Presentation of Persistent Company competencies in analytical instrumentation

1. www.persistentsys.com
Persistent’s expertise across
multiple Analytical Instruments
© 2012 Persistent Systems Ltd

2. Our Expertise
LC GC
FC
Our Expertise MS
across multiple
Instruments
NGS
PCR Bioinformatics
CE
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© 2012 Persistent Systems Ltd

3. Instrumentation Offerings
Performance & Computational Support
Product Development Data Analysis and visualization
• Performance optimizations in algorithms and
• Automate data acquisition / signal workflow tools • Comparative sequencing analysis for
processing systems SNP discovery and mutation detection
• Enablement of workflow on public/private cloud
• Automated testing to speed up • Fully integrated base calling, sequence
validation assembly, alignment, and sequence
comparison tools
• Research and clinical applications.
Instrument control software, primary • Reusable parsing framework and
,secondary and tertiary analysis components for biological data formats
applications • Implement visualization techniques for
• New application development or structured, unstructured and domain
customize widely used open source specific data sets
sequence analysis tools to support • Automatic data filtering and results
specific analysis reporting
• Data migration & integration services
• Integrate existing analysis tool to well
established visualization tools
Regulatory Compliance
Driver Development • Developing generic solutions to
satisfy guidelines mandated by
• Driver Portfolio management FDA
(Development, Maintenance and Bioinformatics
versioning) • Workflow automation by
interfacing with various
• Development of drivers, plug-in’s Chromatography Data Systems
and custom solutions
Bioinformatics • Develop applications that are
• Single shop of device drivers for 21CFR part
various instruments (Driver  Development of new algorithms for secondary 11, DQ, IQ, OQ, PV, GAMP, EU
Central) and tertiary analysis, implementation of GMP Annex
published algorithms 11, HL7, HIPAA, LOINC, ANSI
• Continuous Product Engineering
(CPE)  Performance tuning of prototype algorithms/ X12, ICD-9/10, DICOM
tools compliant
 Algorithm/Functional Testing • Usability engineered workflow
designs to ease on compliance
delivery
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• Deliver compliance services at
© 2012 Persistent Systems Ltd

4. Instrumentation (Chemistry) Expertise
Domain Experts
In-depth knowledge of high- Global Strategies
throughput laboratories needs Localization and globalization
of Software
Liquid Chromatography
Sample preparation, µ
HPLC, UV, DAD, fraction
collection
Software Design
Designing Ergonomic
software using Agile
methods
Bioinformatics
Gas Chromatography
Sample
preparation, headspace, SPME, Mass spectrometry
FID, ECD, TCD Strong expertise in Tuning, Mass
locking, MS/MS, MSn, complex
method edition
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© 2012 Persistent Systems Ltd

5. Instrumentation (Biology) Expertise
Real Time PCR NGS
• Developed software for multiple • Developed Instrument Control
generations of real time PCR Software,
instruments • Applications Framework for NGS
• Primary and secondary Data data analysis primary, secondary
collection and analysis software and tertiary data analysis,
• Application specific analysis software • Clinical application of NGS data
including pathogen detection, gene • Cloud hosted solutions
expression analysis software • Performance optimization of
algorithms and workflow tools
Flow Cytometer Capillary Electrophoresis
• Multicolor Flow Cytometry Instrument • End to end software development
• Flow Information System for Mining Bioinformatics • Primary and secondary data analysis
Of Flow Cytometry Data tools for fragment and Sequencing
• Rich tools for flow cytometer and data analysis.
application setup, data • Next generation platform for Assay
acquisition, and analysis that help integration for clinical use
streamline flow cytometry workflow.
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© 2012 Persistent Systems Ltd

6. Our Experience
Platforms Drivers Migration
• Diamir  Galaxie CDS • 100+ developed • CDS migration: Galaxie  OpenLAB
• Varian Next Gen. GC/MS CDS • Varian, Agilent, PE, Thermo, Waters, CTC, Kontron
• Agilent OpenLAB etc.
• Bruker CompassCDS • Native drivers, RC.net, ICF integration
• Agilent Cerity • Continuous Product Engineering (CPE)
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© 2012 Persistent Systems Ltd

7. Why Persistent?
Years of experience of Years of experience in
20+ producing chromatography
software for petro-chemical and
pharmaceutical companies
15+ Instrument Driver development
In-house Laboratory for Instrument Drivers
development & acceptance
testing 100+ developed
Strong cross-disciplinary Agile Practices for software
team – Computational development improving both
Scientists, Molecular customer satisfaction and time to
Biologists, Medicine, Bioinforma market
tics, Instrumentation Specialists
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© 2012 Persistent Systems Ltd

8. Contact Us
Sebastien RATTIER
R&D Manager for instrumentation
Persistent Systems France SAS
+33.4.76.53.35.87
sebastien.rattier@persistentsas.com
www.persistentsys.com
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© 2012 Persistent Systems Ltd © 2012 Persistent Systems Ltd