1. Publications (Author search: B. Easwaramoorthy, or E. Balasubramaniam)
2005-
1. P.M. Shikhaliev, T. Xu, J.L. Ducote, B. Easwaramoorthy, J. Mukherjee and S.
Molloi, Positron autoradiography for intravascular imaging: Feasibility
evaluation. Physics in Medicine and Biology 51, 963 (2006).
2. R. Pichika, B. Easwaramoorthy, D. Collins, B.T. Christian, B. Shi, T.K.
Narayanan, J. Mukherjee, Nicotinic 42 Receptor Imaging Agents. Part II.
Synthesis and Biological Evaluation of 2-[18F]Fluoro-3-[2-((S)-3-
Pyrrolinyl)Methoxy]Pyridine (18F-Nifene) in Rodents and Imaging by PET in
Non-human Primate. Nuclear Medicine Biology 33, 295 (2006).
3. N. Saigal, R. Pichika, B. Easwaramoorthy, D. Collins, B.T. Christian, B. Shi,
T.K. Narayanan and J. Mukherjee, Synthesis and biological evaluation of a
novel serotonin 5-HT1a receptor radioligand, N-{2-[4-(2-
methoxyphenyl)piperazinyl]ethyl}-N-(2-pyridyl)-N-(4-18
F-fluoromethylcyclo-
hexane)carboxamide (18
F-Mefway) in rodents and imaging by PET in non-
human primate. Journal of Nuclear Medicine 47, 1697 (2006).
4. B. Easwaramoorthy, R. Pichika, D. Collins S. Potkin and J. Mukherjee. The
effect of acetylcholinesterase inhibitors on 42 nAChR ligand, 18
F-Nifene: A
measure of acetylcholine competition. Synapse, 61, 29 (2007).
5. J. Mukherjee, E. Head, R. Pichika, B. Easwaramoorthy, D. Collins, I. Chen, C.
Wang, N. Saigal, P. Trinidad, K. Kim, V. Nguyen, Radiotracers for a multitarget
approach to the diagnosis of Alzheimer Disease. Journal of Labeled
Compounds and Radiopharmaceuticals 50, 375 (2007).
6. B. Easwaramoorthy, R. Coleman, C. Constantinescu, M.L. Pan, J.Mukherjee,
F-18-Nifene for quantification of alpha 4 beta 2 nicotinic receptors. Neuroimage
41, T181 (2008).
7. J. Mukherjee, G. Chandy, N. Milne, P. Wang, B. Easwaramoorthy, J. Mantil,
A. Garcia. Imaging Agents for Monitoring changes of Dopamine Receptors and
methods of using thereof. United States Patent 2008: US 12/110,135 (2008).
8. Z.A. Dreger, B. Easwaramoorthy, Y.M. Gupta, A.G. Joly, High-Pressure
Effects on the Electronic Structure of Anthracene Single Crystals: Role of
Nonhydrostaticity. Journal of Physical Chemistry 113, 1489 (2009).
9. S. Pandey, A. Shah, S. Panchal, B. Easwaramoorthy, C. Constantinescu, R.
Coleman, R. Kant and J. Mukherjee; Multimodality Imaging Probe for
Monitoring Cell Transplantation and Migration. Journal of Labeled Compounds
and Radiopharmaceuticals 52, S56 (2009).
10. M. Ichise, M. Slifstein, B. Easwaramoorthy, SA Bae, A. Carpenter, A. Maffei,
R. Van Heertum, H Kung and P Harris VMAT2 imaging of baboons with two
18F-FP-DTBZ enantiomers. Journal of Nuclear Medicine 50 1206 (2009).
2. 11. N. Ramesh, M. Palatnik, J. Rini, M. Slifstein, A. Abi-Dargham and B.
Easwaramoorthy, Dimerization of Phenols and Naphthols using Aqueouos
sodium hypochlorite. Tetrahedron Letters 51, 2497 (2010).
12. R. Girgis, X. Xu, N.Miyake, B. Easwaramoorthy, R. N. Gunn, E. A. Rabiner, A.
Abi-Dargham, M. Slifstein, In vivo binding of antipsychotics to D3 and D2
receptors: A PET study in baboons with [11C]-(+)PHNO.
Neuropsychopharmacology 36, 887 (2011).
13. N.Miyake, M. Skinbjerg, B. Easwaramoorthy, D. Kumar, R. Girgis, X. Xu, M.
Slifstein, A. Abi-Dargham, Imaging changes in glutamate transmission in vivo
with the metabotropic glutamate receptor 5 tracer [11C]ABP688 and N-
acetylcysteine challenge. Biological Psychiatry 69, 822 (2011).
14. K. Ridler, C. Plisson, E. A. Rabiner, R. N. Gunn, B. Easwaramoorthy, A. Abi-
Dargham, M. Laruelle and M. Slifstein. Characterisation of in vivo
pharmacological properties and sensitivity to endogenous serotonin of [11
C]
P943: a positron emission tomography study in Papio Anubis. Synapse 69,
1119 (2011).
15. R. Kant, C. Constantinescu, P. Parekh, S. Pandey, M. Pan, B.
Easwaramoorthy, J. Mukherjee. Evaluation of 18F-Nifene Binding to α4β2
Nicotinic Receptors in the Rat Brain using MicroPET Imaging. European
Journal of Nuclear Medicine and Molecular Imaging Research 1, 6 (2011).
16. R. Pichika, B. Easwaramoorthy, B.T. Christian, B. Shi, T.K. Narayanan, D.
Collins, and J. Mukherjee. Nicotinic 42 Receptor Imaging Agents. Part III.
Synthesis and Biological Evaluation of 5-(3'-18F-Fluoropropyl)-3-(2-(S)-
Azetidinylmethoxy)Pyridine (18F-Nifzetidine). Nuclear Medicine Biology 38,
1183 (2011).
17. R. Pichika, S. A. Kuruvilla, N.Patel, K. Vu, S. Sinha, B. Easwaramoorthy, T. K.
Narayanan, B. Shi, B. Christian and J. Mukherjee. Nicotinic 42 receptor
imaging agents. Part IV. Synthesis and Biological Evaluation of 3-(2-(S)-3,4-
dehydropyrrolinylmethoxy)- 5-(3’-18F-Fluoropropyl)pyridine (18F-Nifrolene)
using PET. Nuclear Medicine Biology 40, 117 (2013).
18. M. Farwell, D. Chong, Y. Iida, S.A. Bae, B. Easwaramoorthy, M. Ichise,
Imaging P-glycoprotein function in rats using [¹¹C]N-desmethyl-loperamide.
Annual Nuclear Medicine 27, 618 (2013).
19. S.K. Pandey, J. Kaur, B. Easwaramoorthy, A. Shah, R. Coleman, J.
Mukherjee Multimodality Imaging Probe for PET and Fluorescence Imaging.
Molecular Imaging 13, 1 (2014).
20. D.R. Hwang, E. Hu, S. Rumfelt, B. Easwaramoorthy, J. Castrillon, C. Davis,
J.R. Allen, H. Chen, J. Treanor, A. Abi-Dargham, M. Slifstein. Initial
characterization of a PDE10A selective positron emission tomography tracer
[11C]AMG 7980 in non-human primates. Nuclear Medicine Biology 41, 343
(2014).
3. 21. B. Easwaramoorthy, N. Ramesh, M. Palatnik, M. Slifstein, A. Abi-Dargham.
Synthesis and evaluation of 2-chloro-7-[C-11]methyl-6a,7,8,12b-tetrahydro-6H-
chromeno[3,4-c]isoquinolin-3-ol as a PET ligand for Dopamine D1 receptor
agonism. Nuclear Medicine Biology (In review).
22. B. Easwaramoorthy, R. Neelamegam, R. K. Patti, M. T. Palatnik, J. Myung, B.
Feng, A. Abi-Dargham. Synthesis and biological evaluation of 2-chloro-
6a,7,8,12b-tetrahydro-6H-chromeno[3,4-c]isoquinolin-3-ol hydrochloride
derivatives. Bioorganic & Medicinal Chemistry Letters (Required Reviews
Completed).
23. B. Easwaramoorthy, D. Balachari, N. Ramesh, M. Slifstein, A. Abi-Dargham.
Design and synthesis of novel 18F-diazabicyclo[3.2.2]nonane for imaging
nictonic a7 receptors. (To be submitted).
1992 - 2005
24. V. Paul, E. Balasubramaniam, P. Muthu and M. Krishnamoorthy, Evidence for
a hazardous Interaction between Ethanol and the Insecticide Endosulfan in
Rats. Pharmacology Toxicology 70, 268 (1992).
25. V. Paul, E. Balasubramaniam, S. Sheela and M.S. Krishnamoorthy, Effects of
Endosulfan and Aldrin on Muscle Coordination and Conditioned Avoidance-
Response in Rats. Pharmacology Toxicology 71, 254 (1992).
26. V. Paul, S. Sheela, E. Balasubramaniam and M. Kazi, Behavioural and
Biochemical changes produced by repeated Oral administration of the
insecticides Endosulfan in Immature rats. Indian Journal of Physiology and
Pharmacology 37, 204 (1993).
27. V. Paul, M. Kazi, E. Balasubramaniam and S. Sheela, Effect of Chronic
Endosulfan Treatment on Pharmacological Actions of Diazepam in Rats.
Bulletin of Environmental Contamination and Toxicology 51, 18 (1993).
28. V. Paul, E. Balasubramaniam and M. Kazi, The Neurobehavioral Toxicity of
Endosulfan in Rats – A Serotonergic Involvement in Learning Impairment.
European Journal of Pharmacology and Environmental Toxicology
Pharmacology 270, 1 (1994).
29. V. Paul, E. Balasubramaniam and M. Kazi, Alteration in the Tranquilizing
Potency of Chlorpromazine in Rats Exposed Chronically to the Insecticide,
Endosulfan. Bulletin of Environmental Contamination and Toxicology 53, 655
(1994).
30. V. Paul, E. Balasubramaniam, A.R. Jayakumar and M. Kazi, A Sex-Related
Difference in the Neurobehavioral and Hepatic-Effects Following Chronic
Endosulfan Treatment in Rats. European Journal of Pharmacology and
Environmental Toxicology Pharmacology 293, 355 (1995).
4. 31. E. Balasubramaniam, V. Paul and M. Kazi, Cyclodiene Inscticides-induced
changes in the central Depressive effect of Chlorpromazine in Rats. Indian
Journal of Physiology and Pharmacology 39, 231 (1995).
32. E. Balasubramaniam, G. Ramachandraiah, P. Natarajan, C. Bied Charreton,
J. Devynck and F. Bedioui, Electrochemical Preparation of Anthraquinone and
Zinc Porphyrin Coated Electrodes - Redox Activity and Film Stability. Journal of
Materials Chemistry 4, 625 (1995).
33. E. Balasubramaniam, V. Paul, A.R. Jayakumar and M. Kazi, The Effect of
Chronic Cyclodiene Insecticide Treatment on Some Pharmacological Actions of
Diazepam in Rats. Environmental Toxicology Pharmacology 1, 141 (1996).
34. E. Balasubramaniam and P. Natarajan, Photophysical Properties of
Protoporphyrin-IX and Thionine Covalently Attached to Macromolecules.
Journal of Photochemistry and Photobiology A:Chemistry 103, 201 (1997).
35. E. Balasubramaniam and P. Natarajan, Photoelectrochemical Studies on
Electrodes Coated with Polymer-Bound Porphyrin Systems. Journal of
Photochemistry and Photobiology A:Chemistry 109, 39 (1997).
36. V. Paul and E. Balasubramaniam, Effects of Single and Repeated
Administration of Endosulfan on Behavior and Its Interaction with Centrally
Acting Drugs in Experimental-Animals – A Mini Review. Environmental
Toxicology Pharmacology 3, 151 (1997).
37. D. Chatterjee and E. Balasubramaniam, Photo-Assisted Electron-Transfer in a
Nickel(II) Porphyrin Complex – Formation of Nickel(II)-Porphyrin Pi-Cation
Radical. Journal of Co-ordination Chemistry 46, 467 (1999).
38. I.Y. Wu, J.T. Lin, Y.T. Tao and E. Balasubramaniam, Starburst molecules
based upon Hexathienyl benzene units: Potential Hole Transporting material.
Advanced Materials 12, 668 (2000).
39. Y. T. Tao, E. Balasubramaniam, A. Danel and P. Tomsik, Dipyrazolopyridine
Derivatives as Bright Blue Electroluminescent Materials. Applied Physics
Letters 77, 933 (2000).
40. Y. T. Tao, E. Balasubramaniam, A. Danel, B. Jarosz and P. Tomsik, Sharp
Green Electroluminescence from 1H-Pyrazolo[3,4-b]quinoline based Light-
Emittting diodes. Applied Physics Letters 77, 1575 (2000).
41. E. Balasubramaniam, Y. T. Tao, A. Danel and P. Tomsik, Blue Light-Emitting
Diodes Based on Dipyrazolopyridine derivatives. Chemistry of Materials 12,
2788 (2000).
42. C.T. Chen, Y.J. Lin, L.H. Jan, H.C. Yeh, E. Balasubramaniam, and Y.T. Tao,
Teraphenylmethane-Based 1,3,4-Oxadiazole with High Glass Transition
Temperatures for Electron Transporting Materials in Organic Light-Emitting
Devices. Materials Research Society Proceedings 598, BB3.5.1 (2000).
5. 43. Y. T. Tao, E. Balasubramaniam, A. Danel, A. Wisla and P. Tomasik,
Pyrazoloquinoline Derivatives as Efficient Blue Electroluminescent Materials.
Journal of Materials Chemistry 11, 768 (2001).
44. Y.T. Tao, E. Balasubramaniam, A. Danel, B. Jarosz and P. Tomasik, Organic
Light-Emitting Diodes Based on variously substituted Pyrazoloquinolines as
emitting material. Chemistry of Materials 13, 1207 (2001).
45. I.Y. Wu, J.T. Lin, Y.T. Tao, E. Balasubramaniam, Y.Z. Su and C.W. Ko
Diphenylthienylamine-Based Star Shaped Molecules for Electroluminescence
Application. Chemistry of Materials 13, 2626 (2001).
46. H.C. Yeh, R.H. Lee, L.S. Chan, T.Y.J. Lin, C.T. Chen, E. Balasubramaniam
and Y.T. Tao, Synthesis, Properties, and Applications of Tetraphenylmethane-
based Molecular Materials for Light-emitting Devices. Chemistry of Materials
13, 2788 (2001).
47. Y.T. Tao, C.W. Ko and E. Balasubramaniam, Energy Transfer vs. Carrier
Trapping: Emission Mechanism in Dye-doped Organic Light Emitting diodes.
Thin Solid Films 417, 61 (2002).
48. J.P.J. Markham, S.-C. Lo, T.D. Anthopoulos, N.H. Male, E. Balasubramaniam,
O.V. Salata, P.L. Burn and I.D.W. Samuel, Highly Efficient solution-processible
Phosphorescent Dendrimers for Organic Light Emitting Diodes. Journal of
Society for Information Display 11, 161 (2003).
49. J.T. Lin, I.Y. Wu, Y.T. Tao and E. Balasubramaniam. Hetarylbenzene
Compounds United States Patent, US 6,512,122 B2, Jan. 28, 2003.
50. T. Besanger, B. Easwaramoorthy and J.D. Brennan, Entrapment of Highly
Active Membrane-Bound Receptors in Macroporous Sol-Gel Derived Silica.
Analytical Chemistry 76, 6470 (2004).