6. C O L L A G E N von Willebrand Factor fibrinogen endothelial cells Platelet Adhesion mediated by GP-Ib on platelet surface and vWF C O L L A G E N GP-Ib www.freelivedoctor.com
11. Coagulation Factors XII XI IX VIII VII X V I extrinsic pathway intrinsic pathway PT aPTT XIII Stable clot www.freelivedoctor.com II
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15. A A B B fibrinopeptide A & B D domain E domain Spontaneous aggregation fibrinogen fibrin monomer soluble fibrin polymer www.freelivedoctor.com E D D E D D E D D E D D E D D E D D E D D E D D B A A B E D D E thrombin Factor XIIIa
16. Stabilization of Fibrin Clot Thrombin Factor XII I Factor XIIIa soluble fibrin clot stabilized fibrin clot www.freelivedoctor.com E D D E D D E D D E D D E D D E D D E D E D E D D E D D E D D E D D E D D E D D E D E D
34. Plasmin Degradation of Fibrin Clot plasmin plasmin plasmin D-dimer E-fragment DED complex Fibrin Degradation Products www.freelivedoctor.com E D D E D D E D D E D D E D D E D D E D E D E D E D E D D D D E D D D D E
36. Procoagulant Platelets Factors Fibrinogen von Willebrand Factor Anticoagulant Antithrombin III Protein C Protein S Profibrinolytic Plasminogen tPA Fibrin Fragment D-dimer Antifibrinolytic PAI-1 Alpha-2 Antiplasmin clot RESOLUTION FORMATION www.freelivedoctor.com