OMETM is a new mobile app that uses artificial intelligence and a person's genetic and health data to provide personalized healthcare information and recommendations. It aims to help consumers better understand and manage their health by answering questions in everyday language and giving tailored advice that takes into account factors like medical history, lifestyle, and genetic variants. As more users interact with the app, it will become more accurate over time through dynamic learning. The goal is to empower individuals to take a more active role in their healthcare by making complex medical data easily accessible and actionable.

1. OME™: Mobile Cognitive Healthcare
for the Consumer
Michael Nova, M.D.
Chief Innovation Officer
Pathway Genomics

2. 90 OF ALL THE WORLD’S DATA
BIG DATA AND ‘OMICS
IN MEDICINE
WAS CREATED IN THE LAST 2 YEARS
DOUBLES EVERY 3 YEARS,
%
MEDICAL INFORMATION
and by 2020 will double every 3 days.

3. DATA IS
WORTHLESS…
UNLESS IT CAN
BE ANALYZED
AND ACTED ON.

4. Whole
genome
sequence
All the word’s
recorded music
as of 2011
Library of congress
digital holdings as
of 2012
Weather modeling
anticipated to produce
first single-discipline
exabyte dataset
In 2010 the world
produced 1.27b
IS BIG (DATA)?
HOW BIG

5. A Single Person’s
HEALTH DATA
55
…”a single person will generate 1 million gigabytes (1 Terabyte) of
health-related data across his or her lifetime. That’s as much data as
in 300 million books.” Rob Merkel, IBM, 2015

6. Big Data Healthcare Cost Saving

7. Healthcare
TRANSFORMATION
7
We believe Healthcare Transformation revolves around three business
trends and two key opportunities for differentiation…
Evolution of Care
Delivery
Data + Ecosystem
Convergence
Movement to
Consumerism
Game Changing Analytical Insight
“What should I do?”
Flexible Adoption of Business Models
Mobile, TeleHealth, Cognitive
TRENDSOPPORTUNITIES

8. The Human
GENOME AND MEDICAL DATA
8
22,000 GENES
6 BILLION
DNA LETTERS 49CHROMOSOMES
$1,000
COST TO SEQUENCE
OF PATIENT’S PERMANENT
HEALTH RECORD IS MADE UP
OF CLINICAL LABORATORY
T E S T D A T A
70%

9. Healthcare
TRENDS
9

10. Healthcare Costs Driven by Obesity
74% of all costs are confined to obesity and related conditions

11. Mobile Tech
AN APP FOR THE HUMAN GENOME
1111
“killer app will connect genetic variants to environmental, lifestyle,
dietary, and activity related factors, guiding both sick and healthy
people towards a fundamentally better quality of life..”
Source: Apple Healthcare, 2015
Source: Topol, 2014

12. PROBLEM SPACE IN HEALTHCARE
UNDERSTANDING &
RELATING MANY DATA
SETS

13. The New Era Of
Cognitive Computing and A.I.
13
• 1956-
Dartmouth AI
Conference
• Fast CPU/VPU
• Hierarchical
Algorithms
• Weak AI
• Strong AI (AGI)
• Deep
Learning
• Supervised
• Unsupervise
d

14. COGNITIVE
HEALTHCARE
CLINICAL, FITNESS
AND WELLNESS
OME
DIGITAL HEALTH
PLATFORM
AND DEEP LEARNING
™

15. WHAT A CONSUMER WANTS FOR HEALTHCARE
Plan
A
Plan
B
✔ ✔ ✔ ✔ ✔ ✔
Content Needs
SHORT-TERM LONG-TERMMID-TERM
Understand
my needs
Select my Doc
or Benefit
Manage and
Improve My Health
Get Health and
Wellness Services
Get Health and
Wellness Goods
Seek Information
and Support

16. Trusting Health Apps
“In 2016, Users
Will Trust Health
Apps More Than
Their Doctors...”
(DEC 31, 2015 FORBES)
79 percent (%) of Americans said they would be
willing to use a wearable device to manage their
health

17. Other
Tools & Medication
Pregnancy
Sleep & Medication
Women's Health
Exercise
Weight Loss
8 Million
10.5 Million
26.5 Million
50 Million
18 Million
6 Million
7.5 Million
OF mHEALTH APPS (2014)
RISING POPULARITY
Source: Forbes 2015
US User #’s

18. APP Stores - #1 Distribution Channel
APP stores number one distribution
channel for mHealth apps
- MAW Feb 2016
“Distribution through other channels, such as via
doctors, hospitals, or pharmacies are
increasingly seen to be weaker channels through
which to distribute a successful app solution.”

19. 3.4 BILLION PEOPLE WORLDWIDE
WILL OWN A SMARTPHONE
WILL USE HEALTH APPS
MARKET IN 2017
mHEALTH
THE TOTAL GLOBAL mHEALTH
MARKET WILL REACH $26 BILLION
½

20. What is OME?
Ome™ is the world’s first precision
health and wellness mobile
application using artificial
intelligence (A.I.) and genetics to
help provide consumers with
precision information.

21. What is “cool” about AI/Cognitive
and Healthcare?
• Biodata and NLP allows users to ask questions in everyday
language that is translated into a Query to search for correct
responses
• OME gets more accurate the more it is used; Dynamic
Content
• We can accommodate client specific content (EHR,
Genetic/WGS test, health survey, insurance); PHI is personal
(HIPPA, etc.)
• Useful for many industries: Hospitals, Automotive, HR
groups, Energy, Government, Telco, Hotels/Hospitality, etc
Employee safety, greater productivity, less
absenteeism, "precision" healthcare

22. Creating
PERSONALIZED RESULTS
22

23. ENABLES YOU TO
TAKE CHARGE

24. GATHERING AND CURATION
OME™ - USE INFORMATION
QUESTION:
WHAT SHOULD I DO FOR MY
WORKOUT TODAY?
ANSWER:
YOU COULD GO FOR 2 MILE RUN IN CENTRAL PARK, TAKE 100MGS
ADVIL AND DRINK ONE COFFEE FIRST (NO SUGAR), because of your
CYP1A2 gene you are a slow metabolizer of caffeine, AND BE CLOSER TO
EARNING 100 POINTS FROM VITALITY HEALTHCARE. BRING YOUR
FITBIT. WHY DON’T YOU INVITE RUNNERDUDE100?

25. REAL TIME
EVENT ACTIONABILTY
OME™: IF YOU RUN 2 MILES TODAY YOU
CAN ENJOY DINNER AT PAIZON’S
MEDITERRANEAN, NEAR YOU NOW, AS
PART OF YOUR DIET PLAN.

31. The Future
PATHWAY OME
The Pathway OME™ Mobile App
Healthcare Simplified
www.pathway.com
31
Michael Nova M.D.
Chief Innovation Officer
Pathway Genomics
Michael@Pathway.com