1. Marc V. Fuccillo, M.D. / Ph.D.
CURRICULUM VITAE
Perelman School of Medicine
Department of Neuroscience
415 Curie Blvd
Clinical Research Building, Room 226
Philadelphia, PA 19104 USA
Cell Phone: (646) 483-6714
Lab Phone: (215) 898-8744
E-mail: fuccillo@mail.med.upenn.edu
EDUCATION
2008 Doctor of Medicine (M.D.), New York University School of Medicine,
New York, New York.
2007 Doctor of Philosophy (Ph.D.), Developmental Genetics, New York
University School of Medicine, New York, New York.
Advisor: Dr. Gordon J. Fishell.
1998 Bachelor of Arts (B.A.) with honors, Brown University, Providence, Rhode
Island.
Focus: Molecular and Cellular Biology, Minor: Music Performance (Violin)
Honors Research Advisor: Dr. Alan Rosmarin.
POSTGRADUATE TRAINING
2008-2014 Postdoctoral Training, Advisors: Robert C. Malenka, Tom C. Südhof
Circuit and electrophysiological analyses of abnormal behavioral control
in mouse models of autism spectrum disorders.
Department of Psychiatry and Behavioral Sciences, Stanford University
School of Medicine
APPOINTMENTS
2015-2021 Assistant Professor, Department of Neuroscience, Perelman School of
Medicine, University of Pennsylvania
SELECTED HONORS AND AWARDS
2012-2017 NIH Pathway to Independence Award (K99/R00), “Linking Synaptic and
Cognitive Deficits in a Model of Neuropsychiatric Disease,” NIMH Grant
Number: K99MH099243
2008-2011 Ruth L. Kirschstein National Research Service Award (NRSA) for Individual
Postdoctoral Fellows (F32), “Synaptic Analysis of Neuroligin1 function,” NIMH
Grant Number: F32MH086176
2. Marc V. Fuccillo, M.D. / Ph.D.
CURRICULUM VITAE
2008 Alpha Omega Alpha (AOA) honor society, New York University School of
Medicine
1998 Honors Degree in Biology, Brown University
1997 Brown University Undergraduate Teaching and Research Fellowship Award,
Brown University
MEETINGS WITH PRESENTATIONS
Feb 2014 1st
Gordon Research Conference on Basal Ganglia Cells and Circuits in
Health and Disease, Ventura, CA. Invited talk: “Autism Associated
Neuroligin-3 Mutations Impair Striatal Circuits Underlying Repetitive
Behaviors.”
Nov 2013 43rd
annual meeting of the Society for Neuroscience, San Diego, CA.
Nanosymposium on Medium Spiny Neuron Diversity and Striatal Function,
talk entitled “Linking abnormal behavioral regulation with alterations in striatal
neurotransmission in the Neuroligin3 mouse model of autism.”
July 2010 Gordon Research Conference on Synaptic Transmission, Biddeford, ME.
Nov 2007 36rd
annual meeting of the Society for Neuroscience, San Diego, CA.
Barrels XX Satellite Meeting, La Jolla, CA.
July 2006 Gordon Research Conference on Neural Development, Newport, RI.
Aug 2005 MSTP Annual MD/PhD Student Conference, Keystone, CO.
July 2004 Gordon Research Conference on Neural Development, Newport, RI.
PUBLICATIONS
Rothwell P.E.*, Fuccillo M.*, Maxeiner S., Hayton S.J., Lim B.K., Malenka R.C., Südhof T.C.
(2014) Autism-Associated Neuroligin-3 Mutations Disrupt Striatal Circuits Underlying
Repetitive Motor Routines. Cell, 158(1): 198-212. PMID: 24995986
*these authors contributed equally to this publication.
Fuccillo M*., Földy C*., Gökce O., Malenka R.C., Südhof T.C. Characterization of circuit
diversity through single neuron analysis of Neurexin expression. Manuscript submitted,
Neuron.
*these authors contributed equally to this publication.
Soler-Llavina G.J.*, Fuccillo M.*, Ko J., Südhof T.C., Malenka R.C. (2011) The neurexin
ligands, neuroligins and leucine-rich repeat transmembrane proteins, perform convergent
3. Marc V. Fuccillo, M.D. / Ph.D.
CURRICULUM VITAE
and divergent synaptic functions in vivo. Proceedings of the National Academy of Sciences,
108(40): 16502-509. PMID: 21953696
*these authors contributed equally to this publication.
Ko J., Soler-Llavina G.J., Fuccillo M., Malenka R.C., Südhof T.C. (2011) Neuroligins/
LRRTMs prevent activity- and Ca2+/calmodulin-dependent synapse elimination in cultured
neurons. J Cell Biol, 194(2): 323-34. PMID: 21788371
Zhang C., Atasoy D., Araç D., Yang X., Fuccillo M., Robison A.J., Ko J., Brunger A.T.,
Südhof T.C. (2010) Neurexins physically and functionally interact with GABA(A) receptors.
Neuron, 66(3): 403-16. PMID: 20471353
Ko J., Fuccillo M., Malenka R.C., Südhof T.C. (2009) LRRTM2 functions as a neurexin
ligand in promoting excitatory synapse formation. Neuron, 64(6): 791-8. PMID: 20064387
Butt, S.J.B.*, Sousa V.*, Fuccillo, M., Hjerling-Leffler, J., Miyoshi, G., Kimura, S., Fishell, G.
(2008) The requirement of Nkx2.1 in the temporal specification of cortical interneuron
subtypes. Neuron, 59(5): 722-32. PMID: 18786356
*these authors contributed equally to this publication.
Fuccillo, M., Joyner A.L., and Fishell G. (2006) Morphogen to mitogen: the multiple roles of
hedgehog signaling in vertebrate neural development. Nature Reviews Neuroscience 7(10):
772-783. PMID: 16988653
Butt, S. J. B.*, Fuccillo, M.*, Nery, S., Noctor, S., Kriegstein, A., Corbin, J.G., Fishell G.
(2005) The temporal and spatial origins of cortical interneurons predict their physiological
subtype. Neuron 48(4): 591-604. PMID: 16301176
*these authors contributed equally to this publication.
Fuccillo, M., Rallu, M., McMahon A.P., and Fishell G. (2004) Temporal Requirement for
Hedgehog Signaling in Ventral Telencephalic Patterning. Development 131(20): 5031-
5040. PMID: 15371303
Henriksen, M.A., Betz A., Fuccillo, M., and Darnell, J.E. (2002) Negative Regulation of
STAT92E by an N-terminally truncated STAT protein derived from an alternative promoter
site. Genes & Dev. 16(18): 2379-2389.