2. Blister aneurysms …
Classical ICA blister aneurysms
Dissecting aneurysm with a bleb
Very small berry aneurysms
3. Small Blister/dissecting…
“Very small, friable, symptomatic”
Blister aneurysms (BA) are rare lesions characterized by a
hemispherical shape and fragile walls
Non-branching sites from the dorsomedial wall of the
internal carotid artery (ICA), anterior communicating
(AComA) and basilar artery …
Small size & atypical location- RA & 3D needed
Blister/disecting- rapid change in size and morphology in
follow-up angiograms
Owaga A et al , Neurosurgery 2000;47:578
Meling TR et al J Neurosurg 2008;108:662
Sim SY et al J Neurosurg 2006;105:400
4. Management…
Pathology - focal wall defects covered by a thin layer of fibrous
tissue and adventitia and lack of usual collagenous layer
Surgical Options - Direct clipping, clipping plus wrapping,
wrapping alone, clipping with Sundt encircling graft clips, encircling
silicone clip application, primary suturing of ICA, vascular staple clip
closure of ICA and trapping with or without extracranial-intracranial
bypass
High risk of premature rupture during surgery, large lacerations
Endovascular- difficult to coil, friable, continued growth, stent
needed (issues in SAH)
Shikawa T, Neurosurgery 1997;40:403
Lee BH et al J Neurosurg 2008
15. 17 patients: SS, ODS, SS+Coil
1 rebleed (died)
Good outcome on f/u – 82%
Mortality – 18%
Blister Aneurysm
16. Our experience with FD vs non FD
Complete occlusion – 89% vs 71% i.f.o FD
Repeat treatment – none vs 11.7% i.f.o FD
Rebleed resulting in death – none vs 5.8% i.f.o FD
Submitted for publication
17. Learning points
• FD was safe and effective in these aneurysms and
compared favorably with our previously reported results
with stent(single/overlapping) and coiling
• In our series loading with Pasugrel and ecospirin was
safe and effective for flow diverter placement in acutely
ruptured blister aneurysms
Antiplatelet protocol: 2 hrs prior to stent
deployment
Ecosprin 150 mg & Prasugrel 50 mg
Heparin 3000 IU at start of procedure
1000 IU to 2000 IU prior to stent deployment
ACT 300 (x 2 upper limit of normal)
26. Small blister/dissecting
Small blister/dissecting- important to detect
and recognize
Difficult cases for surgery or endovascular
Previous Options- single stent, overlapping
stents, stent and coil
Current TOC in ICA – FD
Careful anti-platelet protocol
Distinguish between blister vs dissecting vs
very small berry
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