Fluticasone furoate is a synthetic corticosteroid used in nasal sprays to treat symptoms of seasonal allergic rhinitis. It is an unscented, alcohol-free aqueous suspension that is administered via an atomizing nasal spray pump. The drug is derived from Fluticasone and is a new topical intranasal corticosteroid with high anti-inflammatory potency and low systemic exposure. It is synthesized through a six step process using flumethasone as a starting material, followed by particle size reduction. Major companies that produce Fluticasone include GSK, Teva, and Pfizer.