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M R Sumon Sarkar
Contents:
 What is Pharmacology
Future:
 Present:
 Academics
 Research
 Industries
 Special Domains
 Proteomics
 Pharmacogenomics & pharmacogenetics
 Bioinformatics
 Nanomedicine
 History
 Summary
 The study of drugs, their sources, their nature, and their
properties. Pharmacology is the study of the body's
reaction to drugs.
What is Pharmacology?
 Drug : A chemical substance that
is used for diagnosis, prevention
& treatment of disease.
 Pharmacon means drug and logos means study.
 Oswald Schmiedeberg
• Father of Modern Pharmacology
Past.....
 History
Rudolph Bucheim
• First laboratory for drug research
• Investigation of drug is a task of
pharmacologist
Research
Scope of pharmacology at present:
Undergraduate education:
Academics
Postgraduate education:
Industries
 Medical advisor
 Medical transcription
 Medico marketing
 Product management
 Contract research organization
 Training
 Research: new drug development
 Drug development.
Research
Drug discovery.
Clinical trial.
Proteomics
Pharmacogenomics
and pharmacogenetics
Bioinformatics
Nanomedicine
Proteomics
 Proteomics is the large-scale study of proteins, particularly their
structures and functions.
Disease mechanism or drug effects
both affect a protein profile.
Proteomics aids the progress in
disease treatment.
Pharmacogenomics and pharmacogenetics
Pharmacogenomics is use of genetic information to guide the choice of drug
and dose.
 Role of pharmacogenomics:
• New drug discovery
• Minimizing adverse drug reactions
• Identification of responder and nonresponder
 Pharmacogenetics is study of genetic basis for
variability in drug response.
 Role of pharmacogenetics:
• Specific development of new drug
• Molecular diagnostic tests will be developed
Bioinformatics is the unified discipline formed from the combination of
biology, computer science, and information technology.
The primary goal of bioinformatics is to increase the
understanding of biological processes.
The mathematical, statistical and
computing methods that aim to solve
biological problems using DNA and
amino acid sequences and related
information
Nanomedicine
 Monitoring, repair, construction and control human biological systems at
the molecular level using engineered nanodevices and nanostructures.
Improve pharmacodynamics and kinetic profiles toward
safer and effective treatment.
Nanomedicine offers delivery of potential
drugs.
Current applications of nanotechnology in
medicine range from research involving
diagnostic devices and drug delivery vehicles
to robots that can enter the body and perform
specific tasks.
• The scope of pharmacology has expanded greatly over the last
decade to incorporate many new approaches such as computer-
assisted drug design, genetic screens, protein engineering and use of
novel drug delivery vehicles including viruses and artificial cells.
• Our society needs pharmacologists who understand the basis of
modern therapeutics for careers within academic, pharmaceutical
and governmental laboratories to study and develop tomorrow’s
drugs.
• Pharmacology is backbone of medicine
summary
Scope of pharmacology

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Scope of pharmacology

  • 1. M R Sumon Sarkar
  • 2.
  • 3. Contents:  What is Pharmacology Future:  Present:  Academics  Research  Industries  Special Domains  Proteomics  Pharmacogenomics & pharmacogenetics  Bioinformatics  Nanomedicine  History  Summary
  • 4.  The study of drugs, their sources, their nature, and their properties. Pharmacology is the study of the body's reaction to drugs. What is Pharmacology?  Drug : A chemical substance that is used for diagnosis, prevention & treatment of disease.  Pharmacon means drug and logos means study.
  • 5.  Oswald Schmiedeberg • Father of Modern Pharmacology Past.....  History Rudolph Bucheim • First laboratory for drug research • Investigation of drug is a task of pharmacologist
  • 9. Industries  Medical advisor  Medical transcription  Medico marketing  Product management  Contract research organization  Training  Research: new drug development
  • 10.
  • 11.  Drug development. Research Drug discovery. Clinical trial.
  • 13. Proteomics  Proteomics is the large-scale study of proteins, particularly their structures and functions. Disease mechanism or drug effects both affect a protein profile. Proteomics aids the progress in disease treatment.
  • 14. Pharmacogenomics and pharmacogenetics Pharmacogenomics is use of genetic information to guide the choice of drug and dose.  Role of pharmacogenomics: • New drug discovery • Minimizing adverse drug reactions • Identification of responder and nonresponder  Pharmacogenetics is study of genetic basis for variability in drug response.  Role of pharmacogenetics: • Specific development of new drug • Molecular diagnostic tests will be developed
  • 15. Bioinformatics is the unified discipline formed from the combination of biology, computer science, and information technology. The primary goal of bioinformatics is to increase the understanding of biological processes. The mathematical, statistical and computing methods that aim to solve biological problems using DNA and amino acid sequences and related information
  • 16. Nanomedicine  Monitoring, repair, construction and control human biological systems at the molecular level using engineered nanodevices and nanostructures. Improve pharmacodynamics and kinetic profiles toward safer and effective treatment. Nanomedicine offers delivery of potential drugs. Current applications of nanotechnology in medicine range from research involving diagnostic devices and drug delivery vehicles to robots that can enter the body and perform specific tasks.
  • 17. • The scope of pharmacology has expanded greatly over the last decade to incorporate many new approaches such as computer- assisted drug design, genetic screens, protein engineering and use of novel drug delivery vehicles including viruses and artificial cells. • Our society needs pharmacologists who understand the basis of modern therapeutics for careers within academic, pharmaceutical and governmental laboratories to study and develop tomorrow’s drugs. • Pharmacology is backbone of medicine summary