Trauma Cart Contents
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This document provides an inventory of the contents of a trauma cart organized into different drawers labeled for different emergency needs: airway, breathing, circulation. The top drawer contains basic supplies like sutures, staplers, and sterile dressings. The second drawer holds tracheostomy tubes and supplies. The third drawer contains chest tube kits and describes the new disposable chest tube tray contents. The fourth drawer has a thoracotomy tray and circulatory supplies. The fifth drawer holds Cordis catheters. The bottom drawer stores lap pads and towels. Gloves, masks, and gowns are kept on the side of the cart.
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Endocrine Therapy
Endocrine therapy is the cornerstone of treatment for HR+ breast cancer in postmenopausal women. The primary goal is to reduce the levels of estrogen or block its effects on cancer cells. Commonly used agents include:
Selective Estrogen Receptor Modulators (SERMs): Tamoxifen is a SERM that binds to estrogen receptors, blocking estrogen from stimulating breast cancer cells. It is effective but may have side effects such as increased risk of endometrial cancer and thromboembolic events.
Aromatase Inhibitors (AIs): These drugs, including anastrozole, letrozole, and exemestane, lower estrogen levels by inhibiting the aromatase enzyme, which converts androgens to estrogen in peripheral tissues. AIs are generally preferred in postmenopausal women due to their efficacy and safety profile compared to tamoxifen.
Selective Estrogen Receptor Downregulators (SERDs): Fulvestrant is a SERD that degrades estrogen receptors and is used in cases where resistance to other endocrine therapies develops.
Combination Therapies
Combining endocrine therapy with other treatments enhances efficacy. Examples include:
Endocrine Therapy with CDK4/6 Inhibitors: Palbociclib, ribociclib, and abemaciclib are CDK4/6 inhibitors that, when combined with endocrine therapy, significantly improve progression-free survival in advanced HR+ breast cancer.
Endocrine Therapy with mTOR Inhibitors: Everolimus, an mTOR inhibitor, can be added to endocrine therapy for patients who have developed resistance to aromatase inhibitors.
Chemotherapy
Chemotherapy is generally reserved for patients with high-risk features, such as large tumor size, high-grade histology, or extensive lymph node involvement. Regimens often include anthracyclines and taxanes.
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* ChatGPT and OpenAI belong to OpenAI, L.L.C.
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- 2. Top Drawer Raney Clips Tape Paperclips Sterile 4x4 Suture kit 2-0 prolene 3-0 prolene Soon to be 0 prolene Raney clip clamp Stapler #10 and #15 blades Betadine
- 3. 2nd Drawer – “A” for airway Tracheostomy tubes Tracheostomy tray (we will soon have a disposable tray that will minimize instruments) Yankauer
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- 5. What is in the new disposable CHEST TUBE tray? I thought you’d never ask… #11 blade x 2 0 Silk suture x 2 Betadine prep sticks Vaseline gauze Sterile gauze Blue towels Instruments: Scissors x 2 Needle holder Straight hemostat x 1 Curved Hemostat x 2 10” Forcep clamp x 2 Forcep
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- 7. 5th Drawer – “C” continued (Cordis catheters)
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