Health Evidence™ hosted a 60 minute webinar examining the effects of weight loss interventions for adults who are obese on mortality, cardiovascular disease and cancer. Follow this link to access to the audio recording for this webinar: https://youtu.be/olF1bvaofXE
Dr. Alison Avenell, Clinical Chair in Health Services Research, and Sam (Chenhan) Ma, from the Health Services Research Unit at the University of Aberdeen presented an overview of findings from their latest systematic review and meta-analysis:
Ma C, Avenell A, Bolland M, Hudson J, Stewart F, Robertson C, et al. (2017). Effects of weight loss interventions for adults who are obese on mortality, cardiovascular disease, and cancer: Systematic review and meta-analysis. BMJ, 359, j4849.
Adults with obesity have an increased risk of premature mortality, cardiovascular disease, some cancers, type 2 diabetes, and many other diseases. This review assesses whether weight loss intervention for adults with obesity affect all cause, cardiovascular, and cancer mortality, cardiovascular disease, cancer, and body weight. Fifty-four randomized controlled trials (RCTs) with 30,206 participants were identified in the review. High quality evidence showed that weight loss interventions decrease all cause mortality, with six fewer deaths per 1000 participants. Moderate quality evidence showed an effect on cardiovascular mortality, and very low quality evidence showed an effect on cancer mortality. Weight reducing diets, usually low in fat and saturated fat, with or without exercise advice or programmes, may reduce premature all cause mortality in adults with obesity.