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GKA deel 1 college 2

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Biology, Utrecht University
Biology, Utrecht University

Gentherapie: anti-sense en triplex

1 of 28
 
6 Genetische therapiën ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],GK 2009
The new genetic medicines Cohen/Hogan SciAm 271-6, 1994 GK 2009 ,[object Object],[object Object],[object Object]
Toetsvraag ,[object Object],[object Object],GK 2009
The new genetic medicines Cohen/Hogan SciAm 271-6, 1994 GK 2009 ,[object Object],[object Object],[object Object]
Structure of oligonucleotide Cohen/Hogan SciAm 271-6, 1994 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],GK 2009
Structuur morfolino GK 2009 Efficientie van remming 5’UTR Coding region Afstand van AUG
Ways to block expression Cohen/Hogan SciAm 271-6, 1994 GK 2009
Ways to block expression Cohen/Hogan SciAm 271-6, 1994 GK 2009
Ways to block expression Cohen/Hogan SciAm 271-6, 1994 GK 2009
Ways to block expression Cohen/Hogan SciAm 271-6, 1994 GK 2009
Ways to block expression Cohen/Hogan SciAm 271-6, 1994 GK 2009
Ways to block expression Cohen/Hogan SciAm 271-6, 1994 GK 2009
Genetic therapies 2006 ,[object Object],GK 2009
Genetic therapies 2006 ,[object Object],GK 2009 RNA interferentie: komt later
Structure of triplex molecule Cohen/Hogan SciAm 271-6, 1994 ,[object Object],[object Object],[object Object],[object Object],GK 2009
Anti-sense against c-myb Cohen/Hogan SciAm 271-6, 1994 ,[object Object],[object Object],GK 2009
Toetsvraag ,[object Object],[object Object],GK 2009
Overcoming the obstacles to gene therapy Friedman SciAm 276-6, 1997 ,[object Object],[object Object],GK 2009
Overcoming the obstacles to gene therapy Friedman SciAm 276-6, 1997 ,[object Object],[object Object],GK 2009 Toetsvraag: wat is het therapeutisch molecuul bij gentherapie? Geef details
Forms of SCID A. Fischer, Stockholm 2005 GK 2009 THYMUS CLP HSC Myeloid compartment Haemotopoietic stem cell Common lymphocyte precursor
Forms of SCID A. Fischer, Stockholm 2005 GK 2009 THYMUS CLP HSC Myeloid compartment Haemotopoietic stem cell Common lymphocyte precursor 1. Prevention of cell apoptosis DNA replication (purine metabolism) ADA
Overcoming the obstacles to gene therapy Friedman SciAm 276-6, 1997 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],GK 2009 Ashanti DeSilva with Dr. WF Anderson
Growing up in a sterile environment Friedman SciAm 276-6, 1997 ,[object Object],GK 2009
How to deliver genes Friedman SciAm 276-6, 1997 GK 2009
Viruses as gene vehicles Friedman SciAm 276-6, 1997 GK 2009
Viruses as gene vehicles Friedman SciAm 276-6, 1997 GK 2009
Adapting a virus Friedman SciAm 276-6, 1997 ,[object Object],GK 2009

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GKA deel 1 college 2

  • 1.  
  • 2.
  • 3.
  • 4.
  • 5.
  • 6.
  • 7. Structuur morfolino GK 2009 Efficientie van remming 5’UTR Coding region Afstand van AUG
  • 8. Ways to block expression Cohen/Hogan SciAm 271-6, 1994 GK 2009
  • 9. Ways to block expression Cohen/Hogan SciAm 271-6, 1994 GK 2009
  • 10. Ways to block expression Cohen/Hogan SciAm 271-6, 1994 GK 2009
  • 11. Ways to block expression Cohen/Hogan SciAm 271-6, 1994 GK 2009
  • 12. Ways to block expression Cohen/Hogan SciAm 271-6, 1994 GK 2009
  • 13. Ways to block expression Cohen/Hogan SciAm 271-6, 1994 GK 2009
  • 14.
  • 15.
  • 16.
  • 17.
  • 18.
  • 19.
  • 20.
  • 21. Forms of SCID A. Fischer, Stockholm 2005 GK 2009 THYMUS CLP HSC Myeloid compartment Haemotopoietic stem cell Common lymphocyte precursor
  • 22. Forms of SCID A. Fischer, Stockholm 2005 GK 2009 THYMUS CLP HSC Myeloid compartment Haemotopoietic stem cell Common lymphocyte precursor 1. Prevention of cell apoptosis DNA replication (purine metabolism) ADA
  • 23.
  • 24.
  • 25. How to deliver genes Friedman SciAm 276-6, 1997 GK 2009
  • 26. Viruses as gene vehicles Friedman SciAm 276-6, 1997 GK 2009
  • 27. Viruses as gene vehicles Friedman SciAm 276-6, 1997 GK 2009
  • 28.

Editor's Notes

  1. GKA 2009 a.a.m.thomas@uu.nl