Tokyo Chemical Industry (TCI) is your reliable partner for specialty chemicals in the area of Chemical Synthesis, Materials Science, Life Science and Analytical Chemistry for laboratories and industries research. Also, fine chemicals such compounds for photovoltaic applications, as battery raw materials, and glycol building blocks are our strength. Learn about our Featured Products, TCI Practical Examples, Chemical Packaging and Delivery.
2. TABLE OF CONTENTS
03
08
About TCI Products
05
Featured Products
03
Company Profile & Mission
04
Product Highlights
10
TCI’s Practical Examples
11
Packaging and Containers
18
13
14
15
17
TCI’s Technical Strength
TCI Product Spotlight
Professor’s Corner
20
Locations
Exhibitions & Conferences
Campaigns/Offers/Schemes
02
3. 02
03
Company Profile & Mission
Tokyo Chemical Industry Co., Ltd. (TCI) is a leading worldwide manufacturer of specialty organic
chemicals founded in 1946. TCI provides organic laboratory chemicals as well as pharmaceutical,
cosmetic and functional materials. More than 70 years of synthesis experience and multi-purpose
plants enable TCI to offer more than 30,000 products as well as custom synthesis. TCI established
overseas facilities in North America, Europe, China and India to serve customers worldwide. Our
aim is always to provide a growing and valuable range of research products and to reach higher
levels of quality and customer service. Our symbol, designed when TCI was first established,
depicts the structure of anthracene, a representative image of organic chemistry.
TCI India is committed to providing outstanding customer service and high quality reagents in a
timely manner.
We are global technical experts serving society to
enrich people's lives by contributing to the advancement of science.
We meet the needs of research fields in a timely manner
by discovering and providing a wide variety of chemical
reagents that no one else can provide.
That is our most important mission.
Company Profile
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TCI Mission
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4. Keeping your analytical chemistry error free originates with TCI’s high
purity reagents. We assist you in choosing the right reagents while
managing your time and budget. Using TCI’s analytical reagents,
measured results become more reliable and robust. Maximize the
desired signal and minimize noise with TCI’s end-to-end, high quality analytical reagents.
The use of versatile intermediates is important for oligosaccharide
syntheses as is the choice for suitable protective and de-protective
groups that can hold up against a variety of reaction conditions.
To ensure the desired reaction is reached, TCI offers a variety of
reagents and enzymes for your research.
04
About TCI Products
About Our Products
...........................................................................................................................
TCI is committed to meeting your expectations by providing the highest quality, most reliable
organic reagents in the fields of Synthetic Chemistry, Life Science, Materials Science, Analytical
Science, and more. Our specialty organic and inorganic chemicals are recognized as best-in-class
by top research labs, universities and manufacturers. We strive to have the highest product
availability on the market and with strategically placed warehouses, count on TCI having the
research chemicals in-stock and ready to ship when you need them.
At TCI, we manufacture market leading synthetic reagents for
transformations such as coupling, carbon to carbon bond formation,
building blocks, protection chemistry and catalysis. Offering a
broad range of synthetic reagents, you can rely on TCI for all of
your synthetic reagent needs.
Chemistry
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Advances in material science has led to the creation of new
and innovative products found in virtually every aspect of today's
high-tech world. Global manufactures rely on TCI's high purity
reagents to make personal devices faster, materials lighter and
stronger, energy cleaner while advancing research to new levels.
Material Science
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The life science field demands skilled scientists, modern equipment
and high purity reagents that produce repeatability. Employing
advanced synthesis, refinement, and analysis techniques, TCI offers
numerous world-class life science reagents including chromogenic
enzyme substrates, biochemical substances, antioxidants and more.
Life Science
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Glycoscience
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Analytical Chemistry
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5. 05
TCI’s Featured Products
Covalent Organic Frameworks (COFs) Linkers
...........................................................................................................................
Covalent organic frameworks (COFs) are crystalline organic frameworks consisting of a network
structure made of covalent bonds. COFs are classified as porous crystalline materials similar to
metal-organic frameworks (MOFs)/porous coordination polymers (PCPs) and zeolites. They include
2D COFs, which are constructed by stacking layers of 2D covalently bonded sheets, and 3D COFs,
which are constructed by 3D connected frameworks. COFs are expected to be used as molecular
storage or separation materials, catalysts, electronic materials, energy storage materials, battery
materials, and drug delivery materials, due to their porosity, crystallinity, and structural diversity.
COFs are designed and synthesized by combining monomers, also called linkers, according to
intended topology. TCI has more than 70 linkers in stock, and we are constantly adding new items
to our catalog. Common linkers are shown below by functional groups.
[T2947] [T0010]
[T3688] [P0170]
6. 06
TCI’s Featured Products
Palladium Complex Catalyzing the Suzuki-Miyaura Coupling Reactions
of Heteroaryl Chlorides
...........................................................................................................................
Graphitic Carbon Nitride (g-C3
N4
) Related Reagents
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The Pd(Amphos)2
Cl2
[Product No. B6255] is an air-stable divalent palladium(II) complex that
efficiently catalyzes Suzuki-Miyaura coupling reaction. The reaction is applicable to substrates with
heteroatom containing groups (such as heteroaryl chlorides, thiol, amino, alkoxy amino and alkoxy
groups) which can be catalyst poisons. In addition, the complex exhibits higher turnover
numbers (TONs).
Advantages:
• Air-stable powder
• Highly active for the cross-coupling of heteroaryl chlorides as reaction substrates
Graphitic carbon nitride (g-C3
N4
) [G0539] is a promising metal-free photocatalyst, and is useful to
compare its physical properties. Melamine monomer [T0337] and melem [M3538] can be used as
the synthetic raw materials and the partial substructures of g-C3
N4
. Please use high purity melamine
monomer and melem for the precision synthesis of g-C3
N4
.
7. 07
TCI’s Featured Products
Cubane-Containing Building Blocks: The Bioisostere of Benzene Ring
...........................................................................................................................
Regenerative Medicine Related Reagents
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In the field of drug design, cubane is considered to be the bioisostere of benzene due to its
diagonal distance of the skeleton being almost the same as the diameter of benzene. The strategy
to introduce the cubane skeleton instead of the benzene ring has gathered much interest in recent
drug discovery. This is expected to improve solubility and pharmacokinetics by breaking the
planarity of the entire molecule. TCI offers a series of cubane compounds with various functional
groups [Product No. D5542, M3466, M3505, C3810, C3808, B6415] useful for derivatization, and
also can provide custom synthesis of various derivatives related to these compounds.
The term regenerative medicine refers to a next-generational field of medical techniques in which
cells are taken from patients, cultured, expanded, and returned to the patient in some manner in
order to regenerate tissues or promote wound healing. The type of stem cell perhaps most
frequently employed in these applications are known as induced pluripotent stem cells (iPSCs).
In recent years, organoids have come to the forefront as a model for the application of human
iPSCs in regenerative medicine. Organoids are in-vitro 3D cultured cell aggregates derivable from
both iPSCs as well as somatic stem cells which are not only capable of self-organization and long
term self-renewal, but which also exhibit similar morphology and function to the tissues from which
they were derived. This is achieved through the use of physical and biochemical cues, such as
extracellular matrix components and niche factors, which are able to recapitulate cells' natural
environment within living tissue.
Here at TCI, we have an extensive lineup of chemicals frequently used in both organoid culture
and iPS generation / differentiation.
8. 08
DOTA Derivatives as Chelating Agents for Radioisotopes
.............................................................................................................
A Thioamide for the Potent Inhibition of TGF-β Signaling
...........................................................................................................................
A 83-01 [Product No. A3324] is a thioamide which acts as a
potent inhibitor of the TGF-β type I receptor superfamily
activin-like kinases Activin-Like Kinase 4 (ALK4), 5 (ALK5), and
7 (ALK7), making it specific for the TGF-β/Activin A/Nodal
branch of the TGF-β signaling pathway. Inhibition with A 83-01
prevents phosphorylation of Smad2/3, which in turn leads to
attenuation of TGF-β-mediated growth inhibition and
epithelial-to-mesenchymal transition. A 83-01 is a common
component of organoid culture media; where it is used in
concert with other niche factors to promote self-differentiation
and self-assembly of stem cells into functionalized structures
resembling native structures in vivo.
Product Highlights
DOTA (1,4,7,10-tetraazacyclodecane-1,4,7,10-tetraacetic acid) is a chelating agent which consists
of a 12-membered ring containing nitrogen and can coordinate with various metal species. DOTA
is widely used in PET (Positron Emission Tomography) and MRI (Magnetic Resonance Imaging)
scans due to the high stability of its coordination compounds. Several DOTA derivatives are
available such as azido-mono-amide-DOTA [Product No. A3478] with an azido group,
DOTA-ADIBO [Product No. D6006] with an ADIBO group, and DOTA-NHS hexafluorophosphate
trifluoroacetate [Product No. D6007] with an NHS group, allowing for quick and easy labeling of
various probes. Examples in the literature include: The DOTA labeling of trastuzumab with and the
subsequent coordination of the radioisotope 67
Ga allowed researchers to examine the dynamics
of trastuzumab in a rat model. Additionally, the DOTA labeling of polyamido-amine (PAMAM) with
and the subsequent coordination of the radioisotope 68
Ga have been an effective strategy to
study the localization of PAMAM in a mouse model since PAMAM is believed to be effective in
transporting drugs throughout the body.
[A3478]
Azido-mono-amide-DOTA
[D6006]
DOTA-ADIBO
[D6007]
DOTA-NHS Hexafluorophosphate
Trifluoroacetate
[A3324]
A 83-01
9. Iithiation
09
Electrophilic Sulfur Introducing Reagent
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Product Highlights
Mediator for Organic Electrochemical Reactions
...........................................................................................................................
Recently, organic electrochemical reactions have attracted much attention due to their high
functional group tolerance and high energy efficiency, and have been applied to the total
synthesis of natural products. TCNHPI [Product No. H1765] is utilized as a mediator in organic
electrochemical reactions. So far, the scalable allylic C-H bond oxidation of terpenes such as
valencene and steroids using TCNHPI as a mediator have been reported.
Bis(phenylsulfonyl) sulfide [Product No. B3288] enables the construction of thiophene rings or
sulfide bonds in rigid units by the reacting with a variety of nucleophiles such as aryl lithium under
mild conditions. It is therefore a useful reagent and a synthetic equivalent of sulfur dichloride (SCl2
),
which is highly toxic and difficult to handle. In addition, benzenesulfinic acid, a by-product of the
reaction, is soluble in water and can be easily removed by liquid separation. It has been reported
that the thienoacenes synthesized by using bis(phenylsulfonyl) sulfide are used as OFET materials.
Valencene
tBuOOH
10 mA/mmol
TCNHPI (cat.)
pyridine
LiCIO4
TCNHPI
acetone
Reference: M. Yan, Y. Kawamata, P. S. Baran, Chem. Rev. 2017, 117, 13230.
Reference: L. Li, C. Zhao, H. Wang, Chem. Rec. 2016, 16, 797.
[B3288]
Bis(phenylsulfonyl) Sulfide
10. 10
Chemoselective Reduction of Nitro Group Using Diboronic Acid
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TCI’s Practical Examples
The Deoxyfluorination of Alcohol Using a Photoredox Catalyst
...........................................................................................................................
In TCI Practical Examples, we introduce examples of reactions carried out by our synthesis staff,
along with analysis data. Product Highlights focuses on specific products among our product line,
introducing the products' characteristics and means of use.
cat. 4,4 -bipyridyl
DMF
Y. 91%
Diboronic Acid
rt
€
‚
We are proud to present the selective reduction of nitro groups from trans-4-nitrostilbene to
trans-4-aminostilbene using diboronic acid [Product No. T2953] and 4,4'-bipyridyl.
We are proud to present the deoxyfluorination of 2-methyl-4-phenyl-2-butanol with F-TEDA-BF4
in the presence of [Ir(p-F(Me)ppy)2
-(4,4'-dtbbpy)]PF6
[Product No. B6258], a photoredox iridium
catalyst. The tertiary alcohol activated as an oxalate half-ester is utilized as an efficient radical
precursor to conduct C-F coupling.
11. 11
Packaging and Containers
Packaging and Containers
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These are the types of containers used for packaging our products. Appropriate types of containers
are selected for each product according to the application and characteristics.
Dual Seal Bottled Reagents from TCI
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TCI introduced the newly developed double cap system, the DualSeal for moisture and
oxygen-sensitive liquid chemicals, allowing to keep them in good condition until the last drop.
TCI offers many DualSeal bottled products like Volatile Solutions, Metallic Salt Solutions,
Dehydrated Solvents Organometallic Reagents. TCI is constantly adding more and more
sensitive products to this range.
Plastic Bottles
Glass Bottles
Vials
Ampules
PFA Bottles
Plastic Bottles with Glass Insert
Glass Bottles with Plastic Insert
Pressurized Cylinders
12. 12
Packaging and Containers
What is DualSeal?
Features of DualSeal
Air-sensitive reagents can be safely dispensed without exposure to air.
Even after piercing the septum cap, the PTFE sheet on the blue cover cap provides sealing
protection.
Easy to dispose of caps and bottles separately.
All products using DualSeal have a note in the Packaging and Container section on our Product
Details page.
Here's an animated video we created for
introducing the newly developed double cap
system, the DualSeal. Please visit our website or
our YouTube channel to view the video.
How to identify DualSeal packaging before placing an order
Animated Video on DualSeal Bottled Reagents
DualSeal consists of two parts; the blue
outer cap and the white septum cap both of
which can be screwed on and off.
No additional sealing is required after
piercing the septum cap with a needle. Just
screw the outer-cap back in place.
Ref: https://www.tcichemicals.com/IN/en/TCI-Product-Videos
13. 13
We have over 300 equipment units of 100 types. TCI offers equipment and technology to
guarantee high standards of quality.
TCI’s Technical Strength: Apparatus
TCI Manufacturing equipment :
...........................................................................................................................
Glass-lined reaction vessels: 120 units approximately.
•
Distillation Apparatus: Refining technology is vital for achieving high levels of purification.
•
Autoclave: Manufacturing of products that can only be compounded using high-pressure
reaction technology.
•
14. 14
TCI Product Spotlight
CAS RN: 20816-12-0 | Product Number: O0308 | Product Name: Osmium Tetroxide (4% in
Water)
More Info : https://www.tcichemicals.com/IN/en/p/O0308
CAS RN: 107-21-1 | Product Number: E0105 | Product Name: Ethylene Glycol
https://www.tcichemicals.com/IN/en/p/E0105
CAS RN: 302-17-0 | Product Number: C0073 | Product Name: Chloral Hydrate
More Info : https://www.tcichemicals.com/IN/en/p/C0073
CAS RN: 10022-70-5 | Product Number: S0939 | Product Name: Sodium Hypochlorite
Pentahydrate
More Info : https://www.tcichemicals.com/IN/en/p/S0939
CAS RN: 75-29-6 | Product Number: C0267 | Product Name: 2-Chloropropane
https://www.tcichemicals.com/IN/en/p/C0267
Used as an alkylating agent in organic synthesis.
Used as a building block in organic synthesis.
Applications:
Applications:
Applications:
More Info :
Applications:
More Info :
Applications:
...........................................................................................................................
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Sodium Hypochlorite Pentahydrate is a useful reagent for
preparation of aldehydes and ketones by oxidation of primary
and secondary alcohols.
Ethylene glycol is useful for various applications in synthetic
chemistry (as a reagent in cyclocondensation reactions with
aldehydes and ketones to form 1,3-dioxolanes) etc. and
general purpose (used as an ingredient in hydraulic fluids,
printing inks, and paint solvents) as well.
Versatile precursor material and reagent for the synthesis
of composites of graphene oxide, carbon nanotubes, and
molybdeum compounds.
OsO4
(4wt% in H2
O) is widely employed in organic synthesis
especially for hydroxylation reactions. Additionally, it is also
involved in the oxidative cleavage of alkenes.
CAS RN: 51429-74-4 | Product Number: P1910 | Product Name: Phosphomolybdic Acid
Hydrate
https://www.tcichemicals.com/IN/en/p/P1910
More Info :
Applications:
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15. 15
Professor’s Corner
Dr. Rambabu Chegondi has been selected for the prestigious SERB-Science and Technology
Award for Research (SERB-STAR) Award, 2022. This award is instituted by the SERB,
Government of India to recognize and reward outstanding performance of Principal
Investigators (PIs) of individual-centric SERB Projects with an “Excellent” grade.
Dr. Rambabu Chegondi was chosen for the award by SERB-STAR Award Selection Committee
among the selected 18 Awardees in different disciplines all over the nation based upon
outcome of completed project, his overall research accomplishments and quality of publications
among eligible nominations.
Dr. Rambabu Chegondi gladly acknowledges TCI Chemicals as the preferred chemical supplier
for his research owing to the quality assurance and wide range of products available.
TCI Chemicals products, ranging from catalysts, fine chemicals to building blocks
chemicals and reagents has always been one of the important part of the chemical inventory
for Dr. Rambabu’s research group.
Dr. Rambabu Chegondi, FRSC received his M.Sc. degree from University of Hyderabad and
completed Ph.D. in Organic Chemistry from CSIR-IICT, Hyderabad. Later, he went to The
University of Kansas, USA for postdoctoral studies. After returning from USA, he joined CSIR-IICT,
Hyderabad as a Scientist.
Dr. Rambabu has published more than 50 research publications in peer-reviewed international
journals of high impact. Recently, he was awarded Dr. A V Rama Rao Young Scientist Award for the
year 2019 and Thieme Chemistry Journals Award 2023. Currently, he is also an Editorial Board
Member of “Organic Letters” a leading American Chemical Society Journal.
Dr. Rambabu Chegondi, FRSC, Principal Scientist from
CSIR-Indian Institute of Chemical Technology (CSIR-IICT),
Hyderabad.
16. 16
Dr. Maddi Sridhar Reddy has been selected for the prestigious SERB-Science and
Technology Award for Research (SERB-STAR) Award, 2022. This award is instituted by the
SERB, Government of India to recognize and reward outstanding performance of
Principal Investigators (PIs) of individual-centric SERB Projects with an “Excellent” grade.
Dr. Maddi Sridhar Reddy was chosen for the award by SERB-STAR Award Selection
Committee among the selected 18 Awardees in different disciplines all over the nation based upon
outcome of completed project, his overall research accomplishments and quality of
publications among eligible nominations. The support includes a fellowship of Rs. 15,000/- per
month, a research grant of Rs. 10 lakhs per annum, and Rs.1 lakh per annum as overhead charges
for a period of three years.
Dr. Sridhar Reddy, received his M.Sc. degree from Osmania University and completed his
Ph.D. in Organic Chemistry from CSIR-IICT, Hyderabad. Later, he went to The University of
Sherbrooke, Canada for postdoctoral studies. After returning from Canada, he joined CSIR-CDRI,
Lucknow as a Senior Scientist and later on moved to CSIR-IICT in 2017. Dr. Sridhar Reddy
published more than 70 research publications in peer-reviewed international journals of high
impact. For his endeavors, he received the prestigious Thieme Young Scientist Award for the year
2015, CDRI incentive Award for the year 2016, AVRA Young Scientist Award for the year 2017 along
with SERB-STAR award for the year 2022.
He has used several metal-based catalysts purchased from TCI for executing
many of his projects related to this award. Some bioactive molecules used for late stage
functionalizations were also purchased from TCI.
He appreciates the prompt response by TCI, helped him get through his projects on time and in a
successful manner.
Dr. Maddi Sridhar Reddy, Senior Principal Scientist from
CSIR-Indian Institute of Chemical Technology (CSIR-IICT),
Hyderabad.
Professor’s Corner
17. 17
Exhibitions Conferences
We participated in the following exhibitions and conferences.
Chem Expo India – April 2023
...........................................................................................................................
Apr 18-19, 2023
Venue: Hall 1, Stall No - E36,
Bombay Exhibition Centre,
Mumbai, Maharastra.
CSIR-AMPRI One Week One Lab Program - May 2023
...........................................................................................................................
May 14-18, 2023
Venue: CSIR – Advanced Materials and Processes
Research Institute (AMPRI), Bhopal.
Bhopal, Madhya Pradesh.
CSIR-CSMCRI One Week One Lab Program - April 2023
...........................................................................................................................
Apr 10-14, 2023
Venue: CSIR – Central Salt and Marine Chemicals
Research Institute (CSMCRI),
Bhavnagar, Gujarat.
18. Campaigns/Offers/Schemes
TCI’s Welcome Offer for New Professors :
...........................................................................................................................
Welcome offers are a great way to let our customers save money. As the name of the scheme
suggests, new professors will get a 5% worth free goods coupon on every purchase of
TCI products.
Eligibility Criteria:
Professors who joined on Jan 2021 or later are eligible to avail this scheme.
To know more about the scheme, please contact our Sales associates or our Authorized
distributors NOW!
This offer is valid for ONE YEAR.
Schemes
Referral Scheme Program :
...........................................................................................................................
Let us reward you for referring a new customer to TCI. Here’s how it works:
Terms Conditions:
You can refer new start-ups of your friends or Ex- Colleagues to TCI anytime and from
anywhere through the below referral form.
You have a chance to win attractive gifts once your lead starts ordering TCI products.
Your lead should order chemicals from TCI – we require a minimum order value of INR 5000.
Order needs to be received within 1 Month of reference.
This Referral Scheme is valid for only New Startup firms(Only Corporates). We consider a user
as a New Start-up if their GST Registration is dated 1 Jan 2021 or later.
The decision of TCI will be final to decide the eligibility of the referral for gift.
18
19. 19
Schemes
New Lab Set-Up Program :
...........................................................................................................................
Starting a new lab involves planning and making key financial decisions. We at TCI understand
your situation. We have created the New Lab Set-up Scheme to help you grow and achieve
your business objectives. We support the new labs with great discounts at a early stage of
starting your business.
Eligibility:
New Lab Set-up Scheme Benefits:
Firms having laboratories for using Chemicals and have registered or incorporated their firms
in 2021 or later will be eligible to avail this scheme.
Significant savings on TCI’s entire range of 30K + Products for 1 Year from the date of 1st
Order.
Orders will be processed and dispatched within 24 Hours from Hyderabad warehouse.
Direct single Point of contact for assistance and responses to your queries.
Automated shipment notifications with a Docket number to track shipments.
Distributors Information
Our Distributors :
...........................................................................................................................
TCI has distributors all over India.
Find our distributors - https://www.tcichemicals.com/IN/en/distributor/index
For more information or to avail our Offers Schemes, please contact our sales associates.
Talk To Our Experts :
S.No Zone State Email-ID Contact Number
1 Pan India Telangana and Andhra Pradesh anil.kumar@tcichemicals.com 7397725901
2 South Karnataka vignesh.cm@tcichemicals.com 7386660359
3 South Telangana, Odisha and Chhattisgarh asif.ali@tcichemicals.com 7397725903
4 South Tamil Nadu, Kerala and Andhra Pradesh dineshkumar.b@tcichemicals.com 9677011321
5 West Maharashtra and Madhya Pradesh manoj.tripathi@tcichemicals.com 7397725904
6 Mr. Rahul Thakar West Gujarat rahul.a@tcichemicals.com 7976470839
7 West Goa and Maharashtra satish.kale@tcichemicals.com 9004592071
8 North Delhi, Haryana, Jammu Kashmir, Rajasthan govind.sharma@tcichemicals.com 7397725906
9 North
Madhya Pradesh(Bhopal, Jhansi , Gwalior), Uttar
Pradesh, Uttarakhand and Delhi.
jagdish.kumar@tcichemicals.com 7397725907
10 Mr. Vipan North Chandigarh, Punjab and Himachal Pradesh vipan.thakur@tcichemicals.com 9789861222
11 North / East
West Bengal, Bihar, Jharkhand, Assam, Sikkim and
East/North East
ankitmitra.t@tcichemicals.com 7397725908
TCI Zone Wise Contact Persons
Name
Mr. Anil Kumar
Mr. Vignesh C.M.
Mr. Jagdish Kumar
Mr. Ankit Mitra
Mr. Mohamed Asif Ali
Mr. Dinesh Kumar
Mr. Manoj Tripathi
Mr. Satish Kale
Mr. Govind Kumar Sharma