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STUDIES AND UPGRADES ON THE C70 CYCLOTRON ARRONAX
F. Poirier, S. Girault, Arronax, Saint-Herblain, and CNRS – DR17, Rennes France
F.Bulteau Harel, J.B. Etienne, X.Goiziou, F. Gomez, A.Herbert, L.Lamouric, D. Poyac, H.Trichet,
Arronax, Saint-Herblain, France
C. Huet, Arronax, Saint-Herblain, and EMN, Nantes, France
E. Mace, Arronax, Saint-Herblain, and INSERM, Nantes, France
Abstract
The multi-particle cyclotron C70 Arronax is fully
running since 2010 and its RF run time has increased up
to 4400 hours in 2015. The accelerator is used for a wide
variety of experiments (physics cross-sections, radiolysis,
radiobiology) and radio-isotope productions. This
requires runs with 7 orders of intensity range from a few
pA up to 350 A and a large range of particles energy.
Machine and beamline studies are continuously needed.
For example magnet intensity scan inside the cyclotron
and in the beamlines, respectively with compensation
coils and the quadrupoles have been done. These scans
caracterise performances of the machine and help both
operations and mitigation of particle losses. Additionally
beam loss monitors and control systems are being devised
to support further the high intensity and precision
requirements on the runs. Also a pulsed train alpha beam
system located in the injection has been designed. The
proof of principle with a dedicated run has been
performed.
The results of the machine studies and status of these
developments are presented in this paper.
INTRODUCTION
The cyclotron Arronax [1] (Accelerator for Research in
Radiochemistry and Oncology at Nantes Atlantique),
running since 2010, the year of its commissioning, has
started in 2011 its hands-on phase [2]. Arronax has
gradually increased the number of hours it uses the
cyclotron.
The cyclotron delivers beams separately in six vaults
surrounding the main cyclotron vault [3]. Five of the
vaults are used for high intensity beams and the sixth one,
beamline for experiments, is dedicated to low and ultra-
low intensity (<100 electric pA).
The priority list for production of radio-isotopes covers
both isotopes for imaging and therapy. It includes, but not
exclusively, 82
Sr, 64
Cu, 211
At and 166
Ho. 211
At requires an
energy degrader that has been installed in one of the
beamline and as for 166
Ho, a neutronic activator is in use,
all at intensities above 10A.
RANGE OF OPERATION
The cyclotron provides four types of positively charged
particles (proton, alpha, deuterons, HH+) which intensity
and energy can be modified according to the experimental
needs. Figure 1 shows a map of the operation range for
each particle at intensity from a few nA up to 100s of A
on the target with energies from 32 MeV up to 70.3 MeV
for protons. Protons and deuterons have the widest energy
range mainly due to cross-section measurements being
performed at Arronax on numerous physics production
channels [4]. Several runs with protons for 82
SR
production have started in 2016 at 150A on target,
extending the production capacities at Arronax.
Figure 1: The operation range for the C70 Arronax with
the 4 particles in use.
THE MACHINE OPERATION
The use of the cyclotron, here expressed in term of
number of RF hours, has increased over the years up to
4400h in 2015 as shown in Fig.2, being limited mostly by
manpower. Each year includes 4 main preventive
maintenances that are performed over a week. Also, a
Computerized Maintenance Management System
(CMMS) – MaintiMedia from Tribofilm, is in place since
2015, to support the general maintenance follow-ups.
Figure 2: RF accumulated time per year since 2011 and as
of august for 2016 and estimation for this year.
The settings on the machine parameters at the
beginning of a run are systematically adjusted to increase
the transmission rate and as the operation last and
magnets elements temperature increase, parameters such
as main coils are optimised. In the case of new beam
parameters e.g. new particle energy and/or intensity, being
developed, systematic studies are planned.
The studies include transmission rate and also scans
with various settings on the machine as shown later.
Table 1: Transmission Rate for the 3 Main Particles
Particles Estimated
Intensity in
cyclotron [A]
Transmission rate
(End-of_line/injection)
H+ 252 43%
D+ 64 37%
He2+ 26.6 10%
The transmission rate from the faraday in the injection
to the end-of-line is indicated in the table 1. The particles
losses are mainly in the injection and below 2 MeV.
Additional losses are along the trajectory in the cyclotron
(neutral particles at the level of 4.4% for protons) and
along the beamlines (a few percentage).
MACHINE OPERATION STUDIES
The cyclotron is constituted of several internal magnets
beside the main coil which provide the average magnetic
field for the valley and hills. These are 3 compensation
coils at 3 different radius (internal, medium and external)
and paired harmonic coils. While in a dual-beamline run,
the compensation ones are adjusted such that maximum
current is obtained at both exit and the harmonic ones are
set such that symmetry in intensity is observed. A scan of
the intensity on faraday cups at the extraction exit was
performed as a function of the compensation coils. The
result is plotted in Fig. 3 for the intensity as a function of
the external and medium coil and shows a region of
maximum transmission with a large stability area (red). It
also indicates some region to be avoided as a
discontinuity on the magnet elements is present when
passing 0A. This type of scan did show the need to
perform regular check with newly constructed sets of
magnet taking into account several multi-scan results.
This type of scan with the help of dedicated beamline
diagnostics can be used to track the status of the beam (eg
resonances in the machine leading to beam blow-up, and
modification of the beam shape) and stabilises overall
runs. Taking into account these scans will have to be
mitigated with the modification of the particles final
kinetic energy.
BEAMLINE OPERATION STUDIES
Emittance measurements are important for check of the
stability of the machine, determining focusing spots on
the target and losses in the beamlines. This is addressed
first though quadrupole scans in the beamlines.
Figure 3: Total extracted intensity [uA] on both-side
faraday cup as a function of compensation coils medium
and external settings.
Quadrupole scan have been performed at intensities
between 10 up to 30 A. These scans have the goal to
find the best setting for transmission rate in the beamline,
for adequate beam size at the target location, emittance
measurements studies and potential use in ballistic beam-
based alignment to optimise the trajectory of the beam
inside the beamline.
Figure 4: Quadrupole scan result with the 2 last
consecutive magnets in the beamline. The coloring
represents the interpreted intensity level on the
collimators in the horizontal plane and the black dots the
actual data points.
The scan of Fig. 4, was first obtained to select data that
could be used to perform first preliminary emittance
measurements. The criteria being two-fold: centered
position of the beam and a full shape containing a deep in
the scan. The chosen scan are indicated in Fig. 4. The
technique uses first a transformation of the signal on the
10 mm aperture radius collimator into beam dimension.
The fitted beam size is plotted as a function of strength in
the quadrupole setting. The parabola obtained is then
fitted to acquire the emittance according to:
�� = √��
�2⁄
Where A and C are parameters of the fitting parabola
[5] similar to single-wire scan and d is, a distance, here a
fixed conversion factor from the simulation model in use.
The technique is at the present time being tested for
robustness. It relies on simulations model with
G4Beamline [6] for the transformation of the signal on
the collimator to a beam size. The first measurements
indicated variation in the emittance by a factor of 4 for
runs separated by a few weeks.
MACHINE AND BEAMLINES
ADAPTATION
End-of-beamline users require inter-bunch time which
can modified from the initial 30.45 MHz. Using a
technology composed of a 3.3 kV chopper in the injection
and a 60kV sinusoidal deflector in the experimental
beamlines, that is already in place, a new control system
on the chopper was devised. This system allows a “start-
stop” mode with a fixed number of bunches and various
settings for the inter-bunch time. Figure 5 shows the
results with 1282000 bunches on the end-of-beamline
intensity. Implementations include an EPICS
(Experimental physics and industrial control system)
software and PIC18 microcontrolers.
Figure 5: Intensity at the end of the beamline for the
“start-stop” pulsation system.
The cyclotron computing environment has as well
evolved. An EPICS system has been installed, initially
developed with Cosylab, first as a core to retrieve data
coming from the simantec S7 Siemens PLC of the
accelerator and second as the possible foundation for the
extension of the local network. Using a parallel CP-443
Ethernet card, it allows to access the accelerator data
without impacting the main control system provided by
IBA.
This network (Fig. 6) is foreseen to be the base for
several beam diagnostics and technical environment
measurements (eg water, gaz). An EPICS software,
developed by Ithemba, for Beam Loss monitors is also
being tested to later help the extension of beam
diagnostics on beamlines and the cyclotron vault.
Additionally, various upgrades are being performed on
the beamlines, the irradiation stations, and the cyclotron
environments (eg collimators, water cooling).
Figure 6: The intermediary planned phase for the
computing environment of the cyclotron.
CONCLUSION
The use of the C70 arronax has increased over the
years and several operational investigations are being
carried out through magnet settings studies. Also a first
emittance measurement with collimators at high intensity
is being addressed with a model dependant methodology.
Operation requirements have lead the need to develop a
pulsation system that will extend to a pulsed train system
in the injection and also, being part of a long term plan,
the computing environment of Arronax is broadening
through installation of new EPICS control systems.
ACKNOWLEDGMENT
This work has been, in part, supported by a grant from
the French National Agency for Research called
"Investissements d'Avenir", Equipex Arronax-Plus
noANR-11-EQPX-0004 and Labex IRON noANR-11-
LABX-18-01.
One of the authors, F.Poirier, acknowledges the work
of the students A.Letaeron and A.Sengar respectively on
the particle pulsation and first emittance measurements.
REFERENCES
[1] F. Haddad et al., “Arronax, a high-energy and high-
intensity cyclotron for nuclear medicine”, Eur J Nucl
Med Mol Imaging. 2008, 35, 1377-1387.
[2] F. Poirier et al., “The C70 ARRONAX in the hands-
on phase”, IPAC12, May 2012, MOPPD024.
[3] F. Poirier et al., “The C70 ARRONAX and Beamline
Status”, IPAC11, Sept. 2011, WEPS069.
[4] C. Duchemin, “Étude de voies alternatives pour la
production de radionucléides innovants pour les
applications médicales”, Ph.D. thesis, Subatech, 2015.
[5] M.G. Minty, F.Zimmermann, “Measurement and
control of Charged Particle Beams”, p.103, Springer,
2003.
[6] T.J. Roberts et al., “G4beamline Simulation Program
for Matter dominated Beamlines”, EPAC08, June
2008, WEPP120.

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Studies and Upgrades on the C70 Cyclotron at Arronax

  • 1. STUDIES AND UPGRADES ON THE C70 CYCLOTRON ARRONAX F. Poirier, S. Girault, Arronax, Saint-Herblain, and CNRS – DR17, Rennes France F.Bulteau Harel, J.B. Etienne, X.Goiziou, F. Gomez, A.Herbert, L.Lamouric, D. Poyac, H.Trichet, Arronax, Saint-Herblain, France C. Huet, Arronax, Saint-Herblain, and EMN, Nantes, France E. Mace, Arronax, Saint-Herblain, and INSERM, Nantes, France Abstract The multi-particle cyclotron C70 Arronax is fully running since 2010 and its RF run time has increased up to 4400 hours in 2015. The accelerator is used for a wide variety of experiments (physics cross-sections, radiolysis, radiobiology) and radio-isotope productions. This requires runs with 7 orders of intensity range from a few pA up to 350 A and a large range of particles energy. Machine and beamline studies are continuously needed. For example magnet intensity scan inside the cyclotron and in the beamlines, respectively with compensation coils and the quadrupoles have been done. These scans caracterise performances of the machine and help both operations and mitigation of particle losses. Additionally beam loss monitors and control systems are being devised to support further the high intensity and precision requirements on the runs. Also a pulsed train alpha beam system located in the injection has been designed. The proof of principle with a dedicated run has been performed. The results of the machine studies and status of these developments are presented in this paper. INTRODUCTION The cyclotron Arronax [1] (Accelerator for Research in Radiochemistry and Oncology at Nantes Atlantique), running since 2010, the year of its commissioning, has started in 2011 its hands-on phase [2]. Arronax has gradually increased the number of hours it uses the cyclotron. The cyclotron delivers beams separately in six vaults surrounding the main cyclotron vault [3]. Five of the vaults are used for high intensity beams and the sixth one, beamline for experiments, is dedicated to low and ultra- low intensity (<100 electric pA). The priority list for production of radio-isotopes covers both isotopes for imaging and therapy. It includes, but not exclusively, 82 Sr, 64 Cu, 211 At and 166 Ho. 211 At requires an energy degrader that has been installed in one of the beamline and as for 166 Ho, a neutronic activator is in use, all at intensities above 10A. RANGE OF OPERATION The cyclotron provides four types of positively charged particles (proton, alpha, deuterons, HH+) which intensity and energy can be modified according to the experimental needs. Figure 1 shows a map of the operation range for each particle at intensity from a few nA up to 100s of A on the target with energies from 32 MeV up to 70.3 MeV for protons. Protons and deuterons have the widest energy range mainly due to cross-section measurements being performed at Arronax on numerous physics production channels [4]. Several runs with protons for 82 SR production have started in 2016 at 150A on target, extending the production capacities at Arronax. Figure 1: The operation range for the C70 Arronax with the 4 particles in use. THE MACHINE OPERATION The use of the cyclotron, here expressed in term of number of RF hours, has increased over the years up to 4400h in 2015 as shown in Fig.2, being limited mostly by manpower. Each year includes 4 main preventive maintenances that are performed over a week. Also, a Computerized Maintenance Management System (CMMS) – MaintiMedia from Tribofilm, is in place since 2015, to support the general maintenance follow-ups. Figure 2: RF accumulated time per year since 2011 and as of august for 2016 and estimation for this year. The settings on the machine parameters at the beginning of a run are systematically adjusted to increase
  • 2. the transmission rate and as the operation last and magnets elements temperature increase, parameters such as main coils are optimised. In the case of new beam parameters e.g. new particle energy and/or intensity, being developed, systematic studies are planned. The studies include transmission rate and also scans with various settings on the machine as shown later. Table 1: Transmission Rate for the 3 Main Particles Particles Estimated Intensity in cyclotron [A] Transmission rate (End-of_line/injection) H+ 252 43% D+ 64 37% He2+ 26.6 10% The transmission rate from the faraday in the injection to the end-of-line is indicated in the table 1. The particles losses are mainly in the injection and below 2 MeV. Additional losses are along the trajectory in the cyclotron (neutral particles at the level of 4.4% for protons) and along the beamlines (a few percentage). MACHINE OPERATION STUDIES The cyclotron is constituted of several internal magnets beside the main coil which provide the average magnetic field for the valley and hills. These are 3 compensation coils at 3 different radius (internal, medium and external) and paired harmonic coils. While in a dual-beamline run, the compensation ones are adjusted such that maximum current is obtained at both exit and the harmonic ones are set such that symmetry in intensity is observed. A scan of the intensity on faraday cups at the extraction exit was performed as a function of the compensation coils. The result is plotted in Fig. 3 for the intensity as a function of the external and medium coil and shows a region of maximum transmission with a large stability area (red). It also indicates some region to be avoided as a discontinuity on the magnet elements is present when passing 0A. This type of scan did show the need to perform regular check with newly constructed sets of magnet taking into account several multi-scan results. This type of scan with the help of dedicated beamline diagnostics can be used to track the status of the beam (eg resonances in the machine leading to beam blow-up, and modification of the beam shape) and stabilises overall runs. Taking into account these scans will have to be mitigated with the modification of the particles final kinetic energy. BEAMLINE OPERATION STUDIES Emittance measurements are important for check of the stability of the machine, determining focusing spots on the target and losses in the beamlines. This is addressed first though quadrupole scans in the beamlines. Figure 3: Total extracted intensity [uA] on both-side faraday cup as a function of compensation coils medium and external settings. Quadrupole scan have been performed at intensities between 10 up to 30 A. These scans have the goal to find the best setting for transmission rate in the beamline, for adequate beam size at the target location, emittance measurements studies and potential use in ballistic beam- based alignment to optimise the trajectory of the beam inside the beamline. Figure 4: Quadrupole scan result with the 2 last consecutive magnets in the beamline. The coloring represents the interpreted intensity level on the collimators in the horizontal plane and the black dots the actual data points. The scan of Fig. 4, was first obtained to select data that could be used to perform first preliminary emittance measurements. The criteria being two-fold: centered position of the beam and a full shape containing a deep in the scan. The chosen scan are indicated in Fig. 4. The technique uses first a transformation of the signal on the 10 mm aperture radius collimator into beam dimension. The fitted beam size is plotted as a function of strength in the quadrupole setting. The parabola obtained is then fitted to acquire the emittance according to: �� = √�� �2⁄
  • 3. Where A and C are parameters of the fitting parabola [5] similar to single-wire scan and d is, a distance, here a fixed conversion factor from the simulation model in use. The technique is at the present time being tested for robustness. It relies on simulations model with G4Beamline [6] for the transformation of the signal on the collimator to a beam size. The first measurements indicated variation in the emittance by a factor of 4 for runs separated by a few weeks. MACHINE AND BEAMLINES ADAPTATION End-of-beamline users require inter-bunch time which can modified from the initial 30.45 MHz. Using a technology composed of a 3.3 kV chopper in the injection and a 60kV sinusoidal deflector in the experimental beamlines, that is already in place, a new control system on the chopper was devised. This system allows a “start- stop” mode with a fixed number of bunches and various settings for the inter-bunch time. Figure 5 shows the results with 1282000 bunches on the end-of-beamline intensity. Implementations include an EPICS (Experimental physics and industrial control system) software and PIC18 microcontrolers. Figure 5: Intensity at the end of the beamline for the “start-stop” pulsation system. The cyclotron computing environment has as well evolved. An EPICS system has been installed, initially developed with Cosylab, first as a core to retrieve data coming from the simantec S7 Siemens PLC of the accelerator and second as the possible foundation for the extension of the local network. Using a parallel CP-443 Ethernet card, it allows to access the accelerator data without impacting the main control system provided by IBA. This network (Fig. 6) is foreseen to be the base for several beam diagnostics and technical environment measurements (eg water, gaz). An EPICS software, developed by Ithemba, for Beam Loss monitors is also being tested to later help the extension of beam diagnostics on beamlines and the cyclotron vault. Additionally, various upgrades are being performed on the beamlines, the irradiation stations, and the cyclotron environments (eg collimators, water cooling). Figure 6: The intermediary planned phase for the computing environment of the cyclotron. CONCLUSION The use of the C70 arronax has increased over the years and several operational investigations are being carried out through magnet settings studies. Also a first emittance measurement with collimators at high intensity is being addressed with a model dependant methodology. Operation requirements have lead the need to develop a pulsation system that will extend to a pulsed train system in the injection and also, being part of a long term plan, the computing environment of Arronax is broadening through installation of new EPICS control systems. ACKNOWLEDGMENT This work has been, in part, supported by a grant from the French National Agency for Research called "Investissements d'Avenir", Equipex Arronax-Plus noANR-11-EQPX-0004 and Labex IRON noANR-11- LABX-18-01. One of the authors, F.Poirier, acknowledges the work of the students A.Letaeron and A.Sengar respectively on the particle pulsation and first emittance measurements. REFERENCES [1] F. Haddad et al., “Arronax, a high-energy and high- intensity cyclotron for nuclear medicine”, Eur J Nucl Med Mol Imaging. 2008, 35, 1377-1387. [2] F. Poirier et al., “The C70 ARRONAX in the hands- on phase”, IPAC12, May 2012, MOPPD024. [3] F. Poirier et al., “The C70 ARRONAX and Beamline Status”, IPAC11, Sept. 2011, WEPS069. [4] C. Duchemin, “Étude de voies alternatives pour la production de radionucléides innovants pour les applications médicales”, Ph.D. thesis, Subatech, 2015. [5] M.G. Minty, F.Zimmermann, “Measurement and control of Charged Particle Beams”, p.103, Springer, 2003. [6] T.J. Roberts et al., “G4beamline Simulation Program for Matter dominated Beamlines”, EPAC08, June 2008, WEPP120.