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A D E W I J A Y A , M D – N O V E M B E R 2 0 2 1
Anastomosis between
Median and Ulnar Nerve
in The Forearm and Hand
4 Major Classifications
Forearm
Martin-Gruber
anastomosis
(MGA)
Marinacci
anastomosis
(MA)
Hand
Riche-Cannieu
anastomosis
(RCA),
Berrettini
anastomosis (BA)
Smith, J. L., Siddiqui, S. A., & Ebraheim, N. A. (2019). Comprehensive summary of anastomoses between the median and ulnar nerves in the forearm and hand. Journal of hand and
microsurgery, 11(01), 001-005.
Clinical Importance
 Presentation of musculoskeletal disorders
 Surgical outcomes
 Surgical approaches
Smith, J. L., Siddiqui, S. A., & Ebraheim, N. A. (2019). Comprehensive summary of anastomoses between the median and ulnar nerves in the forearm and hand. Journal of hand and
microsurgery, 11(01), 001-005.
Martin-Gruber Anastomosis (MGA)
 Prevalence: 19.5 – 27 %
 More common: unilateral; right side
 Autosomal dominant
 Bilateral presentation: Trisomy 21
 Proximal extension of the median nerve or its
branches to the ulnar nerve distally mainly motor
fibers
Smith, J. L., Siddiqui, S. A., & Ebraheim, N. A. (2019). Comprehensive summary of anastomoses between the median and ulnar nerves in the forearm and hand. Journal of hand and
microsurgery, 11(01), 001-005.
MN: median nerve, UN: ulnar NERVE, FDP: Flexor digitorum profundus, FDS: Flexor digitorum superficialis, AIN: anterior interosseous nerve, CB: communicating branch.
E Herrera et al. Salud UIS.,2009, 41, 157-168
Electrophysiology
Sur A, Sinha MM, Ughade JM. Prevalence of Martin-Gruber Anastomosis in Healthy Subjects: An Electrophysiological Study from Raigarh, Chhattisgarh. Neurol India
2021;69:950-5
Marinacci Anastomosis
 0.7 - 4 %
 Reverse MGA, with the ulnar nerve branching
proximally to join the median nerve distally
 Mainly motor fibers
Meenakshi-Sundaram S, Sundar B, Arunkumar M J. Marinacci communication: an electrophysiological study. Clin Neurophysiol. 2003;114(12):2334–2337.
Hopf H C. Forearm ulnar-to-median nerve anastomosis of sensory axons. Muscle Nerve. 1990;13(07):654–656.
Riche–Cannieu Anastomosis
 55.5 – 100 %
 Autosomal dominant
 An interconnection between the recurrent branch of
the median nerve and the deep branch of the ulnar
nerve
 Both motor and sensory fibers may be involved
Smith, J. L., Siddiqui, S. A., & Ebraheim, N. A. (2019). Comprehensive summary of anastomoses between the median and ulnar nerves in the forearm and hand. Journal of hand and
microsurgery, 11(01), 001-005.
Riche–Cannieu Anastomosis
 Three possible
presentations exist:
- A hand may be completely
supplied by the ulnar nerve
- A hand with all motor
innervation via the ulnar
nerve
- A hand with normally
median-innervated
muscles partially supplied
by the ulnar nerve
Smith, J. L., Siddiqui, S. A., & Ebraheim, N. A. (2019). Comprehensive summary of anastomoses between the median and ulnar nerves in the forearm and hand. Journal of hand and
microsurgery, 11(01), 001-005.
Berretini Anastomosis
 60.9 – 80 %
 Neural connection between common digital nerves of
the ulnar and median nerves
 Pure sensory
Unver Dogan N, Uysal I, Seker M. The communications between the ulnar and median nerves in upper limb. Neuroanatomy. 2009;8:15–19.
Roy J, Henry B M, PĘkala P A et al.Median and ulnar nerve anastomoses in the upper limb: A meta-analysis. Muscle Nerve. 2016;54(01):36–47.
Smith, J. L., Siddiqui, S. A., & Ebraheim, N. A. (2019). Comprehensive summary of anastomoses between the median and ulnar nerves in the forearm and hand. Journal of hand and
microsurgery, 11(01), 001-005.
Wakode, S. L., Ravi, N., & Agrawal, A. (2020). Electrodiagnostic description of a rare variant of Berrettini anastomois: A case report. International Journal of Surgery Case Reports, 76, 404-408.
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Anastomosis between Median and Ulnar Nerve in The Forearm and Hand

  • 1. A D E W I J A Y A , M D – N O V E M B E R 2 0 2 1 Anastomosis between Median and Ulnar Nerve in The Forearm and Hand
  • 2. 4 Major Classifications Forearm Martin-Gruber anastomosis (MGA) Marinacci anastomosis (MA) Hand Riche-Cannieu anastomosis (RCA), Berrettini anastomosis (BA) Smith, J. L., Siddiqui, S. A., & Ebraheim, N. A. (2019). Comprehensive summary of anastomoses between the median and ulnar nerves in the forearm and hand. Journal of hand and microsurgery, 11(01), 001-005.
  • 3. Clinical Importance  Presentation of musculoskeletal disorders  Surgical outcomes  Surgical approaches Smith, J. L., Siddiqui, S. A., & Ebraheim, N. A. (2019). Comprehensive summary of anastomoses between the median and ulnar nerves in the forearm and hand. Journal of hand and microsurgery, 11(01), 001-005.
  • 4. Martin-Gruber Anastomosis (MGA)  Prevalence: 19.5 – 27 %  More common: unilateral; right side  Autosomal dominant  Bilateral presentation: Trisomy 21  Proximal extension of the median nerve or its branches to the ulnar nerve distally mainly motor fibers Smith, J. L., Siddiqui, S. A., & Ebraheim, N. A. (2019). Comprehensive summary of anastomoses between the median and ulnar nerves in the forearm and hand. Journal of hand and microsurgery, 11(01), 001-005.
  • 5. MN: median nerve, UN: ulnar NERVE, FDP: Flexor digitorum profundus, FDS: Flexor digitorum superficialis, AIN: anterior interosseous nerve, CB: communicating branch. E Herrera et al. Salud UIS.,2009, 41, 157-168
  • 6. Electrophysiology Sur A, Sinha MM, Ughade JM. Prevalence of Martin-Gruber Anastomosis in Healthy Subjects: An Electrophysiological Study from Raigarh, Chhattisgarh. Neurol India 2021;69:950-5
  • 7. Marinacci Anastomosis  0.7 - 4 %  Reverse MGA, with the ulnar nerve branching proximally to join the median nerve distally  Mainly motor fibers Meenakshi-Sundaram S, Sundar B, Arunkumar M J. Marinacci communication: an electrophysiological study. Clin Neurophysiol. 2003;114(12):2334–2337. Hopf H C. Forearm ulnar-to-median nerve anastomosis of sensory axons. Muscle Nerve. 1990;13(07):654–656.
  • 8. Riche–Cannieu Anastomosis  55.5 – 100 %  Autosomal dominant  An interconnection between the recurrent branch of the median nerve and the deep branch of the ulnar nerve  Both motor and sensory fibers may be involved Smith, J. L., Siddiqui, S. A., & Ebraheim, N. A. (2019). Comprehensive summary of anastomoses between the median and ulnar nerves in the forearm and hand. Journal of hand and microsurgery, 11(01), 001-005.
  • 9. Riche–Cannieu Anastomosis  Three possible presentations exist: - A hand may be completely supplied by the ulnar nerve - A hand with all motor innervation via the ulnar nerve - A hand with normally median-innervated muscles partially supplied by the ulnar nerve Smith, J. L., Siddiqui, S. A., & Ebraheim, N. A. (2019). Comprehensive summary of anastomoses between the median and ulnar nerves in the forearm and hand. Journal of hand and microsurgery, 11(01), 001-005.
  • 10. Berretini Anastomosis  60.9 – 80 %  Neural connection between common digital nerves of the ulnar and median nerves  Pure sensory Unver Dogan N, Uysal I, Seker M. The communications between the ulnar and median nerves in upper limb. Neuroanatomy. 2009;8:15–19. Roy J, Henry B M, PĘkala P A et al.Median and ulnar nerve anastomoses in the upper limb: A meta-analysis. Muscle Nerve. 2016;54(01):36–47.
  • 11. Smith, J. L., Siddiqui, S. A., & Ebraheim, N. A. (2019). Comprehensive summary of anastomoses between the median and ulnar nerves in the forearm and hand. Journal of hand and microsurgery, 11(01), 001-005.
  • 12. Wakode, S. L., Ravi, N., & Agrawal, A. (2020). Electrodiagnostic description of a rare variant of Berrettini anastomois: A case report. International Journal of Surgery Case Reports, 76, 404-408.