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Professor Neil R Poulter
Director Imperial Clinical Trials Unit
Imperial College London UK
President of The International Society of Hypertension (ISH)
3rd Vietnamese Congress of Hypertension
Nha Trang City: Vietnam
11th-13th May 2018
Global Trends in Hypertension and the
Impact of MMM
Health Statistics and Informatics
Deaths attributed to 19 leading factors,
by country income level, 2004
Global Burden of Disease Due to Risk Factors by
disease type: 2010
CV &
Circulatory
Lancet 2012
Lancet 2005;365:217-23
Hypertension: Size of the Problem - Global
Prospects
22.6
37.2 39.1
20.9
34.8
23.7
19.7
14.5
28.3
17.0
40.7
20.6
26.9
22.0
35.3
37.4
0
10
20
30
40
50 Men
Women
Prevalence of hypertension in people aged 20 years and older
Prevalence of hypertension is high
Kearney PM et al.,Lancet. 2005;365:217-223
44.5
27.7
18.8
42.5
45.9
23.6
40.2
17.1
28.227.0
24.022.9
39.1
41.6
27.027.0
0
10
20
30
40
50
Prevalenceofhypertension(%)
2000
2025
“Raised blood pressure continues to be
the biggest contributor to the global
burden of disease and to global mortality,
leading to 9.4 million deaths each year.”
Poulter et al. Lancet 2015
Development and Risk Factors
RISES FALLS
Age
Exercise
Alcohol intake
Salt intake
Potassium intake
Body weight
Stress
Smoking
Sat fats
?








Income level n Aware (%) Treated (%) Controlled
(%)
High 6263 49.0 46.7 19.0
Upper Middle 18123 52.5 48.3 15.6
Lower Middle 23269 43.6 36.9 9.9
Low 10185 40.8 31.7 12.7
Total 57840 46.5 40.6 13.2
Hypertension: Awareness, Treatment & Control†
by National Income: 2003 – 2009. PURE Study
† <140/90
Chow et al. JAMA 2013
Awareness Treatment and Control of
Hypertension. Health Survey for England (HSE)
1994 - 2011
Year Awareness
%
Treated
%
Controlled
%
1994 46 32 11
1998 53 39 15
2003 62 48 22
2006 66 54 28
2011 71 59 37
SBP≥ 140mmHg or DBP ≥ 90mmHg or on treatment for hypertension
Income level n Aware (%) Treated (%) Controlled
(%)
High 6263 49.0 46.7 19.0
Upper Middle 18123 52.5 48.3 15.6
Lower Middle 23269 43.6 36.9 9.9
Low 10185 40.8 31.7 12.7
Total 57840 46.5 40.6 13.2
Hypertension: Awareness, Treatment & Control†
by National Income: 2003 – 2009. PURE Study
† <140/90
Chow et al. JAMA 2013
ONLY 46.5% AWARENESS
IN 2017
World Hypertension Day
expanded to become
May Measurement
Month
A SIMPLE MEASURE TO SAVE LIVES #checkyourpressure
MMM17
AIMS:
To highlight the importance of measuring blood pressure
To identify and reduce the BPs of participants from over 100 countries
who require intervention according to
OBJECTIVES:
To recruit participants, aged >18 years, who ideally have not had their
BPs measured in the previous 12 months
To supply diet and lifestyle treatment advice to all those screened who
have BPs in the Hypertensive range
To use the data on untreated hypertension to motivate governments to
improve screening facilities and policies.
A SIMPLE MEASURE TO SAVE LIVES #checkyourpressure
WORLDWIDE COVERAGE
80 countries in total
A SIMPLE MEASURE TO SAVE LIVES #checkyourpressure
TOTAL NUMBERS BY REGION
Region Total Percentage
South-East Asia & Australasia 360,320 29.9%
South Asia 263,239 21.9%
East Asia 180,186 15.0%
Sub-Saharan Africa 130,508 10.8%
Europe 109,044 9.1%
Americas 107,714 8.9%
Northern Africa and Middle East 53,306 4.4%
Total 1,204,317
A SIMPLE MEASURE TO SAVE LIVES #checkyourpressure
WORLD BANK INCOME GROUPS
Income level Total Percentage
Low 18,953 1.6%
Lower middle 828,728 68.8%
Upper middle 240,853 20.0%
High 115,783 9.6%
Total 1,204,317
A SIMPLE MEASURE TO SAVE LIVES #checkyourpressure
COUNTRY NUMBERS (OVER 10,000)
Country Total Percentage
Philippines 271,883 22.6%
India 240,515 20.0%
China 125,239 10.4%
Indonesia 69,507 5.8%
Taiwan 52,606 4.4%
Ukraine 45,507 3.8%
Sudan 44,471 3.7%
Argentina 32,353 2.7%
Ivory Coast 24,563 2.0%
Colombia 22,277 1.9%
Venezuela 21,645 1.8%
Nigeria 19,931 1.7%
Angola 17,496 1.5%
Cameroon 16,093 1.3%
Kenya 14,863 1.2%
Bangladesh 11,418 1.0%
Viet Nam 10,996 0.9%
Italy 10,076 0.8%
A SIMPLE MEASURE TO SAVE LIVES #checkyourpressure
PARTICIPANT CHARACTERISTICS
Variable Total Percentage
On anti-hypertensive medication 240,249 20.0%
Diabetes 103,363 8.6%
Previous MI 37,859 3.2%
Previous stroke 22,006 1.8%
Pregnant 7,118 1.1%
Current smoker 138,928 11.5%
Alcohol intake 90,465 7.5%
A SIMPLE MEASURE TO SAVE LIVES #checkyourpressure
AGE AND SEX BY REGION
Region Mean age (years) Females Males On treatment
Europe 52.2 64,710 (59.6%) 43,942 (40.4%) 42,491 (39.0%)
Northern Africa and Middle East 37.4 19,738 (37.4%) 33,009 (62.6%) 1,742 (3.3%)
Sub-Saharan Africa 39.1 68,739 (54.1%) 58,399 (45.9%) 12,115 (9.3%)
Americas 48.8 64,136 (60.3%) 42,305 (39.8%) 32,319 (30.0%)
South Asia 40.3 118,776 (45.5%) 142,097 (54.5%) 3,612 (5.0%)
South-East Asia & Australasia 42.8 218,350 (61.1%) 138,907 (38.9%) 79,154 (22.0%)
East Asia 54.8 93,956 (53.3%) 82,329 (46.7%) 44,875 (24.9%)
A SIMPLE MEASURE TO SAVE LIVES #checkyourpressure
DIFFERENCE BETWEEN READINGS -
GLOBAL
Reading 1 Reading 2 Reading 3
Mean of 2 & 3
(round up)
Mean of 2 & 3
(round down)
SBP 126.4 124.5 123.3 124.1 123.7
DBP 79.5 78.5 77.9 78.4 78.1
Number of BP
Measurements
Total number*
1st 1,008,068
2nd 800,432
3rd 720,419
2nd and 3rd 701,299
* Not including data from Public Health
Foundation India
A SIMPLE MEASURE TO SAVE LIVES #checkyourpressure
HYPERTENSION
Defined as a BP of 140/90 or more or on treatment for BP
Proportion with hypertension Ω 30%
Number screened with Hypertension and not on treatment >150,000
Number on treatment and not controlled >100,000
Biggest national screen in 34 of 46 countries screened
A SIMPLE MEASURE TO SAVE LIVES #checkyourpressure
SCREENINGS TOOK PLACE AT
Churches
Market Places
Community spaces
Universities
Pharmacies
Supermarkets
Factories
… and people’s doorsteps
A SIMPLE MEASURE TO SAVE LIVES #checkyourpressure
PROMOTED IN MANY WAYS INCLUDING
Celebrity endorsement and TV
coverage (local celebrities who
have suffered from hypertension
– singers, actors, sports
celebrities)
Advertising in scientific journals
Awareness marches
Street Plays
Engagement of rural
community leaders
Endorsement from government
health officials
Cardiff Football Club
Size 8 Gospel Singer
Kenya
Awareness Marches Pakistan
A SIMPLE MEASURE TO SAVE LIVES #checkyourpressure
MMM17: PUBLICATION PLAN
Global Publication(s)
Regional Publications (x 8?)
National Publications (x 20?)
Ethnic Publications
Other ?
A SIMPLE MEASURE TO SAVE LIVES #checkyourpressure
MMM18 AIMS & OBJECTIVES
1. Increase awareness of the health issues around hypertension
– in the public and healthcare arenas
2. Create scientific evidence to inform and influence health policy – to
increase access to BP screening
3. Screen a further 1.5million+ people, who ideally haven’t
had their BP measured for over 1 year and collect quality data
A SIMPLE MEASURE TO SAVE LIVES #checkyourpressure
CAMPAIGN MESSAGES
MMM Strapline: A SIMPLE MEASURE TO SAVE LIVES
MMM call to action: #checkyourpressure
MMM 3 core messages:
A SIMPLE MEASURE TO SAVE LIVES #checkyourpressure
GLOBAL MEDIA CAMPAIGN
Dad, do I have
to talk til
I’m blue in
the face?
Get your
blood
pressure
checked.
Now.”
“
Remember how your parents
told you what to do?
Now it’s your turn.
Make sure your parents and loved ones get their blood pressure checked today
becauseisayso.net May Measurement Month
In 2018, MMM will be boosted by
a Servier global media campaign
This will increase public
awareness and drive interest for
MMM
MMM countries also have the
opportunity to approach local
Servier offices for support in their
screenings
Timing: Build interest in April.
Campaign launches 1st May
A SIMPLE MEASURE TO SAVE LIVES #checkyourpressure
NEW APP FOR 2018
Data collection and submission will be more simple and
faster!
For desktop/laptop, android/ IOS mobile phone or tablet
Offline data collection available
Default settings will reduce duplication of data entry
Scan and capture functionality to allow fast upload of hand
written forms
Available in several languages including English and Hindi
Guidelines and templates available early April
A SIMPLE MEASURE TO SAVE LIVES #checkyourpressure
& help us to save more
lives
MMM18
BE PART OF IT!
Please contact
manager@maymeasure.com
A SIMPLE MEASURE TO SAVE LIVES #checkyourpressure
MMM18 – 1 WEEK IN

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Cd2.11 global trends in hypertension and the impact of mmm vietnam - may 2018

  • 1. Professor Neil R Poulter Director Imperial Clinical Trials Unit Imperial College London UK President of The International Society of Hypertension (ISH) 3rd Vietnamese Congress of Hypertension Nha Trang City: Vietnam 11th-13th May 2018 Global Trends in Hypertension and the Impact of MMM
  • 2. Health Statistics and Informatics Deaths attributed to 19 leading factors, by country income level, 2004
  • 3. Global Burden of Disease Due to Risk Factors by disease type: 2010 CV & Circulatory Lancet 2012
  • 4. Lancet 2005;365:217-23 Hypertension: Size of the Problem - Global Prospects
  • 5. 22.6 37.2 39.1 20.9 34.8 23.7 19.7 14.5 28.3 17.0 40.7 20.6 26.9 22.0 35.3 37.4 0 10 20 30 40 50 Men Women Prevalence of hypertension in people aged 20 years and older Prevalence of hypertension is high Kearney PM et al.,Lancet. 2005;365:217-223 44.5 27.7 18.8 42.5 45.9 23.6 40.2 17.1 28.227.0 24.022.9 39.1 41.6 27.027.0 0 10 20 30 40 50 Prevalenceofhypertension(%) 2000 2025
  • 6.
  • 7. “Raised blood pressure continues to be the biggest contributor to the global burden of disease and to global mortality, leading to 9.4 million deaths each year.” Poulter et al. Lancet 2015
  • 8. Development and Risk Factors RISES FALLS Age Exercise Alcohol intake Salt intake Potassium intake Body weight Stress Smoking Sat fats ?        
  • 9. Income level n Aware (%) Treated (%) Controlled (%) High 6263 49.0 46.7 19.0 Upper Middle 18123 52.5 48.3 15.6 Lower Middle 23269 43.6 36.9 9.9 Low 10185 40.8 31.7 12.7 Total 57840 46.5 40.6 13.2 Hypertension: Awareness, Treatment & Control† by National Income: 2003 – 2009. PURE Study † <140/90 Chow et al. JAMA 2013
  • 10. Awareness Treatment and Control of Hypertension. Health Survey for England (HSE) 1994 - 2011 Year Awareness % Treated % Controlled % 1994 46 32 11 1998 53 39 15 2003 62 48 22 2006 66 54 28 2011 71 59 37 SBP≥ 140mmHg or DBP ≥ 90mmHg or on treatment for hypertension
  • 11. Income level n Aware (%) Treated (%) Controlled (%) High 6263 49.0 46.7 19.0 Upper Middle 18123 52.5 48.3 15.6 Lower Middle 23269 43.6 36.9 9.9 Low 10185 40.8 31.7 12.7 Total 57840 46.5 40.6 13.2 Hypertension: Awareness, Treatment & Control† by National Income: 2003 – 2009. PURE Study † <140/90 Chow et al. JAMA 2013 ONLY 46.5% AWARENESS
  • 12. IN 2017 World Hypertension Day expanded to become May Measurement Month
  • 13. A SIMPLE MEASURE TO SAVE LIVES #checkyourpressure MMM17 AIMS: To highlight the importance of measuring blood pressure To identify and reduce the BPs of participants from over 100 countries who require intervention according to OBJECTIVES: To recruit participants, aged >18 years, who ideally have not had their BPs measured in the previous 12 months To supply diet and lifestyle treatment advice to all those screened who have BPs in the Hypertensive range To use the data on untreated hypertension to motivate governments to improve screening facilities and policies.
  • 14. A SIMPLE MEASURE TO SAVE LIVES #checkyourpressure WORLDWIDE COVERAGE 80 countries in total
  • 15. A SIMPLE MEASURE TO SAVE LIVES #checkyourpressure TOTAL NUMBERS BY REGION Region Total Percentage South-East Asia & Australasia 360,320 29.9% South Asia 263,239 21.9% East Asia 180,186 15.0% Sub-Saharan Africa 130,508 10.8% Europe 109,044 9.1% Americas 107,714 8.9% Northern Africa and Middle East 53,306 4.4% Total 1,204,317
  • 16. A SIMPLE MEASURE TO SAVE LIVES #checkyourpressure WORLD BANK INCOME GROUPS Income level Total Percentage Low 18,953 1.6% Lower middle 828,728 68.8% Upper middle 240,853 20.0% High 115,783 9.6% Total 1,204,317
  • 17. A SIMPLE MEASURE TO SAVE LIVES #checkyourpressure COUNTRY NUMBERS (OVER 10,000) Country Total Percentage Philippines 271,883 22.6% India 240,515 20.0% China 125,239 10.4% Indonesia 69,507 5.8% Taiwan 52,606 4.4% Ukraine 45,507 3.8% Sudan 44,471 3.7% Argentina 32,353 2.7% Ivory Coast 24,563 2.0% Colombia 22,277 1.9% Venezuela 21,645 1.8% Nigeria 19,931 1.7% Angola 17,496 1.5% Cameroon 16,093 1.3% Kenya 14,863 1.2% Bangladesh 11,418 1.0% Viet Nam 10,996 0.9% Italy 10,076 0.8%
  • 18. A SIMPLE MEASURE TO SAVE LIVES #checkyourpressure PARTICIPANT CHARACTERISTICS Variable Total Percentage On anti-hypertensive medication 240,249 20.0% Diabetes 103,363 8.6% Previous MI 37,859 3.2% Previous stroke 22,006 1.8% Pregnant 7,118 1.1% Current smoker 138,928 11.5% Alcohol intake 90,465 7.5%
  • 19. A SIMPLE MEASURE TO SAVE LIVES #checkyourpressure AGE AND SEX BY REGION Region Mean age (years) Females Males On treatment Europe 52.2 64,710 (59.6%) 43,942 (40.4%) 42,491 (39.0%) Northern Africa and Middle East 37.4 19,738 (37.4%) 33,009 (62.6%) 1,742 (3.3%) Sub-Saharan Africa 39.1 68,739 (54.1%) 58,399 (45.9%) 12,115 (9.3%) Americas 48.8 64,136 (60.3%) 42,305 (39.8%) 32,319 (30.0%) South Asia 40.3 118,776 (45.5%) 142,097 (54.5%) 3,612 (5.0%) South-East Asia & Australasia 42.8 218,350 (61.1%) 138,907 (38.9%) 79,154 (22.0%) East Asia 54.8 93,956 (53.3%) 82,329 (46.7%) 44,875 (24.9%)
  • 20. A SIMPLE MEASURE TO SAVE LIVES #checkyourpressure DIFFERENCE BETWEEN READINGS - GLOBAL Reading 1 Reading 2 Reading 3 Mean of 2 & 3 (round up) Mean of 2 & 3 (round down) SBP 126.4 124.5 123.3 124.1 123.7 DBP 79.5 78.5 77.9 78.4 78.1 Number of BP Measurements Total number* 1st 1,008,068 2nd 800,432 3rd 720,419 2nd and 3rd 701,299 * Not including data from Public Health Foundation India
  • 21. A SIMPLE MEASURE TO SAVE LIVES #checkyourpressure HYPERTENSION Defined as a BP of 140/90 or more or on treatment for BP Proportion with hypertension Ω 30% Number screened with Hypertension and not on treatment >150,000 Number on treatment and not controlled >100,000 Biggest national screen in 34 of 46 countries screened
  • 22.
  • 23. A SIMPLE MEASURE TO SAVE LIVES #checkyourpressure SCREENINGS TOOK PLACE AT Churches Market Places Community spaces Universities Pharmacies Supermarkets Factories … and people’s doorsteps
  • 24. A SIMPLE MEASURE TO SAVE LIVES #checkyourpressure PROMOTED IN MANY WAYS INCLUDING Celebrity endorsement and TV coverage (local celebrities who have suffered from hypertension – singers, actors, sports celebrities) Advertising in scientific journals Awareness marches Street Plays Engagement of rural community leaders Endorsement from government health officials Cardiff Football Club Size 8 Gospel Singer Kenya Awareness Marches Pakistan
  • 25. A SIMPLE MEASURE TO SAVE LIVES #checkyourpressure MMM17: PUBLICATION PLAN Global Publication(s) Regional Publications (x 8?) National Publications (x 20?) Ethnic Publications Other ?
  • 26. A SIMPLE MEASURE TO SAVE LIVES #checkyourpressure MMM18 AIMS & OBJECTIVES 1. Increase awareness of the health issues around hypertension – in the public and healthcare arenas 2. Create scientific evidence to inform and influence health policy – to increase access to BP screening 3. Screen a further 1.5million+ people, who ideally haven’t had their BP measured for over 1 year and collect quality data
  • 27. A SIMPLE MEASURE TO SAVE LIVES #checkyourpressure CAMPAIGN MESSAGES MMM Strapline: A SIMPLE MEASURE TO SAVE LIVES MMM call to action: #checkyourpressure MMM 3 core messages:
  • 28. A SIMPLE MEASURE TO SAVE LIVES #checkyourpressure GLOBAL MEDIA CAMPAIGN Dad, do I have to talk til I’m blue in the face? Get your blood pressure checked. Now.” “ Remember how your parents told you what to do? Now it’s your turn. Make sure your parents and loved ones get their blood pressure checked today becauseisayso.net May Measurement Month In 2018, MMM will be boosted by a Servier global media campaign This will increase public awareness and drive interest for MMM MMM countries also have the opportunity to approach local Servier offices for support in their screenings Timing: Build interest in April. Campaign launches 1st May
  • 29. A SIMPLE MEASURE TO SAVE LIVES #checkyourpressure NEW APP FOR 2018 Data collection and submission will be more simple and faster! For desktop/laptop, android/ IOS mobile phone or tablet Offline data collection available Default settings will reduce duplication of data entry Scan and capture functionality to allow fast upload of hand written forms Available in several languages including English and Hindi Guidelines and templates available early April
  • 30. A SIMPLE MEASURE TO SAVE LIVES #checkyourpressure & help us to save more lives MMM18 BE PART OF IT! Please contact manager@maymeasure.com
  • 31. A SIMPLE MEASURE TO SAVE LIVES #checkyourpressure MMM18 – 1 WEEK IN