1. Irrational Drug Use for
Neuropathic Pain
Ersin Tan, MD
8th Neuropathic Pain Symposium

2. Irrational Drug Use for the Treatment of
Neuropathic Pain
Neuropathic pain,
• May be efficiently treated with some antiepileptics, some anti-depressant drugs and
narcotic drugs,
• Does not show a good response to the
treatment with anti-inflammatory drugs and
opioids.
Serpell MG. Pain 2002;99:557-66

3. ACCORDING TO AASPE GUIDELINE...
Argoff CE. Consensus Guidelines: Treatment Planning and Options. Mayo Clin. Proc.
April 2006; 81(4, suppl): S12-S25.
*

4. Irrational Drug Use for the Treatment of
Neuropathic Pain
However, in our country, also the drug classes without
indication and efficacy, such as NSAIDs, central
muscular relaxants, vitamins, and non-narcotic
analgesics, are commonly prescribed due to
diagnosis of neuropathic pain.
These therapeutic approaches can be considered as
irrational drug use.
IMS reçete datası. MAT 06 2008 Nöropatik Ağrı reçeteleri

5. SNAPS – Information formation

New data formation for irrational drug use.
Prescription
NSAIDs
Central Muscular Relaxant
Non-narcotic analgesics
Vitamines D/E/F
Irrational Drug Use
(PPI, except the cost of side
effects)
Anti-depressants
Anti-epileptics
Rational Drug Use
Cost
2008
3.208.244
2.591.334
396.218
1.317.503
2009
Increase
3.561.401 11%
2.849.771 10%
553.203 40%
1.396.379
6%
2008
17.824.521
20.072.965
944.602
9.082.446
2009
Increase
22.001.268
23%
26.543.947
32%
1.543.426
63%
10.627.264
17%
7.513.299
8.360.754
11%
47.924.534
60.715.905
27%
153.698
979.360
1.133.058
97.048
1.192.839
1.289.887
-37%
22%
14%
688.714
50.076.384
50.765.098
888.424
63.350.956
64.239.380
29%
27%
27%
2008
2009
Rational Drug Use
51%
51%
Irrational Drug Use (PPI; except
the cost of side effects)
49%
49%