Your SlideShare is downloading. ×
0
Approach to the child with rash
Approach to the child with rash
Approach to the child with rash
Approach to the child with rash
Approach to the child with rash
Approach to the child with rash
Approach to the child with rash
Approach to the child with rash
Approach to the child with rash
Approach to the child with rash
Approach to the child with rash
Approach to the child with rash
Approach to the child with rash
Approach to the child with rash
Approach to the child with rash
Approach to the child with rash
Approach to the child with rash
Approach to the child with rash
Approach to the child with rash
Approach to the child with rash
Approach to the child with rash
Approach to the child with rash
Approach to the child with rash
Approach to the child with rash
Approach to the child with rash
Approach to the child with rash
Approach to the child with rash
Approach to the child with rash
Approach to the child with rash
Approach to the child with rash
Approach to the child with rash
Approach to the child with rash
Approach to the child with rash
Approach to the child with rash
Approach to the child with rash
Approach to the child with rash
Approach to the child with rash
Approach to the child with rash
Approach to the child with rash
Approach to the child with rash
Approach to the child with rash
Approach to the child with rash
Upcoming SlideShare
Loading in...5
×

Thanks for flagging this SlideShare!

Oops! An error has occurred.

×
Saving this for later? Get the SlideShare app to save on your phone or tablet. Read anywhere, anytime – even offline.
Text the download link to your phone
Standard text messaging rates apply

Approach to the child with rash

1,235

Published on

0 Comments
4 Likes
Statistics
Notes
  • Be the first to comment

No Downloads
Views
Total Views
1,235
On Slideshare
0
From Embeds
0
Number of Embeds
0
Actions
Shares
0
Downloads
94
Comments
0
Likes
4
Embeds 0
No embeds

Report content
Flagged as inappropriate Flag as inappropriate
Flag as inappropriate

Select your reason for flagging this presentation as inappropriate.

Cancel
No notes for slide

Transcript

  • 1. Approach to the patient with rash Dr AJIT GADEKAR
  • 2. High yield facts • Primary lesions are uncomplicated abnormalities which represent initial pathologic change. • Secondary changes reflect progression of disease eg excoriation , infection , keratinization. • Physician must search for the primary lesion
  • 3. High yield facts • Look at the morphology and grouping to reach the diagnosis • Clinician must know the pattern of emergency dermatologic conditions • Clinician must communicate to the patient that there are times when it is difficult to narrow the final diagnosis to single entity
  • 4. Aim • To classify benign vs malignant • To know which need urgent care from those which do not
  • 5. History : series of questions • What do the patient think is causing rash? • Where did the lesions originate? • When did the lesion first develop? & what has been the progression of rash • Was there any prodrome to the lesions? • What are the associated symptoms?
  • 6. History : series of questions • Does it itch , hurt etc? • What treatment was applied if any? • Is there h/o atopy in family? • What medication do they take regularly or intermittently? • What kind of exposure do they have? • Family history of skin related disorder?
  • 7. Physical • Diagnosis relies heavily on careful inspection of the skin. • Examine in well-lit area where one can examine the entire skin surface • Entire eruption should be visualized to evaluate distribution and configuration • Most important objective is to characterize the morphology of the primary lesion • Description of rash should include morphology, color, configuration and distribution
  • 8. Morphology : primary & secondary lesions • Primary lesions are uncomplicated abnormalities which represent initial pathologic change • Secondary changes reflect progression of disease such as excoriation , infection or keratinization • Morphologic expression of dermatologic condition is basic entity on which all diagnosis are founded
  • 9. Primary lesions • Macule : circumscribed flat discoloration < 1cm in diameter eg ash-leaf spots, flat nevi and freckle • Patch : circumscribed flat discoloration > 1cm in diameter eg vitiligo, tinea versicolor. Often have fine scale (pityriasis alba)  Papule : circumscribed superficial solid elevated lesion < 1cm ,eg warts, elevated nevi insect bites molluscum contagiosum.
  • 10. Primary lesions • Plaque : > 1cm elevated flat top superficial lesion eg psoriasis and pityriasis rosea. • Vesicle : fluid filled lesion < 1cm in diameter eg herpes simplex and varicella • Bulla : fluid filled lesion > 1cm in diameter eg ssss and bullous impetigo • Pustule: vesicle with purulent exudates eg acne , folliculitis
  • 11. Primary lesions • Nodule : lesion < 1cm in diameter with depth eg secondary / tertiary syphilis • Tumor : > 1cm solid lesion with depth • Petechiae : pinpoint < 1cm flat red spots under the skin surface • Purpura : > 1cm visible collection blood eg itp • Wheal : transient edematous papule or plaque with pale center and pink margin, peripheral erythema eg hives and insect bites
  • 12. Secondary lesions • Scales : dry and greasy masses of keratin ranging from fine and delicate to coarse , implies pathologic process in epidermis • Crust : dried exudates ( pus or blood) • Excoriation : linear abrasion caused by scratching • Fissure : linear crack or cleavage on skin with sharply defined margins
  • 13. Secondary lesions • Ulcer :depressed lesion with epidermal & dermal loss • Scar : permanent lesion result from process of repair by replacing connective tissue • Lichenification : area of increased epidermal thickness with accentuation of skin
  • 14. Diagnostic features of lesion • Distribution • Configuration • Color • Texture sandpaper texture in scarlet fever • Positive nikolskys sign epithelial shearing caused by lateral pressure to unblistered skin
  • 15. Distribution
  • 16. Configuration • General shape or the pattern in which the lesion are arranged • Lesions may be grouped into a pattern eg grouped papule in molluscum contagiosum • Form specific shape annular plaque of tinea corporis • Herpes simplex typically present in grouped vesicles
  • 17. An algorithmic approach
  • 18. True emergencies in the pediatric dermatologic presentation • Toxic epidermal necrolysis (TEN) • Stevens Johnson syndrome (SJS) • Staphylococcal scalded skin syndrome (SSSS) • Toxic shock syndrome (TSS) • Kawasaki disease (KD) • Anaphylaxis • Purpura fulminans
  • 19. Toxic epidermal necrolysis (TEN) • Definition : sudden onset : generalization in 24 – 48hrs : widespread blister formation : confluent erythema : skin tenderness : absence of target lesion : sever form of EM • Hypersensitivity that result in damage to basal layer of epidermis
  • 20. Toxic epidermal necrolysis • Nikolskys sign positive • Fever , inflammation of eyelid , conjunctivae, mouth precedes skin lesion • Complicated by dehydration shock electrolyte imbalance septicemia
  • 21. Stevens-johnson syndrome • Erythema , edema of lips , buccal mucosa • Then devolopes bullae ulceration hemorrhagic crusting • Skin lesions are bullae denuded skin .more widespread than EM • Skin tenderness is minimal to absent • Pain from mucosal ulceration is painful • Systemic involvement present
  • 22. SSSS • Caused predominantly by phage group 2 staphylococci , strain 71 & 55 • Common in infant and young children's • Clinical features are mediated by hematogenous spread in absence of specific antitoxin antibody to staphylococcal epidermolytic or exfoliative toxins A or B • ↓ clearance of these toxin in young infant
  • 23. SSSS • Range from localized bullous impetigo to generalized cutaneous involvement with systemic illness • Begins as cutaneous scarlentiform erythema • Desquamative phase begins 5 days after cutaneous erythema • Sterile flaccid blisters devolopes diffusely • Intact bullae are consistently sterile unlike in bullous impetigo
  • 24. SSSS
  • 25. SSSS • Nikolskys sign positive . • Absence of inflammatory infiltrate is charecteristics • semisynthetic penicillinase resistant penicillin should be prescribed as staphylococci are resistant to penicillin
  • 26. Erythema multiforme • Characterized by abrupt , symmetric cutaneous eruption mostly on extensor upper extremities • EM has numerous morphologic manifestation on the skin , varying from erythematous macules , papules , vesicles , bullae , or urticaria appearing plaques. • Classic lesions doughnut-shaped, target like (iris or bulls eye) papule with erythematous outer border an inner pale ring dusky purple to necrotic center
  • 27. Target or iris lesion with dusky zone on palm with EM due to HSV
  • 28. Early fixed papule with central dusky zone on dorsum of hand in EM
  • 29. EM etiology • Infection with HSV is most common. • HSV labialis & HSV genitalis implicate in 60% of episode of EM. • Trigger nearly all episodes of recurrent EM • HLA B35 / B62 / DR53 is associated with an increased risk of HSV induced EM (recurrent).
  • 30. Recurrent labial HSV
  • 31. Meningococcemia • Fever • Rash typically petechiae & purpura • Hypotension • Adrenal failure • Multiorgan failure • meningitis feature
  • 32. Anaphylaxis • Life threatening allergic reaction • Urticaria • angioedema • Wheezing • dyspnea • Hypotension • All these in few seconds to minutes of exposure
  • 33. Purpura fulminance • Life threatening hemorhagic disease seen in setting of sepsis • Skin lesions lead to perivascular hemorrhage and necrotic gangrene • Presentation typically include fever hypotension DIC
  • 34. Conclusion • Approach to pediatric dermatology patient in the ED may appear daunting however with a systemic approach one can more readily and successfully arrive at a diagnosis and manage the patient effectively
  • 35. Thank you…………………………………….

×