Most Leading Biotech Companies.pdf

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I N D I A
MOST LEADING
COMPANIES
VOL 07 | ISSUE 08 | 2023
Tech-Upgrades
Implementing AI in
the Enhancement of
Biotechnology
Industry Insider
Emerging Trends
in the Healthcare
Sector

MOST LEADING
COMPANIES
#CIOLOOKINDIA

Pioneers in
life science technologies

he pharmaceutical and biotech industries have seen
Ta significant increase in innovation and
technological advancements in recent years.
Precision medicine is an innovative approach to patient care
that involves tailoring treatments to individual patients
based on their genetic makeup, environment and lifestyle.
This approach allows for more targeted and personalized
treatments, which can lead to better outcomes and reduced
side effects.
AI and ML are being used to revolutionize drug discovery
and development by analyzing large datasets and
identifying potential drug candidates faster and more
efficiently than traditional methods. Moreover, Gene
therapy is an emerging field that involves using genetically
engineered viruses to deliver therapeutic genes to patients.
This approach has the potential to cure genetic diseases by
replacing or repairing faulty genes. Digital health solutions,
such as mobile apps and wearables, are being developed to
help patients manage their health conditions and provide
healthcare providers with real-time data to make informed
decisions.
3D printing technology is being used to create personalized
medical devices and implants, such as prosthetics and
dental implants, which can improve patient outcomes and
reduce costs.
Blockchain technology is being explored as a way to
improve the efficiency and security of drug supply chains,
clinical trials and medical records.
Overall, these innovations are driving significant advances
in the pharmaceutical and biotech industries, with the
potential to improve patient outcomes, increase efficiency
and reduce costs. Some of the innovative companies in the
niche are utilizing these trends and benchmarking
excellence with core innovation. Spotlighting these
gemstones of the pharma and biotech niche, CIOLook India
showcases “Most Leading Biotech Companies.”
Flip through the pages and indulge in the odyssey of
prolonged brilliance. Have a delightful read!
Abhishek Joshi
Deputy Editor
AbhishekJoshi
Leading the
Way in Biotech Innovation

08 Akshar biotech Pvt. Ltd.
Reshaping the world of green Energy
14
26
P
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o
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s
A
r
t
i
c
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e
s
18
22rise N’ Shine biotech pvt. ltd.
Industry Insider
Emerging Trends in the Healthcare Sector
Tech-Upgrades
Implementing AI in the Enhancement of Biotechnology
diverse genomics
Implementing the Next Generation Sequencing
Leveraging scientific temperament and environmental
consciousness with the promise of delivering
qualitatively superior Tissue Culture planting material
and other planting products

Akshar Biotech is an
organiza on established
with the principal aim of
tapping and developing the
renewable energy sources
market and making the
world a be er place to live in
with less pollu on.
BioResource is a Marke ng
and Distribu on Company in
the field of Life Sciences,
Healthcare, Diagnos cs,
Molecular Diagnos cs,
Pharmaceu cals, BioPharma,
Agriculture, Veterinary
Science, Food industries, and
chemical science.
Diverse Genomics,
headquartered in Kolkata,
India, is a first of its kind
cu ng-edge technology-
based premier molecular
diagnos cs company and
research organiza on
providing services in Kolkata
and Eastern India.
Kan biosys is a specialized
agri-biotech company
working in the field of plant
nutri on and pest
management, with a vision
to be pan India and then
global, to bring full plant
poten al to life by microbial
inputs and precision
agriculture.
Akshar Biotech
Pvt. Ltd.
Mr. Bharat G Savaliya,
Founder
Rise n’ Shine Biotech is a
pioneer in Plant
Biotechnology, with ac vi es
that cover a wide range of
interlinked ver cals like
Biotechnology, Floriculture,
Hor culture and Exo c plant
nursery.
Descrip on
Sheet
BioResource Biotech
Pvt. Ltd.
Jagannath Sonawane,
Chairman
Diverse Genomics
Pvt. Ltd.
Saurav Jaiswal,
CEO and Co-founder
Kan Biosys
Pvt. Ltd.
Sandeepa Kanitkar,
CMD and Founder
Rise n' Shine Biotech
Pvt. Ltd.
Dr Bhagyashree Pa l,
Chairperson and Managing Director
MOST LEADING
COMPANIES

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Credit
Page
JULY
2023
Editor-in-Chief - Pooja M. Bansal
Deputy Editor - Abhishek Joshi
Art & Design Head - Sandeep Tikode
Co-designer - Deepanjali Jena
A.Vice President - Swapnali Vasaikar
Sr. Manager - Tejaswini Whaval
Team Lead - Suraj Gadekar
BDE - Geetha Reddy
Technical Head - Prachi Mokashi
Technical Consultant - Prashanth Hiremath
Circulation Manager - Tanaji Fartade
Research Analyst - Nikita Khadalkar
SEO Executive - Ravindra Kadam
I N D I A

Reshaping the World of Green Energy
The energy crisis is not new to our generation.
From electricity to fuelling vehicles with either
petrol, diesel or gas, non-renewable sources of
energy will extinct one day. The reason why must we
strive for newer ways of energy generation gives solutions
to the problem. Gas, whether it is used for kitchen and
household purposes or it is used at bigger industrial
levels, is also facing a shortage. To tackle this situation,
the Indian Government has taken numerous initiatives
with various private industries for the production of
cattle-dung biogas over the years.
Diﬀerent in this race, Akshar Biotech Pvt. Ltd. is taking
a unique approach to biogas generation with the help of
food waste. Under the guidance of Mr. Bharat G
Savaliya, the company has been on the journey of
protecting Mother Earth with his brilliant ideas of
producing biogas and implementing energy plants.
Mr. Bharat G Savaliya
Founder
Mr. Bharat has been
just the right person to
guide by providing
operational and
programmatic support
the organization.
“ “
PROFILE
08

Seeing the Big Picture, Nailing the Details
Mr. Bharat G Savaliya is the founder of Akshar Biotech
and serves as the President of the same. He brings his
industry expertise arising from years of experience in the
international design, construction and bioenergy sector.
Bharat has always had a knack for seeing what others don’t
yet see. With his belief in the word that ‘we have to
preserve the Good Earth for our future generations,’ he
always looked for ways to protect the earth.
In 2011, when very few were fretting about climate change
due to greenhouse gas emissions, he had the foresight to
start a study of biogas projects through all his globetrotting.
The project was with a $5,000 investment that eventually
grew into India-based Akshar Biotech, one of Asia’s most
promising Bioenergy companies.
Bharat Savaliya holds a degree in higher secondary and
has over nine years of Bioengineering experience in the
construction of various industrial and commercial
projects. He has held various executive business
positions in various national companies around the
world. He also won awards for his best engineering
practices from the International Consultants group. He
serves as a member of the boards of various
environmental and social organizations. Moreover,
Sadhanaben Savaliya is one of the partners of the
company and serves as the Managing Director of the
same.
Proving the Value of Good Service
Mr. Bharat has been just the right person to guide by
providing operational and programmatic support to the
organization. He has earned the tag of “A very bright star in
the finance department” through an era of wrenching
change. He has over 20 years of experience in the finance
and accounting industry. He worked on various assignments
including project financing activities, budgeting, cash flow
forecasting, and setting up and implementing procedures
and systems to maintain best accounting and finance
practices. He has also worked within the textile and
automotive industries too. Being the President of Finance at
Akshar Biotech, he is responsible for the accounting and
project financing activities.
Creating a Storehouse of Value
Mr. Yash Savaliya serves as Executive Manager at the
company. A man willing to do whatever it takes to
succeed in the right way, Yash is clearly motivated by a
need for achievement. As Executive Manager, he plays a
significant role in long-term planning with an initiative
geared towards operational excellence. With his proven
leadership and team-building skills, he is suited for the
implementation of business strategies as per the vision of
the management team.
This brilliant Theologist has always had the quest to follow
the word and work towards the betterment of mankind. This
has developed in him an excellent ability to communicate
and coordinate with consultants, contractors and clients
alike, making him the right choice for project
implementation.
Bioenergy: The Saviour
Talking about Bioenergy as the only solution to
environmental problems, Bharat Savaliya emphasizes the
importance of bioenergy in farming. He urges both retail
and institutional investors to load up on bioenergy farming
businesses. “Bioenergy can be the only solution to the
depleting energy sources,” says Bharat Savaliya. He has
never been afraid to try on different hats and with this, he
has vast experience in various fields like Engineering,
Project Management and Health Sector Administration. “It
is time to give back time and effort to the world and nature
itself,” adds Bharat Savaliya.
‘Do not Waste the Food Waste’
Green energy is the future of a country like India where
various sources are available to produce biogas energy.
Cow-based biogas manufacturing has become old as
newer techniques have emerged. Also, this method could
not give the expected results and according to Mr. Bharat,
one should try different tactics to solve the problem, just
like biogas production through a wide range of food
waste. This food waste may include agricultural residue,
by-products of horticulture, fruit & vegetables, energy
crops such as maize, organic municipal waste of
vegetables, waste of gardens and parks, sewage sludge,
and more. The energy generated using food waste can be
given to grids of electricity and thereby to the nearest
areas as well as residential properties.
Novel Biogas Plants
In Mr. Bharat’s opinion, the future of green energy is in the
hands of companies producing energy with a novel and
unique approach, to food waste energy production. Akshar
Biotech is highly efficient in creating customized Biogas
Plants. They include Waste to Energy Biogas Plants,
Renewable Energy Biogas Plants, Organic Waste Energy
Biogas Plants, and Waste Food Biogas Plants.
Biotech Companies | July 2023
09

Moreover, based on the availability of substrates specific to
the location and as per the individual client requirement, the
company makes available customized solutions to its
clients. All the equipment used in the making of the Biogas
Plant is precision engineered to meet the specific
requirements of the customers. Additionally, the team
provides outstanding technical and maintenance support to
the customers.
Expanding the Energy
Akshar Biotech has not only established its business of
producing green energy in parts of Surat but also
expanded it to the corners of Gujrat. The company has
the following projects:
• Atmiya Vidya Mandir: Situated in Kolibharthana,
Kamrej Surat, this plant has the capacity of
producing energy from 500 kg of food and
vegetable waste. This biogas is sent directly to the
kitchen for use.
• Banshi Gir Gaushala: Situated in Shantipura, SP
Ring Road, Ahmedabad, this plant has the capacity
of producing biogas from 2000 kg cow dung and
this Biogas is also directly sent to the kitchen and
boiler.
• Tejal Gaushala: Situated in Dungri, Mahuva
Bardoli, Surat, this plant can produce biogas from
5000 kg cow dung and this Biogas can be used to
direct boiler and kitchen.
• Agriculture Produce Market Committee: In the
market of Dumbhal Pune-Kumbharia Road, Surat,
this plant has a 5000 cubic meter row biogas
development plant purification plant. That is, the
plant uses 50,000 kg of vegetables and food waste
to produce biogas. Moreover, it has a capacity of
2200 kg CBG which can be directly supplied to the
Gujarat Gas Pipeline network daily.
• Agriculture Produce Market Committee: The
company has a plant in Jamalpur, near Callico mill
and in Shree Chimanbhai Jivabhai Patel market yard,
Vasana Ahmedabad. These plants produce 3000
cubic meters of row biogas plant from 30,000 kg of
vegetable and food waste and cow dung. This gas
purification 1200 kg CBG gas plant is used for
industrial purposes.
• Victory Green Energys Pvt. Ltd.: Situated in Vill,
Dhamdod, mangrol Near Kosamba, Surat, this plant
has 7500 cubic meters of row biogas product. It uses
75,000 kg of cow dung, Napier Grass, vegetable
waste, food waste, and sugar factory press mud to
produce biogas. It also has a 3200 kg CBG
purification plant development and this is directly
sent to Bharat Petroleum corporation ltd.
• Kakadiya Green Energy Pvt. Ltd.: (OP-COMING
PROJECT) Situated in Vill, Ranparda (khara)
Palitana Bhavnagar, this plant has 6000 cubic meters
of row biogas product. It uses 60,000 kg of cow
dung, Napier Grass vegetable waste, food waste, and
sugar factory press mud to produce biogas. It also
has a 3000 kg CBG purification plant development
and this is directly sent to Indian oil corporations.
• Solid and Liquid Fertilizers: Farmers use this for
benefits and chemical free farming.
11

Almost everybody is
enthusiastic about the
promise of biotechnologyto
cure disease and to
relieve suffering.

MOST LEADING
COMPANIES
I N D I A

Emerging
Trends
in the
Healcare
Sector
Article
14

he healthcare sector is undergoing a
Ttransformational journey driven by the
convergence of biotechnology and technological
innovations. This synergy has given rise to
groundbreaking solutions that are redefining diagnostics,
treatments, and patient care.
In this article, we delve into the emerging trends within
the healthcare sector that are closely tied to
biotechnology, showcasing how these advancements are
revolutionizing healthcare delivery and improving
outcomes for patients worldwide.
The Fusion of Biotechnology and Healthcare
Biotechnology, the application of biological knowledge
and techniques to develop products and processes, has
found a natural ally in the healthcare sector. The
integration of biotechnology with healthcare technologies,
such as data analytics, artificial intelligence, and precision
medicine, has led to a new era of personalized and more
effective treatments.
Emerging Trends in the Healthcare Sector
Precision Medicine and Personalized Treatments: One
of the most significant trends is the move towards
precision medicine. By analyzing an individual's genetic
makeup, lifestyle, and environmental factors, healthcare
practitioners can tailor treatments to the specific needs of
each patient. This approach maximizes treatment efficacy
while minimizing adverse effects. For instance, genetic
testing can identify mutations that make certain cancer
treatments more effective, ensuring that patients receive
treatments most suited to their unique genetic profiles.
Also, Foundation Medicine utilizes genomic profiling to
identify specific genetic mutations in cancer patients,
enabling oncologists to prescribe targeted therapies that
have a higher chance of success.
Industry
Insider
15

Gene and Cell Therapies: Advances in biotechnology
have paved the way for gene and cell therapies, offering
potential cures for previously untreatable genetic disorders.
Gene editing techniques like CRISPR-Cas9 allow scientists
to modify defective genes, potentially eliminating the root
causes of diseases. Cell therapies, such as CAR-T cell
therapy, harness the power of the patient's own immune
cells to target and destroy cancer cells. These therapies hold
immense promise for transforming the landscape of rare
diseases and oncology.
One example is the treatment of sickle cell anemia using
CRISPR to correct the genetic mutation responsible for the
disease. Additionally, Novartis's CAR-T cell therapy
reprograms a patient's immune cells to target and destroy
cancer cells, resulting in remarkable responses in previously
untreatable cases of leukemia.
Bioprinting and Organ Regeneration: Biotechnology is
making strides in the field of regenerative medicine.
Bioprinting, the process of creating functional living tissues
using 3D printing technology, holds potential for generating
replacement organs and tissues. This could alleviate the
global shortage of organ donors and revolutionize organ
transplantation.
Organovo, for instance, is working on bioprinting
functional human tissues, potentially addressing the
shortage of donor organs for transplantation. This
technology has the potential to transform the way we
approach organ replacement therapies.
Digital Health and Wearable Devices: The integration of
biotechnology and digital health technologies has led to the
development of wearable devices that monitor vital signs,
track fitness levels, and even diagnose diseases. Continuous
monitoring of health parameters allows for early detection
of potential health issues, empowering individuals to take
proactive steps towards better health.
The Apple Watch, for instance, includes features for
tracking heart rate, detecting irregular rhythms, and even
performing an electrocardiogram. These devices empower
individuals to monitor their health in real time and provide
valuable data to healthcare professionals.
Drug Discovery and Development Acceleration: The
pharmaceutical industry is benefiting from biotechnology's
ability to expedite drug discovery and development. AI-
driven algorithms analyze vast datasets to predict drug
interactions, identify potential candidates, and optimize
molecular structures. This streamlines the drug
development process, reducing costs and time-to-market for
new treatments.
Benefits and Transformative Impact
Patient-centric Approach: Emerging trends in
biotechnology-enhanced healthcare prioritize patients'
unique needs, leading to more accurate diagnoses and
effective treatments.
Disease Prevention and Early Detection: Advanced
diagnostics and personalized monitoring enable the
identification of diseases at earlier stages, increasing the
potential for successful intervention.
Improved Outcomes: Precision medicine and therapies
designed for specific genetic profiles enhance treatment
outcomes, leading to higher success rates and improved
patient quality of life.
Cost Efficiency: Biotech-driven innovations streamline
drug development and treatment approaches, potentially
reducing healthcare costs in the long run.
Global Health Impact: Emerging trends have the potential
to address global health challenges, offering solutions for
diseases that were once considered incurable.
The Future of Biotechnology-driven Healthcare
The future of the healthcare sector, enriched by the
integration of biotechnology, holds immense promise. As
research advances and technology evolves, personalized
treatments, gene therapies, and regenerative medicine will
likely become increasingly sophisticated and widely
accessible. The healthcare landscape is set to witness a
paradigm shift, as biotechnology's role in shaping the
industry's trajectory becomes more pronounced.
The convergence of biotechnology and healthcare is a
transformative journey that is reshaping how diseases are
diagnosed, treated, and managed. Emerging trends in this
space are pushing the boundaries of what is possible,
offering hope for patients and healthcare practitioners alike.
By fostering collaboration between researchers, clinicians,
policymakers, and industry stakeholders, we can harness
the power of biotechnology to propel healthcare into a
future where precision, innovation, and improved patient
outcomes converge.
Article
16

I N D I A
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DIVERSE
G e n o m i c s
Implementing the Next Generation Sequencing
Aiming to improve global health by developing deep
insights into diseases at the genetic and molecular
levels, Diverse Genomics Pvt. Ltd. is committed
to making genetic screening and testing accessible for all
patients.
The organization was incepted and Co-founded by Saurav
Jaiswal, with his passion for gathering knowledge from
different arenas of life, especially in science and
technology.
We caught up with Saurav and discussed how Diverse
Genomics aspires to transform medical genomics and
personalized therapeutics space.
Below are the highlights of the interview:
Kindly tell us the source of inspiration. What led you to
venture into the Biotech Industry?
My motivation for entering the biotech industry stems from
a personal tragedy I experienced. At the young age of 18, I
lost my mother to a brain tumor and cancer. This loss
inspired me to channel my energy and resources towards
improving cancer-related early detection, leveraging
cutting-edge biotech genomics sequencing technology. I am
driven by a passion to help others avoid the same fate as my
mother, and to make a meaningful impact in the fight
against cancer.
Brief us about yourself and shed some light on your role
and responsibility at the company.
Also, being the CEO, I manage operations across the
complete business cycle, starting from HR, R&D, Clinical
Oncology, Genomics, Business Development & Sales, and
other corporate functions. Subsequently, he helps raise
capital and earn revenue for the company's future wealth
creation.
Brief us about the rising need for Biotech software in
the healthcare sector. How will it impact how patients
receive treatment and the clinical decisions taken by
care providers?
The healthcare sector is increasingly relying on biotech
software to improve patient care and treatment outcomes.
The rise of big data, cloud computing, and artificial
intelligence has created new opportunities for biotech
software to be applied in various aspects of healthcare,
including:
Precision Medicine: Biotech software can be used to
analyze large amounts of genomic, proteomic, and clinical
data to identify individualized treatment plans for patients.
This can help improve the accuracy of diagnoses and
predictions of disease progression, leading to better patient
outcomes.
Clinical Decision Making: Biotech software can provide
care providers with real-time access to patient data and
analytics, helping to support more informed clinical
decisions. This can improve the speed and accuracy of
diagnoses, reduce medical errors, and lead to better patient
outcomes.
Drug Discovery: Biotech software can help speed up the
drug discovery process by enabling researchers to quickly
analyze large amounts of data on potential drug targets,
accelerating the development of new treatments.
Telemedicine: Biotech software is playing an increasingly
important role in supporting remote patient monitoring and
telemedicine, helping to improve access to care for patients
in rural or remote areas.
In summary, the use of biotech software in healthcare is
expected to have a major impact on the way patients receive
treatment and the clinical decisions made by care providers.
PROFILE
18

The healthcare
sector is
increasingly turning
to biotechnology
software to improve
patient care and
streamline clinical
decision-making.
Biotech software
can be used for
tasks such as data
analysis, drug
discovery and
precision medicine.
Saurav Jaiswal,
CEO and Co-founder
Diverse Genomics Pvt. Ltd.
19

By improving the accuracy and speed of diagnoses,
reducing medical errors, and supporting personalized
treatment plans, biotech software is poised to play a critical
role in advancing the quality of patient care in the years to
come.
What unique biotech solutions does your company offer
compared to other companies that have already come up
with similar software to resolve current healthcare
issues? What factor sets it apart from the rest in the
market?
We are focused on the non-invasive way of DNA extraction
–which is more accessible and hassle-free for patients. We
are trying to eliminate cold chain logistics for sample
shipment with an advanced IVD-approved sample
collection kit, which requires minimum shipment effort.
We have developed our proprietary tests KARK-Early
detection for multiple cancer solutions, supported by our
unique bioinformatics pipelines, proprietary databases, and
collaborators.
Our cloud computing power has increased with the help of
our partnership with Google for Start-ups (GCP); our
bioinformatics and data processing cycle time will be
reduced from weeks to days and will increase productivity.
What specific R&D operations are your company
leading at present? Why do you find them essential in
developing BioTech solutions?
Whole exome sequencing (WES) is a powerful genetic
technique that allows researchers to analyze all the protein-
coding regions of the genome (the exome) to identify
genetic variants that may be associated with a particular
disease or trait. Companies that are leading in the
development and implementation of WES technology for
research and diagnostic applications are essential in
developing biotech solutions for several reasons:
Identifying Genetic Variants: WES allows for identifying
genetic variations that may be associated with a particular
disease or trait, which is a critical step in understanding the
underlying biology of an illness and developing new
diagnostic and therapeutic options.
Advancement of Personalized Medicine: WES can
identify genetic variations that may influence an
individual's response to a particular treatment, which can
help optimize treatment decisions and improve patient
outcomes.
Improved Diagnostic Accuracy: WES can be used to
identify genetic variations that may be associated with a
particular disease, which can help to improve the accuracy
of diagnostic testing and reduce the number of false
positive and false negative results.
Drug Development: WES can be used to identify genetic
variations that may influence an individual's response to a
particular drug, which can help to optimize drug
development and improve the chances of success in clinical
trials.
Scalability: Leading companies in WES technology have
the resources and infrastructure to scale up the production
of these tests, making them more accessible to patients.
Therefore, companies leading in developing and
implementing WES technology play a vital role in
advancing our understanding of the genetic basis of
diseases and developing new diagnostic and therapeutic
options. They are essential in helping to translate genetic
discoveries into clinical practice and improve patient
outcomes.
In what way do you consider technological advances a
pathway in conducting your operations?
In recent years, there has been a significant advancement in
the use of AI and computing in DNA sequencing. Some
examples include:
• Improved algorithms for DNA assembly, which use
machine learning techniques to put together the
sequences of DNA more accurately and efficiently.
• Developing deep learning models for variant calling
allows for identifying genetic mutations with greater
accuracy.
• Use cloud computing and high-performance computing
to process large amounts of DNA sequencing data,
allowing faster and more efficient analysis.
• The development of AI-based tools for interpreting
genomic data can help identify genetic markers for
diseases and aid in discovering new therapies.
• Advancements in CRISPR technology allow precise
DNA sequence modifications with the help of AI-based
software.
Overall, the combination of AI, computing, and DNA
sequencing is revolutionizing the field of genomics and has
an enormous potential to improve the diagnosis and
treatment of diseases, in addition to making gene editing
more precise and efficient.
20

What endeavours is the company pursuing to improve
its service measures for the clients?
POCT "Point of Care Testing," which refers to medical
tests that are performed at or near the site of patient care,
rather than in a laboratory.
Streamlining Test Processes: Improving the speed,
accuracy, and reliability of POCT tests can help provide
quicker results and a better experience for clients.
Providing Patient Education and Support: Providing
patients with information and support throughout the testing
process can help alleviate any concerns or worries they may
have and improve their overall experience.
Non-invasive way of collecting samples–Oral swab and
Blood.
Liquid Biopsy is a non-invasive method for detecting and
analyzing cancer cells using biological fluids such as blood.
Advancements in AI and computing have played a
significant role in developing liquid biopsy technology.
Overall, liquid biopsy technology has the potential to
revolutionize cancer detection and treatment, allowing for
earlier and more accurate diagnosis, as well as providing
essential information for treatment decisions.
What advice would you like to give to budding
entrepreneurs and enthusiasts who desire to venture
into the Biotech Industry?
Biotechnology requires significant capital, long gestation
periods, and enormous patience. Biopreneurship can be
challenging, as it often involves significant financial and
technical risks. However, it can also be gratifying, as
successful ecopreneurs can substantially impact society and
improve human health.
How do you envision scaling the company's services and
operations in 2023 and beyond?
Scaling the company's services and operations in 2023 and
beyond will likely involve several different strategies,
depending on the specific goals and circumstances of the
company. However, some possible ways to scale the
company's services and operations include the following:
Expanding the company's customer base: This can be
achieved by increasing marketing and sales efforts,
developing new partnerships and collaborations, and
entering new markets.
Developing new products and services: This can include
creating new liquid biopsy tests, expanding the range of
cancers that can be detected, and developing new
technologies to improve the accuracy and reliability of the
tests.
Investing in automation and digitalization: This can
include implementing automation technologies in the lab
and using digital platforms to improve the efficiency and
scalability of the company's operations.
Building a strong team can include:
• Recruiting and retaining top talent,
• Investing in employee training and development, and
• Creating a positive and supportive work environment.
Investing in research and development: This can include
funding research projects to develop new products and
services and exploring new technologies to improve the
company's services and operations.
Leveraging new technologies: Biotechnology is advancing
rapidly; there are new technologies such as CRISPR, AI,
and machine learning that can be integrated into the
company's services to improve the diagnosis and treatment
of cancer.
Focusing on cost reduction: The company can focus on
reducing costs through automation, process optimization,
and implementing technology to improve efficiency, which
can help to lower the cost of liquid biopsy and make it more
accessible to more patients.
Building strategic partnerships: Building partnerships
with other biotech companies, pharmaceutical companies,
and academic institutions can help the company to access
new technologies, funding, and expertise, which can
support the company's growth and expansion.
21

Rise N' Shine
Biotech Pvt. Ltd.
Leveraging scientiﬁc temperament and environmental consciousness with
the promise of delivering qualitatively superior Tissue Culture planting
material and other planting products
Rise n’ Shine is pleased to report that it has now experienced
amazing growth in terms of infrastructure expansion and
production capacity, enabling it to offer unwavering support to
all of its clients in an even greater manner than before.
profile
22

Her optimistic outlook on life, diligence, sheer willpower,
perseverance, and dedication made all of this possible. She
has a strong commitment to her career. She came from a
simple farming background and has set an adventure with
the intention to serving farmers of our country with good
quality planting material.
She has always encouraged, supported, and empowered
women. Rural women are encouraged to work and
contribute to be financially independent as well as
financially support their families. They also learn how to
successfully balance their personal and professional life.
Empowering women means equipping them with the tools
they need to have power and control over their own lives in
terms of self-strength to efficiently build women. Dr.
Bhagyashree Patil says, "A woman has to be strong in
respect of her social acceptance, education, economic
status, and most importantly, psychological strength." She
also believes that women's empowerment ranges from self-
strength to building women's efficiency. She has always had
a comprehensive approach to the upliftment of the farming
community, and hence her success story is known across
the globe.
Making a Difference
Theur is the hub of “Rise n’ Shine Biotech Pvt. Ltd.,”
which is home of one of the “Ashtavinayak Lord
“Chintamani Ganesha” – the local ecosystem was solely
dependent on the Cooperative Sugar Factory. After the
closure since 2011, the local population has suffered
unemployment which has impoverished the local
population and adversely affected households. The
determination and hard work of Dr.Bhagyashree Patil
took a lead to step the growth from 4000 sqft lab in 2004
to 280,000 sqft lab today. The rapid success of “Rise n’
Shine Biotech Pvt. Ltd.” has given employment
opportunities to a large number of women from about
10-12 nearby villages. Total 85% of the employees are
women in her company.
Regular Medical checkup ,Yoga classes during working
hours , Books distributions for the students of nearby
villages’ school, Groceries distribution for labour and
needy are the part of CSR activities on regular basis
from her initiative.
Rise n’ Shine Biotech Pvt. Ltd. has developed a solid
network of cooperative ties with reputable international
businesses.
Rise n' Shine Biotech Pvt. Ltd. is a pioneer in plant
biotechnology in India. It engages in an assortment
of interconnected vertical operations, including
biotechnology, floriculture, horticulture, and exotic plant
nurseries. The business is a pioneer in the field of plant
biotechnology based in Pune.
The company is India's largest plant tissue culture company,
and it is certified by the Department of Biotechnology,
Government of India, to ISO 9001:2015, DBT, and NCS-
TCP. It is headquartered in Pune, Maharashtra, India. The
first floriculture company in India to breed the best Gerbera
varietals!
Rise n’ Shine has an 8,000-square-foot, state-of-the-art
high-tech research and development lab that have been
approved by the Department of Scientific and Industrial
Research (DSIR). This facility also contains a special
molecular biology lab for virus indexing.
The facility's is 2,80,000 Sq.ft laboratory & 1,80,000 square
meters of highly regulated greenhouse space produces
100% virus-free plants. The Exotic Nursery within the site,
which has a location in Kunjirwadi, Pune comprises 30
acres of poly houses and contains exotic and perennial
plants. Customers can also visit the Rise n’ Botanical
Boutique at Koregaon Park, Pune, which provides a well-
designed exotic store with a unique, unusual, and exquisite
collection of plants.
Rise n' Shine Biotech is a one-stop for all tissue culture
plant manufacturing and distribution. "Here we take the
opportunity to thank all our precious clients, national and
international business associates, and horticultural directors,
and are grateful to all for the constant support and direction.
The RNSB team takes pride in providing quality planting
material to all of its growers and farmers! Technical training
and guidance’s for the supplied planting material through
their expert Technical Managers who are expert in their
domain is a continual process.
About Dr. Bhagyashree Patil
Dr. Bhagyashree Patil, the Chairperson and Managing
Director of the Rise n' Shine Group of Companies in Pune
and the Pro-Chancellor of the Dr. D. Y. Patil Vidyapeeth ,
Pune, is the inspiring leader and driving force behind the
success of Rise n’ Shine.
She is a multifaceted woman-successful entrepreneur,
educationist philanthropist and a Super Motivational
Bharatnatyam dancer learned at a very short span of time.
23

Ethiopia, etc., is training. The most recent reports concern
Ethiopia's excellent harvest, where Prime Minister,
Respected Mr. Abiy Ahmed Ali, visited a farmer's plot and
observed the excellent harvest. The entire banana plants in
Ethiopia were provided by Rise n’ Shine Biotech.
The company’s Chairperson & Managing Director, Dr.
Bhagyashree Patil, thanked the farmer family & Hon’ble
Prime Minister, Respected Mr. Abiy Ahmed Ali, Ethiopia,
for visiting the Ethiopian farmers and appreciating the
bumper production received from Rise n’ Shine Biotech
Pvt. Ltd., Quality Banana Plants! She states, “We are
grateful to the farmers from the Ethiopian family for
trusting Rise n’Shine Banana Plants! And assure Quality
planting material always along with the Technical
Support.”
Likewise, complete technical support and assistance are
given to Rise n’ Shine’s national farmers who are growing
floriculture products. The company is proud to announce
that all its floriculture growers/farmers are successfully
earning a profit from their investment and serving the
nation in their way. The company has developed Bengaluru,
Hyderabad, and many other cities, where it has stories from
its successful & hardworking farmers & growers.
Awards for Exceptional Work
Dr. Bhagyashree Patil, many a time known as a lady with a
mission has been conferred with many awards. She was
conferred with the prestigious award "Laxmibai
Making Global Alliances
India and the Netherlands are celebrating 75 years of
diplomatic relations. Today, India and the Netherlands
enjoy strong political, economic, and commercial relations.
Rise n’ Shine Biotech Pvt. Ltd., India, is always pleased to
be associated with valuable Dutch business partners in the
Netherlands.
A friend in need is a friend indeed. Presently, many
countries are facing rising energy prices, supply chain
disruptions, a decreasing labor supply, etc., which includes
the Dutch business sector also. Sector experts expect
significant consolidation, with a 30 to 40 percent reduction
in businesses. Dr. Patil believes that together, companies
will overcome all challenges. She states, "We extend our
hand to the entire Netherland business association to do
their tissue culture production very much in India and at
Rise n’Shine Biotech Pvt. Ltd., www.risenshine.in ”
Dr. Bhagyashree Patil also sees challenges as the perfect
opportunity to stretch one's limits to embrace new, positive
emotions in the face of adversity while guiding those
around oneself.
Empowering Farmers
Rise n’ Shine has always believed in offering its community
of farmers and producers solid technical training. The
strongest point at which it has communicated with its
domestic and international farmers and growers, as well as
the company's commercial partners abroad in countries like
24

SmrutiPuraskar–2022,” from the auspicious hands of the
Hon'ble President of India Shri Ram Nath Kovindji, and
“Mahatma Gandhi Samman” at the House of Commons,
London, 2022.
Rise n’ Shine has also received the “Outstanding
Achievement Award for Farmers Welfare” (2021), “Leading
Plant Biotechnology Company for Banana Plants” at the
Fresh India show, New Delhi (2021), “Best Entrepreneur
Award 2021” by ICAR-NATIONAL RESEARCH
CENTRE FOR BANANA, IRUCHIRAPALLI (2021),
“International Excellence Awards for Corporate
Leadership” at Dubai, (2019), “Outstanding Women
Leadership Award for Business Excellence” at Bangkok
(2019),” “Indian Agribusiness excellence award for Women
Empowerment” (2017), “Krishi Kanya” (2017), “The
Government of Maharashtra Entrepreneurial Award”
(2018), “Fastest Growing Indian Company Award”
Bangkok, Thailand (2015), “Muktai Gaurav Puraskar”
(2008), “Top Management Consortium” (2008),
“RashtriyaNirman Ratan Award” (2009), etc.
Vision for Expansion
An expansion is a road map outlining the approach Rise n’
Shine will take to achieve well-established development in
every way. The NewYear 2023 offers a fresh perspective for
Rise n’ Shine.
Rise n’ Shine is pleased to report that it has now
experienced amazing growth in terms of infrastructure
expansion and production capacity, enabling it to offer
unwavering support to all of its clients in an even greater
manner than before.
Currently, Rise n’ Shine has a 2,80,000-square-foot state-of-
the-art, high-tech tissue culture laboratory with a production
capacity of more than 45 million plants annually. This
enables the company to serve its production alliance
partners nationally and internationally for the production of
crop varieties from different verticals-floriculture,
horticulture, and nursery crops like Gerbera, Carnation,
Orchid, Chrysanthemum, Gypsophila, Limonium,
Spathiphyllum, Bromeliad, Anthurium, Banana, Strawberry,
Pomegranate, Pineapple, Citrus Fruits, Thai Guava, and
several other nursery plants.
The market analysis method used by Rise n’ Shine is a
continuous process. The team solicits regular client
feedback to choose the products that would best serve the
needs of the market. The marketing team has the technical
expertise and creativity to develop original viewpoints and
investigate cutting-edge tactics. Additionally, they foresee
market developments, provide timely customer counsel, and
ensure client satisfaction and happiness.
25

Implementing AI
in the
Enhancement of
Biotechnology
he integration of artificial intelligence (AI) into the
Tfield of biotechnology has ushered in a new era of
possibilities. Biotechnology, the application of
biological systems and organisms to create or modify
products and processes, has experienced remarkable
advancements over the years. With the advent of AI, the
synergy between these two domains has paved the way for
unparalleled breakthroughs, transforming the landscape of
healthcare, agriculture, and environmental sustainability.
This article explores the role of AI in biotechnology, its
applications, benefits, challenges, and the promising future
it holds.
The Confluence of AI and Biotechnology
The convergence of AI and biotechnology marks a
revolutionary juncture in scientific progress. Artificial
intelligence is a branch of computer science that deals with
the creation of machines capable of intelligent behaviour.
Biotechnology, on the other hand, harnesses biological
systems for industrial, medical, and scientific applications.
The merging of these two disciplines has led to significant
strides in the understanding of complex biological
processes and the development of innovative solutions.
*Applications of AI in Biotechnology
Drug Discovery and Development: AI accelerates the
drug discovery process by analyzing massive datasets to
identify potential drug candidates. Machine learning
algorithms predict molecular interactions, analyze protein
structures, and simulate drug-target interactions, reducing
the time and cost required for drug development.
For instance, Atomwise employs AI to predict the binding
affinity of molecules to target proteins, drastically reducing
the time and resources required for identifying potential
drug candidates. By analyzing vast datasets, AI algorithms
can predict molecular interactions and assess drug safety
profiles, resulting in more efficient drug development
pipelines.
Precision Medicine: AI analyzes patient data, including
genetic information and medical history, to tailor treatment
plans for individuals. This approach increases treatment
efficacy, reduces adverse reactions, and improves
patient outcomes.
AI's prowess in analyzing complex patient
data is exemplified by IBM's Watson for
Oncology. By sifting through medical
records, research papers, and
clinical trials, this AI system
provides oncologists with
tailored treatment options
based on a patient's genetic
profile, medical history,
and available evidence.
This personalized
approach enhances
treatment efficacy and
patient outcomes.
Article
26

Tech-Upgrades
27

Genome Editing: AI algorithms aid in designing and
optimizing genome editing tools such as CRISPR-Cas9,
enabling precise modifications to DNA sequences. This has
vast implications in disease research and agriculture. The
revolutionary CRISPR-Cas9 technology has been further
optimized with AI assistance. AI algorithms predict the
outcomes of genetic modifications and guide the design of
CRISPR sequences for precision editing. This synergy has
expedited genetic research and opened avenues for potential
therapeutic interventions in genetic disorders.
Bioprocess Optimization: AI optimizes fermentation
processes, protein production, and other bioprocessing
tasks. This results in higher yields, improved product
quality, and reduced resource consumption.
Biomarker Discovery: AI identifies novel biomarkers
indicative of diseases, allowing for earlier diagnosis and
better monitoring of patient health. Google's DeepMind
demonstrated AI's potential in predicting protein folding, a
crucial step in understanding disease mechanisms and
designing targeted therapies. This breakthrough has far-
reaching implications for drug design and biomarker
identification.
Synthetic Biology: AI assists in designing and constructing
synthetic biological systems for various applications,
including biofuel production and environmental
remediation.
Agricultural Advancements: AI is transforming
agriculture through applications like Plantix. This app
employs image recognition and AI algorithms to diagnose
crop diseases and nutrient deficiencies by analyzing photos
of plants taken by farmers. Such technology aids in
identifying problems early, leading to improved crop yields
and reduced chemical usage.
*Benefits of AI in Biotechnology
Speed and Efficiency: AI algorithms process vast amounts
of data quickly, accelerating research and development
processes.
Personalization: AI enables tailored treatments and
interventions based on individual genetic profiles,
enhancing healthcare outcomes.
Data-driven Insights: AI uncovers hidden patterns in
complex biological data, leading to novel discoveries and
insights.
Resource Optimization: AI-driven bioprocessing reduces
resource consumption, making biotechnology more
sustainable.
Innovation Catalyst: AI inspires the creation of novel
technologies, revolutionizing the biotechnology landscape.
*Challenges and Considerations
Data Quality and Quantity: AI relies on extensive, high-
quality datasets. In biotechnology, obtaining sufficient and
accurate data can be challenging.
Ethical Concerns: The ethical implications of AI-
generated biological entities and the potential for
unintended consequences require careful consideration.
Interdisciplinary Collaboration: Effective
implementation of AI in biotechnology necessitates
collaboration between biologists, computer scientists, and
domain experts.
Regulatory Hurdles: The regulatory framework for AI-
augmented biotechnological products and processes is still
evolving.
The Road Ahead
The future of AI in biotechnology is promising. As AI
algorithms become more sophisticated, they will better
simulate complex biological processes and predict
outcomes. Researchers are working on developing AI
systems that can design completely new proteins,
revolutionizing drug development and biocatalysis. AI-
driven diagnostics and treatment plans will become
increasingly personalized, ushering in an era of precision
healthcare. Furthermore, AI's potential to enhance crop
yields and optimize agriculture will play a pivotal role in
addressing global food security challenges.
The integration of AI and biotechnology represents a
groundbreaking convergence that holds immense potential
for advancing human health, environmental sustainability,
and scientific knowledge. As the capabilities of AI continue
to evolve, its contributions to biotechnology will reshape
industries, improve patient care, and unlock previously
unimaginable solutions to some of humanity's most
pressing challenges. To fully realize these benefits, it is
crucial for researchers, policymakers, and stakeholders to
collaborate in addressing ethical, regulatory, and technical
considerations, ensuring a responsible and impactful
integration of AI in the enhancement of biotechnology.
Article
28

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