2013. 5. 313조 발표자 : 36번 송혜민Short Term Clinical Efficacy of Newmeridol HALITOSIS tooth & tongue gel inCombination with a To...
• 87% 환자가 충치로 인해 구취를 겪고 있으며, 51%는 tongue coating, 17%는치은염, 15%는 치주염, 17%는 여러 복합요인이 있다.• 특히 혀의 뒷부분은 해부학적 구조에 의해 혐기성 세균의 서식처...
• Study Design and Population1. single-center에서 (independent dermatological researchinstitute), examiner-blind, randomized...
• Wash-in and Wash-out Period• 최상의 구강 분석하기 위해서 baseline 측정을 위해 최소 일주일전에 피실험자들은 감독관의 지시를 받음.• 피실험자들은 standard fluoride toot...
• Application ModeMaterials and Methods
• Organoleptic Ratings (Ors)0 = Odor cannot be detected1 = Questionable malodor, barely detectable2 = Slight malodor, exce...
Materials and Methods• VSC Measurements Using a Gas ChromatographObjective measurementDetects VSC with appropriatemonitor;...
• Organoleptic EvaluationResults
• VSC ConcentrationsResults
• 구취제거에는 기계적인 tongue cleansing은 비효율적이다.• 기계적인 tongue cleansing은 단기간의 구취제거에는 효과가 있음을 이전 연구들은 보여왔지만,• 이 연구결과는 meridol HALITO...
Referencesl. Delanghe G, Bollen C, van Steenberghe D, Feenstra L. Multidisciplinairerurnpak van halitosis. Ned Tjschrifr v...
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송혜민 메인 Short term clinical efficacy of new meridol halitosis tooth & tongue gel in combination with a tongue cleaner to r

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송혜민 메인 Short term clinical efficacy of new meridol halitosis tooth & tongue gel in combination with a tongue cleaner to r

  1. 1. 2013. 5. 313조 발표자 : 36번 송혜민Short Term Clinical Efficacy of Newmeridol HALITOSIS tooth & tongue gel inCombination with a Tongue Cleaner toReduce Oral MalodorD. Wilhelm, A.Himmelmann, C.KrauseproDERM Institute for Applied DermatologicalResearch GmbH Schenefeld, Germany
  2. 2. • 87% 환자가 충치로 인해 구취를 겪고 있으며, 51%는 tongue coating, 17%는치은염, 15%는 치주염, 17%는 여러 복합요인이 있다.• 특히 혀의 뒷부분은 해부학적 구조에 의해 혐기성 세균의 서식처이다.• 혀의 배면에는 여러 종류의 papillae가 있고, filliform papillae는 구취의 주요 요인이다.•Tongue cleaner와 tooth and tongue gel을 이용하여, 구취를 줄일 수 있는지를gas chromatograph measure of VSCs를 이용하여 측정해 보았다.Introduction
  3. 3. • Study Design and Population1. single-center에서 (independent dermatological researchinstitute), examiner-blind, randomized, crossover superior design clinical study가 a seven-day wash-in and a seven-day wash-out period between treatments.2. 총 54 명의 구취 유발 구강 내 박테리아를 가진(organoleptic rating of 22, H2S [hydrogen sulphide] readings > 50 ppb, and CH3SH [methyl mercaptan]readings > 50 ppb) 비흡연 피실험자들(44 women, 10 men; average age 47.7years)로 구성. 44명의 피실험자들을 분석.3. Treatment A: no treatment (control)Treatment B: mechanical tongue cleaning with tongue cleanerTreatment C: meridol HALITOSIS tooth & tongue gel applied on tonguecleanerMaterials and Methods
  4. 4. • Wash-in and Wash-out Period• 최상의 구강 분석하기 위해서 baseline 측정을 위해 최소 일주일전에 피실험자들은 감독관의 지시를 받음.• 피실험자들은 standard fluoride toothpaste (1400 ppm F from sodiummonofluorophosphate)와 toothbrush를 받고 감독관들에게 일주일동안 하루에 두번 그리고 treatment 중간에 잇솔질을 하도록 지시받음.Materials and Methods• Test Materials. meridol HALITOSIS tooth & tongue gel: 1400 ppm Ffrom amine fluoride/stannous fluoride (ASF), 0.57o zinclactate, oral malodor counter actives. meridol HALITOSIS tonsue cleaner
  5. 5. • Application ModeMaterials and Methods
  6. 6. • Organoleptic Ratings (Ors)0 = Odor cannot be detected1 = Questionable malodor, barely detectable2 = Slight malodor, exceeds the threshold of malodorrecognition3 = Moderate malodor, that is definitely detected4 = Strong malodor5 = Very strong malodorMaterials and Methods• VSC Measurements Using a Gas Chromatograph
  7. 7. Materials and Methods• VSC Measurements Using a Gas ChromatographObjective measurementDetects VSC with appropriatemonitor; unableto differentiate individualsulphur compoundsHigher affinity to hydrogensulphide than dimethylsulphideSimple to perform but fails todetect oral malodour causedby non-sulphide components
  8. 8. • Organoleptic EvaluationResults
  9. 9. • VSC ConcentrationsResults
  10. 10. • 구취제거에는 기계적인 tongue cleansing은 비효율적이다.• 기계적인 tongue cleansing은 단기간의 구취제거에는 효과가 있음을 이전 연구들은 보여왔지만,• 이 연구결과는 meridol HALITOSIS tooth & tongue gel이 장기간의 구취제거에 효과적임을 보여주고 있다.• 혀 후방 cleansing이 구취제거뿐 아니라 구강 위생을 위해 중요함을 알아야 한다.Discussion
  11. 11. Referencesl. Delanghe G, Bollen C, van Steenberghe D, Feenstra L. Multidisciplinairerurnpak van halitosis. Ned Tjschrifr van Tandheelk 2008;105:314-7.2. Tonz-etich J. Production and origin of oral malodor. A review ofmechanisms and methods of analysis. J Perio&tntol 1977;48:13-20.3. De Boever EH, de Uzeda M, Loesche WJ. Relationship between volatilesulphur compounds, BANA-hydrolizing bacteria and gingival health inpatients with and without complaints of oral malodour. J Clin Dent1994,4:ll4-9.4. Bosy A, Kulkami GV, Rosenberg M, McCullmh CA. Relationship of oralmalodour to peri<xlontitis: evidence of independence in discretesubpopulation. J Perktdonnl 1994;65:31 46.5. Danser MM, Comez SM, van der Weijden CA. Tongue coating andtongue brushing: a literature review. lnl J Dent H1,g 2003;l:l5l-8.6. De Boever EH, Loesche WJ. The tongue microbiota and tongue sudacecheracteristics contribute to oral malodour. In: Bad Breath: AMultidisciltlinary- Appnach, van Steenberghe D, Rosenberg M, eds. l-euvenUniversity Press, pp. I I l-21,1996.

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