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1. Plant Derived
Vaccines
PRESENTATION BY
PRIMARY INFORMATION
SERVICES
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2. A new and exciting
possibility is the production
of vaccine antigens in
genetically modified plants
which can then be extracted
and purified by
conventional methods. Such
vaccines could either be
eaten or applied to mucosal
surfaces.

3. Plant-derived vaccines
have several advantages.
They can be produced
cheaply in very high
amounts, carrier plants
such as potatoes and corn
are readily accepted by
patients and antigens
derived from them are
stable and can be stored
for long periods of time.
The likelihood that
contamination by a plant
virus would have an
adverse effect on humans
is almost negligible.

4. There are several technical
challenges concerning plant-
derived vaccines that must be
resolved before they can enter
wide-scale use and the regulatory
requirements for this novel class of
vaccines must be established. In
addition, public acceptance of the
new technology must be ensured. As
the development of plant-derived
vaccines matures, WHO will
continue to serve as a forum for the
international harmonization of
requirements.

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