SCIENTIFIC PUBLICATIONS AND ABSTRACTS ON NEUROTOXICITY
1. SCIENTIFIC PUBLICATIONS
S. Cukierman, W.C. Zinkand, R.J. French and B.K. Krueger. "Effects of Membrane Surface
Charge and Calcium on the Gating of Rat Brain Sodium Channels in Planar Bilayers" J.
GEN. PHYSIOL. Vol. 92, 431-447.
H. W. Dowden, R. Jahn, T. Catka, A. Jonsson, E. Michael, Y Miwa and W. C. Zinkand. "Industry
and Regulatory Performance in 2012: A Year in Review" CLIN. PHARMACOL THER. Vol.
94, 359-366.
A.C. Foster, W.C. Zinkand and R. Schwarcz: "Quinolinic Acid Phosphoribosyltransferase in Rat
Brain" J. NEUROCHEM. Vol. 44, 446-454.
J. Patel and W.C. Zinkand: "Role of Metabotropic Glutamate Receptors in Neuronal
Degeneration" in The Metabotropic Glutamate Receptors. P.J. Conn and J. Patel eds.
Humana Press.
J. Patel, W.C. Zinkand, C. Thompson, R. Keith and A. Salama: "Role of Glycine in the N-Methyl-
D-Aspartate-Mediated Neuronal Cytotoxicity" J. NEUROCHEM. Vol. 54, 749-755.
J. Patel, W.C. Zinkand, A.B. Klika, T.J. Mangano, R.A. Keith and A.I. Salama: "6, 7-Dinitro-
quinoxaline-2, 3-dione (DNQX) Blocks the Cytotoxicity of N-Methyl-D-Aspartate and
Kainate, but not Quisqualate in Cortical Cultures" J. NEUROCHEM. Vol. 55, 114-121.
L.M. Pullan, M.Britt, M.J. Chapdelaine, R.A. Keith, D. LaMonte, T.J. Mangano, J. Patel, R.J.
Powel, R.J. Stumpo, P.J. Warwick, W.C. Zinkand and A.I. Salama: "Stereoselectivity for
the R-enantiomer of HA-966 (1-hydroxy-3-aminopyrrolidone-2) at the Glycine Site of the
N-Methyl-D-Aspartate Receptor Complex" J. NEUROCHEM. Vol. 55, 1346-1351.
W.C. Zinkand, W.C. Moore, C. Thompson, A. I. Salama and J. Patel: "Ibotenic Acid Mediates
Neurotoxicity and Phosphoinositide Hydrolysis by Independent Receptor Mechanisms"
MOL CHEM NEUROPATH 16:1-10.
W.C. Zinkand, P.A. DeFeo, C. Thompson, H.M. Hargrove, A.I. Salama and J. Patel:
"Quisqualate Neurotoxicity in Rat Cortical Cultures: Pharmacology and Mechanisms" EUR
J PHARM 212:129-136.
W.C. Zinkand, C. Thompson,A.I. Salama and J. Patel: "Excitatory Amino Acid-Evoked Calcium
Influx and Calcium-Dependent Neurotoxicity in Rat Cortical Cultures" ANN NY ACAD SCI
212:355-357.
W.C. Zinkand, R.J. Stumpo, C. Thompson, J. Patel and L.M. Pullan: "Lack of Involvement of
Nitric Oxide in NMDA-Induced Neuronal Cell Death in Cortical Culture" Neuroreport 5,
148-150.
ABSTRACTS
A.M. Corbett, W.C. Zinkand, B.K. Krueger: "Activation of Single Neuronal Sodium Channels by
Veratridine and Polypeptide Neurotoxins in Planar Lipid Bilayers" Biophysical Society.
S. Cukierman, W.C. Zinkand, R.J. French, B.K. Krueger: "Effects of Calcium and Lipid Surface
Charge of Sodium Channel Gating" Biophysical Society.
P. Dargis, C.A. Thompson, W. Zinkand, R. Kozel, J. Patel and R.C. Falcone: "The Signal
Capacitance Calcium Entry is not Mediated by Cytochrome p450 Inhibition" FASEB J,
1994.
J. Patel, W.C. Zinkand, W.C. Moore, A.I. Salama: "Ibotenic Acid is Similar to N-Methyl-D-
Aspartate in Cytotoxicity but Similar to Quisqualate in Phosphoinositide Hydrolysis
Enhancement in Rat Cortical Cultures" Society for Neuroscience.
L.M. Pullan, R.J. Stumpo, M. Britt, M.J. Chapdelaine, R.A. Keith, D. LaMonte, T.J. Mangano, J.
Patel, R.J. Powel, P.J. Warwick, W.C. Zinkand and A.I. Salama: "In-Vivo and In-Vitro
2. Stereoselectivity of the Glycine Site of the NMDA Receptor for the (R)-Enantiomer of HA-
966" Society for Neuroscience Abs 16(2) #430.1.
P.J. Yarowski, W.C. Zinkand, R. Johnson, B.K. Krueger: "Development of Na+
Channels in Rat
Cerebral Astrocytes "Binding of [3
H]Saxitoxin to Cultured Astrocytes" FASEB Vol. 46 p.
504, 1987.
W.C. Zinkand, J. Patel, A.I. Salama: "Block of N-Methyl-D-Aspartate Neurotoxocity by Glycine
Antagonists in Cortical Cultures" Society for Neuroscience.
W.C. Zinkand, C. Thompson,A.I. Salama, J. Patel: "Excitatory Amino Acid Evoked Calcium
Influx and Calcium-Dependent Neurotoxicity in Rat Cortical Cultures, Society for
Neuroscience, 1990.
W.C. Zinkand, P.A. DeFeo, C. Thompson and J. Patel: "Delayed Quisqualate Neurotoxicity in
Rat Cortical Cultures" Society for Neuroscience Abs 17(1) #32.9.
W.C. Zinkand, R.J. Stumpo, C. Thompson, H.M. Hargrove, L.M. Pullan and J. Patel: "Nitric
Oxide is not Involved in NMDA-Induced Neurotoxicity in Rat Cortical Cultures" Society for
Neuroscience Abs.
W.C. Zinkand, E.J. Warawa, R.C. Falcone, J. Patel, E.P. Christian: "Dipyridyltriazoles: A Novel
Series of Store-Operated Calcium Channel Blockers" Biophysical Society Abs.