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MANAGEMENT OF A BURN PATIENT
Dr sumer yadav
Aim of burn care
• Rescue
• Resuscitate
• Refer
• Resurface
• Rehabilitate
• Reconstruct
• Review
Principles of BURN MANAGEMENT
• Airway management-quick and appropriate
• Prompt and accurate fluid resuscitation
• Removal of dead burnt skin and replacement
with homograft(cadaveric skin from SKIN BANK)
or biologic skin substitutes
• Appropriate adequate nutrition
• Good chest PT
• Replacement of homograft with autograft or
cultured skin(cultured keratinocytes)
Which burn patients need
HOSPITALISATION?
• We go by the AMERICAN BURN ASSOCIATION
GUIDELINES
Management of the Patient With
a Burn Injury
6
• Burn care must be planned according to the burn depth
and local response, the extent of the injury, and the
presence of a systemic response.
• Burn care then proceeds through three phases:
– Emergent/resuscitative phase (on-the-scene care),
– Acute/intermediate phase, and
– Rehabilitation phase.
• Although priorities exist for each of the phases, the
phases overlap, and assessment and management of
specific problems and complications are not limited to
these phases but take place throughout burn care.
Table: phases of burn care
7
Phase Duration Priorities
Emergent or
immediate
resuscitative
From onset of injury to
completion
of fluid resuscitation
• First aid
• Prevention of shock
• Prevention of respiratory distress
• Detection and treatment of concomitant
injuries
• Wound assessment and initial care
Acute From beginning of diuresis
to near
completion of wound
closure
• Wound care and closure
• Prevention or treatment of
complications, including infection
• Nutritional support
Rehabilitati
on
From major wound closure
to return
to individual’s optimal level
of physical
and psychosocial
adjustment
• Prevention of scars and contractures
• Physical, occupational, and vocational
rehabilitation
• Functional and cosmetic reconstruction
• Psychosocial counseling
INTENSIVE BURN CARE UNIT(IBCU)
INTENSIVE BURNS CARE UNIT(IBCU)
LEVELS OF ICU CARE
• Level - I – provides
monitoring, observation
and short term
ventilation.
• Level - II – Provides
Observation,
Monitoring & Long
Term Ventilation With
Resident Doctors.
• Level - III – provides
all aspects of intensive
care including invasive
haemo dynamic
monitoring & dialysis.
History
• Type of burn:
– Flame (open flame, closed space)
– Chemical (type of chemical)
– Scald (type of liquid)
– Electrical (voltage, arcing/flame, contact time)
A: Airway
History & Physical: Inhalational injury
• Fire in a closed space.
• Full-thickness/ deep
chemical burns to face,
neck.
• Singed nasal hair.
• Carbonaceous sputum.
• Carbonaceous particles in
oropharynx.
A: Airway
• Burned airways swell
rapidly.
• Intubate patient as
early as possible
before airway
swelling.
A: Airway
• Indications for intubation:
– Oropharyngeal erythema/ swelling on direct
visualization.
– Change in voice, harsh cough.
– Stridor.
– Dyspnea, tachypnea.
B: Breathing
• Circumferential full-
thickness burns may impair
ventilation.
• Blast injuries can cause
pneumothorax, lung
contusions.
• Noxious chemical (plastic)
can cause a chemical
pneumonitis.
• Carbon monoxide poisoning
(if COHb > 15-40%
ventilate).
C: Circulation
• BP, HR, color of unburnt skin
• 2 large bore I.V.s in unburnt skin
• Draw bloodwork.
• Insert urinary catheter.
• Insert nasogastric tube, if necessary
• Doppler exam of circumferentially burnt
extremities
ASSESSMENT OF BURNS
• TBSA(Total body surface area)
• Decides fluid requirements and nutritional needs
• Wallace’s rule of nines
• Lund and Browder chart
• DEPTH
• Dictates local and surgical wound management
Management of fluid loss and shock
Fluid Replacement Therapy:
• The total volume and rate of intravenous fluid
replacement are gauged by the patient’s
response.
• The adequacy of fluid resuscitation is determined
by:
–Output totals of 30 to 50 mL/hour
–systolic blood pressure exceeding 100 mm Hg
and/or
19
Assessing adequacy of
resuscitation
• Peripheral blood pressure: may
be difficult to obtain – often
misleading
• Urine Output: Best indicator
unless ARF occurs
• CVP: Better indicator of fluid
status
• Heart rate: Valuable in early
post burn period – should be
around 120/min.
• > HR indicates need for > fluids
or pain control
• Invasive cardiac monitoring:
Indicated in a minority of
patients (elderly or pre-existing
cardiac disease)
Conditions Leading to Burn Shock
21
Management of fluid loss and shock
Fluid Requirements:
• The projected fluid requirements for the first 24
hours are calculated by the clinician based on the
extent of the burn injury.
• Some combination of fluid categories may be
used:
–Colloids (whole blood, plasma, and plasma
expanders) and
– Crystalloids/electrolytes (physiologic sodium
chloride or lactated Ringer’s solution).
22
Management of fluid loss and shock
Fluid Requirements:
• Adequate fluid resuscitation results in slightly
decreased blood volume levels during the
first 24 post-burn hours and restores plasma
levels to normal by the end of 48 hours.
• Oral resuscitation can be successful in adults
with less than 20% TBSA and children with
less than 10% to 15% TBSA.
23
Fluid resuscitation
• Lactated Ringers - preferred solution
• Contains Na+ - restoration of Na+ loss is
essential
• Free of glucose – high levels of circulating
stress hormones may cause glucose
intolerance
Guidelines and Formulas for Fluid
Replacement in Burn Patients
Consensus Formula
• Lactated Ringer’s solution (or other balanced
saline solution): 2–4 mL× kg body weight × %
total body surface area (TBSA) burned.
• Half to be given in first 8 hours; remaining half to
be given over next 16 hours.
25
Guidelines and Formulas for Fluid
Replacement in Burn Patients
• The following example illustrates use of the
formula in a management of a 70-kg patient
with a 50% TBSA burn:
• Steps
–1, Consensus formula: 2 to 4 mL/kg/% TBSA
–2, 2 × 70 × 50 = 7,000 mL/24 hours
–3, Plan to administer: First 8 hours = 3,500
mL, or 437 mL/ hour; next 16 hours = 3,500
mL, or 219 mL/hour
26
Guidelines and Formulas for Fluid Replacement in Burn Patients
Evans Formula
• 1. Colloids: 1 mL × kg body weight × % TBSA burned
• 2. Electrolytes (saline): 1 mL × body weight × % TBSA burned
• 3. Glucose (5% in water): 2,000 mL for insensible loss
• Day 1: Half to be given in first 8 hours; remaining half over next 16
hours
• Day 2: Half of previous day’s colloids and electrolytes; all of
insensible fluid replacement
• Maximum of 10,000 mL over 24 hours. Second- and third-degree
• (partial- and full-thickness) burns exceeding 50% TBSA are calculated
• on the basis of 50% TBSA.
27
Guidelines and Formulas for Fluid
Replacement in Burn Patients
Brooke Army Formula
• 1. Colloids: 0.5 mL × kg body weight × % TBSA
burned
• 2. Electrolytes (lactated Ringer’s solution): 1.5 mL
× kg body weight × % TBSA burned
• 3. Glucose (5% in water): 2,000 mL for insensible
loss
28
Guidelines and Formulas for Fluid
Replacement in Burn Patients
Parkland/Baxter Formula
• Lactated Ringer’s solution: 4 mL × kg body
weight × % TBSA burned
• Day 1: Half to be given in first 8 hours; half to
be given over next16 hours
• Day 2: Varies. Colloid is added.
29
Guidelines and Formulas for Fluid
Replacement in Burn Patients
Hypertonic Saline Solution
• Concentrated solutions of sodium chloride (NaCl) and
lactate with concentration of 250–300 mEq of sodium
per liter, administered at a rate sufficient to maintain a
desired volume of urinary output.
• Do not increase the infusion rate during the first 8 post
burn hours.
• Serum sodium levels must be monitored closely.
• Goal: Increase serum sodium level and osmolality to
reduce edema and prevent pulmonary complications.
30
Pediatric Fluid resuscitation
• Use Parkland formula + MAINTENANCE fluid
• For maintenance fluid, hourly rate of
4 mL/kg for first 10 kg of body weight plus
2 mL/kg for second 10 kg of body weight plus
1 mL/kg for >20 kg of body weight
• End point: urine output of 1.0-1.5 mL/kg/hr
• Maintenance fluid given is D5W/ iso-p (child’s liver
not fully matured- limited glycogen stores).
Fluid resuscitation
• Need to replace losses to maintain homeostasis.
• Formulas are ONLY GUIDELINES.
• Monitor physiologic parameters.
• Maintain adequate tissue perfusion to prevent
increase in depth of burn.
• Too little fluid Hypotension renal failure, etc.► ►
• Too much fluid Edema Tissue hypoxia► ►
Fluid resuscitation
• Fluid resuscitation should be started when
– >15% TBSA burns in an adult
– >10% TBSA in children and elderly
• First 8-12 hrs: intravascular volume shifts to
interstitial space.
• Fast fluid boluses are of no benefit.
• Colloids: Questionable in first 24 hrs (capillary
leakage)
Fluid Management
• Start with RL in adults and Isolyte P in
children
• After 24 hrs start DNS
• If not adequate urine output in 12 hrs start
colloids FFP
• More fluids required in Electric Burns and
Inhalation Injury
• Always central line (sometimes even thro
burnt tissue) for initial resuscitation
Electrical injury resuscitation
• Fluid needs greater
• 9 mL x TBSA burn (%) x body weight (kg) in
first 24 hrs
• If myoglobinuria, may require bicarbonate
infusion to alkalinize urine to pH > 8
• End point: urine output of 1.5-2 mL/kg/hr
Electrolyte Abnormalities
• HYPOKALEMIA- seen more often than
Hyperkalemia
• Commonest cause of non infective paralytic
ileus
• Serum K <3mEq/l KCl at 10mEq/hr
• Serum K <2mEq/l KCl at 40mEq/hr
• Daily Ser Electrolytes in first 3 days
Electrolyte Abnormalities
• HYPOCALCEMIA-most commonly due to
Hypoalbuminemia
• Lowering of Ser Albumin by 1g/ml lowers Ser
Calcium by 1g/ml
• Alkalosis also lowers Ser Ca by increasing
protein binding
• Correction required only if symptomatic
• Associated Hypomagnesemia needs
simultaneous correction to prevent tetany
and arrhythmias
Reducing the HYPERMETABOLIC
RESPONSE
• Temperature regulation
• Nutrition
• Pharamacological manipulation-Propranolol
40 mg BD and Oxandrolone 5mg BD
• Early excision and homografting
Effects of hypothermia
• Hypothermia may lead to acidosis/coagulopathy
• Hypothermia causes peripheral vasoconstriction and
impairs oxygen delivery to the tissues
• Metabolism changes from aerobic to anaerobic
serum lactate serum pH
Prevention of hypothermia
• Cover patients with a dry
sheet – keep head covered
• Pre-warm trauma room
• Administer warmed IV
solutions
• Avoid application of saline-
soaked dressings
• Avoid prolonged irrigation
• Remove wet / bloody
clothing and sheets
• Paralytics – unable to shiver
and generate heat
• Avoid application of
antimicrobial creams
• Continual monitoring of
core temperature via foley
or SCG temperature probe
Role of LMWH
• Incidence of Deep Vein Thrombosis is
significant enough to warrant routine use of
LMWH
• Incidence of Pulmonary embolism is reduced
significantly
• Daltaparin or Enoxiparin
• Fragmin or Clexane
• This is stopped once patient is mobile
INTRAABDOMINAL HYPERTENSION
and
INTRAABDOMINAL
COMPARTMENT SYDROME
Abd compartment syndrome-
LAPAROTOMY
Nutrition
• Aggressive nutritional support to
counterbalance the effect of
Hypermetabolism and Protein catabolism
following Burns
• ENTERAL feeding is preferred over
PARENTERAL feeding
Nutritional support
• Calorie : Nitrogen = 100 : 1
• Protein requirement
– Adult: 2g/ kg/ day
– Child: 3g/ kg/ day
• Fat emulsion
– 4g/ kg/ day max.
• Carbohydrate (glucose)
– 6.2mg/ kg/ min. max.
Nutritional support
• Burns patient is hypercatabolic – up to 150-
200% above baseline.
• Nutrition needed for burns >20% TBSA.
• Curreri formula
–Adult: 25kcal/kg/day + 40kcal/ % TBSA burn
–Child: 60kcal/kg/day + 35kcal/ % TBSA burn
NUTRITION
• Burn patient caloric requirement 3000-
5000calories per day
• Early feeding
• Nasogastric tube No 10
• Hourly tube feeding
Butter milk diet 1cal/cc
Eggs 4
Bananas 4
Sugar 4Tbs
Curd 1 litre
BUTTERMILK DIET(BMD)
• Eggs- 4 /Protein
powders(Whey protein
or Soya protein)
• Bananas- 4
• Sugar- 4 Tbsf
• Curds (Yoghurt) -1000cc
• Mixed with water to
1600cc
Antibiotic Protocol
• FRESH BURN
• Start with a 3rd
gen Cephalosporin with an
aminoglycoside
• INFECTED OLD BURN
• Start with a semisynthetic Penecillin like Pipra
and Tazobactum or a Carbapenem
• LATER go by wound swabs culture and sensitivity
Pain Management
• Continuous infusion round the clock of
Tramadol 100mg
Ketamine 100mg
Midazolam 10mg
• In a 50cc syringe in a syringe pump
• Resting Pain-At 4-6cc per hour to start and then
titrate with pain response
• Procedural Pain-During dressing 30-40cc per hour
and titrate
Chest Physiotherapy
Limb Physiotherapy
Initial burn wound management
• Early transfer to burn centre (within first 24 hours):
– Remove smoldering, non-adherent clothes.
– No debridement or topical agents needed.
– Clean, dry sheets,
– Wet dressing cause heat loss.
• If transfer is delayed > 24 hours:
– Unroof blisters >2 cm, cleanse with chlorhexidine
– Silver sulfadiazine cream OD or Povidone Iodine solution
and Vaseline gauze
Procedures
• Tracheostomy
• Central line
insertion
• Escharotomy
• Debridement.
Dr. Sunil Keswani, National
Burns Centre, www.burns-
india.com,
Burn wound management
• Circumferential
extremity burns:
– Edema under eschar
– Remove all rings, jewelry
– Elevate, active motion
– Check skin color,
sensation, capillary refill,
Doppler pulses q1h
– Rule out hypotension,
arterial injury
Burn wound management
• Bedside escharotomy
• 3rd degree burns
insensate
• Use electrocautery
• Mid-medial or mid-
lateral, across joints
• Recheck pulses - may
have to do opposite side
of limb
Esharotomy-LINES OF INCISION
Fasciotomy
• Pain
• Pallor-look at capillary refill
time-if less than 2 secs-
VENOUS OBSTRUCTION and
if more than 5 secs –
ARTERIAL OBSTRUCTION
• Pressure
• Pulselessnes
• Paresthesia
• Paralysis
• Poikilothermia
• Progression
• Compartmental
pressures above
25mm Hg warrant
a FASCIOTOMY
• There are devices
to measure this
pressure
• Or use DOPPLER to
decide
Fasciotomy In Burns
Fasciotomy-methodology
Leg-FASCIAL COMPARTMENTS
Burn wound management
Specific anatomical areas:
Face - watch for airway compromise
Eyes - fluorescein exam, copious irrigation,
antibiotic ointment,mydriatics
Ears - external canal, TM (children, perf in blast
injury)
Genitalia, perineum - insert Foley to stent urethra
 treat scrotal edema conservatively
 diverting colostomy NOT automatically indicated in perineal
burns
SURGICAL TECHNIQUES-ACUTE BURNS
EARLY EXCISION
Tangential excision and grafting-within first
72 hrs
Cadaveric skin from SKIN BANK
DELAYED EXCISION
Fascial excision and grafting-after 72hrs
Cadaveric skin from SKIN BANK
Early excision Vs Delayed excision
• Always early excision if patient comes early
enough and facilities exist
• Early enough is upto 72 hrs postburn
• Early excision decreases the chances of Sepsis
and facilitates early moblisation and better
and more predictable functional recovery.
• Delayed excision is generally at 3 weeks or
later
Early Excision
• Within the first 3-5days
• After 5 days chances of Sepsis higher and
bleeding more
• 15% of BSA is excised at a time
• Coverage of excised area by Meshed
Homograft is mandatory
Order of excision
• Areas easy and quick to excise: trunk and
legs
• Joints and throats
• Hands and face
Early Excision
• Blood Loss
– Clear pre-operative plan
– Excision prior to wound hyperemia
– Elevation of extremities
– Tourniquet control
– Dilute Epinephrine tumescent fluid
– Epinephrine soaked sponges
Early Excision
• Procedure (En Bloc)
– For deeper burns
– Skin and fat excised in one session
– Less time consuming
– Excision down to the natural cleavage plane
– Down to fat or Fascia
Meshed graft Vs Meek Micrografting
Vs Sheet Graft
• Acute burns always meshed or meek
micrografting for better takes
• Reconstructive procedures like overgrafting
and release of contractures always sheet
grafting for better cosmesis
• Meek micrografting gives wider coverage and
more predictable takes than mesh grafting but
more expensive
Dermatome with blade
DERMATOME-HARVESTING GRAFT
Fascial excision
Integra and ACTICOAT
Case -2 skin grafting
Cultured autologous keratinocytes
• Grown in vitro and then applied to wounds
• Take of cultured epithelial autografts depends
on the wound bed
• Expensive
• Skilled labour and quality control,
• 3–5 weeks to produce 1.8m2 confluent sheets
of cells from a 2 cm2 biopsy
• Fragile sheets
• Blistering, infection, and contractures.
Wound Closure
• Suggested Clinical Indications for CAE
– burn injuries >90% broad
– 70-90% more limited
– <70% no clear indication
PITFALLS IN BURN MANAGEMENT
• Early tracheostomy
• Prompt adequate resuscitation
• Infection control practices
• Pain relief
• Early enteral nutrition
• Early mobilisation and Intensive chest PT
• DVT prophylaxis
PITFALLS IN BURN MANAGEMENT
• Escharotomy
• Fasciotomy
• Early excision and use of banked skin
• Fascial excison and use of banked skin or
autografts
• Early rehabilitation-
physical,social,psychological
TEAM APPROACH TO BURNS
• Plastic Surgeon
• General Surgeon
• Ophthalomologist
• ENT surgeon
• Intensivist
• Nephrologist
• Anesthesiologist
• Cardiologist
• Psychiatrist
Nurses
Microbiologist
Physiotherapist
Occupational therapist
Psychological Counsellor
Social Worker
Dietitian
Prevention team
thanks

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scar management - nonsurgicalscar management - nonsurgical
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common congenital deformities of handcommon congenital deformities of hand
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gastrocnemius flap
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fractures of hand bonesfractures of hand bones
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management of a burn patient

  • 1. MANAGEMENT OF A BURN PATIENT Dr sumer yadav
  • 2. Aim of burn care • Rescue • Resuscitate • Refer • Resurface • Rehabilitate • Reconstruct • Review
  • 3. Principles of BURN MANAGEMENT • Airway management-quick and appropriate • Prompt and accurate fluid resuscitation • Removal of dead burnt skin and replacement with homograft(cadaveric skin from SKIN BANK) or biologic skin substitutes • Appropriate adequate nutrition • Good chest PT • Replacement of homograft with autograft or cultured skin(cultured keratinocytes)
  • 4. Which burn patients need HOSPITALISATION? • We go by the AMERICAN BURN ASSOCIATION GUIDELINES
  • 5.
  • 6. Management of the Patient With a Burn Injury 6 • Burn care must be planned according to the burn depth and local response, the extent of the injury, and the presence of a systemic response. • Burn care then proceeds through three phases: – Emergent/resuscitative phase (on-the-scene care), – Acute/intermediate phase, and – Rehabilitation phase. • Although priorities exist for each of the phases, the phases overlap, and assessment and management of specific problems and complications are not limited to these phases but take place throughout burn care.
  • 7. Table: phases of burn care 7 Phase Duration Priorities Emergent or immediate resuscitative From onset of injury to completion of fluid resuscitation • First aid • Prevention of shock • Prevention of respiratory distress • Detection and treatment of concomitant injuries • Wound assessment and initial care Acute From beginning of diuresis to near completion of wound closure • Wound care and closure • Prevention or treatment of complications, including infection • Nutritional support Rehabilitati on From major wound closure to return to individual’s optimal level of physical and psychosocial adjustment • Prevention of scars and contractures • Physical, occupational, and vocational rehabilitation • Functional and cosmetic reconstruction • Psychosocial counseling
  • 8. INTENSIVE BURN CARE UNIT(IBCU)
  • 9. INTENSIVE BURNS CARE UNIT(IBCU)
  • 10. LEVELS OF ICU CARE • Level - I – provides monitoring, observation and short term ventilation. • Level - II – Provides Observation, Monitoring & Long Term Ventilation With Resident Doctors. • Level - III – provides all aspects of intensive care including invasive haemo dynamic monitoring & dialysis.
  • 11. History • Type of burn: – Flame (open flame, closed space) – Chemical (type of chemical) – Scald (type of liquid) – Electrical (voltage, arcing/flame, contact time)
  • 12.
  • 13. A: Airway History & Physical: Inhalational injury • Fire in a closed space. • Full-thickness/ deep chemical burns to face, neck. • Singed nasal hair. • Carbonaceous sputum. • Carbonaceous particles in oropharynx.
  • 14. A: Airway • Burned airways swell rapidly. • Intubate patient as early as possible before airway swelling.
  • 15. A: Airway • Indications for intubation: – Oropharyngeal erythema/ swelling on direct visualization. – Change in voice, harsh cough. – Stridor. – Dyspnea, tachypnea.
  • 16. B: Breathing • Circumferential full- thickness burns may impair ventilation. • Blast injuries can cause pneumothorax, lung contusions. • Noxious chemical (plastic) can cause a chemical pneumonitis. • Carbon monoxide poisoning (if COHb > 15-40% ventilate).
  • 17. C: Circulation • BP, HR, color of unburnt skin • 2 large bore I.V.s in unburnt skin • Draw bloodwork. • Insert urinary catheter. • Insert nasogastric tube, if necessary • Doppler exam of circumferentially burnt extremities
  • 18. ASSESSMENT OF BURNS • TBSA(Total body surface area) • Decides fluid requirements and nutritional needs • Wallace’s rule of nines • Lund and Browder chart • DEPTH • Dictates local and surgical wound management
  • 19. Management of fluid loss and shock Fluid Replacement Therapy: • The total volume and rate of intravenous fluid replacement are gauged by the patient’s response. • The adequacy of fluid resuscitation is determined by: –Output totals of 30 to 50 mL/hour –systolic blood pressure exceeding 100 mm Hg and/or 19
  • 20. Assessing adequacy of resuscitation • Peripheral blood pressure: may be difficult to obtain – often misleading • Urine Output: Best indicator unless ARF occurs • CVP: Better indicator of fluid status • Heart rate: Valuable in early post burn period – should be around 120/min. • > HR indicates need for > fluids or pain control • Invasive cardiac monitoring: Indicated in a minority of patients (elderly or pre-existing cardiac disease)
  • 21. Conditions Leading to Burn Shock 21
  • 22. Management of fluid loss and shock Fluid Requirements: • The projected fluid requirements for the first 24 hours are calculated by the clinician based on the extent of the burn injury. • Some combination of fluid categories may be used: –Colloids (whole blood, plasma, and plasma expanders) and – Crystalloids/electrolytes (physiologic sodium chloride or lactated Ringer’s solution). 22
  • 23. Management of fluid loss and shock Fluid Requirements: • Adequate fluid resuscitation results in slightly decreased blood volume levels during the first 24 post-burn hours and restores plasma levels to normal by the end of 48 hours. • Oral resuscitation can be successful in adults with less than 20% TBSA and children with less than 10% to 15% TBSA. 23
  • 24. Fluid resuscitation • Lactated Ringers - preferred solution • Contains Na+ - restoration of Na+ loss is essential • Free of glucose – high levels of circulating stress hormones may cause glucose intolerance
  • 25. Guidelines and Formulas for Fluid Replacement in Burn Patients Consensus Formula • Lactated Ringer’s solution (or other balanced saline solution): 2–4 mL× kg body weight × % total body surface area (TBSA) burned. • Half to be given in first 8 hours; remaining half to be given over next 16 hours. 25
  • 26. Guidelines and Formulas for Fluid Replacement in Burn Patients • The following example illustrates use of the formula in a management of a 70-kg patient with a 50% TBSA burn: • Steps –1, Consensus formula: 2 to 4 mL/kg/% TBSA –2, 2 × 70 × 50 = 7,000 mL/24 hours –3, Plan to administer: First 8 hours = 3,500 mL, or 437 mL/ hour; next 16 hours = 3,500 mL, or 219 mL/hour 26
  • 27. Guidelines and Formulas for Fluid Replacement in Burn Patients Evans Formula • 1. Colloids: 1 mL × kg body weight × % TBSA burned • 2. Electrolytes (saline): 1 mL × body weight × % TBSA burned • 3. Glucose (5% in water): 2,000 mL for insensible loss • Day 1: Half to be given in first 8 hours; remaining half over next 16 hours • Day 2: Half of previous day’s colloids and electrolytes; all of insensible fluid replacement • Maximum of 10,000 mL over 24 hours. Second- and third-degree • (partial- and full-thickness) burns exceeding 50% TBSA are calculated • on the basis of 50% TBSA. 27
  • 28. Guidelines and Formulas for Fluid Replacement in Burn Patients Brooke Army Formula • 1. Colloids: 0.5 mL × kg body weight × % TBSA burned • 2. Electrolytes (lactated Ringer’s solution): 1.5 mL × kg body weight × % TBSA burned • 3. Glucose (5% in water): 2,000 mL for insensible loss 28
  • 29. Guidelines and Formulas for Fluid Replacement in Burn Patients Parkland/Baxter Formula • Lactated Ringer’s solution: 4 mL × kg body weight × % TBSA burned • Day 1: Half to be given in first 8 hours; half to be given over next16 hours • Day 2: Varies. Colloid is added. 29
  • 30. Guidelines and Formulas for Fluid Replacement in Burn Patients Hypertonic Saline Solution • Concentrated solutions of sodium chloride (NaCl) and lactate with concentration of 250–300 mEq of sodium per liter, administered at a rate sufficient to maintain a desired volume of urinary output. • Do not increase the infusion rate during the first 8 post burn hours. • Serum sodium levels must be monitored closely. • Goal: Increase serum sodium level and osmolality to reduce edema and prevent pulmonary complications. 30
  • 31. Pediatric Fluid resuscitation • Use Parkland formula + MAINTENANCE fluid • For maintenance fluid, hourly rate of 4 mL/kg for first 10 kg of body weight plus 2 mL/kg for second 10 kg of body weight plus 1 mL/kg for >20 kg of body weight • End point: urine output of 1.0-1.5 mL/kg/hr • Maintenance fluid given is D5W/ iso-p (child’s liver not fully matured- limited glycogen stores).
  • 32. Fluid resuscitation • Need to replace losses to maintain homeostasis. • Formulas are ONLY GUIDELINES. • Monitor physiologic parameters. • Maintain adequate tissue perfusion to prevent increase in depth of burn. • Too little fluid Hypotension renal failure, etc.► ► • Too much fluid Edema Tissue hypoxia► ►
  • 33. Fluid resuscitation • Fluid resuscitation should be started when – >15% TBSA burns in an adult – >10% TBSA in children and elderly • First 8-12 hrs: intravascular volume shifts to interstitial space. • Fast fluid boluses are of no benefit. • Colloids: Questionable in first 24 hrs (capillary leakage)
  • 34. Fluid Management • Start with RL in adults and Isolyte P in children • After 24 hrs start DNS • If not adequate urine output in 12 hrs start colloids FFP • More fluids required in Electric Burns and Inhalation Injury • Always central line (sometimes even thro burnt tissue) for initial resuscitation
  • 35.
  • 36. Electrical injury resuscitation • Fluid needs greater • 9 mL x TBSA burn (%) x body weight (kg) in first 24 hrs • If myoglobinuria, may require bicarbonate infusion to alkalinize urine to pH > 8 • End point: urine output of 1.5-2 mL/kg/hr
  • 37. Electrolyte Abnormalities • HYPOKALEMIA- seen more often than Hyperkalemia • Commonest cause of non infective paralytic ileus • Serum K <3mEq/l KCl at 10mEq/hr • Serum K <2mEq/l KCl at 40mEq/hr • Daily Ser Electrolytes in first 3 days
  • 38. Electrolyte Abnormalities • HYPOCALCEMIA-most commonly due to Hypoalbuminemia • Lowering of Ser Albumin by 1g/ml lowers Ser Calcium by 1g/ml • Alkalosis also lowers Ser Ca by increasing protein binding • Correction required only if symptomatic • Associated Hypomagnesemia needs simultaneous correction to prevent tetany and arrhythmias
  • 39. Reducing the HYPERMETABOLIC RESPONSE • Temperature regulation • Nutrition • Pharamacological manipulation-Propranolol 40 mg BD and Oxandrolone 5mg BD • Early excision and homografting
  • 40. Effects of hypothermia • Hypothermia may lead to acidosis/coagulopathy • Hypothermia causes peripheral vasoconstriction and impairs oxygen delivery to the tissues • Metabolism changes from aerobic to anaerobic serum lactate serum pH
  • 41. Prevention of hypothermia • Cover patients with a dry sheet – keep head covered • Pre-warm trauma room • Administer warmed IV solutions • Avoid application of saline- soaked dressings • Avoid prolonged irrigation • Remove wet / bloody clothing and sheets • Paralytics – unable to shiver and generate heat • Avoid application of antimicrobial creams • Continual monitoring of core temperature via foley or SCG temperature probe
  • 42.
  • 43. Role of LMWH • Incidence of Deep Vein Thrombosis is significant enough to warrant routine use of LMWH • Incidence of Pulmonary embolism is reduced significantly • Daltaparin or Enoxiparin • Fragmin or Clexane • This is stopped once patient is mobile
  • 45.
  • 46.
  • 47.
  • 48.
  • 50. Nutrition • Aggressive nutritional support to counterbalance the effect of Hypermetabolism and Protein catabolism following Burns • ENTERAL feeding is preferred over PARENTERAL feeding
  • 51. Nutritional support • Calorie : Nitrogen = 100 : 1 • Protein requirement – Adult: 2g/ kg/ day – Child: 3g/ kg/ day • Fat emulsion – 4g/ kg/ day max. • Carbohydrate (glucose) – 6.2mg/ kg/ min. max.
  • 52. Nutritional support • Burns patient is hypercatabolic – up to 150- 200% above baseline. • Nutrition needed for burns >20% TBSA. • Curreri formula –Adult: 25kcal/kg/day + 40kcal/ % TBSA burn –Child: 60kcal/kg/day + 35kcal/ % TBSA burn
  • 53. NUTRITION • Burn patient caloric requirement 3000- 5000calories per day • Early feeding • Nasogastric tube No 10 • Hourly tube feeding Butter milk diet 1cal/cc Eggs 4 Bananas 4 Sugar 4Tbs Curd 1 litre
  • 54. BUTTERMILK DIET(BMD) • Eggs- 4 /Protein powders(Whey protein or Soya protein) • Bananas- 4 • Sugar- 4 Tbsf • Curds (Yoghurt) -1000cc • Mixed with water to 1600cc
  • 55. Antibiotic Protocol • FRESH BURN • Start with a 3rd gen Cephalosporin with an aminoglycoside • INFECTED OLD BURN • Start with a semisynthetic Penecillin like Pipra and Tazobactum or a Carbapenem • LATER go by wound swabs culture and sensitivity
  • 56. Pain Management • Continuous infusion round the clock of Tramadol 100mg Ketamine 100mg Midazolam 10mg • In a 50cc syringe in a syringe pump • Resting Pain-At 4-6cc per hour to start and then titrate with pain response • Procedural Pain-During dressing 30-40cc per hour and titrate
  • 59. Initial burn wound management • Early transfer to burn centre (within first 24 hours): – Remove smoldering, non-adherent clothes. – No debridement or topical agents needed. – Clean, dry sheets, – Wet dressing cause heat loss. • If transfer is delayed > 24 hours: – Unroof blisters >2 cm, cleanse with chlorhexidine – Silver sulfadiazine cream OD or Povidone Iodine solution and Vaseline gauze
  • 60. Procedures • Tracheostomy • Central line insertion • Escharotomy • Debridement. Dr. Sunil Keswani, National Burns Centre, www.burns- india.com,
  • 61. Burn wound management • Circumferential extremity burns: – Edema under eschar – Remove all rings, jewelry – Elevate, active motion – Check skin color, sensation, capillary refill, Doppler pulses q1h – Rule out hypotension, arterial injury
  • 62. Burn wound management • Bedside escharotomy • 3rd degree burns insensate • Use electrocautery • Mid-medial or mid- lateral, across joints • Recheck pulses - may have to do opposite side of limb
  • 64. Fasciotomy • Pain • Pallor-look at capillary refill time-if less than 2 secs- VENOUS OBSTRUCTION and if more than 5 secs – ARTERIAL OBSTRUCTION • Pressure • Pulselessnes • Paresthesia • Paralysis • Poikilothermia • Progression • Compartmental pressures above 25mm Hg warrant a FASCIOTOMY • There are devices to measure this pressure • Or use DOPPLER to decide
  • 68.
  • 69. Burn wound management Specific anatomical areas: Face - watch for airway compromise Eyes - fluorescein exam, copious irrigation, antibiotic ointment,mydriatics Ears - external canal, TM (children, perf in blast injury) Genitalia, perineum - insert Foley to stent urethra  treat scrotal edema conservatively  diverting colostomy NOT automatically indicated in perineal burns
  • 70.
  • 71. SURGICAL TECHNIQUES-ACUTE BURNS EARLY EXCISION Tangential excision and grafting-within first 72 hrs Cadaveric skin from SKIN BANK DELAYED EXCISION Fascial excision and grafting-after 72hrs Cadaveric skin from SKIN BANK
  • 72. Early excision Vs Delayed excision • Always early excision if patient comes early enough and facilities exist • Early enough is upto 72 hrs postburn • Early excision decreases the chances of Sepsis and facilitates early moblisation and better and more predictable functional recovery. • Delayed excision is generally at 3 weeks or later
  • 73. Early Excision • Within the first 3-5days • After 5 days chances of Sepsis higher and bleeding more • 15% of BSA is excised at a time • Coverage of excised area by Meshed Homograft is mandatory
  • 74. Order of excision • Areas easy and quick to excise: trunk and legs • Joints and throats • Hands and face
  • 75. Early Excision • Blood Loss – Clear pre-operative plan – Excision prior to wound hyperemia – Elevation of extremities – Tourniquet control – Dilute Epinephrine tumescent fluid – Epinephrine soaked sponges
  • 76. Early Excision • Procedure (En Bloc) – For deeper burns – Skin and fat excised in one session – Less time consuming – Excision down to the natural cleavage plane – Down to fat or Fascia
  • 77. Meshed graft Vs Meek Micrografting Vs Sheet Graft • Acute burns always meshed or meek micrografting for better takes • Reconstructive procedures like overgrafting and release of contractures always sheet grafting for better cosmesis • Meek micrografting gives wider coverage and more predictable takes than mesh grafting but more expensive
  • 82. Case -2 skin grafting
  • 83.
  • 84.
  • 85.
  • 86. Cultured autologous keratinocytes • Grown in vitro and then applied to wounds • Take of cultured epithelial autografts depends on the wound bed • Expensive • Skilled labour and quality control, • 3–5 weeks to produce 1.8m2 confluent sheets of cells from a 2 cm2 biopsy • Fragile sheets • Blistering, infection, and contractures.
  • 87. Wound Closure • Suggested Clinical Indications for CAE – burn injuries >90% broad – 70-90% more limited – <70% no clear indication
  • 88. PITFALLS IN BURN MANAGEMENT • Early tracheostomy • Prompt adequate resuscitation • Infection control practices • Pain relief • Early enteral nutrition • Early mobilisation and Intensive chest PT • DVT prophylaxis
  • 89. PITFALLS IN BURN MANAGEMENT • Escharotomy • Fasciotomy • Early excision and use of banked skin • Fascial excison and use of banked skin or autografts • Early rehabilitation- physical,social,psychological
  • 90. TEAM APPROACH TO BURNS • Plastic Surgeon • General Surgeon • Ophthalomologist • ENT surgeon • Intensivist • Nephrologist • Anesthesiologist • Cardiologist • Psychiatrist Nurses Microbiologist Physiotherapist Occupational therapist Psychological Counsellor Social Worker Dietitian Prevention team

Editor's Notes

  1. History is taken on admission prior to airway swelling.
  2. Assessment of adequacy of circulation includes evaluation of BP, HR, skin color of unburned skin. 2 large bore IV catheters are inserted in unburned skin to start fluid resuscitation. Insert a foley’s catheter &amp; NG tube. Blood is drawn at the time of IV insertion. Doppler examination for circulation in a circumferential extremity burn.
  3. Blood loss averages 134ml/% excised (1st day 100mL/%, 4th day 200mL/% Alternatively 8.8% of circulating blood volume is lost for each 1% excised. Tourniquet Esmarch bandage followed by pneumatic tourniquet 100mmHG above SBP Excise through grey/brown tissue to white glistening dermis or bright yellow fat. Apply grafts prior to letting down the tourniquet. Apply a pressure bandage Reports decreasing blood loss to 29mL/% excised BSA.
  4. Fat or Fascia No difference in graft take if fat is viable. Better contouring if fat is preserved.
  5. such asburns, chronic leg ulcers, giant pigmented naevi,epidermolysis bullosa and neonatal scalp necrosis separation from the tissue culture substrate using a proteolytic enzyme spontaneous blistering many months after grafting, increased susceptibility to infection, and contractures Bovine serum proteins act as growth promoters Delayed loss of graft initial take 64% declined to 47% at discharge for one study of 16 patients Cost $2000-34 000 pr percent of definitive wound closure at discharge. Blistering associated with high PGE2 and thromboxane levels suggesting an ongoing inflammatory response Effects of fibrin glues being evaluated with limited success Fibrin-glue suspensionSome success has been achieved by applying cells together with fibrin glue, in a suspensionof growth medium or using a membrane for delivery. Fibrin-glue sheets. Subconfluent cultured keratinocyteshave been grown on fibrin glue, and then transferred as asheet onto the wounds in three patients with excised fullthicknessburns. The fibrin was found to provide a satisfactorybarrier for 10 days,
  6. &amp;gt;90% burns limited donor sites can contribute to limited wound closure in a potentially y important manner 70-90-% clinical judgement depending on the donor sites e.g. face feet hands and genitalia are difficult to harvest &amp;lt;70% TBSA not usually necessary