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FLOW DIVERTERS FOR
CERBERAL ANEURYSMS
Vipul Gupta
Artemis Hospitals
Gurgaon
India
Endovascular mgt of aneurysms….
Issues..
 Large and giant aneurysms
 Fusiform/dissecting aneurysms
 Blister aneurysms
 Small dysplastic aneurysms
1917
pts.
451
patients
ISUIA Trial
Large, giant aneurysms
 Classically - Surgery treatment of choice -
Better occlusion, more permanent, mass
effect
 Endovascular – safer, issue of
residual/recurrences; mass effect of coils
Stents
 Flow modification
 Intimal growth and healing
 Change of angles
Flow modification/diversion-
Flow diversion with stents- single, overlapping
Further evolution – flow diverters (stents)
0
1
2
3
4
5
6
7
8
9
10
0 10 20 30 40 50 60 70 80 90 100
Flow
index
Ineffective
(clotting)
Ineffective
(free flow)
Effective flow
diversion and side
branch patencyOptimizing
flow diversion
A B
Cavernous aneurysms
26 year old,
Cranial nerve palsy
B
G
Large ICA aneurysms …
• Complete occlusion – 90 %, no recurrences
• Complication rate – 2-8 %
• Careful placement , avoid overlapping
devices, anti-platelet regime
Small Blister/dissecting…
 Blister aneurysms (BA) are rare lesions
characterized by a hemispherical shape and
fragile walls
 Surgical Options - Direct clipping, clipping plus
wrapping, wrapping alone, clipping with Sundt
encircling graft clips, encircling silicone clip
application, primary suturing of ICA, vascular
staple clip closure of ICA and trapping with or
without extracranial-intracranial bypass
 High risk of premature rupture during surgery,
large lacerations
 Endovascular- difficult to coil, friable,
continued growth, stent needed (issues in
SAH), single/overlapping
Classical blister aneurysm
34-year M, SAH
D E F
B CA B
B
C D
A
Blister Aneurysm
Our experience with FD vs non FD
FD – 11 cases
Complete occlusion – 89% vs 71% i.f.o FD
Repeat treatment – none vs 11.7% i.f.o FD
Rebleed resulting in death – none vs 5.8% i.f.o FD
Submitted for publication
Small ICA aneurysms …
Dissections with blister
2-overlapping Enterprise stents
Posterior circulation aneurysms …
Distal bifurcation aneurysms
Intermediate Flow diverters (FRED junior)
Is it all easy ….
Progressive intraaneurysmal
partial thrombosis starts
8th DAY POST COILING PRESENTED WITH VERTIGO AND HEADACHE
56 yr old,
ischaemic
stroke
Flow diverters …
 Major evolution of EVT of aneurysms
 TOC for large/giant ICA aneurysms
 Blister/small dysplastic aneurysms
 Posterior circulation – more careful use
 Evolving – distal aneurysms
 Issues – cost, expertise, posterior ciruclation
giant aneurysms …
For more information on:
STROKE & NEUROVASCULAR INTERVENTIONS:
URL:
www.sanif.co.in
Facebook:
https://www.facebook.com/strokeawarenessindia
https://www.facebook.com/vipul.gupta.35175
Twitter
https://twitter.com/drvipulgupta25
LinkedIN
https://in.linkedin.com/pub/dr-vipul-gupta/51/8a1/25a
YouTube
Channel: Stroke & Neurovascular Interventions
www.youtube.com/c/StrokeNeurovascularInterventionsfoundation
Dr Vipul Gupta
Thank you ….

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Flow diverters for cerberal aneurysms

  • 1. FLOW DIVERTERS FOR CERBERAL ANEURYSMS Vipul Gupta Artemis Hospitals Gurgaon India
  • 2. Endovascular mgt of aneurysms…. Issues..  Large and giant aneurysms  Fusiform/dissecting aneurysms  Blister aneurysms  Small dysplastic aneurysms
  • 4. Large, giant aneurysms  Classically - Surgery treatment of choice - Better occlusion, more permanent, mass effect  Endovascular – safer, issue of residual/recurrences; mass effect of coils Stents  Flow modification  Intimal growth and healing  Change of angles
  • 5. Flow modification/diversion- Flow diversion with stents- single, overlapping Further evolution – flow diverters (stents)
  • 6. 0 1 2 3 4 5 6 7 8 9 10 0 10 20 30 40 50 60 70 80 90 100 Flow index Ineffective (clotting) Ineffective (free flow) Effective flow diversion and side branch patencyOptimizing flow diversion
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  • 13. A B Cavernous aneurysms 26 year old, Cranial nerve palsy B G
  • 14.
  • 15. Large ICA aneurysms … • Complete occlusion – 90 %, no recurrences • Complication rate – 2-8 % • Careful placement , avoid overlapping devices, anti-platelet regime
  • 16. Small Blister/dissecting…  Blister aneurysms (BA) are rare lesions characterized by a hemispherical shape and fragile walls  Surgical Options - Direct clipping, clipping plus wrapping, wrapping alone, clipping with Sundt encircling graft clips, encircling silicone clip application, primary suturing of ICA, vascular staple clip closure of ICA and trapping with or without extracranial-intracranial bypass  High risk of premature rupture during surgery, large lacerations  Endovascular- difficult to coil, friable, continued growth, stent needed (issues in SAH), single/overlapping
  • 18. D E F B CA B
  • 20.
  • 21. Blister Aneurysm Our experience with FD vs non FD FD – 11 cases Complete occlusion – 89% vs 71% i.f.o FD Repeat treatment – none vs 11.7% i.f.o FD Rebleed resulting in death – none vs 5.8% i.f.o FD Submitted for publication
  • 23.
  • 24. Dissections with blister 2-overlapping Enterprise stents Posterior circulation aneurysms …
  • 25.
  • 26.
  • 27.
  • 30. Is it all easy ….
  • 31.
  • 32.
  • 33. Progressive intraaneurysmal partial thrombosis starts 8th DAY POST COILING PRESENTED WITH VERTIGO AND HEADACHE
  • 35. Flow diverters …  Major evolution of EVT of aneurysms  TOC for large/giant ICA aneurysms  Blister/small dysplastic aneurysms  Posterior circulation – more careful use  Evolving – distal aneurysms  Issues – cost, expertise, posterior ciruclation giant aneurysms …
  • 36. For more information on: STROKE & NEUROVASCULAR INTERVENTIONS: URL: www.sanif.co.in Facebook: https://www.facebook.com/strokeawarenessindia https://www.facebook.com/vipul.gupta.35175 Twitter https://twitter.com/drvipulgupta25 LinkedIN https://in.linkedin.com/pub/dr-vipul-gupta/51/8a1/25a YouTube Channel: Stroke & Neurovascular Interventions www.youtube.com/c/StrokeNeurovascularInterventionsfoundation Dr Vipul Gupta