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The health hazards inherent to commercial meat-based companion animal diets are extensive and difficult to avoid, and can include slaughterhouse waste, supermarket rejects, restaurant grease, fish contaminants, endotoxins, mycotoxins, and toxic chemicals. Unsurprisingly, studies have identified kidney, liver, heart, neurologic, visual, neuromuscular and skin diseases, bleeding disorders, birth defects, immunocompromisation and infectious diseases associated with meat-based diets. There is no scientific reason why a diet comprised only of plant, mineral and synthetically-based ingredients cannot be formulated to meet all of the nutritional requirements of cats and dogs, and several commercially-available vegan diets claim to do so. Health benefits commonly observed include decreased skin parasites and improved coat condition, allergy control, weight and arthritis control, and improved vitality. Correct use of a complete and balanced nutritional supplement is essential, however, to avoid potentially severe health problems, particularly in cats, and monitoring of urinary acidity is strongly advisable. These topics will be explored in greater detail, and are described at www.vegepets.info.