Social Awareness and Treatment Strategies of COVID-19 which is very essential to know everyone.

1. Social Awareness and Treatment Strategies of COVID-19
Presented By
Debolina Saha*, Ms. Jeenatara Begum
*Guru Nanak Institute of Pharmaceutical Science and Technology
157/F, Nilgunj Road, Panihati, Kolkata – 700114, West Bengal , India
Email id : debolinasaha83@gmail.com
Introduction:
COVID-19 is a new health crisis which threatening the world with the emergence and spread of severe acute respiratory syndrome corona virus 2 (SARS-CoV2). This new corona
virus (SARS-COV-2) started as a local outbreak in Wuhan, China but soon broke out through all over the world. According to the World Health Organization (WHO) SARS-CoV
in 2002to 2003 and H1N1 influenza in 2009 and in 2012 Middle East respiratory syndrome corona virus (MERS) have been recorded. The first case was reported on 31st
December in 2019 in WHO country office in China. On 11th February 2020 WHO declared this virus as COVID-19. The disease is spread through respiratory droplets by
coughing and sneezing or by touching our nose and mouth after touching any contaminated surface. .For the treatment of COVID-19 Lopinavir, Ribavarin, Chloroquine or
Hydroxycholoroquine , Methyprednisolone e.t.c drugs as well as plasma therapy have been used. Favipiravir, Remdesivir and Covaxin e.t.c. newly discovered drugs which are
under clinical trial 1.
•Fever
•Cough
•Sneezing
•Sore throat
Symptoms of COVID -19 2:
Severe symptoms
•Kidney failure
•High fever
•Pneumonia
•Death Fig 2. Symptoms of COVID-19
Common symptoms
Fig 1: SARS CoV 24
Transmission of COVID-19 Disease3:
•Coughing or sneezing from infected person.
•Touching contaminated objects
•Touching your face, eyes and nose after touching
contaminated surface. Fig 3: Transmission from
infected person
Fig 4: Transmission from
coughing5
Fig 5: Contamination from
touching
eyes, face e.t.c.
Fig 6: Wash
your hands
Fig 7:Avoid
handshake
Fig 8:Keep minimum 2 mt
distance from infected person.
Fig 9:Cover your nose
and mouth with mask.7
Fig10 :Stay
safe at home
Fig 11: Clean often touched
surfaces with disinfectants.
Fig 12: Use sanitizer or 70%
alcohol based solution.
Social awareness to prevent COVID-196
Treatment Strategies of COVID-198 :
Scientist are trying to make new medicine and test some existing drug to see whether they can treat COVID-19. In the mean time there are a number of things that can relieve both at home and at
hospitals. Scientists are already developed few drugs for COVID-19 treatment which are under clinical trial. Some vaccines are also developed like Remdesivir , Covaxine e.t.c. Plasma therapy plays
a important role in COVID-19 management.
 Table 1: Drugs used in treatment of COVID-19 :
Drug Dosage Form Company Class of Drug Status Mechanism of action Disease Condition
Remdesivir9 Intravenous (i.v.),
Inhaler
Gilead Antiviral Approved Inhibit replication Moderate
Favipiravir Oral tablet Glenmark Antiviral Approved Inhibiting replication by inhibiting RNA polymerase Mild to moderate
Hydroxychloroquine10 Oral tablet Bengal Chemical Anti-malarial Approved Decreases the acidity of endosomes, which are
compartments inside cells that some viruses co-opt to
enter cells and cause infection
Prophylaxis condition
Health and frontline worker,
Mild condition
Tocilizumab Intravenous drip Genentech Monoclonal antibody Approved Acting against cytokine storm Moderate to severe
Dexamethasone i.v ( ICU patients) ,
Oral tablet
Zydus, Cadlia Corticosteroid Not approved for
COVID-19
Given to severely ill patients on invasive ventilation or
oxygenation
Adjuvant
Convalescent Plasma11 Transfusion Blood bank Plasma therapy Approved Infection-fighting antibodies from the blood of
recovered people given to ill patient to boost their
immunity
Moderate condition,
Oxygen requirement
Glucocorticoids parenteral Uniroyal Biotech Corticosteroids Approved Calms acute inflammatory response to slow disease
progression by preventing the body from pumping out
inflammatory chemicals
Severely ill patients with
progressively deterioration
Covaxin12 Parenteral Bharat Biotech Vaccine (Antiviral) Human trial Increase immunity as a vaccine Vaccination
 Table 2 :Update about COVID-19 Patient (Till 8.43 a.m 6th July,2020)13
Country
& other
Total
Cases
New
Cases
Total
Death
Recovered
Cases
World 11,572,479 +21,934 +604 6,543,078
USA 2,983,142 +214 +2 1,289,687
Brazil 1,604,585 978,615
India 698,817 +981 +7 424,963
Russia 687,862 +6611 +135 454,329
Peru 302,718 193,957
0
2,000,000
4,000,000
6,000,000
8,000,000
10,000,000
12,000,000
World
USA
Brazil
India
Russia
Peru
Total Cases New Cases Total Death Recovered Cases
Graphical representation of Update about COVID-19 Patient (Till 8.43 am 6th July,2020 )Conclusions:
This new virus outbreak
has challenged the
economic, medical and
public health infrastructure
of China and to some
extent, of other countries
especially, its neighbors.
Time alone will tell how
the virus will impact our
lives here in India. If every
prevention and awareness
are maintained then it can
be prevented . Many drugs
are already marketed . So it
can be said that our world
will recover shortly from
this crucial period. 14
References:
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