This presentation was provided by Keith Webster of Carnegie Mellon University during the two-day "NISO Tech Summit: Reflections Upon The Year of Open Science." Day one was held on October 25, 2023.

1. NISO Roundtable
Open science and
libraries
Keith Webster
Helen and Henry Posner Jr. Dean’s Chair
Dean of University Libraries
Director of Emerging and Integrative Media Initiatives
OCTOBER 25, 2023

3. “
The conversation gains momentum
Much of the remarkable growth of scientific
understanding in recent centuries is due to open
practices; open communication and deliberation
sit at the heart of scientific practice. Publishing
scientific theories, including experimental and
observational data, permits others to scrutinise
them, to replicate experiments and to reuse data
to create further understanding.
The Royal Society, 2012

5. “
The COVID Effect
The global COVID-19 health crisis has proven
worldwide the urgency of and need for fostering
equitable access to scientific information,
facilitating the sharing of scientific knowledge,
data and information, enhancing scientific
collaboration and science- and knowledge-based
decision making to respond to global
emergencies and increase the resilience of
societies.
Unesco, 2021
UNESCO Recommendation
on Open Science
OPEN
SCIENCE

8. Transparent and Reproducible Workflows

9. www.companyname.com
© 2016 Jetfabrik Multipurpose Theme. All Rights Reserved.
9

10. www.companyname.com
© 2016 Jetfabrik Multipurpose Theme. All Rights Reserved.
10

11. a) We pay to support preprint servers eg arXiv
b) We provide the KiltHub service powered by Figshare
for open access article sharing
c) We provide financial support for gold open access
article fees
d) We negotiate open access agreements with
commercial and society publishers to allow all articles
with a CMU corresponding author to be published
open access with no further fee payable
OA: Our Approach

12. 12
TARGET
PUBLISHERS
We set out to focus on
our leading publishers
by volume, but open to
agreements form other
publishers where terms
w e r e a t t r a c t i v e o r
business models were
innovative.
Source: Dimensions
72%
2016-2018

13. 13
OA
AGREEMENTS
TIMELINE :
Work began in 2018, with
n e g o t i a t i o n s t a k i n g p l a c e
throughout 2019. Our first
agreements took effect 1 Jan
2020
2020 2020 2020

14. 14
2021 2023 2023
2022 2023

15. • KiltHub: An approved generalist repository for
meeting mandated data sharing requirements and
sharing the products of research
• DMPTool: Template platform for creating data
management plans that meet funder requirements
• Data management services: Guidance and support
for writing DMPs and managing data effectively
Data Management

19. Carpentries
https://carpentries.org/
Leveraging Open Data for the Public Good: An Interview with Dr. Bill Sermons, Adjunct Faculty at CMU Heinz College, by Lencia Beltran
Training

20. Libraries Workshops
Open Science Workshops
Training

22. Collaborative bioinformatics
hackathons
● goal is to rapidly create and
publish an open-source
solution to a clinical
problem
Rapid Prototyping

24. https://cmu-lib.github.io/OSS/

27. Software as a primary research object

29. CMU Cloud Lab
• Remote controlled laboratory
• Automated instrumentation + technicians
• Everything traceable  reproducible science
• On site synthesis and/or samples sent to lab
• Based on Emerald Cloud Lab facility/partnership

30. Example Workflow 1
1.Solid Phase Peptide Synthesis
2.Reverse-phase prep HPLC purification
3.QC by MALDI mass spectrometry & analytical HPLC re-injection
4.Bioconjugation chemistry on a liquid handler
5.Fluorescence kinetics binding assay in a cell-free environment
Example Workflow 2
1.Precipitation conditions screening on a liquid handler
2.Validate by sample imaging
3.Isolate powder by filtration and wash
4.Dry on spin vacuum
5.Further characterization on power XRD
Example Workflow 3
1.DNA oligomer synthesis
2.Purification zby ion exchange HPLC with faction collection
3.MALDI all fractions and pool desired aliquots
4.Freeze and lyophilize fractions
5.UV melting experiments
User-designed scripts allow complex
workflows

31. Productivity
Open Science Active Learning
Reproducibility
How Will the Cloud Lab Transform Science?