azpiroz | Post-fellowship, Nick returned to Stanford University to earn his
Master’s degree in Mechanical Engineering. He holds a B.S. from Stanford in
Science, Technology, and Society with a focus in Mechanical Engineering.
Megan Caldwell | Megan became Executive Director of Health for America and
COO of Meerkat Health. Prior to, she was as a management consultant at Booz
Allen Hamilton. She holds a B.S.P.A. in Policy Analysis from Indiana University.
Sandra Hwang | Sandra took the role of Research Associate at Johns Hopkins
Medical Institutions. Prior to, she worked for the World Health Organization,
Médecins Sans Frontières, and Group Health. She holds a MSPH from Johns
Hopkins Bloomberg School of Public Health and a B.S. in Biology and Society
from Cornell University.
Ellen Kourakos | Ellen stepped into the role of CEO of Meerkat Health and
COO of Health for America. Prior to, she developed surgical tools as a
Research and Development engineer at CareFusion. She holds a B.S. in
Manufacturing and Design Engineering from Northwestern University.

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HFA Portfolio Med Res (1)

  • 1. 2014-2015 FELLOWS 1 CONGESTIVE HEART FAILURE NICK AZPIROZ MEGAN CALDWELL SANDRA HWANG ELLEN KOURAKOS
  • 2. 
 2 30% 90-day readmission rate 50% Rate of death within 5 years of diagnosis $32B Annual medical cost of CHF in US $13K Average cost of CHF readmission #1 Cause of hospitalizations for those 65+ 6M People in the US with CHF Response: body compensates by retaining fluid. Fluid builds up in limbs and lungs Symptoms: edema or swelling, shortness of breath, difficulty breathing, fatigue, weakness, dizziness Systolic heart failure: left ventricle is unable to contract normally - heart is too weak to pump blood Diastolic heart failure: left ventricle is unable to relax normally - heart is too stiff to fill with blood DISEASE OVERVIEW Congestive heart failure (CHF): a chronic condition in which the heart does not pump blood to meet the body’s needs for oxygen 1 http://www.heart.org/idc/groups/heart-public/@wcm/@hcm/documents/downloadable/ucm_300315.pdf 2 http://circ.ahajournals.org/content/123/8/933.long
  • 3. 
 3 Stakeholder interviews patients, family caregivers, nurses, cardiologists, heart failure specialists, policymakers, hospital administrators, dietitians, pharmacists, clinical psychologists Shadowing clinical rounds in heart failure unit with heart failure specialists entered patient homes during 30-day follow up period with visiting nurses NEEDFINDING Simulation mimicked a CHF patient’s disease management regimen for 2 weeks: monitor daily weight, track symptoms, adopt a low-sodium diet, limit liquid intake, increase physical activity, and take 10-12 (placebo) medications |—————————— 4 months ——————————|
  • 4. 
 4 INSIGHTS 3 http://kff.org/medicare/issue-brief/aiming-for-fewer-hospital-u-turns-the-medicare-hospital-readmission-reduction-program/ Patients are often overwhelmed by a complex disease management regimen and prescribed lifestyle changes. Their condition may worsen, leading to hospitalization. 22.7% of CHF patients in the US are readmitted to the hospital within 30 days of discharge.3 patients often struggle to build new habits, and their condition may worsen rapid weight gain is the most reliable objective indicator of an upcoming readmission When notified early, a provider can increase dosage of diuretic by phone, keeping symptoms at bay. Patients are told to call at 2-3 lbs weight gain in 24 hours or 5 lbs across one week. Even if patients have mastered tracking weight, they often struggle to interpret and act upon this data. health data is often not actionable
  • 5. 5 DESIGN PRINCIPLES 1. No new habits - for patients or providers 2. Homes are not hospitals 3. Patients are people, with lives beyond diagnosis
  • 6. 
 6 SOLUTION Meerkat a hardware-software solution designed to ease the burden of chronic disease management for patients and providers alike Hardware: a thin scale that slips under a bathmat, fitting seamlessly into a patient’s daily routine; takes daily weight Software: an algorithm based on best practices from heart failure specialists; alerts patients only when they need to contact their provider due to rapid weight gain
  • 9. 
 9 BUSINESS MODEL Model: B2B Customer: hospital systems Point of distribution: during or after point of discharge Rationale: CHF disproportionately occurs in those who are underserved. Our selection of a B2B model insists upon providing our solution to patients across socioeconomic conditions. In 2010, the Patient Protection and Affordable Care Act (ACA) established the Hospital Readmissions Reduction Program, in which hospitals with the highest 30-day readmission rate relative to the country’s average are financially penalized. At this time, many hospitals use a suite of remote monitoring tools to reduce readmissions in the 30-day follow-up period; the equipment is returned after these 30 days. As the ACA’s penalty will soon be extended to 90-day readmission rates, hospitals will be pressured to seek more cost-effective, longer-term methods of preventing readmissions post-discharge.
  • 10. 10 TEAM Workspace: the Loft, Wilmington, DE Clinical Partner: Christiana Care Health System Sponsors & Partners: Start It Up Delaware, Delaware Community Foundation, Discover Bank, Verizon Nick Azpiroz | Post-fellowship, Nick returned to Stanford University to earn his Master’s degree in Mechanical Engineering. He holds a B.S. from Stanford in Science, Technology, and Society with a focus in Mechanical Engineering. Megan Caldwell | Megan became Executive Director of Health for America and COO of Meerkat Health. Prior to, she was as a management consultant at Booz Allen Hamilton. She holds a B.S.P.A. in Policy Analysis from Indiana University. Sandra Hwang | Sandra took the role of Research Associate at Johns Hopkins Medical Institutions. Prior to, she worked for the World Health Organization, Médecins Sans Frontières, and Group Health. She holds a MSPH from Johns Hopkins Bloomberg School of Public Health and a B.S. in Biology and Society from Cornell University. Ellen Kourakos | Ellen stepped into the role of CEO of Meerkat Health and COO of Health for America. Prior to, she developed surgical tools as a Research and Development engineer at CareFusion. She holds a B.S. in Manufacturing and Design Engineering from Northwestern University.