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SEEDS
Pharmacognosy 2
PG- 216
You do remember that
Pharmacognosy is a science
that deals with natural
products, don’t you?
In the first year, we studied
Different organs of plants as
Leaves, Barks, Flowers…
etcetra
And now we will study…
Seeds
The seeds like
Comes after fertilization of ovule by the Pollen
grain.
It is an integumented fertilized ovule specialized for the distribution and continuation of
the plant.
Seeds
Distribution
Continuation
Types of ovules
Anatropous ovule
Structure of the Seed
Albuminous
Exalbuminous
Forms of Embryo
1- Straight embryo: as in Linseed.
2- Curved embryo
3- Bent
a- Accumbent the radicle is bent against the two flat cotyledons as in
fenugreek seed.
b- Incumbent the radicale is bent against the flat surface of the one of the 2
cotyledons.
c- Orthoplocus it is an incumbent in which the 2 cotyledons are bent to include
radicle in between as in Mustard seeds.
Let’s Start…..
LINSEED (FLAXSEED)
‫الكتان‬ ‫بذور‬
Dried ripe seed of Linum usitatissimum fam. Linaceae.
• Oval lanceolate.
• Mucilaginous oily taste.
• Characteristic odor.
• Glossy brown with minutely pitted surface and mucilagenous taste.
• Distinct yellow ridge (raphe) and slight depression near ! Pointed end (?).
Type of seed: Albuminous.
Type of ovule: Anatropous
Type of embryo: straight
T.S. in linseed
Powdered Linseed
Pigment layer of linseed
Powder of Linseed
Pigment layer
Sclerides
Active constituents
 Fixed oils.
 mucilage (pectose).
 Small amount of Cyanogenic glycosides
(linamarin).
 Omega-3 fatty acids.
 Tannin.
 protein, starch.
Uses
• It is used as demulcent drink and in
treatment of constipation.
• It contain omega-3 fatty acid. Antioxidants,
flaxseed can also help lower the risk of
diabetes, cancer, and heart disease.
• Lowering cholesterol.
• In painting.
Test for linamarin glycoside
(Guignard paper test)
Guignard paper:
(Filter paper moistened with aqueous
solution of picric acid, then allowed to dry
and dipped in aqueous solution of sodium
bicarbonate and dried).
Complete the following:
1- Linseed derived from ---- ------- ovule.
2- Uses o Linseed -----------------------, --------------------- and
------------------------.
3- Number of integuments of Linseed --------------.
4- Type of mucilage in linseed is ----------------.
5- Chemical test of Linseed
anatropus
demulcent drink treatment of
constipation
antioxidant
two
pectose
Guignard paper test
 Type of seed-----------------.
 Type of ovule-----------------.
 Test of mucilage ---------------
 Pressing between 2 f.p-------
----.
 Type of embryo-------------.
Try this eXercise:
albuminous.
anatropous
permanent stain
straight
ruthenium red
Nux vomica seed
Dried ripe seed of Strychnos nux-vomica fam. Loganiaceae.
• Disc- shaped (button) usually concave on one side and
convex on the other.
• Satiny sheen appearance (due to closely appressed hairs
radiating from the centre to the circumference).
• The presence of raised ridge or false raphae from
the micropyle to the center at the hilum position.
• It has a small embryo, formed of two small thin
cordate cotyledons.
• Odorless with intensely bitter and persistent
taste.
• Type of seed: Albuminous, very hard & horny.
• Type of ovule: atropous.
• Type of embryo: straight.
 Testa: one integument.
 Epidermis: thick lignified closely appressed
hairs with lignified ribs.
 Endosperm: horny, hemicellulosic
very thick-walled polyhedral cells connected
together by plasmodesma threads.
Microscopical characters
Powder of Nux vomica seed
Constituents
indole alkaloids
 Strychnine
 Brucine
Hemicellulose (endosperm)
Uses:
 Strychnine increases blood pressure; therefore, it is
given in cardiac failure and may be used as a
circulatory stimulant.
 May be used as a respiratory stimulant in certain
cases of poisoning.
 Strychnine was formerly used as a bitter tonic &
stomachic, improving appetite and digestion.
 CNS stimulant in barbiturates poisoning.
 Poison for rats and other animals, used as
rodenticide.
Chemical tests
 Brucine +fuming HNO3 = Orange red color
 Strychnine + Mandalin’s reagent (sulfovanidic
acid)= violet
 Hemicellulose +I2 /sulfuric acid=bluish violet
• Nux Vomica is known as poison nut or vomiting nut.
• Strychnine is one of the bitterest substances known.
• Strychnine is highly toxic, affecting the CNS inducing
convulsions (severe muscular spasms), death occurs from
asphyxia due to convulsions of the respiratory muscles.
.
We will see the effects of strychnine
On mice in pharmacology lab.
Do You
Know!!
Try to figure out the errors in these sentences, if present?
• Type of ovule in Nux vomica seed is anatropous, as it shows
raphe.
• Linseed showed false raphe.
• Strychnine alkaloid gives violet color with conc. HNO3.
• Linseed can be used as respiratory stimulant.
Complete the following sentences?
• A transverse section in Nux vomica mounted with
Mandelin's reagent, a violet color is produced in the-------
--------------------------------of endosperm.
• Nux vomica seed has --------------- shaped
Linseed has ------------ integument(s), while nux vomica
seed has ---------- integument(s).
• Nux vomica seeds have Satiny sheen appearance due
to the presence of -----------------------------------.
• The epidermis of linseed is ------------------------- while in
Nux vomica seeds is-----------------.
Hemicellulose
button
2
1
thick lignified closely appressed hairs with lignified ribs
Parenchymatous
schlerenchymatous
seed 1.pdf

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seed 1.pdf

  • 2. You do remember that Pharmacognosy is a science that deals with natural products, don’t you? In the first year, we studied Different organs of plants as Leaves, Barks, Flowers… etcetra
  • 3. And now we will study… Seeds
  • 4. The seeds like Comes after fertilization of ovule by the Pollen grain.
  • 5. It is an integumented fertilized ovule specialized for the distribution and continuation of the plant. Seeds
  • 8. Structure of the Seed Albuminous Exalbuminous
  • 9. Forms of Embryo 1- Straight embryo: as in Linseed. 2- Curved embryo 3- Bent a- Accumbent the radicle is bent against the two flat cotyledons as in fenugreek seed. b- Incumbent the radicale is bent against the flat surface of the one of the 2 cotyledons. c- Orthoplocus it is an incumbent in which the 2 cotyledons are bent to include radicle in between as in Mustard seeds.
  • 11. LINSEED (FLAXSEED) ‫الكتان‬ ‫بذور‬ Dried ripe seed of Linum usitatissimum fam. Linaceae.
  • 12.
  • 13. • Oval lanceolate. • Mucilaginous oily taste. • Characteristic odor. • Glossy brown with minutely pitted surface and mucilagenous taste. • Distinct yellow ridge (raphe) and slight depression near ! Pointed end (?). Type of seed: Albuminous. Type of ovule: Anatropous Type of embryo: straight
  • 16.
  • 17. Pigment layer of linseed
  • 18. Powder of Linseed Pigment layer Sclerides
  • 19. Active constituents  Fixed oils.  mucilage (pectose).  Small amount of Cyanogenic glycosides (linamarin).  Omega-3 fatty acids.  Tannin.  protein, starch.
  • 20. Uses • It is used as demulcent drink and in treatment of constipation. • It contain omega-3 fatty acid. Antioxidants, flaxseed can also help lower the risk of diabetes, cancer, and heart disease. • Lowering cholesterol. • In painting.
  • 21. Test for linamarin glycoside (Guignard paper test)
  • 22. Guignard paper: (Filter paper moistened with aqueous solution of picric acid, then allowed to dry and dipped in aqueous solution of sodium bicarbonate and dried).
  • 23. Complete the following: 1- Linseed derived from ---- ------- ovule. 2- Uses o Linseed -----------------------, --------------------- and ------------------------. 3- Number of integuments of Linseed --------------. 4- Type of mucilage in linseed is ----------------. 5- Chemical test of Linseed anatropus demulcent drink treatment of constipation antioxidant two pectose Guignard paper test
  • 24.  Type of seed-----------------.  Type of ovule-----------------.  Test of mucilage ---------------  Pressing between 2 f.p------- ----.  Type of embryo-------------. Try this eXercise: albuminous. anatropous permanent stain straight ruthenium red
  • 25. Nux vomica seed Dried ripe seed of Strychnos nux-vomica fam. Loganiaceae.
  • 26. • Disc- shaped (button) usually concave on one side and convex on the other. • Satiny sheen appearance (due to closely appressed hairs radiating from the centre to the circumference).
  • 27. • The presence of raised ridge or false raphae from the micropyle to the center at the hilum position. • It has a small embryo, formed of two small thin cordate cotyledons. • Odorless with intensely bitter and persistent taste. • Type of seed: Albuminous, very hard & horny. • Type of ovule: atropous. • Type of embryo: straight.
  • 28.  Testa: one integument.  Epidermis: thick lignified closely appressed hairs with lignified ribs.  Endosperm: horny, hemicellulosic very thick-walled polyhedral cells connected together by plasmodesma threads. Microscopical characters
  • 29.
  • 30.
  • 31. Powder of Nux vomica seed
  • 32. Constituents indole alkaloids  Strychnine  Brucine Hemicellulose (endosperm)
  • 33. Uses:  Strychnine increases blood pressure; therefore, it is given in cardiac failure and may be used as a circulatory stimulant.  May be used as a respiratory stimulant in certain cases of poisoning.  Strychnine was formerly used as a bitter tonic & stomachic, improving appetite and digestion.  CNS stimulant in barbiturates poisoning.  Poison for rats and other animals, used as rodenticide.
  • 34. Chemical tests  Brucine +fuming HNO3 = Orange red color  Strychnine + Mandalin’s reagent (sulfovanidic acid)= violet  Hemicellulose +I2 /sulfuric acid=bluish violet
  • 35. • Nux Vomica is known as poison nut or vomiting nut. • Strychnine is one of the bitterest substances known. • Strychnine is highly toxic, affecting the CNS inducing convulsions (severe muscular spasms), death occurs from asphyxia due to convulsions of the respiratory muscles. . We will see the effects of strychnine On mice in pharmacology lab. Do You Know!!
  • 36. Try to figure out the errors in these sentences, if present? • Type of ovule in Nux vomica seed is anatropous, as it shows raphe. • Linseed showed false raphe. • Strychnine alkaloid gives violet color with conc. HNO3. • Linseed can be used as respiratory stimulant.
  • 37. Complete the following sentences? • A transverse section in Nux vomica mounted with Mandelin's reagent, a violet color is produced in the------- --------------------------------of endosperm. • Nux vomica seed has --------------- shaped Linseed has ------------ integument(s), while nux vomica seed has ---------- integument(s). • Nux vomica seeds have Satiny sheen appearance due to the presence of -----------------------------------. • The epidermis of linseed is ------------------------- while in Nux vomica seeds is-----------------. Hemicellulose button 2 1 thick lignified closely appressed hairs with lignified ribs Parenchymatous schlerenchymatous