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B A N K O F A M E R I C A M E R R I L L LY N C H
GLOBAL AGRICULTURE
& CHEMICALS CONFERENCE
JIM COLLINS, Executive Vice President - Agriculture
M a r c h 1 , 2 0 1 7
2
REGULATION G The attached charts
include company information that does not
conform to generally accepted accounting
principles (GAAP). Management believes
that an analysis of this data is meaningful to
investors because it provides insight with
respect to ongoing operating results of the
company. These measures should not be
viewed as an alternative to GAAP measures
of performance. Furthermore, these
measures may not be consistent with similar
measures provided by other companies.
This data should be read in conjunction with
previously published company reports on
Forms 10-K, 10-Q, and 8-K. These reports,
along with reconciliations of non-GAAP
measures to GAAP are available on the
Investor Center of www.dupont.com under
Filings and Reports ā€“ Reconciliations and
Other Data.
FORWARD-LOOKING STATEMENTS This communication contains ā€œforward-looking statementsā€ within the meaning of
the federal securities laws, including Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of
1934, as amended. In this context, forward-looking statements often address expected future business and financial performance and financial
condition, and often contain words such as ā€œexpect,ā€ ā€œanticipate,ā€ ā€œintend,ā€ ā€œplan,ā€ ā€œbelieve,ā€ ā€œseek,ā€ ā€œsee,ā€ ā€œwill,ā€ ā€œwould,ā€ ā€œtarget,ā€ similar expressions,
and variations or negatives of these words. Forward-looking statements by their nature address matters that are, to different degrees, uncertain,
such as statements about the consummation of the proposed transaction and the anticipated benefits thereof. Forward-looking statements are not
guarantees of future performance and are based on certain assumptions and expectations of future events which may not be realized. Forward-
looking statements also involve risks and uncertainties, many of which are beyond the companyā€™s control. Some of the important factors that could
cause the companyā€™s actual results to differ materially from those projected in any such forward-looking statements are: fluctuations in energy and
raw material prices; failure to develop and market new products and optimally manage product life cycles; ability to respond to market acceptance,
rules, regulations and policies affecting products based on biotechnology and, in general, for products for the agriculture industry; outcome of
significant litigation and environmental matters, including realization of associated indemnification assets, if any; failure to appropriately manage
process safety and product stewardship issues; changes in laws and regulations or political conditions; global economic and capital markets
conditions, such as inflation, interest and currency exchange rates; business or supply disruptions; security threats, such as acts of sabotage,
terrorism or war, natural disasters and weather events and patterns which could affect demand as well as availability of products for the agriculture
industry; ability to protect and enforce the companyā€™s intellectual property rights; successful integration of acquired businesses and separation of
underperforming or non-strategic assets or businesses; and risks related to the agreement entered on December 11, 2015, with The Dow Chemical
Company pursuant to which the companies have agreed to effect an all-stock merger of equals, including the completion of the proposed
transaction on anticipated terms and timing, the ability to fully and timely realize the expected benefits of the proposed transaction and risks related
to the intended business separations contemplated to occur after the completion of the proposed transaction. Important risk factors relating to the
proposed transaction and intended business separations include, but are not limited to, (i) the completion of the proposed transaction on anticipated
terms and timing, including obtaining regulatory approvals, anticipated tax treatment, unforeseen liabilities, future capital expenditures, revenues,
expenses, earnings, synergies, economic performance, indebtedness, financial condition, losses, future prospects, business and management
strategies for the management, expansion and growth of the new combined companyā€™s operations and other conditions to the completion of the
merger, (ii) the ability of Dow and DuPont to integrate the business successfully and to achieve anticipated synergies, risks and costs and pursuit
and/or implementation of the potential separations, including anticipated timing, any changes to the configuration of businesses included in the
potential separation if implemented, (iii) the intended separation of the agriculture, material science and specialty products businesses of the
combined company post-mergers in one or more tax efficient transactions on anticipated terms and timing, including a number of conditions which
could delay, prevent or otherwise adversely affect the proposed transactions, including possible issues or delays in obtaining required regulatory
approvals or clearances, disruptions in the financial markets or other potential barriers, (iv) potential litigation relating to the proposed transaction
that could be instituted against Dow, DuPont or their respective directors, (v) the risk that disruptions from the proposed transaction will harm Dowā€™s
or DuPontā€™s business, including current plans and operations, (vi) the ability of Dow or DuPont to retain and hire key personnel, (vii) potential
adverse reactions or changes to business relationships resulting from the announcement or completion of the merger, (viii) uncertainty as to the
long-term value of DowDuPont common stock, (ix) continued availability of capital and financing and rating agency actions, (x) legislative, regulatory
and economic developments, (xi) potential business uncertainty, including changes to existing business relationships, during the pendency of the
merger that could affect Dowā€™s and/or DuPontā€™s financial performance, (xii) certain restrictions during the pendency of the merger that may impact
Dowā€™s or DuPontā€™s ability to pursue certain business opportunities or strategic transactions and (xiii) unpredictability and severity of catastrophic
events, including, but not limited to, acts of terrorism or outbreak of war or hostilities, as well as managementā€™s response to any of the
aforementioned factors. These risks, as well as other risks associated with the proposed merger, are more fully discussed in the joint proxy
statement/prospectus included in the registration statement on Form S-4 declared effective by the SEC on June 9, 2016 (File No. 333-209869), as
last amended, (the ā€œRegistration Statementā€) in connection with the proposed merger. While the list of factors presented here is, and the list of
factors presented in the Registration Statement are, considered representative, no such list should be considered to be a complete statement of all
potential risks and uncertainties. Unlisted factors may present significant additional obstacles to the realization of forward-looking statements.
Consequences of material differences in results as compared with those anticipated in the forward-looking statements could include, among other
things, business disruption, operational problems, financial loss, legal liability to third parties and similar risks, any of which could have a material
adverse effect on Dowā€™s or DuPontā€™s consolidated financial condition, results of operations, credit rating or liquidity. Neither Dow nor DuPont
assumes any obligation to publicly provide revisions or updates to any forward-looking statements regarding the proposed transaction and intended
business separations, whether as a result of new information, future developments or otherwise, should circumstances change, except as otherwise
required by securities and other applicable laws. The company undertakes no duty to publicly revise or update any forward-looking statements as a
result of future developments, or new information or otherwise, should circumstances change, except as otherwise required by securities and other
applicable laws.
DUPONT
AGRICULTURE SEGMENT
2 0 1 6 R E S U L T S2 0 1 6 AC H I E V E M E N T S
E x c e e d e d c o s t s a v i n g s a n d
o p e r a t i n g e a r n i n g s c o m m i t m e n t s
ā€¢ Delivered 7% operating earnings growth
Delivered new product pipeline
ā€¢ Grew Brazil summer season corn volume nearly
70% driven by PioneerĀ® brand hybrids with
LeptraĀ® insect protection launch
ā€¢ Launched DuPontTM ZorvecTM fungicide
Planned for synergy delivery and ensured
readiness of the new Ag business
ā€¢ Finalized plans to deliver post-merger cost
synergies
ā€¢ Progressed plans for Day One readiness
ā€¢ $9.5B Sales (-3% or -1% ex seed
sales timing)
ā€¢ $1.8B Operating Earnings (+7%)
ā€¢ 18% Operating Earnings Margin
(+ ~170 bps)
2 0 1 7 P R I O R I T I E S
ā€¢ Achieve sales, operating earnings and
cash commitments
ā€¢ Drive rapid and successful technology
launches
ā€¢ PioneerĀ® brand soybeans with Roundup
Ready 2 XtendĀ®technology
ā€¢ LeptraĀ® insect protection & PioneerĀ® brand
QromeTM products
ā€¢ DuPontTM FeXapanTM herbicide
ā€¢ DuPontTM VessaryaTM fungicide
ā€¢ DuPontTM LumisenaTM seed treatment
ā€¢ Close merger* and execute on integration
plans in preparation for intended spin**
* Pending satisfaction of customary closing conditions, including receipt of
regulatory approval
** Subject to approval of DowDuPont board
3
CONSUMER DESIRES REQUIRE
INNOVATION IN THE AG INDUSTRY
4
HEALTH &
SAFETY
KNOWING THE
ā€œFOODā€™S STORYā€
LESS FOOD WASTE
ā€œFREE FROMā€
FOOD SOURCES
ENVIRONMENTAL
STEWARDSHIP
Food demand grows at a dramatic pace. There is immense pressure to do
more with less, and be sustainable.
THE NEED FOR CROP PRODUCTIVITY
TO MEET CONSUMER DEMAND
5
Must greatly increase production
Grain yield must increase to meet demand
Farming pressures - climate, pests, pricing
Must increase output off arable land
Must sustainably manage all resources
Increased fuel and emissions standards
GLOBAL ARABLE LAND
A cres per person*
2014
0.5
2033
0.4
2014
8.5
2033
7.2
WORLD POPULATION
In B illions, Estimated
Data Source: Census Bureau for population figures and FAO for arable land figure.
*Uses 2014 arable land figures for 2033 acres per person calculation
6Source: DuPont Ag Quantitative farmer survey, 2016 (n=1,852, Global responses to date)
Growers require sustainable crop
productivity and efficiency gains as
they navigate multiple challenges.
~ 3/4 of growers ranked
ā€œproductivity per acreā€
as their #1 concern
INCREASING SEED PERFORMANCE &
PRODUCTIVITY
OPTIMIZING PROFITABILITY IN ALL
MARKET CONDITIONS
ENHANCING OUTPUT & FUNCTIONALITY
INSECT, WEED, DISEASE & NEMATODE CONTROL
AGRONOMIC PERFORMANCE VERSUS
OPERATIONAL CONSTRAINTS
PRODUCTIVITY CHALLENGES
FOR GROWERS
7
Only DuPont can collaborate with
growers acre by acre to answer these
demands. Everything we do is about
solving one problem ā€“ a complex problem
that has grown and changed with the
needs of our growing world ā€“
C R O P P R O D U C T I V I T Y
ā€œWe put a great emphasis in managing our
grain on a much more micro level ā€“ so
looking not on a field by field basis but more
on an acre by acre and even in some cases
on a sub-acre level.ā€
- DuPont Customer
BIOTECH
BREEDING
CRISPR
SEED APPLIED
TECHNOLOGY
CROP PROTECTION
DIGITAL SOLUTIONS
AGRONOMIC SOLUTIONS
DUPONTā€™S
KEY FOCUS AREAS
MULTI-PLATFORM APPROACH
TO INCREASING CROP PRODUCTIVITY
8
Corn Soy Canola, Sunflower, & Other Oilseeds Rice Fruits/Veg Other
BREEDING CRISPR BIOTECH
CROP
PROTECTION
SEED APPLIED
TECHNOLOGY
Insect
Control*
Weed
Control
Disease
Control**
Output
Traits
Yield &
Agronomics
DIGITAL
AGRONOMIC SOLUTIONS
INDUSTRY
LEADING
INNOVATION
* Includes nematodes
** Includes bacterial and fungal diseases
D I G I T A L
GROWER CHALLENGE 1: ADDRESSING
FALL ARMYWORM IN LATIN AMERICA
9
KEYSTOPERFORMANCE
P O W E R F U L P Y R A M I D
P R O T E C T I O N +
A B O V E G R O U N D
I N S E C T C O N T R O L
H I G H P E R F O R M A N C E
A C R O S S A L L I N S E C T
P R E S S U R E S
T R A I T D U R A B I L I T Y
E X C E L L E N T
E N V I R O N M E N T A L
P R O F I L E
F L E X I B I L I T Y W I T H
L A T E P L A N T I N G
U T I L I Z I N G
LeptraĀ® insect protection1. PioneerĀ® brand hybrids with
LeptraĀ® insect protection help
protect against a broad spectrum
of insects
o Brazilā€™s first 3 discrete traits
offering for above ground
insect control
o Protected by DuPontTM
DermacorĀ® seed treatment
o ~70% volume growth in Brazil
summer season
o $1B peak sales target
2. Launched with IPM* program for
trait durability and sustainable
production
3. Multiple Crop Protection solutions
to address issue
* Integrated Pest Management
Control Hybrid
G R O W E R V A L U E K E Y P R O D U C T A P P R O A C H E S
BREEDING
DIGITAL
SOLUTIONSBIOTECH
SEED APPLIED
TECHNOLOGY
CROP
PROTECTION
AGRONOMIC
SOLUTIONS
GROWER CHALLENGE 2: DEVELOPING SOLUTIONS
FOR ASIAN SOYBEAN RUST (ASR)
Vessaryaā„¢ Program
Industry standard
10
G R O W E R V A L U E
KEYSTOPERFORMANCE
T A R G E T I N G B R O A D E S T
S O L U T I O N S E T F O R
A S R I N B R A Z I L
P I P E L I N E F U L L O F N E W
N A T I V E A N D B I O T E C H
L E A D S
A P P L Y I N G C R I S P R -
C A S T E C H N O L O G Y T O
N A T I V E T R A I T S
D E M O N S T A T E D Y I E L D
B E N E F I T S A N D
D U R A B I L I T Y
E N A B L E S I N T E G R A T E D
R E S I S T A N C E
M A N A G E M E N T
1. VessaryaTM fungicide leads portfolio of
crop protection solutions with
demonstrated yield benefits
o Offers comprehensive solution to
control multiple fungal diseases
o >$200 million peak sales target
2. DuPontTM AproachĀ® Prima part of
recommended ASR regimen
3. Integrated seed research programs
deploying native and biotech
approaches with flexible deployment
o Biotech program for durable,
season-long protection
o Open innovation within biotech to
explore novel MOAs*
* Mode of Action
U T I L I Z I N G
BREEDING
DIGITAL
SOLUTIONSBIOTECH
SEED APPLIED
TECHNOLOGY
CROP
PROTECTION
AGRONOMIC
SOLUTIONS
K E Y P R O D U C T A P P R O A C H E S
CRISPR
GROWER CHALLENGE 3: ADDRESSING GLYPHOSTATE-
RESISTANT WEEDS IN NORTH AMERICA (NA)
EnviveĀ® + Glyphosate +
FeXapanā„¢
Glyphosate alone
3/15/2017 11
KEYSTOPERFORMANCE
M A X I M I Z E D
Y I E L D S
R E S I S T A N C E
M A N A G E M E N T
T E C H N O L O G Y
P R E S E R V A T I O N
L O C A L L Y
P R O V E N W E E D
C O N T R O L
S O L U T I O N S
G R O W E R V A L U E
1. PioneerĀ® brand soybeans with
Roundup Ready 2 XtendĀ® technology
o Powered by DuPont Pioneer
AYT 4.0
o Expected to comprise ~45% of
NA soybean portfolio by 2018
o >$1B peak sales target
2. FeXapanā„¢ herbicide plus VaporGripā„¢
technology
o For use on both soybeans and
cotton
3. Vigorous training initiative
o Centered on technology
stewardship and grower
experience
11
BREEDING
DIGITAL
SOLUTIONSBIOTECH
SEED APPLIED
TECHNOLOGY
CROP
PROTECTION
AGRONOMIC
SOLUTIONS
U T I L I Z I N G
K E Y P R O D U C T A P P R O A C H E S
Aggregate estimated peak sales of pipeline programs ~$20B**
PIPELINE POISED TO CONTINUE TO DELIVER
SOLUTIONS IN THE NEAR & LONG-TERM
12
*Pending regulatory approvals
** Represents the aggregate estimated peak sales of programs represented on slide; not inclusive of all pipeline programs.
RECENT LAUNCHES 2017 2018-19 BEYOND
ā€¢ PioneerĀ® brand
soybeans with
Roundup Ready
2 XtendĀ®
technology
ā€¢ PioneerĀ® brand
hybrids with
LeptraĀ® insect
protection in
Brazil
ā€¢ LeptraĀ® insect
protection in
Argentina
ā€¢ Stewarded,
limited
commercial
launch of
PioneerĀ® brand
QromeTM
products
ā€¢ PioneerĀ® brand
OptimumĀ® GLY
canola*
ā€¢ Herbicide Tolerant
Canola with
LibertyLinkĀ® trait
ā€¢ Expanded
commerciallaunch
of QromeTM
products
ā€¢ Corn & soy
insect control
ā€¢ Next-gen
soybeans
ā€¢ OptimumĀ® GLY
canola +
LibertyLinkĀ®
traits
ā€¢ Expanded
ZorvecTM launch
in AP and LA
ā€¢ VessaryaTM
disease controlin
LA
ā€¢ LumisenaTM seed
treatment
ā€¢ PyraxaltTM insect
control*
ā€¢ ZorvecTM
expansion into
EMEA*
ā€¢ New class of
nematicides
ā€¢ New MOA -
disease control
SEEDS &
T RAIT S
CROP
PROTECTION
ā€¢ CyazypyrĀ®
insect control
ā€¢ ZorvecTM
disease control
ā€¢ DuPontTM
LumidermTM,
LumiviaTM and
DermacorĀ® seed
treatment
Higher yield with no disruption to the native trait characteristics
LEADERSHIP
IN BREEDING
E L I T E G E R M P L A S M
ā€¢ Next-generation breeding technologies delivering 2X increase over historical rate of gain*
ā€¢ Improved global integration across wide range of DuPont Pioneer germplasm & crops
ā€¢ Driving productivity in marker lab enabling a 10x increase in throughput and a 10x
decrease in cost per marker data point**
ā€¢ From 2010 to 2016, breeding pipeline increased by 150% in scale and quality
FIRST COMMERCIAL
HYBRID
MANAGED DROUGHT
TRIALS
MARKER ASSISTED SELECTION
AND ANALYTICS
BIOTECH
TRAIT
INTEGRATION
GENOMIC
PREDICTION
CRISPR-CAS
E X T E N S I V E G E R M P L A S M L I B R A RY
1926 1957
1995
1998
2009
2016
P R O D U C T I V I T Y
1905
2025
Continued excellence in breeding, increasing genetic diversity, efficiency and quality of product development.
BUILDING UPON OVER 90 YEARS
OF PLANT BREEDING LEADERSHIP
* 100-113 CRM germplasm pipeline
**Over ten-year period
13
INFINITE
YIELD
POSSIBILITIES
BROAD AGRICULTURAL APPLICATIONS OF CRISPRNEAR-TERM PRODUCTS TO MARKET
NORTHERN CORN LEAF BLIGHT
ā€¢ Devastating global disease with
potential to cause $1.6B* annual
losses in North America alone
ā€¢ Leveraging germplasm base
ā€¢ Utilizing native genes, genomic
selection, and genome editing
ā€¢ Providing sustainable grower
solutions
NORTHERN CORN LEAF BLIGHT
READINESS:
First half of next decade
WAXY CORN HYBRIDS
ā€¢ Foundational for future product
development
ā€¢ First commercial agricultural
product
ā€¢ To market by end of decade
CRISPR genome editing technology for advanced breeding
LEADERSHIP IN CRISPR
ADVANCED BREEDING TECHNOLOGY
Products, benefits and concepts described herein will not be offered for sale or distribution until completion of field testing and applicable regulatory reviews.
* Source: Internal analysis and USDA.
DISEASE
RESISTANCE
YIELD & YIELD
STABILITY
DROUGHT
TOLERANCE
OUTPUT
TRAITS
MATURITY
CORN ā€¢ ā€¢ ā€¢ ā€¢
SOY ā€¢ ā€¢ ā€¢
CANOLA ā€¢ ā€¢ ā€¢
RICE ā€¢ ā€¢ ā€¢ ā€¢
WHEAT ā€¢ ā€¢
SUNFLOWER ā€¢ ā€¢
14
NORTH AMERICA
PIONEERĀ® BRAND CORN
15
D E E P P O R T F O L I O O F C O R N T O C O V E R
N O R T H A M E R I C A N P R O D U C T I O N N E E D S
ADVANTAGED YIELD PERFORMANCE*
C O R N H Y B R I D S P R E S E N T E D I N C H A RT R E P R E S E N T
~50% O F N O RT H A M E R I C A N C O R N V O L U M E
<103 C R M 103 ā€“ 113 C RM >113 C R M
0BU/AAdvantage13
H I G H L I G H T S
ā€¢ Across over 21,000 competitor
comparisons, and across all
maturity zones, leader PioneerĀ®
brand corn products produce an
advantaged yield performance
ā€¢ In 2016, ~50% of the North
American corn volume was from
hybrids released in the last 2 years
ā€¢ 2017 portfolio includes 29 new
genetic platforms and 53 new
products
ā€¢ Full breeding pipeline of future
products
World Record
of 532 bu/acre
Source: 2016 Pioneer on-farm trial database. Customer comparisons based on 2016 yield results including data from weight wagon and PKP trials for all PioneerĀ® brand hybrids against all competitors. Individual results may
vary. All data weighted by comparisons within 4CRM and adjusted to 15% moisture. Products performance is variable and subject to any number of environmental, disease and pest pressures.
High-yield performance with proven insect protection
PIONEERĀ® BRAND
QROMEā„¢ PRODUCTS
BREEDING
DIGITAL
SOLUTIONS
U T I L I Z I N G
BIOTECH
AGRONOMIC
SOLUTIONS
Q R O M E ā„¢
p r o d u c t s
ā€¢ Limited commercial launch in
2017 growing season across
Western U.S. Corn Belt*
ā€¢ Enables PioneerĀ® brand triple-
stack product mix to increase
significantly in the next five years
ā€¢ Strengthens yield performance
in corn rootworm areas
ā€¢ Improved integration across a
broad range of PioneerĀ®
germplasm
ā€¢ ~$2B peak sales target
YIELD
E N H A N C E D Y I E L D
P E R F O R M A N C E
E X P A N D E D B R E E D I N G
A P P L I C A B I L I T Y
ELITE
PRODUCTS
4 - 7 bu/A
INCREASE
QROMEā„¢
PRODUCTS
190Yield(bu/A)205
GERMPLASM
ELITE
PRODUCTS
QROMEā„¢
PRODUCTS
%OFGERMPLASM
COMPATABILITY
Source: DuPont Pioneer Research Trials
* QromeTN products are approved for cultivation in the U.S. and Canada and have also received import approval in a
number of importing countries. DuPont Pioneer continues to pursue additional import approvals for QromeTM
products, including in China, in accordance with Excellence Through Stewardship Product Launch Guidance.
16
~50%
INCREASE
PIONEERĀ® BRAND A-SERIES SOYBEAN LAUNCH
POWERED BY ACCELERATED YIELD TECHNOLOGY 4.0
*Data is based on average of 2016 comparisons made across all major soybean growing
areas of the United States through Nov. 29, 2016. Comparisons are against all competitors
in Pioneer IMPACTā„¢ plots unless otherwise stated, and within +/-03 RM of the competitive
brand. Product responses are variable and subject to any number of environmental,
disease and pest pressures. Individual results may vary. Multi-year and multi-location data
are a better predictor of future performance. 17
DRAMATIC INCREASE IN SOY VARIETY TESTING VIA
ACCELERATED YIELD TECHNOLOGY (AYT 4.0)
PIONEER
PREDICTIVE
BREEDING
APPLICABLE
FOR ALL
CROPS: Use AYT
4.0 to select only
those with the
best gene
combinations for
field evaluation.
100,000
2012 2017
2 Million
20x INCREASEā€¢ DuPont Pioneerā€™s highest yielding
line of soybean varieties ever
ā€¢ Launched 54 new A-Series varieties
for 2017, including 30 varieties
with Roundup Ready 2 XtendĀ®
technology
ā€¢ Forecasted to comprise nearly 40%
of NA soybean volume by 2018
ā€¢ Generates greater than 2bu/A yield
advantage*
ā€¢ Leading agronomic package of
defense traits to meet local needs
FIELD TESTS
PER YEAR
MOLECULAR
MARKER TESTS
PER YEAR
0BU/A
Advantage
<2 R M 2-3 R M >3 R M
A-SERIES SOYBEANS WITH
ROUNDUP READY 2 XTENDĀ® TECHNOLOGY LEADERS *
8
Unmatched knowledge of the customer, global insights and information
applied locally enables growers to achieve better performance in the field
DUPONT PIONEERā€™S
ADVANTAGED ROUTE TO MARKET
18
RI GHT PRODUC T RI GHT ACRE
P I O N E E R S A L E S
R E P R E S E N T A T I V E S
A V A I L A B L E 2 4 / 7
W O R K D I R E C T L Y W I T H
G R O W E R
F L E X I B L E P R O G R A M S
W I N N I N G S T R A T E G Y
S P A N S M U L T I P L E
R E G I O N S
C O N N E C T E D T O L O C A L
M A R K E T I S S U E S
I N - M A R K E T
D E V E L O P M E N T &
C O L L A B O R A T I O N
C R O P M A N A G E M E N T
I N S I G H T S
E X C L U S I V E L Y S E L L S
P I O N E E R Ā® B R A N D S E E D
Provides grower with average gross return of $22 per acre*
ENCIRCASM
SERVICES
19
Source: 2016 DuPont Pioneer on-farm trials.
E N C I R C A S M S E R V I C E S B Y T H E
N U M B E R S
ADVANTAGE WITH ENCIRCASM
NITROGEN SERVICE*
YIELD NITROGEN
+6 bu/A -8 lbs.
ā€œTechnology has played a huge part of our ability to
expand productionā€¦ . Weā€™ve seen over the last five
years a significant leap in all field yield levels, and I think
thatā€™s going to be the number one contributor to us
being able to continue to grow and continue to
thrive.ā€
- DuPont Grower
>75 million acres of operational data
12 million acres advised on product
placement
2+ million paid acres
$7 average gross revenue per paid acre
67% of the time our recommendation beat
the current grower practice*
6 bushel per acre yield advantage*
8 pounds less nitrogen per acre*
$22 per acre average grower return*
*Source: Data from 420 DuPont Pioneer research trials conducted in 2015 and 2016. Amounts shown
are averages based on gross (before service fee) revenue and standardized input and grain market
prices.
The intersection of crop protection and seed businesses
DUPONTā„¢
SEED TREATMENT ENTERPRISE
20
TREATED WITH
LUMIDERMTM
TREATED WITH
DERMACORĀ®
TREATED WITH
LUMIVIATM
TREATED WITH
LUMISENATM
U T I L I Z I N G
DIGITAL
SOLUTIONS
CROP
PROTECTION
AGRONOMIC
SOLUTIONS
SEED APPLIED
TECHNOLOGY
SEED TREATMENT
ENTERPRISE
ā€¢ 4 products launched in
multiple countries
ā€¢ > $400 million peak sales
ā€¢ Extensive development
and field testing
capabilities
ā€¢ Continuous testing and
selection of pest products
to compliment genetics
ā€¢ Develop and provide
advanced seed applied
technologies to improve
grower productivity
Innovative, game-changing technology: A better crop for a better business
DUPONTā„¢
ZORVECā„¢ DISEASE CONTROL
21
*Depending on environmental conditions.
Z O R V E C ā„¢
ā€¢ >$200 million peak sales
target
ā€¢ Launched in over 10
countries
ā€¢ European (EU) regulatory
acceptance for tech
material. Preparing for
2018 large EU launches
ā€¢ Enables growers to reduce
total costs U T I L I Z I N G
Rainfast after 20 minutes
Delivers 3 to 4 more days of disease
control than the competition, even
under high disease pressure*
Offers protection of new growth
DIGITAL
SOLUTIONS
AGRONOMIC
SOLUTIONS
CROP
PROTECTION
DELIVERING CONSISTENT DISEASE CONTROL
The next game changer for insect control in Asia Pacific rice
DUPONTā„¢
PYRAXALTā„¢ INSECT CONTROL
DuPontTM PyraxaltTM is not registered for use or sale in the United States and other countries. No offer for sale, sale or use of these products are permitted prior to the issuance of the country level
registration.
22
P Y R A X A L T ā„¢
ā€¢ Novel activity for control of a
wide spectrum of hopper insects
in rice
ā€¢ New standard for high-potency
low-use rate and favorable
environmental profile
ā€¢ Registration dossiers submitted
in key rice countries; first sales
in 2018
ā€¢ >$150 million peak sales target
PLANT HOPPERS
THREATEN 87% OF
WORLD RICE
PRODUCTION
AFFECTED COUNTRIES
U T I L I Z I N G
DIGITAL
SOLUTIONS
AGRONOMIC
SOLUTIONS
CROP
PROTECTION
H O P P E R B U R N
YIELDING
RESULTS
23
M E E T I N G
G R O W E R S ā€™
N E E D S
We customize our products and services to
meet the needs of each crop/field/acre
ā€¢ enabling higher yield,
ā€¢ more consistent results,
ā€¢ and better returns.
C O N T I N U O U S
I N N O V A T I O N
By continually innovating, we are able to
help growers meet the rising demand
ā€¢ sustainably,
ā€¢ responsibly,
ā€¢ and safely.
I M P R O V E D
R E T U R N
The ability to provide integrated
solutions enables us to better meet
grower needs while delivering increased
productivity and profitability for both
the customer and DuPont.
23
ā€œOne of the most important things that
DuPont has been is an agronomy partner
which has been a huge aspect to our
growth in production.ā€
ā€“ DuPont Customer
24
Copyright Ā© 2017 DuPont or its affiliates. All rights reserved.
The DuPont Oval Logo, DuPontā„¢ and all products denoted with ā„¢ or Ā® are registered trademarks or trademarks
of E. I. du Pont de Nemours and Company or its affiliates.
25
R&D DISCOVERY AND
COMMERCIALIZATION PROCESS
Discovery
ProofofConcept
Advanced
Development
Early
Development
Pre-launch
Launch
D
1
2 3
4
L
ā€¢ Select product
target
ā€¢ Identify leads
ā€¢ Product
Stewardship
ā€¢ Crop transformation
ā€¢ Demonstrate proof
of concept
ā€¢ Gene and construct
optimization
ā€¢ Production
transformation
ā€¢ Event
characterization
ā€¢ Event development
ā€¢ Initiate regulatory
testing
ā€¢ Advanced field
testing
ā€¢ Regulatory testing
ā€¢ Regulatory dossier
submission
ā€¢ Regulatory testing
ā€¢ Trait introgression
and seed ramp up
ā€¢ Pre-marketing
ā€¢ IMPACTā„¢ trials
ā€¢ Regulatory
approvals
ā€¢ Commercial sales
begin
ā€¢ Product
stewardship
26
CORN BIOTECH PIPELINE
27
CORN
R&D PHASE MARKETS
(ā—) PRIMARY
MARKET
OPPORTUNITY
(MM ACRES)
Est.
Peak
Sales
D 1 2 3 4 L NA EU LA AP AF <50 50-100 >100 H / M / L
HIGHLIGHTED PRODUCT CONCEPTS
PioneerĀ® brand Qromeā„¢ products ā— H
BIOTECH SOLUTIONS
New MOA Lepidopteran Protection III ā— ā— ā— ā—
New MOA Coleopteran Protection III ā—
Yield & Yield Stability ā—
LIMITED
R&D Phases D = Discovery, 1 = Proof of Concept, 2 = Early Development, 3 = Advanced Development, 4 = Pre-Launch, Launch = Available for commercial sale or use
Market Opportunity Market Opportunity reflects total acres in Primary Markets in millions
Estimated Peak Sales Range provided for projects Phase 3 or later in pipeline: L = $0-100MM, M = $100-500MM, H = $500MM+
Arrow indicates advancement or addition (2/16-2/17)
Products, concepts, or benefits described herein will not be offered for sale or distribution until completion of field testing and applicable regulatory reviews. Each Phase represents only the
lead event for each program. Discovery and market evaluation is an ongoing process for all programs in the pipeline.
SOYBEAN BIOTECH PIPELINE
28
SOYBEAN
R&D PHASE MARKETS
(ā—) PRIMARY
MARKET
OPPORTUNITY
(MM ACRES)
Est.
Peak
Sales
D 1 2 3 4 L NA EU LA AP AF <50 50-100 >100 H / M / L
HIGHLIGHTED PRODUCT CONCEPTS
PioneerĀ® brand PlenishĀ®
high oleic soybeans^ ā— M
Multiple Mode Herbicide Tolerance ā— ā— H
BIOTECH SOLUTIONS
Increased Soybean Oil & Improved Meal Value ā— ā—
Lepidopteran Protection ā—
Hemipteran Protection ā—
Asian Soybean Rust Resistance ā—
R&D Phases D = Discovery, 1 = Proof of Concept, 2 = Early Development, 3 = Advanced Development, 4 = Pre-Launch, Launch = Available for commercial sale or use
Market Opportunity Market Opportunity reflects total acres in Primary Markets in millions
Estimated Peak Sales Range provided for projects Phase 3 or later in pipeline: L = $0-100MM, M = $100-500MM, H = $500MM+
Arrow indicates advancement or addition (2/16-2/17)
Products, concepts, or benefits described herein will not be offered for sale or distribution until completion of field testing and applicable regulatory reviews. Each Phase represents only the
lead event for each program. Discovery and market evaluation is an ongoing process for all programs in the pipeline.
ADDITIONAL CROPS BIOTECH PIPELINE
29
ADDITIONAL
CROPS
R & D PHASE MARKETS
(ā—) PRIMARY
MARKET
OPPORTUNITY
(MM ACRES)
Est.
Peak
Sales
D 1 2 3 4 L NA EU LA AP AF <50 50-100 >100 H / M / L
CANOLA
OptimumĀ®
GLY herbicide tolerance hybrids ā— ā— M
Herbicide Tolerant Canola with the LibertyLinkĀ®
trait ā— L
Herbicide Tolerant Canola with the OptimumĀ®
GLY & LibertyLinkĀ®
trait stack
ā— L
R&D Phases D = Discovery, 1 = Proof of Concept, 2 = Early Development, 3 = Advanced Development, 4 = Pre-Launch, Launch = Available for commercial sale or use
Market Opportunity Market Opportunity reflects total acres in Primary Markets in millions
Estimated Peak Sales Range provided for projects Phase 3 or later in pipeline: L = $0-100MM, M = $100-500MM, H = $500MM+
Arrow indicates advancement or addition (2/16-2/17)
Products, concepts, or benefits described herein will not be offered for sale or distribution until completion of field testing and applicable regulatory reviews. Each Phase represents only the
lead event for each program. Discovery and market evaluation is an ongoing process for all programs in the pipeline.
30
CROP PROTECTION
R&D Phase1 Target Market (Shaded) Estimated
Peak Sales
2
D 1 2 3 4 L F&V Rice Cereals Corn Oil Seed
WEED CONTROL
New class of grass and broad leaf weed control
New mode of action grass and broad leaf weed control
New class of grass and broad leaf weed control
New mode of action grass and broad leaf weed control
INSECT and NEMATODE CONTROL
New class of insect control for piercing/sucking pests
Fluazaindolizine, new mode of action nematicide M
Pyraxaltā„¢, new class of insect control for piercing pests M
CyazypyrĀ® cross-spectrum insect control M
Lumiviaā„¢ Seed Treatment M
Lumiposaā„¢ Seed Treatment L
DISEASE CONTROL
Broad-spectrum disease control, new mode of action
Zorvecā„¢ oomycete control, new mode of action M
Penthiopyrad broad-spectrum disease control M
Lumisenaā„¢ Seed Treatment L
CROP PROTECTION PIPELINE
New
R&D Phases D = Discovery, 1 = Proof of Concept, 2 = Early Development, 3 = Advanced Development, 4 = Pre-Launch, Launch = Available for commercial sale or use
Estimated Peak Sales Range provided for projects Phase 3 or later in pipeline: L = $0-100MM, M = $100-500MM, H = $500MM+
Arrow indicates advancement or addition (2/16-2/17)
Products, concepts, or benefits described herein will not be offered for sale or distribution until completion of field testing and applicable regulatory reviews. Each Phase represents only the lead event for each program. Discovery and market
evaluation is an ongoing process for all programs in the pipeline.
New
AgrisureĀ® and Agrisure VipteraĀ® are registered trademarks of, and used under license from, a Syngenta Group Company. AgrisureĀ® technology incorporated into these seeds is commercialized under a license from
Syngenta Crop Protection AG. HerculexĀ® Insect Protection technology by Dow AgroSciences and Pioneer Hi-Bred. HerculexĀ® and the HX logo are registered trademarks of Dow AgroSciences LLC. LibertyĀ®, LibertyLinkĀ® ,
and the Water Droplet Design are registered trademarks of Bayer. YieldGardĀ®, the YieldGard Corn Borer design, and Roundup ReadyĀ® are trademarks of Monsanto Technology LLC used under license.
DO NOT APPLY DICAMBA HERBICIDE IN-CROP TO SOYBEANS WITH Roundup Ready 2 XtendĀ® technology unless you use a dicamba herbicide product that is specifically labeled for that use in the
location where you intend to make the application. IT IS A VIOLATION OF FEDERAL AND STATE LAW TO MAKE AN IN-CROP APPLICATION OF ANY DICAMBA HERBICIDE PRODUCT ON SOYBEANS WITH
Roundup Ready 2 XtendĀ® technology, OR ANY OTHER PESTICIDE APPLICATION, UNLESS THE PRODUCT LABELING SPECIFICALLY AUTHORIZES THE USE. Contact the U.S. EPA and your state pesticide
regulatory agency with any questions about the approval status of dicamba herbicide products for in-crop use with soybeans with Roundup Ready 2 XtendĀ® technology.
ALWAYS READ AND FOLLOW PESTICIDE LABEL DIRECTIONS. Soybeans with Roundup Ready 2 XtendĀ® technology contain genes that confer tolerance to glyphosate and dicamba. Glyphosate herbicides
will kill crops that are not tolerant to glyphosate. Dicamba will kill crops that are not tolerant to dicamba.
Roundup Ready 2 XtendĀ®, and VaporGripā„¢ are trademarks of Monsanto Technology LLC used under license.
Pioneer is a member of Excellence Through StewardshipĀ® (ETS). Pioneer products are commercialized in accordance with ETS Product Launch Stewardship Guidance and in compliance with the Pioneer
policies regarding stewardship of those products. Crops and materials containing biotech traits may only be exported to or used, processed, or sold in jurisdictions where all necessary regulatory
approvals have been granted for those crops and materials. It is a violation of national and international laws to move materials containing biotech traits across borders into jurisdictions where their import
is not permitted. Growers should discuss these issues with their purchaser or grain handler to confirm the purchaser or handlerā€™s position on products being purchased. Excellence Through StewardshipĀ®
is a registered trademark of the Biotechnology Industry Organization.
^ EXPORT APPROVAL NOTICE: These products are authorized for planting in the United States and Canada. While many import market authorizations are in place, grain and byproducts produced from grain containing
this technology may not be authorized in some markets. Growers that use this product are required and agree to adhere to the stewardship requirements as outlined in the Pioneer Product Use Guide and product-specific
stewardship requirements for this product. For questions regarding product stewardship and biotech traits, please contact your sales representative or refer to www.pioneer.com/stewardship. Growers are required to
discuss trait acceptance and grain purchasing policies with their local grain handler prior to delivering grain containing biotech traits.
QromeTM products are approved for cultivation in the U.S. and Canada and have also received import approval in a number of importing countries. DuPont Pioneer continues to pursue additional import approvals for
QromeTM products, including in China, in accordance with Excellence Through Stewardship Product Launch Guidance.
EncircaSM services are provided subject to the terms and conditions of purchase which are part of the purchase documents. EncircaSM services provides estimates and management suggestions based on statistical and
agronomic models. EncircaSM services is not a substitute for sound field monitoring and management practices. Individual results may vary and are subject to a variety of factors, including weather, disease and pest
pressure, soil type and management practices.
Ā®, SM, TM Trademarks and service marks of DuPont, Pioneer or their respective owners. Ā© 2017 PHII. PioneerĀ® brand products are provided subject to the terms and conditions of purchase
which are part of the labeling and purchase documents.
^
31Updated as of March 15, 2017 to incorporate Pioneer branding.

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  • 1. 1 B A N K O F A M E R I C A M E R R I L L LY N C H GLOBAL AGRICULTURE & CHEMICALS CONFERENCE JIM COLLINS, Executive Vice President - Agriculture M a r c h 1 , 2 0 1 7
  • 2. 2 REGULATION G The attached charts include company information that does not conform to generally accepted accounting principles (GAAP). Management believes that an analysis of this data is meaningful to investors because it provides insight with respect to ongoing operating results of the company. These measures should not be viewed as an alternative to GAAP measures of performance. Furthermore, these measures may not be consistent with similar measures provided by other companies. This data should be read in conjunction with previously published company reports on Forms 10-K, 10-Q, and 8-K. These reports, along with reconciliations of non-GAAP measures to GAAP are available on the Investor Center of www.dupont.com under Filings and Reports ā€“ Reconciliations and Other Data. FORWARD-LOOKING STATEMENTS This communication contains ā€œforward-looking statementsā€ within the meaning of the federal securities laws, including Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. In this context, forward-looking statements often address expected future business and financial performance and financial condition, and often contain words such as ā€œexpect,ā€ ā€œanticipate,ā€ ā€œintend,ā€ ā€œplan,ā€ ā€œbelieve,ā€ ā€œseek,ā€ ā€œsee,ā€ ā€œwill,ā€ ā€œwould,ā€ ā€œtarget,ā€ similar expressions, and variations or negatives of these words. Forward-looking statements by their nature address matters that are, to different degrees, uncertain, such as statements about the consummation of the proposed transaction and the anticipated benefits thereof. Forward-looking statements are not guarantees of future performance and are based on certain assumptions and expectations of future events which may not be realized. Forward- looking statements also involve risks and uncertainties, many of which are beyond the companyā€™s control. Some of the important factors that could cause the companyā€™s actual results to differ materially from those projected in any such forward-looking statements are: fluctuations in energy and raw material prices; failure to develop and market new products and optimally manage product life cycles; ability to respond to market acceptance, rules, regulations and policies affecting products based on biotechnology and, in general, for products for the agriculture industry; outcome of significant litigation and environmental matters, including realization of associated indemnification assets, if any; failure to appropriately manage process safety and product stewardship issues; changes in laws and regulations or political conditions; global economic and capital markets conditions, such as inflation, interest and currency exchange rates; business or supply disruptions; security threats, such as acts of sabotage, terrorism or war, natural disasters and weather events and patterns which could affect demand as well as availability of products for the agriculture industry; ability to protect and enforce the companyā€™s intellectual property rights; successful integration of acquired businesses and separation of underperforming or non-strategic assets or businesses; and risks related to the agreement entered on December 11, 2015, with The Dow Chemical Company pursuant to which the companies have agreed to effect an all-stock merger of equals, including the completion of the proposed transaction on anticipated terms and timing, the ability to fully and timely realize the expected benefits of the proposed transaction and risks related to the intended business separations contemplated to occur after the completion of the proposed transaction. Important risk factors relating to the proposed transaction and intended business separations include, but are not limited to, (i) the completion of the proposed transaction on anticipated terms and timing, including obtaining regulatory approvals, anticipated tax treatment, unforeseen liabilities, future capital expenditures, revenues, expenses, earnings, synergies, economic performance, indebtedness, financial condition, losses, future prospects, business and management strategies for the management, expansion and growth of the new combined companyā€™s operations and other conditions to the completion of the merger, (ii) the ability of Dow and DuPont to integrate the business successfully and to achieve anticipated synergies, risks and costs and pursuit and/or implementation of the potential separations, including anticipated timing, any changes to the configuration of businesses included in the potential separation if implemented, (iii) the intended separation of the agriculture, material science and specialty products businesses of the combined company post-mergers in one or more tax efficient transactions on anticipated terms and timing, including a number of conditions which could delay, prevent or otherwise adversely affect the proposed transactions, including possible issues or delays in obtaining required regulatory approvals or clearances, disruptions in the financial markets or other potential barriers, (iv) potential litigation relating to the proposed transaction that could be instituted against Dow, DuPont or their respective directors, (v) the risk that disruptions from the proposed transaction will harm Dowā€™s or DuPontā€™s business, including current plans and operations, (vi) the ability of Dow or DuPont to retain and hire key personnel, (vii) potential adverse reactions or changes to business relationships resulting from the announcement or completion of the merger, (viii) uncertainty as to the long-term value of DowDuPont common stock, (ix) continued availability of capital and financing and rating agency actions, (x) legislative, regulatory and economic developments, (xi) potential business uncertainty, including changes to existing business relationships, during the pendency of the merger that could affect Dowā€™s and/or DuPontā€™s financial performance, (xii) certain restrictions during the pendency of the merger that may impact Dowā€™s or DuPontā€™s ability to pursue certain business opportunities or strategic transactions and (xiii) unpredictability and severity of catastrophic events, including, but not limited to, acts of terrorism or outbreak of war or hostilities, as well as managementā€™s response to any of the aforementioned factors. These risks, as well as other risks associated with the proposed merger, are more fully discussed in the joint proxy statement/prospectus included in the registration statement on Form S-4 declared effective by the SEC on June 9, 2016 (File No. 333-209869), as last amended, (the ā€œRegistration Statementā€) in connection with the proposed merger. While the list of factors presented here is, and the list of factors presented in the Registration Statement are, considered representative, no such list should be considered to be a complete statement of all potential risks and uncertainties. Unlisted factors may present significant additional obstacles to the realization of forward-looking statements. Consequences of material differences in results as compared with those anticipated in the forward-looking statements could include, among other things, business disruption, operational problems, financial loss, legal liability to third parties and similar risks, any of which could have a material adverse effect on Dowā€™s or DuPontā€™s consolidated financial condition, results of operations, credit rating or liquidity. Neither Dow nor DuPont assumes any obligation to publicly provide revisions or updates to any forward-looking statements regarding the proposed transaction and intended business separations, whether as a result of new information, future developments or otherwise, should circumstances change, except as otherwise required by securities and other applicable laws. The company undertakes no duty to publicly revise or update any forward-looking statements as a result of future developments, or new information or otherwise, should circumstances change, except as otherwise required by securities and other applicable laws.
  • 3. DUPONT AGRICULTURE SEGMENT 2 0 1 6 R E S U L T S2 0 1 6 AC H I E V E M E N T S E x c e e d e d c o s t s a v i n g s a n d o p e r a t i n g e a r n i n g s c o m m i t m e n t s ā€¢ Delivered 7% operating earnings growth Delivered new product pipeline ā€¢ Grew Brazil summer season corn volume nearly 70% driven by PioneerĀ® brand hybrids with LeptraĀ® insect protection launch ā€¢ Launched DuPontTM ZorvecTM fungicide Planned for synergy delivery and ensured readiness of the new Ag business ā€¢ Finalized plans to deliver post-merger cost synergies ā€¢ Progressed plans for Day One readiness ā€¢ $9.5B Sales (-3% or -1% ex seed sales timing) ā€¢ $1.8B Operating Earnings (+7%) ā€¢ 18% Operating Earnings Margin (+ ~170 bps) 2 0 1 7 P R I O R I T I E S ā€¢ Achieve sales, operating earnings and cash commitments ā€¢ Drive rapid and successful technology launches ā€¢ PioneerĀ® brand soybeans with Roundup Ready 2 XtendĀ®technology ā€¢ LeptraĀ® insect protection & PioneerĀ® brand QromeTM products ā€¢ DuPontTM FeXapanTM herbicide ā€¢ DuPontTM VessaryaTM fungicide ā€¢ DuPontTM LumisenaTM seed treatment ā€¢ Close merger* and execute on integration plans in preparation for intended spin** * Pending satisfaction of customary closing conditions, including receipt of regulatory approval ** Subject to approval of DowDuPont board 3
  • 4. CONSUMER DESIRES REQUIRE INNOVATION IN THE AG INDUSTRY 4 HEALTH & SAFETY KNOWING THE ā€œFOODā€™S STORYā€ LESS FOOD WASTE ā€œFREE FROMā€ FOOD SOURCES ENVIRONMENTAL STEWARDSHIP
  • 5. Food demand grows at a dramatic pace. There is immense pressure to do more with less, and be sustainable. THE NEED FOR CROP PRODUCTIVITY TO MEET CONSUMER DEMAND 5 Must greatly increase production Grain yield must increase to meet demand Farming pressures - climate, pests, pricing Must increase output off arable land Must sustainably manage all resources Increased fuel and emissions standards GLOBAL ARABLE LAND A cres per person* 2014 0.5 2033 0.4 2014 8.5 2033 7.2 WORLD POPULATION In B illions, Estimated Data Source: Census Bureau for population figures and FAO for arable land figure. *Uses 2014 arable land figures for 2033 acres per person calculation
  • 6. 6Source: DuPont Ag Quantitative farmer survey, 2016 (n=1,852, Global responses to date) Growers require sustainable crop productivity and efficiency gains as they navigate multiple challenges. ~ 3/4 of growers ranked ā€œproductivity per acreā€ as their #1 concern INCREASING SEED PERFORMANCE & PRODUCTIVITY OPTIMIZING PROFITABILITY IN ALL MARKET CONDITIONS ENHANCING OUTPUT & FUNCTIONALITY INSECT, WEED, DISEASE & NEMATODE CONTROL AGRONOMIC PERFORMANCE VERSUS OPERATIONAL CONSTRAINTS PRODUCTIVITY CHALLENGES FOR GROWERS
  • 7. 7 Only DuPont can collaborate with growers acre by acre to answer these demands. Everything we do is about solving one problem ā€“ a complex problem that has grown and changed with the needs of our growing world ā€“ C R O P P R O D U C T I V I T Y ā€œWe put a great emphasis in managing our grain on a much more micro level ā€“ so looking not on a field by field basis but more on an acre by acre and even in some cases on a sub-acre level.ā€ - DuPont Customer BIOTECH BREEDING CRISPR SEED APPLIED TECHNOLOGY CROP PROTECTION DIGITAL SOLUTIONS AGRONOMIC SOLUTIONS DUPONTā€™S KEY FOCUS AREAS
  • 8. MULTI-PLATFORM APPROACH TO INCREASING CROP PRODUCTIVITY 8 Corn Soy Canola, Sunflower, & Other Oilseeds Rice Fruits/Veg Other BREEDING CRISPR BIOTECH CROP PROTECTION SEED APPLIED TECHNOLOGY Insect Control* Weed Control Disease Control** Output Traits Yield & Agronomics DIGITAL AGRONOMIC SOLUTIONS INDUSTRY LEADING INNOVATION * Includes nematodes ** Includes bacterial and fungal diseases D I G I T A L
  • 9. GROWER CHALLENGE 1: ADDRESSING FALL ARMYWORM IN LATIN AMERICA 9 KEYSTOPERFORMANCE P O W E R F U L P Y R A M I D P R O T E C T I O N + A B O V E G R O U N D I N S E C T C O N T R O L H I G H P E R F O R M A N C E A C R O S S A L L I N S E C T P R E S S U R E S T R A I T D U R A B I L I T Y E X C E L L E N T E N V I R O N M E N T A L P R O F I L E F L E X I B I L I T Y W I T H L A T E P L A N T I N G U T I L I Z I N G LeptraĀ® insect protection1. PioneerĀ® brand hybrids with LeptraĀ® insect protection help protect against a broad spectrum of insects o Brazilā€™s first 3 discrete traits offering for above ground insect control o Protected by DuPontTM DermacorĀ® seed treatment o ~70% volume growth in Brazil summer season o $1B peak sales target 2. Launched with IPM* program for trait durability and sustainable production 3. Multiple Crop Protection solutions to address issue * Integrated Pest Management Control Hybrid G R O W E R V A L U E K E Y P R O D U C T A P P R O A C H E S BREEDING DIGITAL SOLUTIONSBIOTECH SEED APPLIED TECHNOLOGY CROP PROTECTION AGRONOMIC SOLUTIONS
  • 10. GROWER CHALLENGE 2: DEVELOPING SOLUTIONS FOR ASIAN SOYBEAN RUST (ASR) Vessaryaā„¢ Program Industry standard 10 G R O W E R V A L U E KEYSTOPERFORMANCE T A R G E T I N G B R O A D E S T S O L U T I O N S E T F O R A S R I N B R A Z I L P I P E L I N E F U L L O F N E W N A T I V E A N D B I O T E C H L E A D S A P P L Y I N G C R I S P R - C A S T E C H N O L O G Y T O N A T I V E T R A I T S D E M O N S T A T E D Y I E L D B E N E F I T S A N D D U R A B I L I T Y E N A B L E S I N T E G R A T E D R E S I S T A N C E M A N A G E M E N T 1. VessaryaTM fungicide leads portfolio of crop protection solutions with demonstrated yield benefits o Offers comprehensive solution to control multiple fungal diseases o >$200 million peak sales target 2. DuPontTM AproachĀ® Prima part of recommended ASR regimen 3. Integrated seed research programs deploying native and biotech approaches with flexible deployment o Biotech program for durable, season-long protection o Open innovation within biotech to explore novel MOAs* * Mode of Action U T I L I Z I N G BREEDING DIGITAL SOLUTIONSBIOTECH SEED APPLIED TECHNOLOGY CROP PROTECTION AGRONOMIC SOLUTIONS K E Y P R O D U C T A P P R O A C H E S CRISPR
  • 11. GROWER CHALLENGE 3: ADDRESSING GLYPHOSTATE- RESISTANT WEEDS IN NORTH AMERICA (NA) EnviveĀ® + Glyphosate + FeXapanā„¢ Glyphosate alone 3/15/2017 11 KEYSTOPERFORMANCE M A X I M I Z E D Y I E L D S R E S I S T A N C E M A N A G E M E N T T E C H N O L O G Y P R E S E R V A T I O N L O C A L L Y P R O V E N W E E D C O N T R O L S O L U T I O N S G R O W E R V A L U E 1. PioneerĀ® brand soybeans with Roundup Ready 2 XtendĀ® technology o Powered by DuPont Pioneer AYT 4.0 o Expected to comprise ~45% of NA soybean portfolio by 2018 o >$1B peak sales target 2. FeXapanā„¢ herbicide plus VaporGripā„¢ technology o For use on both soybeans and cotton 3. Vigorous training initiative o Centered on technology stewardship and grower experience 11 BREEDING DIGITAL SOLUTIONSBIOTECH SEED APPLIED TECHNOLOGY CROP PROTECTION AGRONOMIC SOLUTIONS U T I L I Z I N G K E Y P R O D U C T A P P R O A C H E S
  • 12. Aggregate estimated peak sales of pipeline programs ~$20B** PIPELINE POISED TO CONTINUE TO DELIVER SOLUTIONS IN THE NEAR & LONG-TERM 12 *Pending regulatory approvals ** Represents the aggregate estimated peak sales of programs represented on slide; not inclusive of all pipeline programs. RECENT LAUNCHES 2017 2018-19 BEYOND ā€¢ PioneerĀ® brand soybeans with Roundup Ready 2 XtendĀ® technology ā€¢ PioneerĀ® brand hybrids with LeptraĀ® insect protection in Brazil ā€¢ LeptraĀ® insect protection in Argentina ā€¢ Stewarded, limited commercial launch of PioneerĀ® brand QromeTM products ā€¢ PioneerĀ® brand OptimumĀ® GLY canola* ā€¢ Herbicide Tolerant Canola with LibertyLinkĀ® trait ā€¢ Expanded commerciallaunch of QromeTM products ā€¢ Corn & soy insect control ā€¢ Next-gen soybeans ā€¢ OptimumĀ® GLY canola + LibertyLinkĀ® traits ā€¢ Expanded ZorvecTM launch in AP and LA ā€¢ VessaryaTM disease controlin LA ā€¢ LumisenaTM seed treatment ā€¢ PyraxaltTM insect control* ā€¢ ZorvecTM expansion into EMEA* ā€¢ New class of nematicides ā€¢ New MOA - disease control SEEDS & T RAIT S CROP PROTECTION ā€¢ CyazypyrĀ® insect control ā€¢ ZorvecTM disease control ā€¢ DuPontTM LumidermTM, LumiviaTM and DermacorĀ® seed treatment
  • 13. Higher yield with no disruption to the native trait characteristics LEADERSHIP IN BREEDING E L I T E G E R M P L A S M ā€¢ Next-generation breeding technologies delivering 2X increase over historical rate of gain* ā€¢ Improved global integration across wide range of DuPont Pioneer germplasm & crops ā€¢ Driving productivity in marker lab enabling a 10x increase in throughput and a 10x decrease in cost per marker data point** ā€¢ From 2010 to 2016, breeding pipeline increased by 150% in scale and quality FIRST COMMERCIAL HYBRID MANAGED DROUGHT TRIALS MARKER ASSISTED SELECTION AND ANALYTICS BIOTECH TRAIT INTEGRATION GENOMIC PREDICTION CRISPR-CAS E X T E N S I V E G E R M P L A S M L I B R A RY 1926 1957 1995 1998 2009 2016 P R O D U C T I V I T Y 1905 2025 Continued excellence in breeding, increasing genetic diversity, efficiency and quality of product development. BUILDING UPON OVER 90 YEARS OF PLANT BREEDING LEADERSHIP * 100-113 CRM germplasm pipeline **Over ten-year period 13 INFINITE YIELD POSSIBILITIES
  • 14. BROAD AGRICULTURAL APPLICATIONS OF CRISPRNEAR-TERM PRODUCTS TO MARKET NORTHERN CORN LEAF BLIGHT ā€¢ Devastating global disease with potential to cause $1.6B* annual losses in North America alone ā€¢ Leveraging germplasm base ā€¢ Utilizing native genes, genomic selection, and genome editing ā€¢ Providing sustainable grower solutions NORTHERN CORN LEAF BLIGHT READINESS: First half of next decade WAXY CORN HYBRIDS ā€¢ Foundational for future product development ā€¢ First commercial agricultural product ā€¢ To market by end of decade CRISPR genome editing technology for advanced breeding LEADERSHIP IN CRISPR ADVANCED BREEDING TECHNOLOGY Products, benefits and concepts described herein will not be offered for sale or distribution until completion of field testing and applicable regulatory reviews. * Source: Internal analysis and USDA. DISEASE RESISTANCE YIELD & YIELD STABILITY DROUGHT TOLERANCE OUTPUT TRAITS MATURITY CORN ā€¢ ā€¢ ā€¢ ā€¢ SOY ā€¢ ā€¢ ā€¢ CANOLA ā€¢ ā€¢ ā€¢ RICE ā€¢ ā€¢ ā€¢ ā€¢ WHEAT ā€¢ ā€¢ SUNFLOWER ā€¢ ā€¢ 14
  • 15. NORTH AMERICA PIONEERĀ® BRAND CORN 15 D E E P P O R T F O L I O O F C O R N T O C O V E R N O R T H A M E R I C A N P R O D U C T I O N N E E D S ADVANTAGED YIELD PERFORMANCE* C O R N H Y B R I D S P R E S E N T E D I N C H A RT R E P R E S E N T ~50% O F N O RT H A M E R I C A N C O R N V O L U M E <103 C R M 103 ā€“ 113 C RM >113 C R M 0BU/AAdvantage13 H I G H L I G H T S ā€¢ Across over 21,000 competitor comparisons, and across all maturity zones, leader PioneerĀ® brand corn products produce an advantaged yield performance ā€¢ In 2016, ~50% of the North American corn volume was from hybrids released in the last 2 years ā€¢ 2017 portfolio includes 29 new genetic platforms and 53 new products ā€¢ Full breeding pipeline of future products World Record of 532 bu/acre Source: 2016 Pioneer on-farm trial database. Customer comparisons based on 2016 yield results including data from weight wagon and PKP trials for all PioneerĀ® brand hybrids against all competitors. Individual results may vary. All data weighted by comparisons within 4CRM and adjusted to 15% moisture. Products performance is variable and subject to any number of environmental, disease and pest pressures.
  • 16. High-yield performance with proven insect protection PIONEERĀ® BRAND QROMEā„¢ PRODUCTS BREEDING DIGITAL SOLUTIONS U T I L I Z I N G BIOTECH AGRONOMIC SOLUTIONS Q R O M E ā„¢ p r o d u c t s ā€¢ Limited commercial launch in 2017 growing season across Western U.S. Corn Belt* ā€¢ Enables PioneerĀ® brand triple- stack product mix to increase significantly in the next five years ā€¢ Strengthens yield performance in corn rootworm areas ā€¢ Improved integration across a broad range of PioneerĀ® germplasm ā€¢ ~$2B peak sales target YIELD E N H A N C E D Y I E L D P E R F O R M A N C E E X P A N D E D B R E E D I N G A P P L I C A B I L I T Y ELITE PRODUCTS 4 - 7 bu/A INCREASE QROMEā„¢ PRODUCTS 190Yield(bu/A)205 GERMPLASM ELITE PRODUCTS QROMEā„¢ PRODUCTS %OFGERMPLASM COMPATABILITY Source: DuPont Pioneer Research Trials * QromeTN products are approved for cultivation in the U.S. and Canada and have also received import approval in a number of importing countries. DuPont Pioneer continues to pursue additional import approvals for QromeTM products, including in China, in accordance with Excellence Through Stewardship Product Launch Guidance. 16 ~50% INCREASE
  • 17. PIONEERĀ® BRAND A-SERIES SOYBEAN LAUNCH POWERED BY ACCELERATED YIELD TECHNOLOGY 4.0 *Data is based on average of 2016 comparisons made across all major soybean growing areas of the United States through Nov. 29, 2016. Comparisons are against all competitors in Pioneer IMPACTā„¢ plots unless otherwise stated, and within +/-03 RM of the competitive brand. Product responses are variable and subject to any number of environmental, disease and pest pressures. Individual results may vary. Multi-year and multi-location data are a better predictor of future performance. 17 DRAMATIC INCREASE IN SOY VARIETY TESTING VIA ACCELERATED YIELD TECHNOLOGY (AYT 4.0) PIONEER PREDICTIVE BREEDING APPLICABLE FOR ALL CROPS: Use AYT 4.0 to select only those with the best gene combinations for field evaluation. 100,000 2012 2017 2 Million 20x INCREASEā€¢ DuPont Pioneerā€™s highest yielding line of soybean varieties ever ā€¢ Launched 54 new A-Series varieties for 2017, including 30 varieties with Roundup Ready 2 XtendĀ® technology ā€¢ Forecasted to comprise nearly 40% of NA soybean volume by 2018 ā€¢ Generates greater than 2bu/A yield advantage* ā€¢ Leading agronomic package of defense traits to meet local needs FIELD TESTS PER YEAR MOLECULAR MARKER TESTS PER YEAR 0BU/A Advantage <2 R M 2-3 R M >3 R M A-SERIES SOYBEANS WITH ROUNDUP READY 2 XTENDĀ® TECHNOLOGY LEADERS * 8
  • 18. Unmatched knowledge of the customer, global insights and information applied locally enables growers to achieve better performance in the field DUPONT PIONEERā€™S ADVANTAGED ROUTE TO MARKET 18 RI GHT PRODUC T RI GHT ACRE P I O N E E R S A L E S R E P R E S E N T A T I V E S A V A I L A B L E 2 4 / 7 W O R K D I R E C T L Y W I T H G R O W E R F L E X I B L E P R O G R A M S W I N N I N G S T R A T E G Y S P A N S M U L T I P L E R E G I O N S C O N N E C T E D T O L O C A L M A R K E T I S S U E S I N - M A R K E T D E V E L O P M E N T & C O L L A B O R A T I O N C R O P M A N A G E M E N T I N S I G H T S E X C L U S I V E L Y S E L L S P I O N E E R Ā® B R A N D S E E D
  • 19. Provides grower with average gross return of $22 per acre* ENCIRCASM SERVICES 19 Source: 2016 DuPont Pioneer on-farm trials. E N C I R C A S M S E R V I C E S B Y T H E N U M B E R S ADVANTAGE WITH ENCIRCASM NITROGEN SERVICE* YIELD NITROGEN +6 bu/A -8 lbs. ā€œTechnology has played a huge part of our ability to expand productionā€¦ . Weā€™ve seen over the last five years a significant leap in all field yield levels, and I think thatā€™s going to be the number one contributor to us being able to continue to grow and continue to thrive.ā€ - DuPont Grower >75 million acres of operational data 12 million acres advised on product placement 2+ million paid acres $7 average gross revenue per paid acre 67% of the time our recommendation beat the current grower practice* 6 bushel per acre yield advantage* 8 pounds less nitrogen per acre* $22 per acre average grower return* *Source: Data from 420 DuPont Pioneer research trials conducted in 2015 and 2016. Amounts shown are averages based on gross (before service fee) revenue and standardized input and grain market prices.
  • 20. The intersection of crop protection and seed businesses DUPONTā„¢ SEED TREATMENT ENTERPRISE 20 TREATED WITH LUMIDERMTM TREATED WITH DERMACORĀ® TREATED WITH LUMIVIATM TREATED WITH LUMISENATM U T I L I Z I N G DIGITAL SOLUTIONS CROP PROTECTION AGRONOMIC SOLUTIONS SEED APPLIED TECHNOLOGY SEED TREATMENT ENTERPRISE ā€¢ 4 products launched in multiple countries ā€¢ > $400 million peak sales ā€¢ Extensive development and field testing capabilities ā€¢ Continuous testing and selection of pest products to compliment genetics ā€¢ Develop and provide advanced seed applied technologies to improve grower productivity
  • 21. Innovative, game-changing technology: A better crop for a better business DUPONTā„¢ ZORVECā„¢ DISEASE CONTROL 21 *Depending on environmental conditions. Z O R V E C ā„¢ ā€¢ >$200 million peak sales target ā€¢ Launched in over 10 countries ā€¢ European (EU) regulatory acceptance for tech material. Preparing for 2018 large EU launches ā€¢ Enables growers to reduce total costs U T I L I Z I N G Rainfast after 20 minutes Delivers 3 to 4 more days of disease control than the competition, even under high disease pressure* Offers protection of new growth DIGITAL SOLUTIONS AGRONOMIC SOLUTIONS CROP PROTECTION DELIVERING CONSISTENT DISEASE CONTROL
  • 22. The next game changer for insect control in Asia Pacific rice DUPONTā„¢ PYRAXALTā„¢ INSECT CONTROL DuPontTM PyraxaltTM is not registered for use or sale in the United States and other countries. No offer for sale, sale or use of these products are permitted prior to the issuance of the country level registration. 22 P Y R A X A L T ā„¢ ā€¢ Novel activity for control of a wide spectrum of hopper insects in rice ā€¢ New standard for high-potency low-use rate and favorable environmental profile ā€¢ Registration dossiers submitted in key rice countries; first sales in 2018 ā€¢ >$150 million peak sales target PLANT HOPPERS THREATEN 87% OF WORLD RICE PRODUCTION AFFECTED COUNTRIES U T I L I Z I N G DIGITAL SOLUTIONS AGRONOMIC SOLUTIONS CROP PROTECTION H O P P E R B U R N
  • 23. YIELDING RESULTS 23 M E E T I N G G R O W E R S ā€™ N E E D S We customize our products and services to meet the needs of each crop/field/acre ā€¢ enabling higher yield, ā€¢ more consistent results, ā€¢ and better returns. C O N T I N U O U S I N N O V A T I O N By continually innovating, we are able to help growers meet the rising demand ā€¢ sustainably, ā€¢ responsibly, ā€¢ and safely. I M P R O V E D R E T U R N The ability to provide integrated solutions enables us to better meet grower needs while delivering increased productivity and profitability for both the customer and DuPont. 23
  • 24. ā€œOne of the most important things that DuPont has been is an agronomy partner which has been a huge aspect to our growth in production.ā€ ā€“ DuPont Customer 24
  • 25. Copyright Ā© 2017 DuPont or its affiliates. All rights reserved. The DuPont Oval Logo, DuPontā„¢ and all products denoted with ā„¢ or Ā® are registered trademarks or trademarks of E. I. du Pont de Nemours and Company or its affiliates. 25
  • 26. R&D DISCOVERY AND COMMERCIALIZATION PROCESS Discovery ProofofConcept Advanced Development Early Development Pre-launch Launch D 1 2 3 4 L ā€¢ Select product target ā€¢ Identify leads ā€¢ Product Stewardship ā€¢ Crop transformation ā€¢ Demonstrate proof of concept ā€¢ Gene and construct optimization ā€¢ Production transformation ā€¢ Event characterization ā€¢ Event development ā€¢ Initiate regulatory testing ā€¢ Advanced field testing ā€¢ Regulatory testing ā€¢ Regulatory dossier submission ā€¢ Regulatory testing ā€¢ Trait introgression and seed ramp up ā€¢ Pre-marketing ā€¢ IMPACTā„¢ trials ā€¢ Regulatory approvals ā€¢ Commercial sales begin ā€¢ Product stewardship 26
  • 27. CORN BIOTECH PIPELINE 27 CORN R&D PHASE MARKETS (ā—) PRIMARY MARKET OPPORTUNITY (MM ACRES) Est. Peak Sales D 1 2 3 4 L NA EU LA AP AF <50 50-100 >100 H / M / L HIGHLIGHTED PRODUCT CONCEPTS PioneerĀ® brand Qromeā„¢ products ā— H BIOTECH SOLUTIONS New MOA Lepidopteran Protection III ā— ā— ā— ā— New MOA Coleopteran Protection III ā— Yield & Yield Stability ā— LIMITED R&D Phases D = Discovery, 1 = Proof of Concept, 2 = Early Development, 3 = Advanced Development, 4 = Pre-Launch, Launch = Available for commercial sale or use Market Opportunity Market Opportunity reflects total acres in Primary Markets in millions Estimated Peak Sales Range provided for projects Phase 3 or later in pipeline: L = $0-100MM, M = $100-500MM, H = $500MM+ Arrow indicates advancement or addition (2/16-2/17) Products, concepts, or benefits described herein will not be offered for sale or distribution until completion of field testing and applicable regulatory reviews. Each Phase represents only the lead event for each program. Discovery and market evaluation is an ongoing process for all programs in the pipeline.
  • 28. SOYBEAN BIOTECH PIPELINE 28 SOYBEAN R&D PHASE MARKETS (ā—) PRIMARY MARKET OPPORTUNITY (MM ACRES) Est. Peak Sales D 1 2 3 4 L NA EU LA AP AF <50 50-100 >100 H / M / L HIGHLIGHTED PRODUCT CONCEPTS PioneerĀ® brand PlenishĀ® high oleic soybeans^ ā— M Multiple Mode Herbicide Tolerance ā— ā— H BIOTECH SOLUTIONS Increased Soybean Oil & Improved Meal Value ā— ā— Lepidopteran Protection ā— Hemipteran Protection ā— Asian Soybean Rust Resistance ā— R&D Phases D = Discovery, 1 = Proof of Concept, 2 = Early Development, 3 = Advanced Development, 4 = Pre-Launch, Launch = Available for commercial sale or use Market Opportunity Market Opportunity reflects total acres in Primary Markets in millions Estimated Peak Sales Range provided for projects Phase 3 or later in pipeline: L = $0-100MM, M = $100-500MM, H = $500MM+ Arrow indicates advancement or addition (2/16-2/17) Products, concepts, or benefits described herein will not be offered for sale or distribution until completion of field testing and applicable regulatory reviews. Each Phase represents only the lead event for each program. Discovery and market evaluation is an ongoing process for all programs in the pipeline.
  • 29. ADDITIONAL CROPS BIOTECH PIPELINE 29 ADDITIONAL CROPS R & D PHASE MARKETS (ā—) PRIMARY MARKET OPPORTUNITY (MM ACRES) Est. Peak Sales D 1 2 3 4 L NA EU LA AP AF <50 50-100 >100 H / M / L CANOLA OptimumĀ® GLY herbicide tolerance hybrids ā— ā— M Herbicide Tolerant Canola with the LibertyLinkĀ® trait ā— L Herbicide Tolerant Canola with the OptimumĀ® GLY & LibertyLinkĀ® trait stack ā— L R&D Phases D = Discovery, 1 = Proof of Concept, 2 = Early Development, 3 = Advanced Development, 4 = Pre-Launch, Launch = Available for commercial sale or use Market Opportunity Market Opportunity reflects total acres in Primary Markets in millions Estimated Peak Sales Range provided for projects Phase 3 or later in pipeline: L = $0-100MM, M = $100-500MM, H = $500MM+ Arrow indicates advancement or addition (2/16-2/17) Products, concepts, or benefits described herein will not be offered for sale or distribution until completion of field testing and applicable regulatory reviews. Each Phase represents only the lead event for each program. Discovery and market evaluation is an ongoing process for all programs in the pipeline.
  • 30. 30 CROP PROTECTION R&D Phase1 Target Market (Shaded) Estimated Peak Sales 2 D 1 2 3 4 L F&V Rice Cereals Corn Oil Seed WEED CONTROL New class of grass and broad leaf weed control New mode of action grass and broad leaf weed control New class of grass and broad leaf weed control New mode of action grass and broad leaf weed control INSECT and NEMATODE CONTROL New class of insect control for piercing/sucking pests Fluazaindolizine, new mode of action nematicide M Pyraxaltā„¢, new class of insect control for piercing pests M CyazypyrĀ® cross-spectrum insect control M Lumiviaā„¢ Seed Treatment M Lumiposaā„¢ Seed Treatment L DISEASE CONTROL Broad-spectrum disease control, new mode of action Zorvecā„¢ oomycete control, new mode of action M Penthiopyrad broad-spectrum disease control M Lumisenaā„¢ Seed Treatment L CROP PROTECTION PIPELINE New R&D Phases D = Discovery, 1 = Proof of Concept, 2 = Early Development, 3 = Advanced Development, 4 = Pre-Launch, Launch = Available for commercial sale or use Estimated Peak Sales Range provided for projects Phase 3 or later in pipeline: L = $0-100MM, M = $100-500MM, H = $500MM+ Arrow indicates advancement or addition (2/16-2/17) Products, concepts, or benefits described herein will not be offered for sale or distribution until completion of field testing and applicable regulatory reviews. Each Phase represents only the lead event for each program. Discovery and market evaluation is an ongoing process for all programs in the pipeline. New
  • 31. AgrisureĀ® and Agrisure VipteraĀ® are registered trademarks of, and used under license from, a Syngenta Group Company. AgrisureĀ® technology incorporated into these seeds is commercialized under a license from Syngenta Crop Protection AG. HerculexĀ® Insect Protection technology by Dow AgroSciences and Pioneer Hi-Bred. HerculexĀ® and the HX logo are registered trademarks of Dow AgroSciences LLC. LibertyĀ®, LibertyLinkĀ® , and the Water Droplet Design are registered trademarks of Bayer. YieldGardĀ®, the YieldGard Corn Borer design, and Roundup ReadyĀ® are trademarks of Monsanto Technology LLC used under license. DO NOT APPLY DICAMBA HERBICIDE IN-CROP TO SOYBEANS WITH Roundup Ready 2 XtendĀ® technology unless you use a dicamba herbicide product that is specifically labeled for that use in the location where you intend to make the application. IT IS A VIOLATION OF FEDERAL AND STATE LAW TO MAKE AN IN-CROP APPLICATION OF ANY DICAMBA HERBICIDE PRODUCT ON SOYBEANS WITH Roundup Ready 2 XtendĀ® technology, OR ANY OTHER PESTICIDE APPLICATION, UNLESS THE PRODUCT LABELING SPECIFICALLY AUTHORIZES THE USE. Contact the U.S. EPA and your state pesticide regulatory agency with any questions about the approval status of dicamba herbicide products for in-crop use with soybeans with Roundup Ready 2 XtendĀ® technology. ALWAYS READ AND FOLLOW PESTICIDE LABEL DIRECTIONS. Soybeans with Roundup Ready 2 XtendĀ® technology contain genes that confer tolerance to glyphosate and dicamba. Glyphosate herbicides will kill crops that are not tolerant to glyphosate. Dicamba will kill crops that are not tolerant to dicamba. Roundup Ready 2 XtendĀ®, and VaporGripā„¢ are trademarks of Monsanto Technology LLC used under license. Pioneer is a member of Excellence Through StewardshipĀ® (ETS). Pioneer products are commercialized in accordance with ETS Product Launch Stewardship Guidance and in compliance with the Pioneer policies regarding stewardship of those products. Crops and materials containing biotech traits may only be exported to or used, processed, or sold in jurisdictions where all necessary regulatory approvals have been granted for those crops and materials. It is a violation of national and international laws to move materials containing biotech traits across borders into jurisdictions where their import is not permitted. Growers should discuss these issues with their purchaser or grain handler to confirm the purchaser or handlerā€™s position on products being purchased. Excellence Through StewardshipĀ® is a registered trademark of the Biotechnology Industry Organization. ^ EXPORT APPROVAL NOTICE: These products are authorized for planting in the United States and Canada. While many import market authorizations are in place, grain and byproducts produced from grain containing this technology may not be authorized in some markets. Growers that use this product are required and agree to adhere to the stewardship requirements as outlined in the Pioneer Product Use Guide and product-specific stewardship requirements for this product. For questions regarding product stewardship and biotech traits, please contact your sales representative or refer to www.pioneer.com/stewardship. Growers are required to discuss trait acceptance and grain purchasing policies with their local grain handler prior to delivering grain containing biotech traits. QromeTM products are approved for cultivation in the U.S. and Canada and have also received import approval in a number of importing countries. DuPont Pioneer continues to pursue additional import approvals for QromeTM products, including in China, in accordance with Excellence Through Stewardship Product Launch Guidance. EncircaSM services are provided subject to the terms and conditions of purchase which are part of the purchase documents. EncircaSM services provides estimates and management suggestions based on statistical and agronomic models. EncircaSM services is not a substitute for sound field monitoring and management practices. Individual results may vary and are subject to a variety of factors, including weather, disease and pest pressure, soil type and management practices. Ā®, SM, TM Trademarks and service marks of DuPont, Pioneer or their respective owners. Ā© 2017 PHII. PioneerĀ® brand products are provided subject to the terms and conditions of purchase which are part of the labeling and purchase documents. ^ 31Updated as of March 15, 2017 to incorporate Pioneer branding.