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Asking The Right Questions - they key to preventing persistent pain?
The document discusses how the brain produces pain and protective responses through nociception and various neural pathways and networks in the brain. It explains that nociception occurs automatically through basic motor responses and sympathetic nervous system responses without conscious awareness. However, the brain can modulate pain through factors like beliefs, knowledge, context and memory. Central sensitization can also cause normally non-painful stimuli to produce pain responses through sensitization of nociceptors and neural pathways in the spinal cord and brain.
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Asking The Right Questions - they key to preventing persistent pain?
- 1. Asking the right questions. bim www.bodyinmind.com.au The key to preventing persistent pain? Lorimer Moseley NHMRC Senior Research Fellow Prince of Wales Medical Research Institute & School of Medical Sciences, University of New South Wales, Sydney, Australia
- 2. www.bodyinmind.com.au Š lorimer moseley2010 It is all about protection Basic motor response Coordinated motor response Memory response Nociception Sympathetic nervous system response Endocrine system response Immune system response Consciously motivated behaviour Pain
- 3. Nociception to the brain www.bodyinmind.com.au Š lorimer moseley 2010 thalamus âDanger in my areaâ
- 4. Nociception to the brain www.bodyinmind.com.au Š lorimer moseley 2010 - Relay/prio ritisation centre ant thalamus âwhat i s the most import know thin g for the brain to â about right now? Site of the famous pain gate
- 5. Nociception to the brain www.bodyinmind.com.au Š lorimer moseley 2010 thalamus There are actually 3 different types of these...
- 6. Nociception to the brain www.bodyinmind.com.au Š lorimer moseley 2010 thalamus Periaqueductal Gray There are about 600 descending neurons for every spinal nociceptor. 600 1
- 7. Nociception to the brain www.bodyinmind.com.au Š lorimer Projections to PAG come from moseley 2010 all over the brain thalamus Periaqueductal Gray
- 8. Nociception to the brain All happens without us knowing about it thalamus Can activate protective responses without us knowing about it Nociception is happening now Right now. www.bodyinmind.com.au Š lorimer moseley 2010
- 9. Acute pain basics www.bodyinmind.com.au Šlorimer moseley 2010
- 10. Pain emerges fromthe brain with activity in a particular and peculiar network of brain areas Individually specific Every brain cell involved also does other things Hoffman et al (2004) NeuroReport Text Obliteration of one ânodeâ does not remove pain - the brain works out how to produce pain Professor Wiki Pedia (2010) using other brain cells. MacIver et al (2008) Brain www.bodyinmind.com.au Š lorimer moseley 2010
- 11. How does thebrain produce a conscious protective response? www.bodyinmind.com.au Š lorimer moseley 2010
- 12. Denote synaptic modulation www.bodyinmind.com.au Šlorimer moseley 2010 Beliefs Knowledge, logic Other sensory cues Social context Anticipated consequences Family media previous history media solicitor culture case manager GP finances GFC work 9/11 physical therapist season allergies & illnesses education faith activity self-efficacy fashion self-efficacy access worry previous exposure love etc etc etc www.bodyinmind.com.au
- 13. Beliefs Pain Knowledge, logic Other sensory cues Social context Anticipated consequences Family media previous history Itâs not that culture GP Relay 2: The thalamus dangerous work physiotherapist education activity self-efficacy access exposure media solicitor case manager finances GFC 9/11 season allergies & illnesses faith fashion self-efficacy worry love etc etc etc - Relay 1: The dorsal horn www.bodyinmind.com.au Š lorimer moseley 2010 Danger
- 14. Beliefs Pain Knowledge, logic Other sensory cues Social context Anticipated consequences Family media previous history Itâs more culture GP Relay 2: The thalamus dangerous work physiotherapist education than that activity self-efficacy access exposure + Relay 1: The dorsal horn www.bodyinmind.com.au Š lorimer moseley 2010 Danger
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- 16. Normal state www.bodyinmind.com.au Š lorimermoseley 2010 Nociceptors & descending modulation
- 17. Normal state Sensitised spinal www.bodyinmind.com.au nociceptor Š lorimer moseley 2010 Nociceptors & descending modulation
- 18. Normal state Sensitised Really spinal sensitised www.bodyinmind.com.au nociceptor spinal Š lorimer moseley 2010 nociceptor Nociceptors & descending modulation
- 19. www.bodyinmind.com.au Š lorimer moseley2010 Pain Beliefs Knowledge, logic Other sensory cues Social context Anticipated consequences Family media previous history media culture solicitor case manager GP finances work GFC 9/11 physiotherapist season education allergies & illnesses activity self-efficacy faith fashion access self-efficacy worry love exposure etc etc etc
- 20. www.bodyinmind.com.au Š lorimer moseley2010 Contributions to threat Do you have: burning, shooting pain, allodynia? Cognitive Function Sensitisation et al Thoughts Impact on activity Peripheral Beliefs Everyday tasks neuropathia Worry central sensitisation Bothersomeness brain changes
- 21. www.bodyinmind.com.au Š lorimer moseley2010 Contributions to threat Do you have: pain spreading down arms or legs, back - neck or neck - back? Cognitive Function Sensitisation et al Thoughts Impact on activity Peripheral Beliefs Everyday tasks neuropathia Worry central sensitisation Bothersomeness brain changes
- 22. www.bodyinmind.com.au Š lorimer moseley2010 Contributions to threat Is there evidence of autonomic dysfunction? (swelling, colour) Cognitive Function Sensitisation et al Thoughts Impact on activity Peripheral Beliefs Everyday tasks neuropathia Worry central sensitisation Bothersomeness brain changes
- 23. www.bodyinmind.com.au Š lorimer moseley2010 Contributions to threat What sort of thoughts do you have about your pain/injury? Cognitive Function Sensitisation et al Thoughts Impact on activity Peripheral Beliefs Everyday tasks neuropathia Worry central sensitisation Bothersomeness brain changes
- 24. www.bodyinmind.com.au Š lorimer moseley2010 Contributions to threat What do you believe is the cause of your pain? Do you think it will get better? Cognitive Function Sensitisation et al Thoughts Impact on activity Peripheral Beliefs Everyday tasks neuropathia Worry central sensitisation Bothersomeness brain changes
- 25. www.bodyinmind.com.au Š lorimer moseley2010 Contributions to threat How often/much are you worrying about your pain? Cognitive Function Sensitisation et al Thoughts Impact on activity Peripheral Beliefs Everyday tasks neuropathia Worry central sensitisation Bothersomeness brain changes
- 26. www.bodyinmind.com.au Š lorimer moseley2010 Contributions to threat How bothered by your pain are you? Are you enjoying things as much as normal? Cognitive Function Sensitisation et al Thoughts Impact on activity Peripheral Beliefs Everyday tasks neuropathia Worry central sensitisation Bothersomeness brain changes
- 27. www.bodyinmind.com.au Š lorimer moseley2010 Contributions to threat Is this threatening your quality of life? Cognitive Function Sensitisation et al Thoughts Impact on activity Peripheral Beliefs Everyday tasks neuropathia Worry central sensitisation Bothersomeness brain changes
- 28. Back pain specific www.bodyinmind.com.au Šlorimer moseley 2010
- 29. Back pain specific www.bodyinmind.com.au Pain specific Š lorimer moseley 2010 I have burning, shooting pain: my skin is sensitive to touch
- 30. What to doif not low risk.... 1. Remove the threats you can, cope with those you canât. www.bodyinmind.com.au Š lorimer moseley 2010 Cognitive Function Sensitisation ise, Impact on activity et al Thoughts , bi olog plain learn Everyday tasks Peripheral E x ure, Beliefs neuropathia r ea s Worry s ope to c central how sensitisation Bothersomeness brain changes
- 31. What to doif not low risk.... 1. Remove the threats you can, cope with those you canât. 2. Gradually www.bodyinmind.com.au expose to all identified threats. Š lorimer moseley 2010 Cognitive Function Sensitisation ise, Impact on activity et al Thoughts , bi olog plain learnraded extaskssu Peripheral E x Beliefs , G Everyday po re ure neuropathia r ea s Worry s ope to c central how sensitisation Bothersomeness brain changes
- 32. What to doif not low risk.... 1. Remove the threats you can, cope with those you canât. 2. Gradually expose to all identified threats. 3. Maximise health of the tissues, the nerves & the brain. Cognitive Function Sensitisation ise, Impact on activity Trai n the et al Thoughts bio log body & Exp lain, rn Everyday tasks thePeripheral Beliefs e , leaGraded exposure brain! neuropathia Worry s sur rea c ope central to h ow Bothersomeness sensitisation brain changes www.bodyinmind.com.au Š lorimer moseley 2010
- 33. bim Blog Slides for your use Articles Seminars www.bodyinmind.com.au Books