Veterinary Pathology of The Male Genital System

1. Veterinary Pathology of
The Male Genital System

2. • LH – Leydig cells – testosterone –
interstitial space---Leyding cell tumor
• FSH + testosterone – seminiferous tubules
(spermatogonia) – spermatozoa
– Production of structurally abnormal
spermatozoa and ratio N and AN

3. Penis and Prepuce
• Hypoplasia after castration or intersex states
• Supernumery and ectopic penis
• Contraction of ischiocavernosus muscle allow
arterial input to the corpus cavernosum and
sponiosum, but occludes venous drainage
– Rupture of corpus cavernosum causing hemorrhage
– Vascular shunts from corpus cavernosum to the
corpus spongiosum of the penis or peripenile
vasculature
– Rupture of corpus cavernosum in stallion

4. Surgical Condition of Prepuce
• Varicosities of preputal veins in stallion
• Eversion of preputial mucosa
• Phimosis..very small preputial opening
Paraphimosis..penile swelling
• – inability of penile retraction – trauma
(inflammation or paralysis), tranquilizers

5. TVT
• Transmissible venereal tumor
– Uncertain Histogenesis
– Living cells transfer
– Present on Penis and less commonly on
prepuce
– Transferred to bitch by coitus
– Surgically removed
– Complete removal result in recovery

6. Inflammation of the Penis and
prepuce (Balanoposthitis)
• Blanitis
• Posthitis
• Parainfluenza-3, herpes virus,
Corynebacterium renale, Haemophilus
somnus, fungi, mycoplasmas, Ureplasma
diversum, Trypanosoma equiperdum
• Lymphoplasmacytic infiltrations of
preputial mucosa, varying type of exudate,
necrotic mucosa, ulcers
• Squamous cell carcinoma…Horses

7. Testes
• Hypoplasia – cryptorchidism, intersex states,
chronic diseases, malnutrition, chromosomal
anomalies
• Degeneration – disturbed spermatogenesis –
increases followed by decrease in size – ionizing
radiation, cryptorchidal and ectopic testes,
excessive scrotal fat, localized or systemic
infections, general or specific nutritional
deficiencies (vit. A, zinc), torsion of the cord,
infarction, hormonal imbalances

8. Orchitis
• Interstitial – may not be recognized
grossly, microscopically infiltrations
leading to fibrosis – infectious or immune
• Intratubular – solitary or multiple white-
yellow foci – ascending infection
• Necrotizing – Brucellosis and other
infections, trauma, or ischemia –
coagulative necrosis