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International Journal Of Computational Engineering Research (ijceronline.com) Vol. 2 Issue. 5



                          Classification of Lung Tumor Using SVM
                           1
                               Ms. Swati P. Tidke, 2Prof. Vrishali A. 3Chakkarwar
                  Department of computer science and engineering, Government College of engineering,
                                              Aurangabad, Maharashtra



Abstract—Lung cancer is the most important cause of              complexity for finding the lung nodules in radiographs are
cancer death for both men and women. Early detection is          as follows:
very important to enhance a patient’s chance for survival of     1. A nodule diameter may be differed from a few
lung cancer. This paper provides a Computer Aided                     millimeters
Diagnosis System (CAD) for early detection of lung cancer        2. Nodules vary widely in density.
nodules from the Chest Computer Tomography (CT)                  3. As nodules can be found anywhere in the lung region,
images. There are five main phases involved in the                    they can be hidden by ribs and structures below the
proposed CAD system. They are image pre-processing,                   diaphragm, resulting in a large variation of contrast to
extraction of lung region from chest computer tomography              the background.
images, segmentation of lung region, feature extraction          4. To overcome these difficulties, the author proposed a
from the segmented region, classification of lung cancer as           Computer Aided Diagnosis (CAD) [2] system for
benign or malignant. Initially total variation based                  detection of lung nodules [3]. The lung tumor
denoising is used for image denoising, and then                       prediction system is shown in Figure 1:
segmentation is performed using optimal thresholding and
morphological operations. Textural features extracted from                                  Input Image
the lung nodules using gray level co-occurrence matrix
(GLCM). For classification, SVM classifier is used. The                          Total variation image denoising
main aim of the method is to develop a CAD (Computer
Aided Diagnosis) system for finding the lung tumor using
the lung CT images and classify the tumor as Benign or                        Segmentation Using Thresholding and
Malignant.                                                                        Morphological Operations
Keywords—Computer Aided Diagnosis System, optimal
thresholding, gray level co-occurrence matrix (GLCM),
Support vector machine (SVM).
                                                                                 Feature Extraction Using GLCM

I.   Introduction
Lung cancer is the leading cause of tumor-related deaths in
the world [1]. At the same time, it appears that the rate has                            SVM classification
been steadily increasing. Lung cancer is caused by the
uncontrolled growth of tissues in the lung. The American
cancer society estimates that 213, 380 new cases of lung
cancer in the U.S will be diagnosed and 160, 390 deaths due
to lung cancer will occur in 2007.The majority of all cases
                                                                                         Benign /Malignant
are caused by tobacco smoking. Exposure to asbestos,                         Fig. 1 lung tumor prediction system
radon, uranium and arsenic are other factors for lung
cancer. Lung cancer is a deadly disease and has chances to       This paper initially apply the different image processing
spread to other parts of the body, e.g. the brain, liver, bone   techniques such as image denoising for removing noise in
and bone marrow. The early detection and diagnosis of            the image, optimal thresholding for converting gray level
nodules in CT image are among the most challenging               image into binary image, morphological operations for
clinical tasks performed by radiologists. Radiologists can       segmentation, feature extraction using GLCM and Support
miss up to 25% of lung nodules in chest radiographs due to       vector machine is used for classification.
the background anatomy of the lungs which can hide the
nodules. Computer aided diagnosis system helps the
radiologists by doing preprocessing of the images and
recommending the most possible regions for nodules. The




Issn 2250-3005(online)                                           September| 2012                              Page1254
International Journal Of Computational Engineering Research (ijceronline.com) Vol. 2 Issue. 5




II. IMAGE PREPROCESSING
CT imaging process may contain various noises. These            IV. Roi Extraction
images      are     not     clean    so     as     to    use   Lung nodules are the small masses of tissue in the lung.
directlyforprocessing,thuswe need to denoise these images.     They appear approximately round and white in CT scan or
The segmenting scheme introduced in this paper performs        X-ray images. In the proposed method our region of interest
an image preprocessing task to remove noise in a lung CT       is lung nodule and labeling algorithm is applied for region
image at first. Total variation denoising is a preprocessing   extraction. Connected component labeling is method of
step to reduce the effect of undesired perturbations. Total    addressing different group of pixels based on their
variation denoising is very effective at simultaneously        characteristics, in this case intensity values of pixels and
preserving edges while smoothing away noise in flat            their neighborhood. There are number of locations where
regions, even at low signal-to-noise ratios. total variation   pixels have same intensity values they are gathered as one
denoising results are shown in figure 2.                       group and uniquely labelled.Labeling is usually used to
                                                               detect connected regions in binary images. Color images
                                                               and data with higher-dimensionality can also be processed.
                                                               In proposed method 4-connected labeling algorithm is used.
                                                               Overview of 4-connected labeling algorithm is as follows:
                                                               • Given a binary image.
                                                               • Negate the image.
        (a) Noisy image     (b) Histogram noisy image          • For every pixel check the north and west pixel.
                                                               • If the pixel to the west or north has the same intensity
                                                               value, the pixel belongs to same region. Assign the same
                                                               label to the current pixel.
                                                               •If the pixel to the west has a different value and the pixel
                                                               to the north has the same value, assign the north pixel’s
      (c) Denoised image (d) Histogram denoised image          label to current pixel.
                                                               •If the north and west neighbors of pixel have different
   Fig. 2 Histogram of lung CT before and after denoising      pixel values, create a new label and assign that label to the
                                                               current pixel.
                                                               • Do this recursively for all pixels that have a 4-
 III. Segmentation Of Lung Region                              connectivity.
In chest CT images, there are two types of pixels with         All pixels above the threshold that have a 4-connectivity
different density distribution:                                will get the same number and thereby each region a unique
1) Pixels within the very dense body and chest wall            label. Find the centroid of each label, if centroid of label is
structures (the body pixels) and 2) low-density pixels.        not present at significant height and width considering our
Optimal thresholding proposed by Shiying et al. [3], is        region of interest eliminates that label. In this way we will
applied on the pre-processed lung image to select a            get desired lung region. The extracted ROIs are then subject
segmentation threshold to separate the body and non-body       to feature extraction for analysis.
pixels through an iterative procedure. Let Ti be the
segmentation threshold after the ith step. To choose a new
segmentation threshold, we apply Ti to the image to
separate the pixels into body and nobody pixels. Let μb and           (a) Optimal thresholding       (b) Holes filling
μn be the mean grey level of body and non-body pixels.
Then new threshold will be:
                                                                          (c) Labeling               (d) Lung region
                                (µb +µn)
                                                                       Fig. 3 Optimal thresholding and morphological
The pixels with a density lower than the threshold value are                            operations
recognized assigned a value 1 and appear white, whereas
other pixels are assigned the value of 0 and appear black.     V. Feature Extraction
The lung image after segmentation with optimal threshold       The extracted ROIs can be distinguished as either cancerous
value contains non-body pixels such as the air surrounding     or not using their texture properties. Gray Level Co-
the lungs, body and other low-density regions within the       occurrence Matrix (GLCM) is one of the most popular ways
image and is removed through morphological operations          to describe the texture of an image. A GLCM denote the
such as erosion, dilation and labeling.                        second order conditional joint probability densities of each
                                                               of the pixels, which is the probability of occurrence of grey




Issn 2250-3005(online)                                         September| 2012                               Page1255
International Journal Of Computational Engineering Research (ijceronline.com) Vol. 2 Issue. 5


level i and grey level j within a given distance ‘d’ and along   hyperplane so that the distance from it to the nearest data
the direction ‘θ’.7 features are considered for proposed         point on each side is maximized. If such a hyper plane
method.                                                          exists, it is known as the maximum margin hyperplane and
1. Area: It gives the actual number of pixels in the ROI.        the linear classifier it defines is known as a maximum
2. Convex Area: It gives the number of pixels in convex          classifier, which is shown in fig.4
image of the ROI.
3. Equivalent Diameter: It is the diameter of a circle with
the same area as the ROI.
                                                                                                          Margin
                                                                        Samples with positive label
           Equivalent Diameter =                  (3)                                                                Separating
                                                                                                                     hyperplane
4. Solidity: It is the proportion of the pixels in the convex
hull that are also in the ROI.

            Solidity =                            (4)
                                                                                                                Samples with
5. Energy: It is the summation of squared elements in the                                                       negative label
GLCM and its value ranges between 0 and 1.

            Energy =                              (5)

6. Contrast: It is the measure of contrast between an
intensity of pixel and its neighboring pixels over the whole
ROI.where N is the number of different gray levels.                           Fig. 4 Maximum margin classifier
                                                         III. Experimental Results And Analysis
           Contrast =                             (6)     The data set used for study of the proposed system consists
                                                          of 25 diseased lung CT JPEG images of size196x257. A
7. Homogeneity: It is the measure of closeness of the
                                                          total of 40 ROIs were extracted. The system was tested with
distribution of elements in the GLCM to the GLCM of each
                                                          15 diseased lung images. The results obtained for a diseased
ROI and its Value ranges between 0 and 1.
                                                          lung image is shown in Fig. 5

            Homogeneity =                         (7)

8. Correlation: It is the measure correlation of pixel to its
neighbor over the ROI.                                                    (a) Original image          (b) Denoised image

             Correlation =                          (8)
9. Eccentricity: The eccentricity is the ratio of the
distance between the foci of the ellipse and its major                   (c) segmented image            (d) tumor region
axis length.                                                      Fig. 5 Results obtained for a diseased lung image In case of
                                                                  SVM classifier out of 9 features at a time only twofeatures
II. Svm Classification
                                                                    are selected for classification, which produces result as
Support vector machines are supervised learning models
                                                                      either benign or malignant. In the proposed method
with associated learning algorithms that analyze data and
                                                                 first two features provides the best results. A few
recognize patterns, used for classification The basic SVM
                                                                 classification results using Support vector machine is listed
takes a set of input data and for each given input, predicts,
                                                                 in table I
which of two classes forms the input, making it a non-
probabilistic binary linear classifier. From given set of
training examples, each marked as belonging to one of two
categories, an SVM training algorithm builds a model that
assigns new examples into one category or the other. In the
proposed method we are using linear classifier. Best hyper
plane is the one that represents the largest separation or
margin between the two classes. So we choose the



Issn 2250-3005(online)                                           September| 2012                              Page1256
International Journal Of Computational Engineering Research (ijceronline.com) Vol. 2 Issue. 5


                                                                      [8]    Kanazawa, K., Kawata, Y., Niki, N., Satoh, H., Ohmatsu, H.,
                    TABLE I                                                  Kakinuma, R., Kaneko, M., Moriyama, N. and Eguchi, K.,
          TUMOR CLASSIFICATION USING SVM                                     “Computer-Aided Diagnosis for Pulmonary Nodules Based
                                                                             on Helical CT
        Image      Output    Classification
                                                                              Images”, Compute Med. Image Graph, Vol. 22, No. 2, Pp.
                   Value                                                     157-167, 1998.
        Image_1    0         Benign                                   [9]    Ayman El-Baz, Aly A. Farag, Robert Falk, Renato La
        Image_2    1         Malignant                                       Rocca, “A Unified Approach for Detection, Visualization
        Image_3    0         Benign                                          and Identification of Lung Abnormalities in Chest Spiral CT
        Image_4    1         Malignant                                       Scan”, Proceedings of Computer Assisted Radiology and
                                                                             Surgery, London 2003.
        Image_5    1         Malignant                                [10]   Samuel G. Armato III, Maryellen L. Giger and Catherine J.
        Image_6    1         Malignant                                       Moran, “Computerized Detection of Pulmonary Nodules on
        Image_7    1         Malignant                                       CT Scans”, Radio Graphics, vol. 19, pp. 1303-1311, and
        Image_8    1         Malignant                                       1999.
                                                                      [11]   S.K.Vijai Anand “Segmentation coupled Textural Feature
        Image_9    0         Benign
                                                                             Classification for Lung Tumor Prediction”, International
        Image_10   1         Malignant                                       Conference on Communication, Control and Computing
                                                                             Technologies 2010.
Conclusion                                                            [12]   M. Gomathi, P.Thangaraj “A Computer Aided Diagnosis
Proposed system helps physician to extract he tumor region                   System for
and evaluate whether the tumor is benign or malignant. The                    Lung Cancer Detection using Machine Learning
computer tomography image is used in this paper. SVM                         Technique”, European Journal of scientific research, Vol.51
provides the accuracy of 92.5%.The accuracy of system can                    No.2, pp.260-275, 2011.
be improved if training is performed by using a very large            [13]   B.Magesh, P.Vijayalakshmi, M. Abirami “computer aided
image database. The different basic image processing                         diagnosis system for identification and classification of
techniques are used for prediction purpose. In the first                     lesions in lungs”, International Journal of Computer Trends
phase the image is denoised. In second phase lung region is                  and Technology- May to June Issue 2011.
                                                                      [14]   Nisar Ahmed Memon, Anwar Majid Mirza, S.A.M. Gilani
separated from surrounding anatomy. In next phase ROI is
                                                                             “Deficiencies Of Lung Segmentation Techniques using CT
extracted, after ROI extraction features extraction is                       Scan Images for CAD”, world Academy of Science,
performed by GLCM. Finally with the obtained texture                         Engineering and Technology 2006.
features classification is performed to detect the occurrence         [15]   Laura Auria1 and Rouslan A. Moro, “Support Vector
of cancer nodules.                                                           Machines (SVM) as a Technique for Solvency Analysis”,
                                                                             Berlin August 2008
REFERENCES                                                            [16]    H. Samet and M. Tamminen (1988). "Efficient Component
[1]   Weir HK et. al.,"Annual report to the nation on the status of          Labeling of Images of Arbitrary Dimension Represented by
      cancer, 1975-2007"Journal National Cancer Institute, vol.              Linear Bintrees". IEEE Transactions on Pattern Analysis
      95 , No. 17.                                                           and Machine Intelligence.
[2]   Ayman El-Baz, Aly A. Farag, Robert Falk, Renato La              [17]     Michael B. Dillencourt and Hannan Samet and Markku
      Rocca, “Detection, Visualization and identification of Lung            Tamminen (1992).”A general approach to connected-
      Abnormalities in Chest Spiral CT Scan: Phase-I”,                       component labeling for arbitrary image representations”.
      International Conference on Biomedical Engineering, Cairo,      [18]   Kenji Suzuki and Isao Horiba and Noboru Sugie. "Linear-
      Egypt, 12-01-2002.                                                     time connected-component labeling based on sequential
[3]   Shiying Hu, Eric A. Huffman, and Joseph M. Reinhardt,"                 local operations". Computer Vision and Image
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[4]   Gurcan, M.N, Sahiner, B., Patrick, N., Chan, H., Kazerooni,            classifiers”.
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[5]   J.Padmavathi, ”A comparative study on breast cancer
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[6]   R.M. Haralick, K. Shanmugam and I.H. Dinstein," Textural
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[7]   R.C. Gonzales and R.E. Woods, Digital Image Processing:
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Issn 2250-3005(online)                                                September| 2012                                  Page1257

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IJCER (www.ijceronline.com) International Journal of computational Engineering research

  • 1. International Journal Of Computational Engineering Research (ijceronline.com) Vol. 2 Issue. 5 Classification of Lung Tumor Using SVM 1 Ms. Swati P. Tidke, 2Prof. Vrishali A. 3Chakkarwar Department of computer science and engineering, Government College of engineering, Aurangabad, Maharashtra Abstract—Lung cancer is the most important cause of complexity for finding the lung nodules in radiographs are cancer death for both men and women. Early detection is as follows: very important to enhance a patient’s chance for survival of 1. A nodule diameter may be differed from a few lung cancer. This paper provides a Computer Aided millimeters Diagnosis System (CAD) for early detection of lung cancer 2. Nodules vary widely in density. nodules from the Chest Computer Tomography (CT) 3. As nodules can be found anywhere in the lung region, images. There are five main phases involved in the they can be hidden by ribs and structures below the proposed CAD system. They are image pre-processing, diaphragm, resulting in a large variation of contrast to extraction of lung region from chest computer tomography the background. images, segmentation of lung region, feature extraction 4. To overcome these difficulties, the author proposed a from the segmented region, classification of lung cancer as Computer Aided Diagnosis (CAD) [2] system for benign or malignant. Initially total variation based detection of lung nodules [3]. The lung tumor denoising is used for image denoising, and then prediction system is shown in Figure 1: segmentation is performed using optimal thresholding and morphological operations. Textural features extracted from Input Image the lung nodules using gray level co-occurrence matrix (GLCM). For classification, SVM classifier is used. The Total variation image denoising main aim of the method is to develop a CAD (Computer Aided Diagnosis) system for finding the lung tumor using the lung CT images and classify the tumor as Benign or Segmentation Using Thresholding and Malignant. Morphological Operations Keywords—Computer Aided Diagnosis System, optimal thresholding, gray level co-occurrence matrix (GLCM), Support vector machine (SVM). Feature Extraction Using GLCM I. Introduction Lung cancer is the leading cause of tumor-related deaths in the world [1]. At the same time, it appears that the rate has SVM classification been steadily increasing. Lung cancer is caused by the uncontrolled growth of tissues in the lung. The American cancer society estimates that 213, 380 new cases of lung cancer in the U.S will be diagnosed and 160, 390 deaths due to lung cancer will occur in 2007.The majority of all cases Benign /Malignant are caused by tobacco smoking. Exposure to asbestos, Fig. 1 lung tumor prediction system radon, uranium and arsenic are other factors for lung cancer. Lung cancer is a deadly disease and has chances to This paper initially apply the different image processing spread to other parts of the body, e.g. the brain, liver, bone techniques such as image denoising for removing noise in and bone marrow. The early detection and diagnosis of the image, optimal thresholding for converting gray level nodules in CT image are among the most challenging image into binary image, morphological operations for clinical tasks performed by radiologists. Radiologists can segmentation, feature extraction using GLCM and Support miss up to 25% of lung nodules in chest radiographs due to vector machine is used for classification. the background anatomy of the lungs which can hide the nodules. Computer aided diagnosis system helps the radiologists by doing preprocessing of the images and recommending the most possible regions for nodules. The Issn 2250-3005(online) September| 2012 Page1254
  • 2. International Journal Of Computational Engineering Research (ijceronline.com) Vol. 2 Issue. 5 II. IMAGE PREPROCESSING CT imaging process may contain various noises. These IV. Roi Extraction images are not clean so as to use Lung nodules are the small masses of tissue in the lung. directlyforprocessing,thuswe need to denoise these images. They appear approximately round and white in CT scan or The segmenting scheme introduced in this paper performs X-ray images. In the proposed method our region of interest an image preprocessing task to remove noise in a lung CT is lung nodule and labeling algorithm is applied for region image at first. Total variation denoising is a preprocessing extraction. Connected component labeling is method of step to reduce the effect of undesired perturbations. Total addressing different group of pixels based on their variation denoising is very effective at simultaneously characteristics, in this case intensity values of pixels and preserving edges while smoothing away noise in flat their neighborhood. There are number of locations where regions, even at low signal-to-noise ratios. total variation pixels have same intensity values they are gathered as one denoising results are shown in figure 2. group and uniquely labelled.Labeling is usually used to detect connected regions in binary images. Color images and data with higher-dimensionality can also be processed. In proposed method 4-connected labeling algorithm is used. Overview of 4-connected labeling algorithm is as follows: • Given a binary image. • Negate the image. (a) Noisy image (b) Histogram noisy image • For every pixel check the north and west pixel. • If the pixel to the west or north has the same intensity value, the pixel belongs to same region. Assign the same label to the current pixel. •If the pixel to the west has a different value and the pixel to the north has the same value, assign the north pixel’s (c) Denoised image (d) Histogram denoised image label to current pixel. •If the north and west neighbors of pixel have different Fig. 2 Histogram of lung CT before and after denoising pixel values, create a new label and assign that label to the current pixel. • Do this recursively for all pixels that have a 4- III. Segmentation Of Lung Region connectivity. In chest CT images, there are two types of pixels with All pixels above the threshold that have a 4-connectivity different density distribution: will get the same number and thereby each region a unique 1) Pixels within the very dense body and chest wall label. Find the centroid of each label, if centroid of label is structures (the body pixels) and 2) low-density pixels. not present at significant height and width considering our Optimal thresholding proposed by Shiying et al. [3], is region of interest eliminates that label. In this way we will applied on the pre-processed lung image to select a get desired lung region. The extracted ROIs are then subject segmentation threshold to separate the body and non-body to feature extraction for analysis. pixels through an iterative procedure. Let Ti be the segmentation threshold after the ith step. To choose a new segmentation threshold, we apply Ti to the image to separate the pixels into body and nobody pixels. Let μb and (a) Optimal thresholding (b) Holes filling μn be the mean grey level of body and non-body pixels. Then new threshold will be: (c) Labeling (d) Lung region (µb +µn) Fig. 3 Optimal thresholding and morphological The pixels with a density lower than the threshold value are operations recognized assigned a value 1 and appear white, whereas other pixels are assigned the value of 0 and appear black. V. Feature Extraction The lung image after segmentation with optimal threshold The extracted ROIs can be distinguished as either cancerous value contains non-body pixels such as the air surrounding or not using their texture properties. Gray Level Co- the lungs, body and other low-density regions within the occurrence Matrix (GLCM) is one of the most popular ways image and is removed through morphological operations to describe the texture of an image. A GLCM denote the such as erosion, dilation and labeling. second order conditional joint probability densities of each of the pixels, which is the probability of occurrence of grey Issn 2250-3005(online) September| 2012 Page1255
  • 3. International Journal Of Computational Engineering Research (ijceronline.com) Vol. 2 Issue. 5 level i and grey level j within a given distance ‘d’ and along hyperplane so that the distance from it to the nearest data the direction ‘θ’.7 features are considered for proposed point on each side is maximized. If such a hyper plane method. exists, it is known as the maximum margin hyperplane and 1. Area: It gives the actual number of pixels in the ROI. the linear classifier it defines is known as a maximum 2. Convex Area: It gives the number of pixels in convex classifier, which is shown in fig.4 image of the ROI. 3. Equivalent Diameter: It is the diameter of a circle with the same area as the ROI. Margin Samples with positive label Equivalent Diameter = (3) Separating hyperplane 4. Solidity: It is the proportion of the pixels in the convex hull that are also in the ROI. Solidity = (4) Samples with 5. Energy: It is the summation of squared elements in the negative label GLCM and its value ranges between 0 and 1. Energy = (5) 6. Contrast: It is the measure of contrast between an intensity of pixel and its neighboring pixels over the whole ROI.where N is the number of different gray levels. Fig. 4 Maximum margin classifier III. Experimental Results And Analysis Contrast = (6) The data set used for study of the proposed system consists of 25 diseased lung CT JPEG images of size196x257. A 7. Homogeneity: It is the measure of closeness of the total of 40 ROIs were extracted. The system was tested with distribution of elements in the GLCM to the GLCM of each 15 diseased lung images. The results obtained for a diseased ROI and its Value ranges between 0 and 1. lung image is shown in Fig. 5 Homogeneity = (7) 8. Correlation: It is the measure correlation of pixel to its neighbor over the ROI. (a) Original image (b) Denoised image Correlation = (8) 9. Eccentricity: The eccentricity is the ratio of the distance between the foci of the ellipse and its major (c) segmented image (d) tumor region axis length. Fig. 5 Results obtained for a diseased lung image In case of SVM classifier out of 9 features at a time only twofeatures II. Svm Classification are selected for classification, which produces result as Support vector machines are supervised learning models either benign or malignant. In the proposed method with associated learning algorithms that analyze data and first two features provides the best results. A few recognize patterns, used for classification The basic SVM classification results using Support vector machine is listed takes a set of input data and for each given input, predicts, in table I which of two classes forms the input, making it a non- probabilistic binary linear classifier. From given set of training examples, each marked as belonging to one of two categories, an SVM training algorithm builds a model that assigns new examples into one category or the other. In the proposed method we are using linear classifier. Best hyper plane is the one that represents the largest separation or margin between the two classes. So we choose the Issn 2250-3005(online) September| 2012 Page1256
  • 4. International Journal Of Computational Engineering Research (ijceronline.com) Vol. 2 Issue. 5 [8] Kanazawa, K., Kawata, Y., Niki, N., Satoh, H., Ohmatsu, H., TABLE I Kakinuma, R., Kaneko, M., Moriyama, N. and Eguchi, K., TUMOR CLASSIFICATION USING SVM “Computer-Aided Diagnosis for Pulmonary Nodules Based on Helical CT Image Output Classification Images”, Compute Med. Image Graph, Vol. 22, No. 2, Pp. Value 157-167, 1998. Image_1 0 Benign [9] Ayman El-Baz, Aly A. Farag, Robert Falk, Renato La Image_2 1 Malignant Rocca, “A Unified Approach for Detection, Visualization Image_3 0 Benign and Identification of Lung Abnormalities in Chest Spiral CT Image_4 1 Malignant Scan”, Proceedings of Computer Assisted Radiology and Surgery, London 2003. Image_5 1 Malignant [10] Samuel G. Armato III, Maryellen L. Giger and Catherine J. Image_6 1 Malignant Moran, “Computerized Detection of Pulmonary Nodules on Image_7 1 Malignant CT Scans”, Radio Graphics, vol. 19, pp. 1303-1311, and Image_8 1 Malignant 1999. [11] S.K.Vijai Anand “Segmentation coupled Textural Feature Image_9 0 Benign Classification for Lung Tumor Prediction”, International Image_10 1 Malignant Conference on Communication, Control and Computing Technologies 2010. Conclusion [12] M. Gomathi, P.Thangaraj “A Computer Aided Diagnosis Proposed system helps physician to extract he tumor region System for and evaluate whether the tumor is benign or malignant. The Lung Cancer Detection using Machine Learning computer tomography image is used in this paper. SVM Technique”, European Journal of scientific research, Vol.51 provides the accuracy of 92.5%.The accuracy of system can No.2, pp.260-275, 2011. be improved if training is performed by using a very large [13] B.Magesh, P.Vijayalakshmi, M. Abirami “computer aided image database. The different basic image processing diagnosis system for identification and classification of techniques are used for prediction purpose. In the first lesions in lungs”, International Journal of Computer Trends phase the image is denoised. In second phase lung region is and Technology- May to June Issue 2011. [14] Nisar Ahmed Memon, Anwar Majid Mirza, S.A.M. Gilani separated from surrounding anatomy. In next phase ROI is “Deficiencies Of Lung Segmentation Techniques using CT extracted, after ROI extraction features extraction is Scan Images for CAD”, world Academy of Science, performed by GLCM. Finally with the obtained texture Engineering and Technology 2006. features classification is performed to detect the occurrence [15] Laura Auria1 and Rouslan A. Moro, “Support Vector of cancer nodules. Machines (SVM) as a Technique for Solvency Analysis”, Berlin August 2008 REFERENCES [16] H. Samet and M. Tamminen (1988). "Efficient Component [1] Weir HK et. al.,"Annual report to the nation on the status of Labeling of Images of Arbitrary Dimension Represented by cancer, 1975-2007"Journal National Cancer Institute, vol. Linear Bintrees". IEEE Transactions on Pattern Analysis 95 , No. 17. and Machine Intelligence. [2] Ayman El-Baz, Aly A. Farag, Robert Falk, Renato La [17] Michael B. Dillencourt and Hannan Samet and Markku Rocca, “Detection, Visualization and identification of Lung Tamminen (1992).”A general approach to connected- Abnormalities in Chest Spiral CT Scan: Phase-I”, component labeling for arbitrary image representations”. International Conference on Biomedical Engineering, Cairo, [18] Kenji Suzuki and Isao Horiba and Noboru Sugie. "Linear- Egypt, 12-01-2002. time connected-component labeling based on sequential [3] Shiying Hu, Eric A. Huffman, and Joseph M. Reinhardt," local operations". Computer Vision and Image Automatic lung segmentation for accurate quantification of Understanding, 2003. volumetric X-Ray CT images", IEEE Transactions on [19] Boser, Bernhard E.,Guyon, Isabelle M., and Vapnik, Medical Imaging, vol. 20, no. 6 ,pp. 490-498, June 2001 Vladimir N.“A training algorithm for optimal margin [4] Gurcan, M.N, Sahiner, B., Patrick, N., Chan, H., Kazerooni, classifiers”. E.A., Cascade, P.N. and Hadjiiski,L., “Lung Nodule Detection on Thoracic Computed Tomography Images: Preliminary Evaluation of a Computer-Aided Diagnosis System”, Medical Physics, Vol. 29, No. 11, Pp. 2552- 2558, 2002. [5] J.Padmavathi, ”A comparative study on breast cancer prediction using RBF and MLP”, International Journal of Scientific and Engineering Research”, Vol.2, Issue.1,2011. [6] R.M. Haralick, K. Shanmugam and I.H. Dinstein," Textural features for image classification," IEEE Transactions on Systems, Man and Cybenatics, vol.3, no. 6, pp. 610-621, Nov. 1973. [7] R.C. Gonzales and R.E. Woods, Digital Image Processing: Pearson Education, 2003. Issn 2250-3005(online) September| 2012 Page1257