2. MITOSIS :
Mitosis is a part of the cell cycle in which
replicated chromosomes are separated into
two new nuclei.
Mitosis came from the greek word mitos
means “warp thread” .
3. DISCOVERY OF MITOSIS :
In animal cells, cell division with mitosis was
discovered in frog, rabbit, and
cat cornea cells in 1873 described for the
first time by the Polish histologist Wacław
Mayzel in 1875.
Walther Flemming ,a german scientist
discovered mitosis in the year 1882,
in the animal cell.
6. PROPHASE :
During prophase, the cell prepares to divide
by tightly condensing its chromosomes and
initiating mitotic spindle formation.
At the onset of prophase, chromatin fibers
condense into discrete chromosomes that are
typically visible at high magnification
through a light microscope. In this stage,
chromosomes are long, thin, and thread-like
structure.
7. Here Nuclear envelope breakdown and
centrosomes moves towards the opposite
poles.
Each replicated chromosome comprises two
chromatids, both with the same genetic
information.
8. METAPHASE :
Chromosomes are lined up at the mtaphase
plate.
A large protein network called spindle
attaches to each sister chromatid and
orginates at the opposite poles.
These chormosomes are aligned in the
perpendicular way in the spindle and this
process is said to be metaphase.
9.
10. ANAPHASE :
In this stage the centromeres of the chromatids
begin to split into opposite poles being
effectively increasing the number of
chromosomes.
During anaphase polar microtubules push
against each other, causing the cell to elongate.
In late anaphase, chromosomes also reach their
overall maximal condensation level, to
help chromosome segregation and the re-
formation of the nucleus .
11.
12. TELOPHASE:
Chromosomes arrive at opposite poles and began
to decondese.
At telophase, the polar microtubules continue to
lengthen, elongating the cell even more.
The new envelope forms around each set of
separated daughter chromosomes and the
nucleus reappears.
Each daughter nucleus has an identical set of
chromosomes. Cell division may or may not
occur at this time depending on the organism.