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Kenya Higgs 2.9.2016
1. ASTMH in Kenya
6th KEMRI Annual Scientific and Health
(KASH) Conference
Nairobi, Kenya. February 9, 2016
Stephen Higgs, PhD, FRES, FASTMH
President
American Society of Tropical Medicine and Hygiene
Director, Biosecurity Research Institute, Kansas State University
5. Why did the United States need
a society focusing on tropical
medicine and hygiene?
6. 18th-19th Centuries
• Yellow fever epidemics in US and Europe linked to
colonial development and the slave trade
• Most dreaded disease in North America
• 500,000 cases, 100,000 deaths total
• Texas to New England affected
• Napoleon abandons conquests after 23,000 troops
die in Haiti
8. Carlos Juan Finlay (1833 - 1915)
Son of a Scottish doctor and a
Parisienne, born in Cuba but
received early schooling in France
Jefferson Medical College Graduate
Practiced medicine and
ophthalmology in Havana
Became fascinated with the
transmissibility of yellow fever, and
that the agent of disease was in the
air
9. Aedes aegypti & Carlos Finlay
Finlay hypothesizes that the common
house mosquito transmits Yellow Fever
by directly injecting the blood from an
infected person.
Does not appreciate need for extrinsic
incubation period in mosquito after
taking an infected blood meal.
In retrospect, at most only 1 of his 104
experiments from 1881-1898
demonstrates mosquito transmission of
Yellow Fever. Many thought Finlay
disproved his hypothesis.
10. Spanish American War, 1898
Casualties
• 260 die in battleship Maine explosion
• 968 die in combat
• 5000+ die of disease, mostly yellow fever
11. United States Army Yellow Fever
Commission- 1900 -1901
• Mosquito (Ae. aegypti) transmission (volunteer studies)
• Incubation period 3-6 days
• Extrinsic incubation period in mosquito required (12 days)
• Filterable virus
• Not transmissible by air, contact, fomites
14. William Crawford Gorgas letter to
Henry Rose Carter, Dec 13, 1900
“Evidence seems to
point very strongly to the
mosquito being
the transmitter of the
disease.”
15. William Crawford Gorgas
1854-1920 1904: Gorgas’ team arrives in
Panama—within a month all
contracted malaria— Gorgas’
urgent requests are ignored by
Canal authorities
March 1905: Yellow fever outbreak causes a
panic in Panama, most
American canal workers flee
and work is virtually halted
July 1905: Stevens arrives as new Chief
Engineer in Panama and
Gorgas’ public health efforts
are given top priority
Dec 1905: Yellow fever eliminated from
Panama
16. Mosquito control gangs working on
Panama Canal, 1905
Spraying oil in a
ditch
Panama, 1906
19. The ASTMH was originally founded
as the Society of Tropical Medicine
of Philadelphia - by 28 physicians
on March 9, 1903
Twelve days later name was
changed to the American Society of
Tropical Medicine
March 21, 1904
First meeting held at the College
of Physicians in Philadelphia
20. ASTMH: Evolution
1903
1916
Am. Soc. Trop.
Med (1903)
1942
National
Malaria
Committee
(1916)
1952
Renamed
National Malaria Society
Soc. Trop. Med.
Philadelphia
(1903)
21. Thomas H. Fenton (May 28, 1856 – February 23, 1929)
1st President, American Society of Tropical
Medicine
“Dr. Thomas H.
Fenton,” by Thomas
Eakins, 1905
Delaware Art Museum,
Wilmington, Delaware
“My Father, Thomas H. Fenton, M.D.”
by Beatrice Fenton (1887 – 1983)
23. 1900: Graduated MS A&M, Bachelor of Science in
Agriculture; 1901: Master of Arts in Botany
1904: Lecturer on mosquitoes and disease at Army
Medical Museum, Washington, DC
1908: received Doctor of Philosophy. Dissertation
entitled “The Mosquitoes of the Philippine Islands: The
Distribution of Certain Species and Their Occurrence
in Relation to the Incidence of Certain Diseases”
1908: was elected to ASTM, being the 1st female and
1st non-physician member
1916-1920: anatomist at Army Medical Museum of
Health and Medicine, Washington DC
First woman known to have published extensively on
the taxonomy of mosquitoes
.
Clara Southmayd Ludlow
1908: 1st Female Member, 1st Non-Physician
Scientist Member
24. Total membership in the ASTM
1903 - 1951
0
200
400
600
800
1000
1200
1400
1900 1910 1920 1930 1940 1950
Year
Members
WWII
26. Varicella-zoster virus
Thomas Huckle Weller (1915-2008)
Thomas H. Weller (1915-2008)
Discovery of varicella-zoster virus (chickenpox)
Development of cell cultures for polio and attenuation
by serial passage for vaccine
31. LuAnne Elliott in first positive pressure
maximum containment suit, invented by
Karl Johnson CDC, 1977
Karl M. Johnson
Development of civilian high-containment virology
laboratories
35. ASTMH: The Journal
1903 1913 1916 1921
Am. Soc.
Trop. Med
(2003)
1942
National Malaria
Committee
(1916)
Am. J. Tropical Med.
Southern
Medical J.
1952
Renamed
National Malaria Society
Am. J. Trop. Med. & Hyg.
Am J Trop Dis & Preventative Med.
J. Nat.
Malaria
Soc.
Southern Med.
Assoc. (1906)
1908
39. Forty six manuscripts submitted in 2015
with corresponding author from Africa
Burkina Faso 1
Chad 1
Guinea 1
Swaziland 1
Tanzania 1
Tunisia 1
Zambia 1
Zimbabwe 1
Gabon 2
Ghana 2
Mozambique 2
Senegal 2
Kenya 3
Mali 3
Rwanda 3
Sudan 3
Egypt 4
Nigeria 6
Ethiopia 8
40.
41. AJTMH website traffic 2015
Country Visits
United States 194,941
India 42,860
UK 42,438
Brazil 35,635
Australia 20,151
Canada 18,763
China 14,979
Thailand 15,371
Indonesia 13,095
France 13,552
43. The ASTMH is the
largest international
scientific organization
of experts dedicated to
reducing the worldwide
burden of tropical
infectious diseases
and improving global
health.
44. · American Committee on Arthropod-Borne Viruses (ACAV)
· American Committee of Medical Entomology (ACME)
· American Committee on Clinical Tropical Medicine and
Travelers' Health (ACCTMTH)
· American Committee of Molecular, Cellular and
Immunoparasitology (ACMCIP)
· ASTMH Committee on Global Health (ACGH)
ASTMH’s 5 Subgroups (specialized interest areas)
46. ASTMH Membership: 1 October 2015
23%:
Pre & Post Doctoral
11%: Low/Low-Mid
Income
35%: International
(non-US)
All segments are
growing
47. African Representation in ASTMH*
Angola
Benin
Burkina Faso
Cameroon
Cote d'Ivoire
Democratic Republic
of the Congo
Ethiopia
Gabon
Gambia
Ghana
Guinea
Kenya
Liberia
Madagascar
Malawi
Mali
Mozambique
Nigeria
Rwanda
Samoa
Senegal
Sierra Leone
South Africa
Swaziland
Tanzania
Togo
Tunisia
Uganda
Zambia
Zimbabwe
• 11% of ASTMH members
are from Africa
• 35 members from Kenya
• 39 African Travel Award
Recipients in 2015; 7 from
Kenya
*as of 28 January 2016
New in 2014
$25 US -- membership dues
for Low/Low-Middle Income
Countries
48. ASTMH 2015 Annual Meeting
Kenyan presenters:
39 presentations (oral and posters)
3 by travel awardees
49. “We can look forward with confidence to a
considerable degree of freedom from infectious
diseases at a time not too far in the future.
Indeed… it seems reasonable to anticipate that
within some measurable time… all major infections
will have disappeared.”
~Aidan Cockburn
The Evolution and Eradication of Infectious Diseases
(1963)
Premature Declaration of Victory Over
Infectious Diseases
51. Morens et al Nature 430,242 (2004) Figure 1 Global examples of emerging and re-emerging infectious diseases, some of which
are discussed in the main text. Red represents newly emerging diseases; blue, re-emerging/ resurging diseases; black, a
'deliberately emerging' disease. Adapted, with permission, from ref. 23.
Emerging and Re-emerging Diseases
52. Numbers in millions
Infectious Diseases (14.9)
Cardiovascular conditions (16.7)
Neoplastic diseases (7.1)
Injuries (5.2)
Asthma and COPD (3.0)
All others causes of death (57.0)
Infectious Disease: The Toll on Human Health
Infectious diseases cause ~ 26% of all deaths worldwide
Source: WHO 2006
54. “As a society, we should
engage international scientific
and professional
organizations to develop
more opportunities for
training, education, advocacy,
and collaboration.”
55. “Our more junior members, and young
clinicians and scientists, are the future of
ASTMH and it is our responsibility to help
them develop contacts and collaborations in
the field that are beneficial to their careers.
We should expand our reach to attract
younger members by providing
opportunities for them to participate in
career development programs and training.”
76. · American Committee on Arthropod-Borne Viruses (ACAV)
· American Committee of Medical Entomology (ACME)
· American Committee on Clinical Tropical Medicine and
Travelers' Health (ACCTMTH)
· American Committee of Molecular, Cellular and
Immunoparasitology (ACMCIP)
· ASTMH Committee on Global Health (ACGH)
ASTMH’s 5 Subgroups (specialized interest areas)
82. Annual Meeting
• International forum for exchange of latest tropical
medicine/global health advances; 4,000+ attendees from
almost 100 countries.
Networking
• Connect with respected leaders in the field in person at
the Annual Meeting; stay connected through the Society’s
five subgroups; engage via social media
American Journal of Tropical Medicine and Hygiene
• Among top-ranked tropical medicine journals in world; 2/3
of submissions from outside US; average 65,000+
monthly website visits
ASTMH: Your Professional Home
83. Striving for Excellence
• Update Course in Clinical Tropical Medicine and
Travelers’ Health; CTropMed®; Fellow of the American
Society of Tropical Medicine and Hygiene (FASTMH)
Making the Case to US Congress for Strong Funding for
Tropical Medicine/Global Health
• Providing expert testimony; Hill events and visits with
Members of Congress; collaboration with coalition
partners; advocating for strong US funding for tropical
medicine/global health
ASTMH: Your Professional Home
84. • Run for elected positions* of Councilor and President
• Annual Meeting Travel Award - qualified students, early
career investigators and scientists actively working in the
tropical medicine field
• Young Investigator Award
• Honorary International Fellow of ASTMH (non-U.S.
citizens only)
• Apply for Certificate of Knowledge in Clinical Tropical
Medicine and Travelers' Health Examination (CTropMed®)
• Apply for Fellow of ASTMH* (FASTMH)
International Opportunities*
* Open only to members