Your SlideShare is downloading. ×
 EuroBioForum 2013 - Day 2 | Menno Kok
Upcoming SlideShare
Loading in...5
×

Thanks for flagging this SlideShare!

Oops! An error has occurred.

×

Saving this for later?

Get the SlideShare app to save on your phone or tablet. Read anywhere, anytime - even offline.

Text the download link to your phone

Standard text messaging rates apply

EuroBioForum 2013 - Day 2 | Menno Kok

247
views

Published on

EuroBioForum 2013 2nd Annual Conference …

EuroBioForum 2013 2nd Annual Conference
27-28 May 2013 - Hilton Munich City, Munich, Germany
http://www.eurobioforum.eu/2013

=======================================

# REGIONAL PERSPECTIVES #

Rotterdam Delta, The Netherlands:
What’s keeping medicine from becoming personalised?

Dr Menno Kok,
Advisor Research Strategies Erasmus MC and sector manager Medical Delta

=======================================

http://www.eurobioforum.eu

Published in: Health & Medicine, Business

0 Comments
0 Likes
Statistics
Notes
  • Be the first to comment

  • Be the first to like this

No Downloads
Views
Total Views
247
On Slideshare
0
From Embeds
0
Number of Embeds
1
Actions
Shares
0
Downloads
3
Comments
0
Likes
0
Embeds 0
No embeds

Report content
Flagged as inappropriate Flag as inappropriate
Flag as inappropriate

Select your reason for flagging this presentation as inappropriate.

Cancel
No notes for slide

Transcript

  • 1. 27-28 May 2013, Munich, GermanyEuroBioForum 2013 2nd Annual ConferenceWhat’s keeping medicine…from becoming personalized?Menno Kok
  • 2. • Appr. 14.000 employees, of which > 1500 medical and scientific staff• > 40.000 patients admitted• > 500.000 visits to outpatient clinics• 27,700 operations (incl. day treatment)• Appr. 3000 medical students• 28 medical specialty training courses• > 1000 PhD students• > 400 transplantations/y• 400-450 new clinical trials/y• Budget € 1.3 billionErasmus University Medical Center, Rotterdam
  • 3. Top Reference and Top Clinical Care:Cardio-Vascular (Thorax Centre)Clinical GeneticsGastero-EnterologyInfectious Diseases, VirologyOncology (Daniel den Hoed Clinic)Pediatrics (Sophia Children’s Hospital)Transplantation (Liver, Kidney, Heart,Lung, Bone Marrow)TraumatologyResearch:CardiovascularOncologyCell Biology & GeneticsImmunology & HaematologyNeurosciencesPediatricsMedical Technology/ImagingEpidemiology and Public HealthHealth Policy and Management*Erasmus University Medical Center, Rotterdam
  • 4. Personalized MedicinePersonalized medicine generates and uses all the relevant informationavailable on the individual patient to make informed choices betweentreatment options and fine-tune these subsequently.Main activities of Erasmus MC:- Cancer (breast, colon, lung, prostate, skin, brain, leukemia);- Cardiovascular dis.;- Medical Informatics (phase IV); Bio-informatics- Imaging, -omics- HTACollaborative efforts:- All strategic research in national and mostly international collaboration;- Epidemiological research (coupled cohorts);- String of pearls 8  13 disease area’s, connection to electronic patient files.
  • 5. Personalized MedicinePersonalized medicine generates and uses all the relevant informationavailable on the individual patient to make informed choices betweentreatment options and fine-tune these subsequently.is it really all about genetics?
  • 6. Personalized MedicineGenetic variationEpigenetic variationAge (life stage)Food intakeCircadian clockStressImpaired organ functionOther confounding conditionsBody sizeMicrobiomePrevious exposurePhysical and mental activity
  • 7. FunctionPersonalized HealthLife phase: I II III IV
  • 8. FunctionAnnual costPersonalized HealthInclusion inclinical trialsLife phase: I II III IV
  • 9. Personalized HealthPersonalized Health generates and uses all the relevant informationavailable on the individual citizen to provide him/her with advice on healthissues, life style, work-life management, physical and socio-psychologicalcapacity building and (other) preventive options.Main hurdles:At research level: evidence baseAt implementation level: reimbursement modelsAt execution level: acceptance and adherencePersonalized Medicine generates and uses all the relevant informationavailable on the individual patient to make informed choices betweentreatment options and fine-tune these subsequently.
  • 10. Personal perspectiveEmpirical (genetic) data changes the way individuals perceive themselves andtheir families, and change the way others see them (Taylor, 2008)Self management: personalized health shifts the responsibility for good healthfrom government and collectives to the individual, who becomes responsiblefor his/her own health or disease (Savond, 2013).Patient centered medicine requires patient centered decision-making, healthliteracy, trusted information sources, and better communication to start with.
  • 11. 1. Innovation in clinical trials;2. Develop point of care devices and technologies;3. Promote personalized health.TOP 3 recommendations: