Cannabis and Autism - Dr Christian Bogner, MD
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My presentation to the Aaps Meeting and Exposition in Denver, CO 10/16/16 about my findings on the primary cause of disordered endocannabinoid tone from neurotoxins such as glyphosate and how this plays with pathophysiology in autism spectrum disorders.
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Cannabis and Autism - Dr Christian Bogner, MD
- 1. Autism & Cannabis Christian Bogner, MD Denver, Colorado 2016
- 2. DECLARATION • There is no conflict of interest in this lecture • I received no monetary benefit from this lecture • No implied sponsorship by any company to the speaker • No affiliation with the pharmaceutical or cannabis industry • All patients in this presentation had an informed consent for photography and publication
- 3. AUTISM TREATMENT WITH CANNABIS • I will not speak about • Dosage recommendations • Ratios • Strains
- 4. AUTISM TREATMENT WITH CANNABIS • I will speak about • Primary cause of disordered endocannabinoid tone: neurotoxins • Endocannabinoid pathophysiology in autism spectrum disorders
- 5. AUTISM FACTS -70% of the children with ASD have GI Issues compared to 42% of the children with developmental disorder other than ASD -Toxic overload (aluminum, mercury, copper) -Vitamin D deficiency -Systemic Inflammation
- 6. AUTISM Known facts -70% of the children with ASD have GI Issues compared to 42% of the children with developmental disorder other than ASD -Toxic overload (aluminum, mercury, copper) -Vitamin D deficiency -Systemic Inflammation WHAT CAUSES THIS ?
- 11. GLYPHOSATE • Enzyme inhibitor • Antifungal agent • Herbicide • Uncoupling agent -National Center for Biotechnology Information
- 12. GLYPHOSATE -Glycine [a potent neurotransmitter / non-essential amino acid] -Formaldehyde [known neurotoxin affecting memory,learning,behavior] -Phosphorous Acid [white phosphorous used in chemical warfare] -Ullmann's Encyclopedia of Industrial Chemistry 7th ed
- 13. GLYPHOSATE pH (1% solution in water) 2.5. EPA: excretion of glyphosate is Feces (~70%) and Kidneys (~30%) -Ullmann's Encyclopedia of Industrial Chemistry 7th ed
- 15. GLYPHOSATE STUDIES • "Despite its relatively benign reputation, Roundup was among the most toxic herbicides and insecticides tested.” - University of Caen, Institute of Biology, Paris, France • "Case control studies in the USA, Canada and Sweden reported increased risk for NHL (Non-Hodgkin's lymphoma) associated with exposure to glyphosate. -International Agency for Research on Cancer, World Health Organization [WHO]
- 16. GLYPHOSATE GI TRACT • "Taken together, these data suggest that Roundup exposure may affect human reproduction and fetal development in case of contamination." -University of Caen, Institute of Biology, Paris, France • . Ingestion of >85 mL of the concentrated formulation is likely to cause significant toxicity in adults. Gastrointestinal corrosive effects. Renal and hepatic impairment are also frequent and usually reflect reduced organ perfusion. -Bradberry SM et al; Toxicol Rev 23 (3): 159-67 (2004)
- 17. GLYPHOSATE GI TRACT • Effects at 30,000 ppm included central lobular hepatocyte hypertrophy in males, central lobular hepatocyte necrosis in males, chronic interstitial nephritis in males, and proximal tubule epithelial basophilia and hypertrophy in females. -California Environmental Protection Agency/Department of Pesticide Regulation • The results/ suggest that acute toxicity at lethal doses may occur as a result of the uncoupling of oxidative phosphorylation. -WHO/International Programme on Chemical Safety; Environmental Health Criteria 159, Glyphosate, (1994).
- 18. GLYPHOSATE GI TRACT • "...in a long term combined study of toxicity and carcinogenicity in rats given glyphosate at normal doses, inflammation was observed in the stomach mucosa..." -International Agency for Research on Cancer, World Health Organization
- 19. GLYPHOSATE BRAIN • Taken together, these results demonstrated that Roundup might lead to excessive extracellular glutamate levels and consequently to glutamate excitotoxicity and oxidative stress in rat hippocampus. -Cattani D et al; Toxicology 320: 34-45 (2014)
- 20. GLYPHOSATE ENDOCRINE • The study tested the effects of glyphosate and Roundup at lower nontoxic concentrations on aromatase, the enzyme responsible for estrogen synthesis. The glyphosate-based herbicide disrupts aromatase activity and mRNA levels... -Richard S et al; Environ Health Perspect 113 (6): 716-20 (2005)]
- 21. GLYPHOSATE GENOTOXICITY • Glyphosate also caused DNA and chromosomal damage in human cells […] one study in community residents reported increases in blood markers of chromosomal damage (micronuclei) after glyphosate formulations were sprayed nearby. -WHO; IARC Monographs Volume 112: evaluation of five organophosphate insecticides and herbicides (March 20, 2015)
- 22. GLYPHOSATE MORE • Roundup exposure may affect human reproduction and fetal development in case of contamination [1] • Glyphosate is toxic to human placental JEG3 cells within 18 hr with concentrations lower than those found with agricultural use [2] • Maternal exposure to glyphosate disturbed the masculinization process in the offsping and promoted behavioral changes and histological and endocrine problems in reproductive parameters [3] • Roundup […] could contribute to Sertoli cell disruption in spermatogenesis that could have an impact on male fertility [4]
- 23. EPA STATEMENT • “Given increased public interest in glyphosate, EPA may recommend sampling for glyphosate in the future”. – Environmental Protection Agency, 2015
- 27. GLYPHOSATE EFFECTS • Oral glyphosate • Destruction of gastrointestinal bacteria via Shikimate pathway disruption • Malabsorption of tyrosine, tryptophan, phenylalanine • Gastrointestinal inflammation and leaky gut • Systemic absorption of protein • Systemic inflammation • Liver P450 enzyme destruction Stephanie Seneff, Senior Research Scientist,MIT
- 31. 170 PPB GLYPHOSATE IN ENFAMIL PROSOBEE LIQUID CONCENTRATE SENEFF, SAMSEL, GLYPHOSATE, PATHWAYS TO MODERN DISEASES III: MANGANESE, NEUROLOGICAL DISEASES, AND ASSOCIATED PATHOLOGIES
- 35. VACCINES
- 36. VACCINES
- 37. MMR VACCINE
- 38. FROM GLYPHOSATE TO AUTISM
- 41. FOODBABE.COM
- 44. Picture by Dr. Hagmeyer
- 45. MOLECULAR EVIDENCE OF BRAIN INJURY
- 52. Glutamate
- 54. AUTISM BRAIN
- 59. Accelerated and abnormal brain growth in the Autistic MSG Used to Trigger Epileptic Seizures MSG Used to Trigger CNS and Brain Damage MSG Used to Damage Eye Cells in Vivo and in Vitro
- 64. IN 1949 DR. MALHERBE TESTED A GROUP OF MENTALLY DISABLED CHILDREN TO SEE IF GLUTAMATE WOULD IMPROVE THEIR MENTAL CAPACITY. IT MADE THEM WORSE.
- 67. WHERE CAN WE FIND MASSIVE AMOUNT OF GLUTAMATE ?
- 73. WHY CBD IS NEEDED
- 74. US patent 6630507 US department of Health and Human Services ‘Cannabinoids as antioxidants and neuroprotectants’
- 75. ‘Cannabinoids have been found to have antioxidant properties, unrelated to NMDA receptor antagonism’
- 76. "In the presence of glutamate alone, and in the presence of glutamate and cannabidiol (CBD) or THC, it was demonstrated that CBD and THC were similarly protective."
- 79. THE CASE FOR THC
- 80. • Endocannabinoid system • Memory consolidation • Memory Extinction
- 81. • Disrupt aspects of short- term (i.e. working) memory • Leave retrieval of well- learned information (i.e. long-term or reference memory) largely intact. CB1 AGONISTS -Cannabinoids as Therapeutics, Mechoulam ECS REFRESHER
- 82. • Disrupt aspects of short- term (i.e. working) memory • Leave retrieval of well- learned information (i.e. long-term or reference memory) largely intact. CB1 AGONISTS • Attentional mechanisms • Associational processes • Consolidation processes • Encoding processes • Retrieval processes
- 83. SKYWALKER Endocannabinoids, phytocannabinoids and synthetic cannabinoids effects on memory
- 85. CONDITIONAL DISCRIMINATION AUDITORY OR VISUAL STIMULUS (KNOWN) REFERENCE (LONG TERM) MEMORY
- 86. CONDITIONAL DISCRIMINATION AUDITORY OR VISUAL STIMULUS (UNKNOWN) WORKING (SHORT TERM) MEMORY
- 90. CONDITIONAL DISCRIMINATION WORKING (SHORT TERM) MEMORY
- 91. CONDITIONAL DISCRIMINATION WORKING (SHORT TERM) MEMORY SR-141716
- 92. CONDITIONAL DISCRIMINATION WORKING (SHORT TERM) MEMORY METHANANDAMIDE
- 93. CONDITIONAL DISCRIMINATION WORKING (SHORT TERM) MEMORY ESTROGEN
- 94. CONDITIONAL DISCRIMINATION WORKING (SHORT TERM) MEMORY ESTROGEN AUTISM BOYS 4.5 : 1 GIRLS
- 95. RELEVANCE • Without proper short term memory, long term memory formation is impaired • It would make sense that repetitive CB1 stimulation would cause the desired effect,e.g. with ABA therapy? Unfortunately, often limited to no effect in severe autism !
- 98. GLYPHOSATE VS BRAIN P450
- 99. BRAIN CYTOCHROME P450 D6 [CYP2D6] - Metabolizes many psychoactive compounds in the brain • implicated in neurodegeneration, psychosis, schizophrenia, and personality traits - involved in the oxidation of 20-30% of the most commonly prescribed drugs
- 100. BRAIN CYTOCHROME P450D6 • Endocannabinoid anandamide is metabolized by CYP2D6, resulting in the formation of multiple mono- and deoxygenated products • Oxidation of anandamide may result in the formation of novel signaling mediators
- 101. BRAIN • Increase in CYP2D6 in 13 different brain regions of alcoholics including the frontal cortex temporal cortex hippocampus substantia nigra all of which are areas of high CB1 expression and where anandamide is known to be produced.
- 103. P450D6 ANANDAMIDE 5,6EET-EAs CB1 CB2 During inflammation upregulated in 13 different brain regions (e.g.alcoholics)
- 104. P450D6 ANANDAMIDE 5,6EET-EAs CB1 CB2 300 fold selectivity 1000 fold affinity
- 105. CB2 receptors on Microglia [brain macrophages]
- 106. CYP2D6 ANANDAMIDE 5,6EET-EAs CB1 300 fold selectivity 1000 fold affinity
- 109. ‘Cannabinoids have been found to have antioxidant properties, unrelated to NMDA receptor antagonism’
- 110. CB2 receptors on Microglia [brain macrophages] Also have TRVP receptors that CB2 activate
- 114. GCMAF – 85% IMPROVEMENT IN AUTISM
- 115. GCMAF – 85% IMPROVEMENT IN AUTISM
- 116. GCMAF P450 Activated vitamin D GCMAF Vitamin D3
- 117. GCMAF P450 Activated vitamin D GCMAF Vitamin D3 glyphosate
- 118. GCMAF P450 Activated vitamin D GCMAF Vitamin D3 glyphosate
- 119. BRADSTREET FAMILY REVELATION ‘85% IMPROVEMENT WITH CANNABIS ONLY’ IMPOSSIBLE TO PROFIT IN U.S. MARKET ?DATA OMITTED?
- 120. SUMMARY Protect brain from further toxic injury – THC/CBD OIL Restore the gastrointestinal system – PROBIOTICS Proper testing Proper education Proper diet (non-GMO, organic) Share information
- 121. THE FUTURE OF AUTISM
- 122. GCMAF P450 Activated vitamin D GCMAF Vitamin D3 glyphosate
- 123. GCMAF P450 Activated vitamin D GCMAF Vitamin D3
- 124. www.mammausa.org
- 125. http://uf4a.org/ The Unconventional Foundation for Autism
- 126. www.drbogner.com
Editor's Notes
- So let’s talk about autism
- So let’s talk about autism
- A vocal minority of experts believes that glyphosate may be much more toxic than is claimed, although the effects are only apparent after a considerable time lapse. Thus, while short-term studies in rodents have shown no apparent toxicity, studies involving life-long exposure in rodents have demonstrated liver and kidney dysfunction and a greatly increased risk of cancer, with shortened lifespan
- I don’t believe anyone knows more about this chemical than Stephanie, who dedicated her life towards educating the world about it. We have spoken for hours trying to merge our understanding about its complex interactions of glyphosate with our human ecosystem.
- This graph shows autism rates since Glyphosate hit the market hard in 1997 when they added GMO soybeans and a year later in 1998 with GMO corn. In the 1980s about 1:2000 kids were autistic. Today it is 1:68. I will show you that this is certainly not because of better diagnostic methodology. Correlation does NOT necessarily reflect causation, but it certainly is an interesting chart.
- Round ups chemical name is N-phophonomethyl glycine
- Synthesized by heating a mixture containing:
- Synthesized by heating a mixture containing:
- This is a white shrimp. To give you an idea about how toxic glyphosate is even in small doses.
- Research demonstrates that 5.2ppm of glyphosate kills him dead.
- I know we humans are more evolved than shrimp, but I hope can start to see how powerful and toxic of a chemical we are talking about. With over half a million “reported” pregnancy losses before 20 weeks in this country every year you start to wonder why 16 developed countries have up to one third less fetal losses.
- More than 90% of corn and soy are genetically modified. They are modified for a specific reason, and that is so you can spray tons of pesticides on them, giving you higher yields and more profit.
- So 80% of parents in the US use formula like this at age 6 months of their newborn according to the CDC. All products tested positive for Monsanto’s genetically engineered soy that is engineered to tolerate spraying with the herbicide glyphosate
- Enfamil’s prosobee liquid tested 170ppb
- Only 18/100 women breastfeed their children. In the first ever testing on glyphosate herbicide in the breast milk of American women, Moms Across America and Sustainable Pulse have found ‘high’ levels of glyphosate in 3 out of the 10 samples tested.
- So I have never released this data and today is the first day. We have sent in PNV to my good friend Bruce Hemming at Microbe Inotech.
- Sure enough, regardless of amount, it was in there.
- Buckle up for this final journey now. With everything you have learned I will take you through on a journey.
- So with all this exposure
- In 1983 10 vaccines were given in early childhood with an autism rate of 1:10,000 Today it’s 1:56 with 46 vaccines
- So let’s see what happens when the babies bodies get exposed to glyphosate.
- The Head of Medical Research at Autism Speaks Paul Wang comments: “Data from our Autism Treatment Network and other research groups have long shown that GI problems such as constipation, diarrhea, abdominal pain and esophagitis are very common among children with autism. This new research provides strong evidence that IBD is likewise more common in children with autism than in other children. This data was collected from around 62,000 patients affected with autism nationwide.
- So the problem is that this creates “leaky gut”, where this “junctions” are bigger, and you will start absorbing bigger proteins, causing immune problems. Why ? Because your body is not supposed to absorb protein.
- In our brains, each neuron fires (on average) about 200 times per second.
- Each time a neuron fires a signal, 1,000 other neurons get that information.
- With 100 billion neurons in our brains and 200 firings per second to 1,000 other neurons, we have 20 quadrillion bits of information transmitted per second in your brain. That is a 2 with 16 zeros behind it.
- So if you decide to wiggle your toes, an impulse must be generated in your brain and that impulse needs fuel, meaning you need to have what we call a neurotransmitter. One of those neurotransmitters that is exciting a nerve cell and creates the impulse is called GLUTAMATE
- SO here you see a picture of a neuron that is ready to fire at any moment. Glutamate is stored here and will be relased in a nano fraction of a second into the synapse and activate the glutamate receptor of the next brain cell.
- But you need TWO messengers to activate a brain cell next to glutamate…and that is GLYCINE. Both of them are produced by your body, so they are absolutely not needed in your diet. They are hence called NON essential amino acids.
- So could glutamate alone stimulate your brain cell ? No, you basically need 2 keys to unlock the door. You actually need TWO messengers to activate a brain cell next to glutamate…
- and that is GLYCINE. Both of them are produced by your body, so they are absolutely not needed in your diet. They are hence called NON essential amino acids.
- Round ups chemical name is N-phophonomethyl glycine
- So let us assume you preconditioned your child with GMO formula, then you continue with poor diet choices. This chronically bathes the brain in pesticides…in theory, the worse the diet, the higher the brain exposure
- So now what is up with the glutamate
- There is a nice paper that was written by John Erb in 2006 that talks about the dangers of MSG. MSG is simply glutamate bound to salt, to make it more stable. And in his report that he handed to the united nations, he demonstrates hundreds of studies that showed how dangerous this chemical really is.
- There is about 3,000 research papers that use MSG as a routine testing chemical to induce seizures, obesity, induce CNS and brain damage. There is also studies that show that there is accelerated and abnormal brain growth in autistic children. That would explain why we have such a wide spectrum in autism and why studies show that the brains of autistics weigh more than average and why so many autistic patients have evidence of seizure disorders.
- Is it that there is certain areas of the brain accelerating already in utero… So we have a garden variety of patients on the spectrum. From severe autism to savant. Kim Peek who is the real life rain man is able to read the left and right page of a book at the same time within a short time and retain about 98% of its information permanently, but he does not know how to brush his teeth. Einstein was a genius with mathematical theories revolutionizing our understanding in physics and the universe, but he also was considered a slow learner and spoke very slowly when he was young.
- So, a lot of children, we said 80% are formula fed. Obviously not all of them become autistic. The numbers are definitely exploding….but what is it that really pushes them into autism ? Your body certainly is smart enough to not produce this in enough to cause problems. Otherwise all children who have high glyphosate exposure have autism.
- Let’s look at the foods that are loaded with glutamate…Soups, frozen foods, baby formula, sweetened juices, cereals, cooking oils, meat, tofu, milk, pop
- Other names and sources of glutamate. It is hard to avoid, especially when you wouldn’t expect it to be in NATURAL beef flavoring.
- So I propose yes…maybe a little excess will be there from the diet
- And that is why we see more ADHD, which in my opinion is clearly a condition that can be very easily cured with the proper dietary modifications.
- GLUTAMATE is placed in vaccines so the live attenuated virus in the MMR vaccine can feed off it and you can put it on a shelf.. So it is a preservative so to say, just to keep the virus alive.The higher the concentration, the higher the shelf life, the more profit the pharma company makes. Easy as that.
- So you get injected. And remember, when you inject something, you bypass the liver.
- The results are neurons firing left and right, up and down. They are firing into a random directions. They do not connect, they literally burn out
- In this movie the apparent data that was omitted was data about African American children who got vaccinated with MMR, showing there was a significant association. Now the movie is amazing, since we have a recording of a senior CDC scientist who was part of this study. But how could anyone explain the higher risk with African americans ?
- In my opinion, this is the reason. Poverty. Higher poverty in African americans. Higher poverty is associated with worse diets. By worse diet I mean diets that are higher in GMOs. Higher GMOs mean higher glyphosate. I can’t proof it. But it makes sense.
- Patent 6630507 is a government patent that was filed by the Department of health and human services. It is titled Cannabinoids as antioxidants and neuroprotectants
- ‘Cannabinoids have been found to have antioxidant properties, unrelated to NMDA receptor antagonism’
- "In the presence of glutamate alone, and in the presence of glutamate and cannabidiol (CBD) or THC, it was demonstrated that CBD and THC were similarly protective."
- This is how you can imagine cannabis works. It blocks the neurons from being exposed to these toxins.
- But it does not block your communication systems, leaving endocannabinoid tone alone. So the solution seems simple….cannabis at the beginning, and avoidance of these toxins.
- I know there is concern about THC psychoactivity and concerns for exposure to the developing brain. Let’s look at this.
- Recent behavioral evidence indicates that the endocannabinoid system modulates key components of learning and memory, which include memory consolidation and extinction. On the molecular level, endocannabinoids have been demonstrated to modulate electrophysiological correlates of learning, suggesting that they play an important role in synaptic plasticity.
- The most consistent delineation made regarding the effects of CB1 agonists is that they tend to disrupt aspects of short-term (i.e. working) memory, while leaving retrieval of well-learned information (i.e. long-term or reference memory) largely intact.
- the term working memory encompasses many distinct processes, including attentional mechanisms, as well as associational, consolidation, encoding and retrieval processes. The endocannabinoid system may play selective roles in different components of memory, as well as in different types of memory.
- So let’s do an experiment to give you an idea of some endocannabinoids, phytocannabinoids and synthetic cannabinoids on memory.
- In this experiment called CONDITIONAL DISCRIMINATION we test both, the SHORT TERM (e.g. working) and LONG TERM (e.g. reference) memory on Skywalker
- Skywalker presses the right lever in the presence of an auditory or visual stimulus to test LONG term memory (or let’s call it REFERENCE memory)
- If Skywalker sees or hears a stimulus he never experienced before, he will press the left lever, because it was a non matching stimulus– a test of working (short term) memory.
- So what do we crazy scientists do ?
- we give Skywalker some pot. And because he is a good sport, we give him
- some cool shades.
- So we have learned that by activating CB1 we created selective deficits in short term memory formation
- Interestingly this was reversed by the compound you see here. SR-141716, which is a CB1-receptor antagonist.
- Interesting to say the least in my opinion is the understanding, however, that this compound “METHANANDANIDE” did the same. this compound is an irreversible CB1 agonist. Think about this. We learned that THC creates short term memory disruptions, but if you dock onto CB1 and basically sit on the receptor without getting eaten by the degradation enzymes, you actually have short term memory restored.
- Fascinating is that Estrogen has been shown to do the same thing. Estrogen improves response accuracy and attenuates the disruptive effects of delta9-THC, which was beautifully demonstrated by Professor Moerschbaecher at LSU.
- Could this explain why boys are affected about 4.5x more affected boys than girls with autism? If you have a better explanation, please email me. The reason I mentioned this study will become very, very important in a second when I will try to explain to you what else is going on in autism.
- Stephanie Seneff demonstrated how glyphosate damaged the P450 microsomal enzymes in the liver via oral ingestion in 2013
- This year Zen Honeycutt released her findings about childhood vaccinations. It is in every vaccine that you can think of, again especially high in MMR
- Which when you think about how you inject it and bypass the liver it is only common sense you will get easy brain access. And this will be taking 10 more minutes, please stay with me and see what is happening here.
- The involvement of certain P450 enzymes in oxidizing AEA and 2-AG was demonstrated within the last few years. The P450 enzymes add a level of fine-tuned modulation to the endocannabinoid system that actually attenuates or enhances the capacity of AEA and 2-AG to act as signaling molecules. COX and LOX products 5,6 EET-EAS: epoxy eico satrienoic acid ethanolamides
- anandamide is synthesized by neurons in the brain in an activity-dependent mechanism. Studies reporting a personality difference between individuals with non-functional CYP2D6 protein and those expressing the functional form of the protein suggest that CYP2D6 may play an important role in the metabolism of psychoactive endogenous substrates
- What is very interesting is that the p450d6 enzyme does not degrade anadamide, but makes a 300x more selective and 1000 fold more strong binding molecule, an so called EPOXIDE called 5,6EET-EA
- The CB2 receptor is primarily expressed on immune cells, including microglia, which are the resident macrophage-like cells in the brain
- So in laymans terms, your brain has a mechanism build in that when exposed to inflammation or injury upregulates it’s p450D6 enzymes to produce these compunds that act like CBD on steroids, activating the immune cells that start cleaning up the mess that created the inflammation in the first place.
- 5,6-EET-EA, is significantly more stable than anandamide, which, as we learned before could have the effect of prolonged exposure to the receptor flipping to not decreased short term memory
- So now you have these glyphosate rich vaccines hitting our kids constantly, knocking the enzyme out of the brain, so you can imagine the consequences. Any toxin that you will have, may it be aluminum, mercury, copper, viruses, anything…will be just sitting there causing further damage, because the 5,6EET is not able to activate the microglia strong enough, if at all….
- So what are we going to do? Well, according to uncle sam’s friendly paper 6630507‘Cannabinoids have been found to have antioxidant properties, unrelated to NMDA receptor antagonism’
- In fact the microglial cells also have the TRVP receptor which can lead to microglial activation.
- It only makes sense about what we have been learning about THC and CB1 that if you find the right dose, the receptor will be saturated and will not lead to short term memory dysfunctions
- In case you don’t know who this is, Dr. JB, he was reversing Autism with some of his patients.
- Dr. Bradstreet was studying GcMAF Out of 2000 children,85% improve, of them 15% have their autism eradicated Once this paper came out, he died. His family had an independent investigation confirming he was murdered. Currently they are filming this story with Discovery ID on the east coast. In regards to Dr. Bradstreets team, they marketed Rerum after his death
- GCMAF is an immunologically important protein responsible for macrophage activation which requires activated vitamin D (aka vitD binding protein) from the liver
- He knew the liver wasn’t converting the vitamin D correctly
- And all it is is the vitD that your liver can’t make because of glyphosate toxicity. Well…quite honestly, we hardly see it it anywhere as a true breakthrough for autism. My friend Dwight used it for his son, and it hasn’t done really much. I don’t want to say it doesn’t work for others, I don’t know, but when I met with Jeff’s family after his death I was granted access to his research folders and low and behold I found him to be very interested in cannabis research.
- When I repeatedly met with his brother and wife they claimed that he only received those 85% with cannabis.
- Liver regeneration after partial hepatectomy is a very complex and well-orchestrated phenomenon requiring complex signaling mechanisms that are poorly understood. We do know however, that it can regenerate. We have new evidence that demonstrates heavy endocannabinoid upregulation in the inflamed gastrointestinal and liver tissues. We believe the answer is juicing raw cannabis leaves, which according to research has 50 x the medicinal potency when compared to smoking or vaping. We are currently researching raw, cold pressed cannabis juice. In that sense I believe Autism ultimately is a primary disease of the liver.
- Because this
- Would turn into this. Without anyone profiting, but those who really need to profit. Our children. And our grandchildren.