Environmental Toxicity and the Effect on Health

Environmental Toxicityand the Effect on Health
Walter J. Crinnion, ND

Outline
What is our current toxic burden ?
How does it affect our health?
What do the patients and their doctors need to help with this huge problem?
Metametrix is the “go-to lab” for environmental medical testing

What is Our Current Toxic Burden?Are you toxic?

Better Living Through Chemistry
There are over 80,000 chemicals registered for use by the US EPA.
Over 3,800 of those are “high-use” chemicals.
Less than half of high-use chemicals have been assessed for toxic effect on humans.
Less than 9% have been assessed for toxic effects on children.

Environmental Working Group (EWG)Neonatal Toxicity Study
www.ewg.org/reports/bodyburden2/
10 babies born in US hospitals
287 chemical compounds identified in their cord blood
Average of 200 chemicals per infant

Toxins in the Cord Blood of US Newborns

EWG Adult Burden Study
9 persons
Including several international environmental activists
210 different chemicals
Average of 91 chemical toxins per person
www.ewg.org/reports/bodyburden1/

Bill Moyers’s Burden

Phthalates (plasticizers)in Urine(289 persons from CDC NHANES)
Two phthalates in all urine samples tested
Two more were found in over 75% of the samples as well

Xenobiotics in Meconium(in utero exposures)
Nicotine
Lowest but still detectable even in non-smokers
Two metabolites of organophosphate pesticides (DEP and DETP) were found in 19/20 and 20/20 samples
Mercury
In 6.4% of the maternal blood and 46.1% of the meconium

US Children’s Urine Studies
1,4-dichlorobenzene in 96% of Arkansas children
Chlorpyrifos in the urine of 93%, carbaryl in 45%, malathion in 33% in Minnesota
OP metabolites DMTP and DETP were found in 70-75%, at least one was present in 99% of samples in Seattle preschoolers
Only one child whose parents fed them organic food was clear of pesticides in the urine

The Weight…What we are all carrying
OCDD 9. Ethylphenol
HpCDD 10. DDE/T
HxCDD 11. PCBs
PeCDD 12. Phthalates
Styrene 13. Chlordanes
Dichlorbenzene 14. OP pesticides
Xylene 15. Pb, Hg, Cd, As, etc.
Parabens 16. PAHs

?
The Question About Human Toxic Burden
NOT — IF you are toxic
BUT — IF toxins are a causative factor in your health care problem(s), and — IF toxins are an obstacle to cure

Why We Are Exposed
Part of mom’s toxic burden passed to us
New compounds added to body daily through our nasty habits:
Eating, Drinking, Breathing
Biggest Sources:
Indoor air in our homes and workplaces
Food

Why They Build Up
Our bodies are designed to hold on to fat
Needed for healthy bodies
Historically hard to come by
Fats cannot leave by urination or defecation
Reabsorption of fats — recycling
These fat-resorption mechanisms cannot differentiate between good fats (EFA, fat-soluble vitamins) and DDT!!!
Photo by graham

Worse with Weight Loss
Weight loss increases circulating levels of persistent fat-stored pollutants
Same increase seen after bariatric surgery (increases of 24-52%)
ChevrierJ, et al. Int J Obes Relat Metab Disord 2000;24:1272-8
Hue O, et al. Obes Surg 2006;16:1145-54
Imbeault P, et al. Int J Obes 2001;25:1585-91
Charlier C, et al. In J Obes2002;26:1465-8
Photo by slushpup

Do These Toxins Cause Health Problems?
Photo by D Sharon Pruitt

In Total, the Nine EWG Subjects Carried:
Ü 76 chemicals linked to cancer in humans or animals (average of 53)
Ü 94 chemicals that are toxic to the brain and nervous system (average of 62)
Ü 86 chemicals that interfere with the hormone system (average of 58)
Ü 79 chemicals associated with birth defects or abnormal development (average of 55)
Ü 77 chemicals toxic to the reproductive system (average of 55)
Ü 77 chemicals toxic to the immune system (average of 53)

What are The Main Targets?
These compounds clearly affect:
Immune system
Allergies/Asthma
Chronic infections
Autoimmunity
Nervous system
Endocrine/hormonal system
Generational

How They Cause Damage
Mitochondrial toxicity
Reduce function of mitochondria
Reduced function of cell/organs that contain mitochondria
Oxidative damage
Neurotoxicity
Solvents diminish neural functioning
Pesticides are neurotoxins by design
Photo by get directly down

Associated Adverse Outcomes
Cancer incidences are increasing
“Boomers” have higher rates of cancer than any previous generation
Childhood brain cancers are rising
Asthma rates are rising worldwide
Autism and ADD/ADHD rates are increasing
Chemical Sensitivity
Chronic Fatigue Immune Deficiency Syndrome
Gulf War Syndrome

Presenting As:
Fatigue
Obesity
Diabetes
Fibromyalgia
Cognitive difficulties
Brain Fog
Mood disorders
Tremors
Chronic neurological illnesses
Asthma
Allergies
Chemical sensitivities
Autoimmune conditions
Chronic bacterial, fungal, and viral infections
Certain cancers
Infertility
Hormonal imbalances
Etc.

Why Some People Retain More Toxins Than Others
Genetic differences in phase one and phase two enzymes (polymorphism)
Nutrient deficiencies (Mg,Se,B6)
High sugar, low protein diet
Stress, emotional stuffing, trauma
Heavy metal presence (esp. Hg)
Increased exposure
Photo by get wili hybrid

The Dirty DozenEWG’s 12 most contaminated fruits/vegetables
Peaches 7. Cherries
Apples 8. Pears
Bell Peppers 9. Grapes (imported)
Celery 10. Spinach
Nectarines 11. Lettuce
Strawberries 12. Potatoes
www.ewg.org

EWG’s 12 Least Contaminated Fruits and Vegetables
Onion 7. Sweet peas
Avocado 8. Kiwi fruit
Sweet corn 9. Bananas
Pineapple 10. Cabbage
Mango 11. Broccoli
Asparagus 12. Papaya

Notes: The levels shown on this figure represent the sum of the 12 PCB compounds that resemble dioxin, widely recognized as the most toxic of all industrial pollutants, and linked to cancer as well as to damage of the nervous, reproductive, and immune systems. PCB concentrations are shown as toxic equivalents (TEQs) of 2,3.7,8-Tetrachlorodibenzo-p-dioxin, the benchmark of dioxin chemical. Source: EWG analysis of data from Axys (2003), Easton et al. (2002), EPA (2000a and 2000b), Fiedler et al. (2000), Jacobs et al. (2002), NMFS (2002), NAS (2003), Schecter et al. (2001), and USDA (2002).

The EPA Recommends:
No more than ONE* meal of farmed salmon per MONTH!
(This is based on CANCER risk, not neurobehavioral, endocrine, or immune effects)
½ meal per month if the Salmon
is from Scotland or the Faroe Islands

Butter – The Global PCB Marker
Highest PCB levels in butter from Europe and North America. [i]
Lowest levels were in Australia and New Zealand
Levels of p,p-DDT, p,p-DDE and HCH were highest in butter from areas where those compounds are in regular use (DDT = India and south/central America; HCH = India, China, Spain).
[i]Kalantzi OI, Environ SciTechnol 2001;35(6):1013-1018.

EPA List of Mercury in Fishwww.cfsan.fda.gov/%7Efrf/sea-mehg.htmlMost Toxic Least Toxic
Tilefish (Gulf of Mexico) 1.45 ppm
Shark 0.988
Swordfish 0.976
King Mackerel 0.730
Tuna (bigeye) 0.639
Orange Roughy 0.554
Marlin 0.485
Grouper 0.465
Mackerel Spanish 0.454
Tuna (fresh/frozen) 0.414
Chilean Bass 0.386
Bluefish 0.337
Lobster 0.310
Croaker, white (Pacific) 0.287
Scorpion fish 0.286
Weakfish (Sea trout) 0.256
Halibut 0.252
Sablefish 0.222
Bass (saltwater, black) 0.219
Snapper 0.189
Clam ND
Ocean Perch ND
Salmon (canned) ND
Shrimp ND
Whiting ND
Tilapia 0.010
Oyster 0.013
Salmon (fresh/frozen) 0.014
Hake 0.014
Sardine 0.016
Haddock 0.031
Crawfish 0.033
Pollock 0.041
Anchovies 0.043
Herring 0.044
Flounder/Sole 0.045
Mullet 0.046
Catfish 0.049
Scallop 0.050
Atlantic Mackerel 0.050

What Do Patients and Clinicians Need?

A Current Dilemma(another inconvenient truth)
Natural medicine is built upon finding the nutrient, supplement, or protocol the patient is deficient in which will bring a return to health
All patients are toxic and will NOT get better until the obstacle to cure is identified and removed
Photo by zedzap

What Patients Face
Chronic health problems that current allopathic, naturopathic, and alternative methods are not working for
Realization that this world is toxic
Fear that their problems are caused by a toxic buildup and that no one can help
Photo by DerrickT

What Clinicians Face
Chronically ill patients in whom their sure-fire therapies are not working
An influx of illnesses caused by toxicity (ie. Chemical sensitivity and chronic neurologic problems)that they cannot treat
A knowledge (great or small) that toxins may be the culprit, but not sure how to proceed to confirm the diagnosis

For more information on toxicity testing contact Metametrix at 800.221.4640 or visit www.metametrix.com/toxicity

http://www.metametrix.com	22578
http://gravesnd.blogspot.com	2337
http://www.naturalconnectionshealthcare.com	535
http://www.metametrixinstitute.org	503
http://toxins.metametrix.com	359
https://www.metametrix.com	262
http://www.naturalworldhealing.com	246
http://www.maxwellclinic.com	233
http://translate.googleusercontent.com	84
http://maxwellclinic.com	75
http://bi2016.wikispaces.com	74
http://www.chelationmedicalcenter.com	37
http://gravesnd.blogspot.com.au	31
http://gravesnd.blogspot.in	24
http://chelationmedicalcenter.com	19
http://www.weebly.com	17
http://metametrix.com	16
http://www.drcarlywilleford.com	12
http://stage.metametrix.com	12
http://gravesnd.blogspot.co.uk	12
http://207.46.192.232	11
http://webcache.googleusercontent.com	10
http://www.gravesnd.blogspot.com	9
http://static.slidesharecdn.com	8
http://gravesnd.blogspot.de	8
http://www.coastalcarolinasintegratedmedicine.com	8
http://gravesnd.blogspot.ca	7
http://www.slideshare.net	7
http://stage.metametrixinstitute.org	6
http://naturalconnectionshealthcare.com	6
http://dev-metametrix2	4
http://naturalworldhealing.com	4
http://gravesnd.blogspot.se	3
http://chelationmc.com	3
http://www.google.com	2
http://healthalways.com	2
http://gravesnd.blogspot.it	2
http://mail2.naver.com	1
http://www.metametrixinstitute.org:80	1
http://www.chelationmc.com	1
http://cc.bingj.com	1
http://test.metametrix.com	1
https://s9-us2.ixquick-proxy.com	1

Environmental Toxicity and the Effect on Health

by Augustin Bralley on Jun 29, 2009

Accessibility

Categories

Tags

Upload Details

Usage Rights

43 Embeds 27,572

Statistics

Environmental Toxicity and the Effect on Health — Webinar Transcript