Healthcare Improvement Science (HIS) is an umbrella term that aims to increase efficiency, efficacy, quality, and outcomes in healthcare. [HIS] draws on knowledge from various sources including research. It serves as a connection between clinical work, management, leadership, and factors like multidisciplinary teams, patient safety, quality management, change management, and professional development. [HIS] encompasses all actions like practice, education, science, and policy that can lead to better health treatments, system performance, and professional learning to benefit communities. [HIS] requires flexibility and responsibility in understanding, theories of knowledge, and applying research evidence to healthcare improvement strategies.