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STUDY OF GAS
CHROMATOGRAPHY FOR
MEDICAL APPLICATIONS
Done by
Taif Alawsi
INTRODUCTION
Chromatography –’colour’
and ‘to write”.
Basically it is a broad range of
physical methods used to
separate and /or to analyse
complex mixtures.
Components to be separated
are distributed between two
phases :a stationary phase
bed and a mobile phase
which flows through the
stationary bed.
Schematic Diagram of GC
Individual species are retained by the stationary
phase (packing) based on various interactions
such as surface adsorption, relative solubility of
the sample in the mobile phase and charge.
APPLICATIONS
Exhaled species often reflect the health
conditions of the human body.
To date, many investigations have been
conducted for diagnostics of health
conditions and disease based on analysis of
breath air . Breath analysis has many
applications and so is of great interest.
Exhaled NO: It’s the most interesting target of
medical gas analysis is exhaled nitric oxide
(eNO), especially as a marker of asthma.
Halitosis: Halitosis is caused by NH3 , amines,
and most importantly certain sulfur gases, such
as H2S, CH3SH, dimethylsulfide (DMS).
Study of gas chromatography for medical applications

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Study of gas chromatography for medical applications

  • 1. STUDY OF GAS CHROMATOGRAPHY FOR MEDICAL APPLICATIONS Done by Taif Alawsi
  • 2. INTRODUCTION Chromatography –’colour’ and ‘to write”. Basically it is a broad range of physical methods used to separate and /or to analyse complex mixtures. Components to be separated are distributed between two phases :a stationary phase bed and a mobile phase which flows through the stationary bed. Schematic Diagram of GC
  • 3. Individual species are retained by the stationary phase (packing) based on various interactions such as surface adsorption, relative solubility of the sample in the mobile phase and charge.
  • 4. APPLICATIONS Exhaled species often reflect the health conditions of the human body. To date, many investigations have been conducted for diagnostics of health conditions and disease based on analysis of breath air . Breath analysis has many applications and so is of great interest.
  • 5. Exhaled NO: It’s the most interesting target of medical gas analysis is exhaled nitric oxide (eNO), especially as a marker of asthma. Halitosis: Halitosis is caused by NH3 , amines, and most importantly certain sulfur gases, such as H2S, CH3SH, dimethylsulfide (DMS).