Microteaching Lesson

2. How to conduct
an fMRI experiment
in cognitive neuroscience
Ana Luísa Pinho
August 10, 2023
Department of Computer Science and Western Institute for Neuroscience
agrilopi@uwo.ca

3. fMRI = functional Magnetic Resonance Imaging
How to conduct an fMRI experiment in cognitive neuroscience

4. The Missile Effect
How to conduct an fMRI experiment in cognitive neuroscience

5. Before the experiment
How to conduct an fMRI experiment in cognitive neuroscience

6. Before the experiment
1 Prescreening during recruitment
How to conduct an fMRI experiment in cognitive neuroscience

7. Before the experiment
1 Prescreening during recruitment
2 Fill MRI-safety questionnaire
How to conduct an fMRI experiment in cognitive neuroscience
Centre for Functional and Metabolic Mapping (CFMM)

8. Before the experiment
1 Prescreening during recruitment
2 Fill MRI-safety questionnaire
3 Sign a consent form
How to conduct an fMRI experiment in cognitive neuroscience
Centre for Functional and Metabolic Mapping (CFMM)

9. Before the experiment
1 Prescreening during recruitment
2 Fill MRI-safety questionnaire
3 Sign a consent form

MRI exclusion criteria
How to conduct an fMRI experiment in cognitive neuroscience
Centre for Functional and Metabolic Mapping (CFMM)

10. Before the experiment
1 Prescreening during recruitment
2 Fill MRI-safety questionnaire
3 Sign a consent form

MRI exclusion criteria

Benefits
How to conduct an fMRI experiment in cognitive neuroscience
Centre for Functional and Metabolic Mapping (CFMM)

11. Before the experiment
1 Prescreening during recruitment
2 Fill MRI-safety questionnaire
3 Sign a consent form

MRI exclusion criteria

Benefits

Compensation
How to conduct an fMRI experiment in cognitive neuroscience
Centre for Functional and Metabolic Mapping (CFMM)

12. Before the experiment
1 Prescreening during recruitment
2 Fill MRI-safety questionnaire
3 Sign a consent form

MRI exclusion criteria

Benefits

Compensation

Voluntary Participation / Withdrawal
How to conduct an fMRI experiment in cognitive neuroscience
Centre for Functional and Metabolic Mapping (CFMM)

13. Before the experiment
1 Prescreening during recruitment
2 Fill MRI-safety questionnaire
3 Sign a consent form

MRI exclusion criteria

Benefits

Compensation

Voluntary Participation / Withdrawal

Risks
How to conduct an fMRI experiment in cognitive neuroscience
Centre for Functional and Metabolic Mapping (CFMM)

14. Before the experiment
1 Prescreening during recruitment
2 Fill MRI-safety questionnaire
3 Sign a consent form

MRI exclusion criteria

Benefits

Compensation

Voluntary Participation / Withdrawal

Risks

Confidentiality
How to conduct an fMRI experiment in cognitive neuroscience
Centre for Functional and Metabolic Mapping (CFMM)

15. Before the experiment
1 Prescreening during recruitment
2 Fill MRI-safety questionnaire
3 Sign a consent form

MRI exclusion criteria

Benefits

Compensation

Voluntary Participation / Withdrawal

Risks

Confidentiality
How to conduct an fMRI experiment in cognitive neuroscience
Centre for Functional and Metabolic Mapping (CFMM)

16. The Setup: Control Room
MRI Station Stimulus
Presentation
MRI 3T Scanner
NeuroSpin, CEA,
Paris-Saclay,
France
How to conduct an fMRI experiment in cognitive neuroscience

17. The Setup: MRI Scanner
How to conduct an fMRI experiment in cognitive neuroscience
The Faraday Cage
MRI Antenna + Mirror
MRI 3T Scanner, NeuroSpin, CEA, Paris-Saclay, France

18. Placing the Participant in the Scanner
How to conduct an fMRI experiment in cognitive neuroscience
The participant is provided with:

Headset

Response box

Alarm Ball

19. Running the Scan
Scan sequence Localizer Scan
How to conduct an fMRI experiment in cognitive neuroscience

20. High-Resolution Anatomical Scan
How to conduct an fMRI experiment in cognitive neuroscience
T1-weighted Image

21. Functional Sequences:
selecting the Field-of-View (FoV)
How to conduct an fMRI experiment in cognitive neuroscience

22. Functional Scans: EPI Sequence
EPI = Echo-Planar Imaging
Among many parameters, we must choose the
Repetition Time (TR) ~ few seconds
How to conduct an fMRI experiment in cognitive neuroscience

23. Functional Scans: EPI Sequence
EPI = Echo-Planar Imaging
How to conduct an fMRI experiment in cognitive neuroscience

24. Summary & Resources
How to conduct an fMRI experiment in cognitive neuroscience

25. Summary & Resources

Recruitment:
How to conduct an fMRI experiment in cognitive neuroscience
1 Eligibility Criteria
2 MRI-Safety Procedures
3 Consent Form

26. Summary & Resources

Recruitment:
How to conduct an fMRI experiment in cognitive neuroscience
1 Eligibility Criteria
2 MRI-Safety Procedures
3 Consent Form
https://uwo.ca/research/ethics/human/board_guidelines.html
Western Guidelines&Templates

27. Summary & Resources

Recruitment:

Overview of the MRI Control-Room
How to conduct an fMRI experiment in cognitive neuroscience
1 Eligibility Criteria
2 MRI-Safety Procedures
3 Consent Form
https://uwo.ca/research/ethics/human/board_guidelines.html
Western Guidelines&Templates

28. Summary & Resources

Recruitment:

Overview of the MRI Control-Room

Overview of the MRI Scanner
How to conduct an fMRI experiment in cognitive neuroscience
1 Eligibility Criteria
2 MRI-Safety Procedures
3 Consent Form
https://uwo.ca/research/ethics/human/board_guidelines.html
Western Guidelines&Templates

29. Summary & Resources

Recruitment:

Overview of the MRI Control-Room

Overview of the MRI Scanner

Placing the Participant inside the MRI Scanner
How to conduct an fMRI experiment in cognitive neuroscience
1 Eligibility Criteria
2 MRI-Safety Procedures
3 Consent Form
https://uwo.ca/research/ethics/human/board_guidelines.html
Western Guidelines&Templates

30. Summary & Resources

Recruitment:

Overview of the MRI Control-Room

Overview of the MRI Scanner

Placing the Participant inside the MRI Scanner

Running an experiment:
How to conduct an fMRI experiment in cognitive neuroscience
1 Run Localizer
2 Run T1-weighted anatomical sequence
3 Set FoV
4 Run EPI
1 Eligibility Criteria
2 MRI-Safety Procedures
3 Consent Form
https://uwo.ca/research/ethics/human/board_guidelines.html
Western Guidelines&Templates

31. Summary & Resources

Recruitment:

Overview of the MRI Control-Room

Overview of the MRI Scanner

Placing the Participant inside the MRI Scanner

Running an experiment:
How to conduct an fMRI experiment in cognitive neuroscience
1 Run Localizer
2 Run T1-weighted anatomical sequence
3 Set FoV
4 Run EPI
1 Eligibility Criteria
2 MRI-Safety Procedures
3 Consent Form
https://uwo.ca/research/ethics/human/board_guidelines.html
Functional Magnetic Resonance Imaging
Third Edition
Scott A. Huettel, Allen W. Song, and Gregory
McCarthy
Oxford University Press
Western Guidelines&Templates

32. Summary & Resources

Recruitment:

Overview of the MRI Control-Room

Overview of the MRI Scanner

Placing the Participant inside the MRI Scanner

Running an experiment:
How to conduct an fMRI experiment in cognitive neuroscience
1 Run Localizer
2 Run T1-weighted anatomical sequence
3 Set FoV
4 Run EPI
1 Eligibility Criteria
2 MRI-Safety Procedures
3 Consent Form
https://uwo.ca/research/ethics/human/board_guidelines.html
Functional Magnetic Resonance Imaging
Third Edition
Scott A. Huettel, Allen W. Song, and Gregory
McCarthy
Oxford University Press
Western Guidelines&Templates
Next Lesson:
How to design a stimulus presentation?