The document discusses how knowledge translation (KT), which involves moving research into practice, can be a strategy for transformative change in healthcare. It outlines KT approaches at the Canadian Institutes of Health Research (CIHR), including end-of-grant KT and integrated KT. Integrated KT involves engaging stakeholders in the research process. The document argues that applying existing research more effectively and conducting the right collaborative, interdisciplinary research could significantly improve health outcomes. It asserts KT must focus on adapting research for local contexts and evaluating real-world impacts to drive transformative change.