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Borgia-Lim

Education Technology

SCIENCELITERACY
ARTICLE12- forFebruary3,2012

Electrical Stimulation of Brain Boosts Birth of New Cells: Animal Study Suggests Deep
Brain Stimulation Improves Memory

ScienceDaily(Sep.20,2011)—
Stimulatingaspecificregionofthebrainleadstotheproductionofnewbraincellsthatenhancememory,accordi
ngtoananimalstudyintheSeptember21issueofTheJournalofNeuroscience.Thefindingsshowhowdeepbrain
stimulation(DBS)--aclinicalinterventionthatdeliverselectricalpulsestotargetedareasofthebrain—
mayworktoimprovecognition.

"DBShasbeenquiteeffectiveforthetreatmentofmovementdisorders,suchasParkinson'sdisease,andhasrece
ntlybeenexploredfortreatmentofarangeofneurologicandpsychiatricconditions,"saidPaulFrankland,PhD,of
TheHospitalforSickChildren(SickKids),seniorauthorofthestudy."These new findings have important
clinical implications as they inform potential treatments for humans with memory disorders."

Throughoutlife,newcellsareborninpartsofthehippocampus,thebrain'slearningandmemorycenter.Inthene
wstudy,Franklandandhiscolleaguesfoundthatonehourofelectricalstimulationtotheentorhinalcortex--
aregionthatdirectlycommunicateswiththehippocampus--inadultmiceledtoatwo-
foldincreaseinnewcellsinthehippocampus.Althoughtheburstofnewcellslastedforonlyaboutoneweek,thec
ellsproducedduringthistimewindowdevelopednormallyandmadeconnectionswithothernearbybraincells

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Scienceliteracy

1. SCIENCELITERACY ARTICLE12- forFebruary3,2012 Electrical Stimulation of Brain Boosts Birth of New Cells: Animal Study Suggests Deep Brain Stimulation Improves Memory ScienceDaily(Sep.20,2011)— Stimulatingaspecificregionofthebrainleadstotheproductionofnewbraincellsthatenhancememory,accordi ngtoananimalstudyintheSeptember21issueofTheJournalofNeuroscience.Thefindingsshowhowdeepbrain stimulation(DBS)--aclinicalinterventionthatdeliverselectricalpulsestotargetedareasofthebrain— mayworktoimprovecognition. "DBShasbeenquiteeffectiveforthetreatmentofmovementdisorders,suchasParkinson'sdisease,andhasrece ntlybeenexploredfortreatmentofarangeofneurologicandpsychiatricconditions,"saidPaulFrankland,PhD,of TheHospitalforSickChildren(SickKids),seniorauthorofthestudy."These new findings have important clinical implications as they inform potential treatments for humans with memory disorders." Throughoutlife,newcellsareborninpartsofthehippocampus,thebrain'slearningandmemorycenter.Inthene wstudy,Franklandandhiscolleaguesfoundthatonehourofelectricalstimulationtotheentorhinalcortex-- aregionthatdirectlycommunicateswiththehippocampus--inadultmiceledtoatwo- foldincreaseinnewcellsinthehippocampus.Althoughtheburstofnewcellslastedforonlyaboutoneweek,thec ellsproducedduringthistimewindowdevelopednormallyandmadeconnectionswithothernearbybraincells

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