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The circulatory system transports blood, nutrients, gases, hormones, and wastes throughout the body. It consists of the heart, blood vessels (arteries, veins, and capillaries), and blood. The heart pumps blood through two circuits - the pulmonary circulation and the systemic circulation. It has four chambers and uses valves to ensure one-way blood flow. The cardiovascular system is regulated by both intrinsic and neural factors. Diseases can occur if the circulatory system is not functioning properly.
1. The document discusses the evaluation and treatment of COPD exacerbations in the emergency department. Common causes of exacerbation include viral and bacterial infections.
2. Initial treatment involves bronchodilators, steroids, oxygen supplementation, and antibiotics if pneumonia is present. Ventilation may be considered for severe exacerbations.
3. Upon discharge, the focus shifts to optimizing inhaler therapy and assessing eligibility for pulmonary rehabilitation to reduce readmissions.
Enteral and parenteral nutrition are important for critically ill children to prevent further deterioration. Enteral nutrition is preferred when possible due to gut trophic effects. Nutritional requirements vary based on factors like age, illness severity, and metabolic stress. Careful monitoring is needed to avoid overfeeding and associated complications while meeting caloric and protein goals tailored for each patient.
Diagnosis and management of central line infectionsDr. Armaan Singh
The document discusses the diagnosis and management of catheter-related bloodstream infections, noting that differential time to positivity on blood cultures can diagnose CRBSI and certain organisms or clinical scenarios require catheter removal. It provides guidance on empiric antibiotic selection based on patient risk factors and outlines appropriate treatment duration.
This document summarizes the respiratory system. It begins with an introduction and then discusses the developmental anatomy, functions including ventilation and gas exchange, and regulation of respiration through neural control centers in the brainstem. It also covers applied topics like effects of altitude and diving. The respiratory system works to oxygenate tissues and remove carbon dioxide through four main functions: ventilation, gas diffusion, transport, and regulation. Respiration is regulated by chemoreceptors sensitive to oxygen and carbon dioxide levels, as well as pH levels, to maintain homeostasis.
Alcohol withdrawal symptoms and management are discussed. Symptoms include tachycardia, hypertension, fever, and agitation and occur 48 hours after last drink. The CIWA protocol monitors for withdrawal symptoms and manages with IV fluids, vitamins, and lorazepam prn. Electrolyte abnormalities should also be monitored and treated. Withdrawal risk is greatest 12-24 hours after last drink and complications like seizures or delirium tremens may require ICU care.
- Correction insulin is preferable to sliding scale insulin for managing inpatient hyperglycemia as it treats current high blood sugars and prevents future highs through the use of basal, nutritional, and correctional insulin components.
- The case study patient should be started on correctional insulin therapy which includes initiation of basal insulin, nutritional insulin with meals, and additional correctional insulin for blood sugars over target.
- When initiating or adjusting insulin therapy in the hospital, consideration should be given to the patient's diabetes type and weight to determine the total daily insulin dose and regimen. Frequent monitoring and adjustments are important to achieve good glycemic control.
Acute Coronary Syndrome (ACS) refers to a range of conditions caused by reduced blood flow in the coronary arteries. It includes Unstable Angina (UA), Non-ST-segment elevation myocardial infarction (NSTEMI), and ST-segment elevation myocardial infarction (STEMI). ACS is diagnosed based on electrocardiogram (ECG) findings and cardiac enzyme levels. STEMI shows ST elevations and enzyme elevations, while NSTEMI shows ST depressions/inversions and enzyme elevations without ST elevations. UA shows non-specific ECG changes and normal enzymes. Risk stratification systems like the TIMI score are used for NSTEMI/UA patients to guide management, which may
The circulatory system transports blood, nutrients, gases, hormones, and wastes throughout the body. It consists of the heart, blood vessels (arteries, veins, and capillaries), and blood. The heart pumps blood through two circuits - the pulmonary circulation and the systemic circulation. It has four chambers and uses valves to ensure one-way blood flow. The cardiovascular system is regulated by both intrinsic and neural factors. Diseases can occur if the circulatory system is not functioning properly.
1. The document discusses the evaluation and treatment of COPD exacerbations in the emergency department. Common causes of exacerbation include viral and bacterial infections.
2. Initial treatment involves bronchodilators, steroids, oxygen supplementation, and antibiotics if pneumonia is present. Ventilation may be considered for severe exacerbations.
3. Upon discharge, the focus shifts to optimizing inhaler therapy and assessing eligibility for pulmonary rehabilitation to reduce readmissions.
Enteral and parenteral nutrition are important for critically ill children to prevent further deterioration. Enteral nutrition is preferred when possible due to gut trophic effects. Nutritional requirements vary based on factors like age, illness severity, and metabolic stress. Careful monitoring is needed to avoid overfeeding and associated complications while meeting caloric and protein goals tailored for each patient.
Diagnosis and management of central line infectionsDr. Armaan Singh
The document discusses the diagnosis and management of catheter-related bloodstream infections, noting that differential time to positivity on blood cultures can diagnose CRBSI and certain organisms or clinical scenarios require catheter removal. It provides guidance on empiric antibiotic selection based on patient risk factors and outlines appropriate treatment duration.
This document summarizes the respiratory system. It begins with an introduction and then discusses the developmental anatomy, functions including ventilation and gas exchange, and regulation of respiration through neural control centers in the brainstem. It also covers applied topics like effects of altitude and diving. The respiratory system works to oxygenate tissues and remove carbon dioxide through four main functions: ventilation, gas diffusion, transport, and regulation. Respiration is regulated by chemoreceptors sensitive to oxygen and carbon dioxide levels, as well as pH levels, to maintain homeostasis.
Alcohol withdrawal symptoms and management are discussed. Symptoms include tachycardia, hypertension, fever, and agitation and occur 48 hours after last drink. The CIWA protocol monitors for withdrawal symptoms and manages with IV fluids, vitamins, and lorazepam prn. Electrolyte abnormalities should also be monitored and treated. Withdrawal risk is greatest 12-24 hours after last drink and complications like seizures or delirium tremens may require ICU care.
- Correction insulin is preferable to sliding scale insulin for managing inpatient hyperglycemia as it treats current high blood sugars and prevents future highs through the use of basal, nutritional, and correctional insulin components.
- The case study patient should be started on correctional insulin therapy which includes initiation of basal insulin, nutritional insulin with meals, and additional correctional insulin for blood sugars over target.
- When initiating or adjusting insulin therapy in the hospital, consideration should be given to the patient's diabetes type and weight to determine the total daily insulin dose and regimen. Frequent monitoring and adjustments are important to achieve good glycemic control.
Acute Coronary Syndrome (ACS) refers to a range of conditions caused by reduced blood flow in the coronary arteries. It includes Unstable Angina (UA), Non-ST-segment elevation myocardial infarction (NSTEMI), and ST-segment elevation myocardial infarction (STEMI). ACS is diagnosed based on electrocardiogram (ECG) findings and cardiac enzyme levels. STEMI shows ST elevations and enzyme elevations, while NSTEMI shows ST depressions/inversions and enzyme elevations without ST elevations. UA shows non-specific ECG changes and normal enzymes. Risk stratification systems like the TIMI score are used for NSTEMI/UA patients to guide management, which may
The document discusses the inpatient management of acute decompensated heart failure. Key points include identifying signs and symptoms of ADHF, obtaining pertinent labs and imaging to evaluate the patient, and treating with intravenous diuretics followed by chronic medications like ACE inhibitors, beta blockers, and spironolactone prior to discharge with close follow up.
This document discusses the management of constipation in adults. Constipation is defined using Rome III criteria as having two of the following: straining, lumpy hard stools, incomplete evacuation, use of digital maneuvers, or less than three bowel movements per week. Therapy includes lifestyle modifications like increased fluid/fiber intake and exercise, as well as laxatives such as stimulants, osmotics, and bulk formers. For the case presented, an appropriate treatment would be the osmotic laxative lactulose.
This document defines different types of pneumonia including community acquired pneumonia (CAP), hospital-acquired pneumonia (HAP), healthcare-associated pneumonia (HCAP), and ventilator-associated pneumonia (VAP). It describes common clinical features, diagnostic testing recommendations including chest radiographs, severity assessment scores, and treatment guidelines based on patient risk factors and pneumonia type. Initial treatment often includes broad-spectrum antibiotics while considering possible multidrug-resistant pathogens, with options to address a lack of improvement such as fungal infections or tuberculosis.
This document provides an overview and guidelines for choosing antibiotics. It discusses collecting cultures before starting antibiotics and ensuring appropriate dosing. Common antibiotics are reviewed including beta-lactams like penicillins, cephalosporins, and carbapenems as well as quinolones, macrolides, and metronidazole. Factors to consider for antibiotic selection include location and type of infection, patient history, and risk of drug-resistant pathogens. Quick guides are provided for coverage of pseudomonas, anaerobes, MRSA, and VRE.
This document discusses renal stone disease. It identifies common risk factors like male sex, obesity, and dietary factors. Typical symptoms include flank pain, nausea, and hematuria. The most common types of stones are calcium oxalate, calcium phosphate, and struvite. Non-contrast CT is the gold standard for imaging. Stones less than 5mm often pass spontaneously, while larger stones may require urologic intervention.
1. The new guidelines recommend initiating moderate or high-intensity statin therapy for patients in four categories based on their cardiovascular risk, rather than targeting a specific LDL-C level.
2. The four categories are: individuals with clinical atherosclerotic cardiovascular disease, LDL-C over 190 mg/dL, diabetes between ages 40-75 with LDL-C 70-189 mg/dL, and 10-year risk over 7.5% for ages 40-75 with LDL-C 70-189 mg/dL.
3. Lipids should be measured during follow-ups to assess adherence, not to achieve a specific target level.
This document discusses relative adrenal insufficiency, a condition where the adrenal glands do not adequately increase cortisol production during physiological stress such as sepsis. It defines relative adrenal insufficiency and explains that testing for it can be unreliable. For patients in sepsis who require vasopressors, the document recommends having a low threshold to treat with hydrocortisone but not fludrocortisone, as it has not been shown to help. The case presented is of a man in sepsis, and the recommended next step is to administer hydrocortisone.
The patient is a 20-year-old male with sickle cell disease who presents with several chronic and acute complications. He has a history of delayed puberty, joint pain, weakness and cough. Examination reveals decreased growth, severe anemia, leg ulcers, enlarged spleen and fever. Laboratory tests show hemoglobin of 8g/dL and reticulocyte count of 25%. The most probable cause of the patient's problems is sickle cell disease and its associated complications. The patient is at risk for further complications such as acute chest syndrome, stroke and infection due to his condition.
Anatomy of anterior_cruciate_ligament_by- dr. armaan singhDr. Armaan Singh
The anterior cruciate ligament (ACL) originates on the posterior medial femoral condyle and inserts on the anterior tibia. It consists of anteromedial and posterolateral bundles that twist during knee flexion. The ACL prevents anterior tibial translation and internal rotation. Injury is common in sports involving pivoting. Females have a higher risk due to narrower intercondylar notches. The posterior cruciate ligament (PCL) is the strongest ligament and prevents posterior tibial translation. Both cruciates receive blood supply from the middle genicular artery and have proprioceptive mechanoreceptors.
This document discusses peripheral vascular diseases, including arteries, veins, and specific conditions like arterial insufficiency and venous insufficiency. It covers the anatomy and layers of arteries and veins. Peripheral vascular diseases are characterized by reduced blood flow and oxygen delivery to tissues. Specific conditions discussed in detail include arteriosclerosis obliterans, thromboangitis obliterans (Buerger's disease), and Raynaud's phenomenon. Risk factors, clinical manifestations, diagnostic tests, and management approaches are described for each condition.
This document discusses cellulitis, including its definition, diagnosis, microbiology, and treatment approaches. It provides guidelines for treating non-purulent versus purulent cellulitis, and recommendations for oral versus intravenous antibiotics. Hospitalization is warranted for extensive or systemic infections, including the case presented of a patient with a large, draining leg wound requiring IV vancomycin.
The document discusses cardiac physiology and anesthetic considerations. It covers the structure of the heart, cardiac cycle, conduction system, blood flow, output and pressures. It describes measurements like ejection fraction, cardiac index and classifications of blood pressure. It discusses the effects of anesthetic agents on the heart and goals of anesthesia for cardiovascular diseases like avoiding tachycardia and hypocapnia.
Immediate changes after death include permanent cessation of brain and circulatory function as well as respiratory function. Early postmortem changes involve cooling of the body, lividity/hypostasis as blood settles in the body, and rigor mortis as the muscles stiffen. Late changes include decomposition of tissues over time. These postmortem changes can help determine time of death and other forensic details.
This document provides information on different types of injuries from a medical-legal perspective. It defines injuries clinically and legally, and classifies mechanical injuries as blunt force injuries (abrasions, contusions, lacerations) or sharp force injuries (incised wounds, stab wounds, chop wounds). For each type of injury, it describes features, age determination, antemortem vs postmortem appearance, and medico-legal aspects. Weapon identification, manner and direction of force application, and wound age determination are important considerations in mechanical injury analysis.
Forensic toxicology is the study of toxic substances and their physiological effects. Toxicologists investigate deaths through postmortem drug testing, workplace drug testing, and identifying contraband. They analyze tissue samples to understand how the body processes toxins and drugs. Common toxic substances include alkaloids like amphetamines, cocaine, opiates, and cannabinoids. Toxicologists use various detection methods like chromatography, spectroscopy, and mass spectroscopy to identify substances and determine cause of death.
The document discusses forensic pathology and autopsy procedures. It describes the role of the forensic pathologist as determining the cause, manner, and time of death through postmortem examination. It outlines the typical steps of an autopsy, including external examination, a Y-shaped incision, examination of organs, and analysis of trauma wounds or other signs that could indicate the cause of death. Key autopsy goals are to examine the body for injuries or diseases that may have led to death.
The document discusses the process and objectives of a medico-legal autopsy. A medico-legal autopsy, also known as a post-mortem examination, is a scientific examination of a dead body that is carried out under state laws to determine the cause and manner of death and assist in legal investigations. It aims to establish the cause, manner, and estimated time of death, as well as identify the deceased individual and collect relevant tissues as evidence. The document outlines the typical process, examinations, and reporting of findings for a medico-legal autopsy.
Asphyxia is a condition caused by lack of oxygen to tissues. It can result from obstruction of air passages, inhalation of toxic gases, respiratory muscle spasms, or problems with the respiratory center of the brain. Common causes include hanging, strangulation, suffocation, and drowning. Features include cyanosis, capillary dilation and stasis, and increased capillary permeability. In hanging, ligature marks and petechial hemorrhages are seen externally, while internal findings include neck hemorrhages and carotid artery tears. Strangulation produces ligature marks and neck muscle injuries. Suffocation causes abrasions around the mouth and nose. Drowning results in fluid inhalation causing lung changes. Medico-
The heart is a muscular organ about the size of a fist that pumps blood through the body. It has four chambers - two upper atria that receive blood and two lower ventricles that pump blood out. Deoxygenated blood enters the right atrium from the body and is pumped to the lungs by the right ventricle. Oxygenated blood returns from the lungs to the left atrium and is pumped by the left ventricle out to the body through the aorta. Valves between the chambers prevent backflow of blood. The conductive system coordinates heart muscle contraction.
Fever is a common complication in ICU patients and can arise from infectious as well as non-infectious causes. The most common infectious causes include ventilator-associated pneumonia (VAP), urinary tract infections (UTI), and bloodstream infections. VAP is diagnosed based on new infiltrates on CXR, fever, and purulent secretions; investigations include quantitative cultures of lower respiratory tract secretions. Clostridium difficile infection is a common cause of diarrhea and is associated with antibiotic use. Sinusitis can occur in intubated patients and requires imaging and drainage for diagnosis. Non-infectious causes of fever include drug reactions, deep vein thrombosis, and inflammatory conditions. Fever
This document discusses anxiety disorders in teenagers. It notes that anxiety disorders are common among children and adolescents, affecting about 13% of youth, and are more prevalent in girls. Anxiety manifests in feelings of dread, fears of catastrophe, and somatic complaints. It outlines several types of anxiety disorders including generalized anxiety disorder, post-traumatic stress disorder, panic disorder, phobias, and obsessive-compulsive disorder. Comorbidity with depression and substance use is also common. The document provides strategies for treating anxiety and supporting anxious students.
The document discusses the skull, brain, cranial nerves and related structures. It provides details on:
1) The bones that make up the skull, their openings and functions in protecting the brain.
2) The meninges and cerebrospinal fluid which surround and nourish the brain and spinal cord.
3) The 12 pairs of cranial nerves, their attachments, functions and pathways through openings in the skull.
4) Key structures of the brain like the cerebrum, brainstem, ventricles and blood supply.
5) Membranes, bones and pathways involved in protecting and supplying the brain.
The document discusses the inpatient management of acute decompensated heart failure. Key points include identifying signs and symptoms of ADHF, obtaining pertinent labs and imaging to evaluate the patient, and treating with intravenous diuretics followed by chronic medications like ACE inhibitors, beta blockers, and spironolactone prior to discharge with close follow up.
This document discusses the management of constipation in adults. Constipation is defined using Rome III criteria as having two of the following: straining, lumpy hard stools, incomplete evacuation, use of digital maneuvers, or less than three bowel movements per week. Therapy includes lifestyle modifications like increased fluid/fiber intake and exercise, as well as laxatives such as stimulants, osmotics, and bulk formers. For the case presented, an appropriate treatment would be the osmotic laxative lactulose.
This document defines different types of pneumonia including community acquired pneumonia (CAP), hospital-acquired pneumonia (HAP), healthcare-associated pneumonia (HCAP), and ventilator-associated pneumonia (VAP). It describes common clinical features, diagnostic testing recommendations including chest radiographs, severity assessment scores, and treatment guidelines based on patient risk factors and pneumonia type. Initial treatment often includes broad-spectrum antibiotics while considering possible multidrug-resistant pathogens, with options to address a lack of improvement such as fungal infections or tuberculosis.
This document provides an overview and guidelines for choosing antibiotics. It discusses collecting cultures before starting antibiotics and ensuring appropriate dosing. Common antibiotics are reviewed including beta-lactams like penicillins, cephalosporins, and carbapenems as well as quinolones, macrolides, and metronidazole. Factors to consider for antibiotic selection include location and type of infection, patient history, and risk of drug-resistant pathogens. Quick guides are provided for coverage of pseudomonas, anaerobes, MRSA, and VRE.
This document discusses renal stone disease. It identifies common risk factors like male sex, obesity, and dietary factors. Typical symptoms include flank pain, nausea, and hematuria. The most common types of stones are calcium oxalate, calcium phosphate, and struvite. Non-contrast CT is the gold standard for imaging. Stones less than 5mm often pass spontaneously, while larger stones may require urologic intervention.
1. The new guidelines recommend initiating moderate or high-intensity statin therapy for patients in four categories based on their cardiovascular risk, rather than targeting a specific LDL-C level.
2. The four categories are: individuals with clinical atherosclerotic cardiovascular disease, LDL-C over 190 mg/dL, diabetes between ages 40-75 with LDL-C 70-189 mg/dL, and 10-year risk over 7.5% for ages 40-75 with LDL-C 70-189 mg/dL.
3. Lipids should be measured during follow-ups to assess adherence, not to achieve a specific target level.
This document discusses relative adrenal insufficiency, a condition where the adrenal glands do not adequately increase cortisol production during physiological stress such as sepsis. It defines relative adrenal insufficiency and explains that testing for it can be unreliable. For patients in sepsis who require vasopressors, the document recommends having a low threshold to treat with hydrocortisone but not fludrocortisone, as it has not been shown to help. The case presented is of a man in sepsis, and the recommended next step is to administer hydrocortisone.
The patient is a 20-year-old male with sickle cell disease who presents with several chronic and acute complications. He has a history of delayed puberty, joint pain, weakness and cough. Examination reveals decreased growth, severe anemia, leg ulcers, enlarged spleen and fever. Laboratory tests show hemoglobin of 8g/dL and reticulocyte count of 25%. The most probable cause of the patient's problems is sickle cell disease and its associated complications. The patient is at risk for further complications such as acute chest syndrome, stroke and infection due to his condition.
Anatomy of anterior_cruciate_ligament_by- dr. armaan singhDr. Armaan Singh
The anterior cruciate ligament (ACL) originates on the posterior medial femoral condyle and inserts on the anterior tibia. It consists of anteromedial and posterolateral bundles that twist during knee flexion. The ACL prevents anterior tibial translation and internal rotation. Injury is common in sports involving pivoting. Females have a higher risk due to narrower intercondylar notches. The posterior cruciate ligament (PCL) is the strongest ligament and prevents posterior tibial translation. Both cruciates receive blood supply from the middle genicular artery and have proprioceptive mechanoreceptors.
This document discusses peripheral vascular diseases, including arteries, veins, and specific conditions like arterial insufficiency and venous insufficiency. It covers the anatomy and layers of arteries and veins. Peripheral vascular diseases are characterized by reduced blood flow and oxygen delivery to tissues. Specific conditions discussed in detail include arteriosclerosis obliterans, thromboangitis obliterans (Buerger's disease), and Raynaud's phenomenon. Risk factors, clinical manifestations, diagnostic tests, and management approaches are described for each condition.
This document discusses cellulitis, including its definition, diagnosis, microbiology, and treatment approaches. It provides guidelines for treating non-purulent versus purulent cellulitis, and recommendations for oral versus intravenous antibiotics. Hospitalization is warranted for extensive or systemic infections, including the case presented of a patient with a large, draining leg wound requiring IV vancomycin.
The document discusses cardiac physiology and anesthetic considerations. It covers the structure of the heart, cardiac cycle, conduction system, blood flow, output and pressures. It describes measurements like ejection fraction, cardiac index and classifications of blood pressure. It discusses the effects of anesthetic agents on the heart and goals of anesthesia for cardiovascular diseases like avoiding tachycardia and hypocapnia.
Immediate changes after death include permanent cessation of brain and circulatory function as well as respiratory function. Early postmortem changes involve cooling of the body, lividity/hypostasis as blood settles in the body, and rigor mortis as the muscles stiffen. Late changes include decomposition of tissues over time. These postmortem changes can help determine time of death and other forensic details.
This document provides information on different types of injuries from a medical-legal perspective. It defines injuries clinically and legally, and classifies mechanical injuries as blunt force injuries (abrasions, contusions, lacerations) or sharp force injuries (incised wounds, stab wounds, chop wounds). For each type of injury, it describes features, age determination, antemortem vs postmortem appearance, and medico-legal aspects. Weapon identification, manner and direction of force application, and wound age determination are important considerations in mechanical injury analysis.
Forensic toxicology is the study of toxic substances and their physiological effects. Toxicologists investigate deaths through postmortem drug testing, workplace drug testing, and identifying contraband. They analyze tissue samples to understand how the body processes toxins and drugs. Common toxic substances include alkaloids like amphetamines, cocaine, opiates, and cannabinoids. Toxicologists use various detection methods like chromatography, spectroscopy, and mass spectroscopy to identify substances and determine cause of death.
The document discusses forensic pathology and autopsy procedures. It describes the role of the forensic pathologist as determining the cause, manner, and time of death through postmortem examination. It outlines the typical steps of an autopsy, including external examination, a Y-shaped incision, examination of organs, and analysis of trauma wounds or other signs that could indicate the cause of death. Key autopsy goals are to examine the body for injuries or diseases that may have led to death.
The document discusses the process and objectives of a medico-legal autopsy. A medico-legal autopsy, also known as a post-mortem examination, is a scientific examination of a dead body that is carried out under state laws to determine the cause and manner of death and assist in legal investigations. It aims to establish the cause, manner, and estimated time of death, as well as identify the deceased individual and collect relevant tissues as evidence. The document outlines the typical process, examinations, and reporting of findings for a medico-legal autopsy.
Asphyxia is a condition caused by lack of oxygen to tissues. It can result from obstruction of air passages, inhalation of toxic gases, respiratory muscle spasms, or problems with the respiratory center of the brain. Common causes include hanging, strangulation, suffocation, and drowning. Features include cyanosis, capillary dilation and stasis, and increased capillary permeability. In hanging, ligature marks and petechial hemorrhages are seen externally, while internal findings include neck hemorrhages and carotid artery tears. Strangulation produces ligature marks and neck muscle injuries. Suffocation causes abrasions around the mouth and nose. Drowning results in fluid inhalation causing lung changes. Medico-
The heart is a muscular organ about the size of a fist that pumps blood through the body. It has four chambers - two upper atria that receive blood and two lower ventricles that pump blood out. Deoxygenated blood enters the right atrium from the body and is pumped to the lungs by the right ventricle. Oxygenated blood returns from the lungs to the left atrium and is pumped by the left ventricle out to the body through the aorta. Valves between the chambers prevent backflow of blood. The conductive system coordinates heart muscle contraction.
Fever is a common complication in ICU patients and can arise from infectious as well as non-infectious causes. The most common infectious causes include ventilator-associated pneumonia (VAP), urinary tract infections (UTI), and bloodstream infections. VAP is diagnosed based on new infiltrates on CXR, fever, and purulent secretions; investigations include quantitative cultures of lower respiratory tract secretions. Clostridium difficile infection is a common cause of diarrhea and is associated with antibiotic use. Sinusitis can occur in intubated patients and requires imaging and drainage for diagnosis. Non-infectious causes of fever include drug reactions, deep vein thrombosis, and inflammatory conditions. Fever
This document discusses anxiety disorders in teenagers. It notes that anxiety disorders are common among children and adolescents, affecting about 13% of youth, and are more prevalent in girls. Anxiety manifests in feelings of dread, fears of catastrophe, and somatic complaints. It outlines several types of anxiety disorders including generalized anxiety disorder, post-traumatic stress disorder, panic disorder, phobias, and obsessive-compulsive disorder. Comorbidity with depression and substance use is also common. The document provides strategies for treating anxiety and supporting anxious students.
The document discusses the skull, brain, cranial nerves and related structures. It provides details on:
1) The bones that make up the skull, their openings and functions in protecting the brain.
2) The meninges and cerebrospinal fluid which surround and nourish the brain and spinal cord.
3) The 12 pairs of cranial nerves, their attachments, functions and pathways through openings in the skull.
4) Key structures of the brain like the cerebrum, brainstem, ventricles and blood supply.
5) Membranes, bones and pathways involved in protecting and supplying the brain.
This document provides guidelines for managing pulmonary hypertension in cardiac surgery patients. It discusses that pulmonary hypertension can increase in the postoperative period due to various factors like SIRS, protamine, hypoxia, hypercarbia, and mechanical ventilation. It recommends avoiding these triggers and using selective pulmonary vasodilators like inhaled nitric oxide, inhaled prostacyclin, inhaled iloprost, and sildenafil to treat pre-capillary pulmonary hypertension. For post-capillary pulmonary hypertension, it suggests improving left ventricular function and using nesiritide to decrease pulmonary artery pressures and improve outcomes.
Postoperative bleeding & guidelines for transfusionDr. Armaan Singh
This document discusses guidelines for transfusion therapy and management of postoperative bleeding in cardiac surgery patients. It provides an overview of factors that can influence bleeding, complications of blood transfusions, and tests to assess coagulation status. The document outlines guidelines for transfusion of blood products like platelets, plasma, cryoprecipitate based on results of coagulation tests or thromboelastography. It also provides guidelines for surgical re-exploration based on chest tube output. Management of massive bleeding and tamponade is discussed.
This document provides clinical practice guidelines for blood conservation strategies in cardiac surgery from the Society of Thoracic Surgeons and The Society of Cardiovascular Anesthesiologists. It recommends various preoperative, intraoperative, and postoperative interventions to reduce bleeding and blood transfusions during cardiac procedures. These include discontinuing antiplatelet agents preoperatively, using antifibrinolytics intraoperatively, and employing blood salvage techniques. The guidelines provide evidence and recommendations for different blood derivative products and perfusion strategies to optimize blood conservation.
The document outlines goals for cardio-circulatory therapy in post-operative cardiac surgery patients. It recommends targeting specific hemodynamic parameters like mean arterial pressure, cardiac index, central venous pressure, and lactate levels. It also discusses guidelines for fluid management in these patients, noting medium molecular weight hydroxyethyl starch derivatives like Voluven are preferred for volume substitution over crystalloids or albumin. Voluven is not associated with increased bleeding or renal failure risks like other colloids at higher doses.
The document provides guidelines for the management of pulmonary hypertension in cardiac surgery patients. It discusses causes of increased pulmonary vascular resistance postoperatively including hypoxia, hypercarbia, acidosis, and pulmonary vasoconstriction. It recommends treating the underlying cause by avoiding factors that cause pulmonary vasoconstriction. For passive pulmonary hypertension, it suggests improving left ventricular contractility and decreasing mitral regurgitation. It also discusses selective pulmonary vasodilators like inhaled nitric oxide, prostacyclin, and iloprost as well as oral sildenafil.
This document provides guidelines for managing right heart failure in cardiac surgery patients. Pulmonary vasoconstriction due to factors like hypoxia, hypercarbia, and pulmonary hypertension can increase right ventricular afterload and precipitate right heart failure. Right ventricular dysfunction can be caused by systolic dysfunction, volume overload, or pressure overload. Right heart failure is manifested by elevated central venous pressure, decreased blood pressure, and decreased cardiac output. Echocardiography can evaluate right ventricular function and pressures. The goals of treatment are to ensure adequate preload, reduce pulmonary vascular resistance, and improve contractility. This involves optimizing ventilation to avoid hypoxemia and hypercarbia, using pulmonary vasodilators, and administer
The document discusses guidelines for managing cardio-circulatory therapy and hemodynamics for cardiac surgery patients, including recommended goals for parameters such as blood pressure, cardiac index, oxygen saturation, and diuresis. It also outlines causes and risks of postoperative hypertension and provides guidance on pharmacological management using intravenous vasodilators, beta blockers, and diuretics to control blood pressure in the postoperative period.
The document provides guidelines for the management of left heart failure in cardiac surgery patients, outlining indicators of cardiocirculatory failure, recommendations for increasing preload and use of vasodilating and inotropic agents, and noting that drugs like nesiritide and levosimendan can help optimize hemodynamics by reducing preload, afterload, and pulmonary vascular resistance.
Guidelines for intraaortic balloon counterpulsationDr. Armaan Singh
The document discusses guidelines for intraaortic balloon counterpulsation (IABP). IABP involves inflating and deflating a balloon in the aorta to assist the heart. Precise timing of balloon inflation and deflation is important. Inflation should occur at the beginning of diastole to increase coronary blood flow and reduce left ventricular workload. Deflation should happen at the beginning of systole to reduce afterload on the heart. Complications can include lower extremity ischemia or damage to the aorta. Guidelines are provided on indications, complications, troubleshooting, and weaning a patient from IABP support.
Insanony: Watch Instagram Stories Secretly - A Complete GuideTrending Blogers
Welcome to the world of social media, where Instagram reigns supreme! Today, we're going to explore a fascinating tool called Insanony that lets you watch Instagram Stories secretly. If you've ever wanted to view someone's story without them knowing, this blog is for you. We'll delve into everything you need to know about Insanony with Trending Blogers!
Confidence is Key: Fashion for Women Over 50miabarn9
Unlock your personal style and confidence at 50 and beyond! Our fashion blog provides actionable tips and inspiration on how to improve your dressing sense according to your body type, skin tone, and personal style, ensuring you look and feel amazing.
MISS RAIPUR 2024 - WINNER POONAM BHARTI.DK PAGEANT
Poonam Bharti, a guide of ability and diligence, has been chosen as the champ from Raipur for Mrs. India 2024, Pride of India, from the DK Show. Her journey to this prestigious title is a confirmation of her commitment, difficult work, and multifaceted gifts. At fair 23 a long time ago, Poonam has as of now made noteworthy strides in both her proficient and individual lives, encapsulating the soul of present-day Indian ladies who adjust different parts with beauty and competence. This article dives into Poonam Bharti’s foundation, achievements, and qualities that separated her as a meriting champion of this award.
MISS TEEN LUCKNOW 2024 - WINNER ASIYA 2024DK PAGEANT
In the dynamic city of Lucknow, known for its wealthy social legacy and authentic importance, a youthful star has developed, capturing the hearts of numerous with her elegance, insights, and eagerness. Asiya, as of late delegated as the champ from Lucknow for Miss Youngster India 2024 by the DK Pageant, stands as a confirmation of the monstrous ability and potential dwelling inside the youth of India. This exceptional young lady is a signal of excellence and a paragon of devotion and aspiration.
Biography and career history of Bruno AmezcuaBruno Amezcua
Bruno Amezcua's entry into the film and visual arts world seemed predestined. His grandfather, a distinguished film editor from the 1950s through the 1970s, profoundly influenced him. This familial mentorship early on exposed him to the nuances of film production and a broad array of fine arts, igniting a lifelong passion for narrative creation. Over 15 years, Bruno has engaged in diverse projects showcasing his dedication to the arts.
Amid the constant barrage of distractions and dwindling motivation, self-discipline emerges as the unwavering beacon that guides individuals toward triumph. This vital quality serves as the key to unlocking one’s true potential, whether the aspiration is to attain personal goals, ascend the career ladder, or refine everyday habits.
Understanding Self-Discipline